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Volumn 464, Issue 6, 2012, Pages 657-669

The influence of high glucose on the aerobic metabolism of endothelial EA.hy926 cells

Author keywords

Endothelial cells; Hyperglycaemia; Mitochondrial respiration; Oxidative metabolism; Uncoupling protein

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; AMINO ACID DERIVATIVE; GLUCOSE; GLUTAMINE; GLYCEROPHOSPHATE; HEXOKINASE 1; LACTATE DEHYDROGENASE; LIPID; MANGANESE SUPEROXIDE DISMUTASE; PALMITIC ACID; PALMITOYLCARNITINE; PYRUVATE DEHYDROGENASE; PYRUVIC ACID; REACTIVE OXYGEN METABOLITE; UBIDECARENONE; UBIQUITIN PROTEIN LIGASE E3; UNCOUPLING PROTEIN 2;

EID: 84873711521     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-012-1156-1     Document Type: Article
Times cited : (74)

References (32)
  • 1
    • 20044376702 scopus 로고    scopus 로고
    • The pathology of diabetic complications: A unifying mechanism
    • Brownlee M (2005) The pathology of diabetic complications: a unifying mechanism. Diabetes 54:1615-1625
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 2
    • 33748194692 scopus 로고    scopus 로고
    • Expression modification of uncoupling proteins and MnSOD in retinal endothelial cells and pericytes induced by high glucose: The role of reactive oxygen species in diabetic retinopathy
    • Cui Y, Xu X, Bi H, Zhu Q, Wu J, Xia X, Ren Q, Ho PC (2006) Expression modification of uncoupling proteins and MnSOD in retinal endothelial cells and pericytes induced by high glucose: the role of reactive oxygen species in diabetic retinopathy. Exp Eye Res 83:807-816
    • (2006) Exp Eye Res , vol.83 , pp. 807-816
    • Cui, Y.1    Xu, X.2    Bi, H.3    Zhu, Q.4    Wu, J.5    Xia, X.6    Ren, Q.7    Ho, P.C.8
  • 3
    • 0035933369 scopus 로고    scopus 로고
    • Acute regulation of fatty acid oxidation and AMP-activated protein kinase in human umbilical vein endothelial cells
    • Dagher Z, Ruderman N, Tornheim K, Ido Y (2001) Acute regulation of fatty acid oxidation and AMP-activated protein kinase in human umbilical vein endothelial cells. Circ Res 88:1276-1282
    • (2001) Circ Res , vol.88 , pp. 1276-1282
    • Dagher, Z.1    Ruderman, N.2    Tornheim, K.3    Ido, Y.4
  • 4
    • 77956804126 scopus 로고    scopus 로고
    • Endothelial mitochondria and heart disease
    • Davidson SM (2010) Endothelial mitochondria and heart disease. Cardiovasc Res 88:58-66
    • (2010) Cardiovasc Res , vol.88 , pp. 58-66
    • Davidson, S.M.1
  • 5
    • 34247598856 scopus 로고    scopus 로고
    • Endothelial mitochondria: Contributing to vascular function and disease
    • Davidson SM, Duchen MR (2007) Endothelial mitochondria: contributing to vascular function and disease. Circ Res 100:1128-1141
    • (2007) Circ Res , vol.100 , pp. 1128-1141
    • Davidson, S.M.1    Duchen, M.R.2
  • 6
    • 77249126523 scopus 로고    scopus 로고
    • Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species
    • Dranka BP, Hill BG, Darley-Usmar VM (2010) Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species. Free Radical Biol Med 48:905-914
    • (2010) Free Radical Biol Med , vol.48 , pp. 905-914
    • Dranka, B.P.1    Hill, B.G.2    Darley-Usmar, V.M.3
  • 7
    • 0035180299 scopus 로고    scopus 로고
    • Hyperglycaemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
    • Du XL, Edelstein D, Dimmeler S, Ju Q, Sui C, Brownlee M (2001) Hyperglycaemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. J Clin Invest 108:1341-1348
    • (2001) J Clin Invest , vol.108 , pp. 1341-1348
    • Du, X.L.1    Edelstein, D.2    Dimmeler, S.3    Ju, Q.4    Sui, C.5    Brownlee, M.6
  • 8
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
    • Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, Wu J, Brownlee M (2000) Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci USA 97:12222-12226
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12222-12226
    • Du, X.L.1    Edelstein, D.2    Rossetti, L.3    Fantus, I.G.4    Goldberg, H.5    Ziyadeh, F.6    Wu, J.7    Brownlee, M.8
  • 9
    • 48249085391 scopus 로고    scopus 로고
    • Oxidative stress as a major culprit in kidney disease in diabetes
    • Forbes JM, Coughlan MT, Cooper ME (2008) Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes 57:1446-1454
    • (2008) Diabetes , vol.57 , pp. 1446-1454
    • Forbes, J.M.1    Coughlan, M.T.2    Cooper, M.E.3
  • 11
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco FF, Brownlee M (2010) Oxidative stress and diabetic complications. Circ Res 107:1058-1070
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.F.1    Brownlee, M.2
  • 12
    • 0030009314 scopus 로고    scopus 로고
    • BCL-2 expression or antioxidants prevents hyperglycaemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells
    • Giardino I, Edelstein D, Brownlee M (1996) BCL-2 expression or antioxidants prevents hyperglycaemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells. J Clin Invest 97:1422-1428
    • (1996) J Clin Invest , vol.97 , pp. 1422-1428
    • Giardino, I.1    Edelstein, D.2    Brownlee, M.3
  • 14
    • 0029856982 scopus 로고    scopus 로고
    • Thiamine corrects delayed replication and decreases production of lactate and advanced glycation end-products in bovine retinal and human umbilical vein endothelial cells cultured under high glucose conditions
    • La Selva M, Beltramol E, Pagnozzi F, Bena E, Molinatti PA, Molinatti GM, Porta M (1996) Thiamine corrects delayed replication and decreases production of lactate and advanced glycation end-products in bovine retinal and human umbilical vein endothelial cells cultured under high glucose conditions. Diabetologia 39:1263-1268
    • (1996) Diabetologia , vol.39 , pp. 1263-1268
    • La Selva, M.1    Beltramol, E.2    Pagnozzi, F.3    Bena, E.4    Molinatti, P.A.5    Molinatti, G.M.6    Porta, M.7
  • 16
    • 35848963373 scopus 로고    scopus 로고
    • Bioenergetic and antioxidant properties of coenzyme Q10: Recent developments
    • Littaru GP, Tain L (2007) Bioenergetic and antioxidant properties of coenzyme Q10: recent developments. Mol Biotechnol 37:31-37
    • (2007) Mol Biotechnol , vol.37 , pp. 31-37
    • Littaru, G.P.1    Tain, L.2
  • 20
    • 0031940054 scopus 로고    scopus 로고
    • Review of alterations in endothelial nitric oxide production in diabetes
    • Pieper GM (1998) Review of alterations in endothelial nitric oxide production in diabetes. Hypertension 31:1047-1060
    • (1998) Hypertension , vol.31 , pp. 1047-1060
    • Pieper, G.M.1
  • 22
    • 0035988181 scopus 로고    scopus 로고
    • Vascular targets of redox signalling in diabetes mellitus
    • Spitaler MM, Graier WF (2002) Vascular targets of redox signalling in diabetes mellitus. Diabetologia 45:476-494
    • (2002) Diabetologia , vol.45 , pp. 476-494
    • Spitaler, M.M.1    Graier, W.F.2
  • 23
    • 11144262141 scopus 로고    scopus 로고
    • Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells
    • Srinivasan S, Hatley ME, Bolick DT, Palmer LA, Edelstein D, Brownlee M, Hedrick CC (2004) Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells. Diabetologia 47:1727-1734
    • (2004) Diabetologia , vol.47 , pp. 1727-1734
    • Srinivasan, S.1    Hatley, M.E.2    Bolick, D.T.3    Palmer, L.A.4    Edelstein, D.5    Brownlee, M.6    Hedrick, C.C.7
  • 24
    • 64149104209 scopus 로고    scopus 로고
    • Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration
    • Sweet IR, Gilbert M, Maloney E, Hockenbery DM, Schwartz MW, Kim F (2009) Endothelial inflammation induced by excess glucose is associated with cytosolic glucose 6-phosphate but not increased mitochondrial respiration. Diabetologia 52:921-931
    • (2009) Diabetologia , vol.52 , pp. 921-931
    • Sweet, I.R.1    Gilbert, M.2    Maloney, E.3    Hockenbery, D.M.4    Schwartz, M.W.5    Kim, F.6
  • 25
    • 70450214746 scopus 로고    scopus 로고
    • Uncoupling protein 1 inhibition by purine nucleotides is under control of the endogenous ubiquinone redox state
    • Swida-Barteczka A, Woyda-Ploszczyca A, Sluse F, Jarmuszkiewicz W (2009) Uncoupling protein 1 inhibition by purine nucleotides is under control of the endogenous ubiquinone redox state. Biochem J 424:297-306
    • (2009) Biochem J , vol.424 , pp. 297-306
    • Swida-Barteczka, A.1    Woyda-Ploszczyca, A.2    Sluse, F.3    Jarmuszkiewicz, W.4
  • 26
    • 0037046203 scopus 로고    scopus 로고
    • Adaptation and maladaptation of the heart in diabetes: I. General concepts
    • Taegtmeyer H, McNulty P, Young ME (2002) Adaptation and maladaptation of the heart in diabetes: I. General concepts. Circulation 105:1727-1733
    • (2002) Circulation , vol.105 , pp. 1727-1733
    • Taegtmeyer, H.1    McNulty, P.2    Young, M.E.3
  • 27
    • 0142150051 scopus 로고    scopus 로고
    • Mitochondrial formation of reactive oxygen species
    • Turrens JF (2003) Mitochondrial formation of reactive oxygen species. J Physiol 552:335-344
    • (2003) J Physiol , vol.552 , pp. 335-344
    • Turrens, J.F.1
  • 28
    • 78249255197 scopus 로고    scopus 로고
    • Ubiquinol (QH (2)) functions as a negative regulator of purine nucleotide inhibition of Acanthamoeba castellanii mitochondrial uncoupling protein
    • Woyda-Ploszczyca A, Jarmuszkiewicz W (2011) Ubiquinol (QH (2)) functions as a negative regulator of purine nucleotide inhibition of Acanthamoeba castellanii mitochondrial uncoupling protein. Biochim Biophys Acta 1807:42-52
    • (2011) Biochim Biophys Acta , vol.1807 , pp. 42-52
    • Woyda-Ploszczyca, A.1    Jarmuszkiewicz, W.2
  • 29
    • 58149358854 scopus 로고    scopus 로고
    • Upregulation of mitochondrial uncoupling protein-2 attenuates oxidative stress in diabetes
    • Xie Z, Zhang J, Wu J, Viollrt B, Zou MH (2008) Upregulation of mitochondrial uncoupling protein-2 attenuates oxidative stress in diabetes. Diabetes 57:3222-3230
    • (2008) Diabetes , vol.57 , pp. 3222-3230
    • Xie, Z.1    Zhang, J.2    Wu, J.3    Viollrt, B.4    Zou, M.H.5
  • 30
    • 34250825264 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species-mediated signalling in endothelial cells
    • Zhang DX, Gutterman DD (2007) Mitochondrial reactive oxygen species-mediated signalling in endothelial cells. Am J Physiol Heart Circ Physiol 292:H2023-H2031
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Zhang, D.X.1    Gutterman, D.D.2
  • 31
    • 64649091717 scopus 로고    scopus 로고
    • Protective effect of perindopril on diabetic retinopathy is associated with decreased vascular endothelial growth factor-to-pigment epithelium-derived factor ratio: Involvement of amitochondria-reactive oxygen species pathway
    • Zheng Z, Chen H, Ke G, Fan Y, Zou H, Sun X, Gu Q, Xu X, Ho PC (2009) Protective effect of perindopril on diabetic retinopathy is associated with decreased vascular endothelial growth factor-to-pigment epithelium-derived factor ratio: involvement of amitochondria-reactive oxygen species pathway. Diabetes 58:954-964
    • (2009) Diabetes , vol.58 , pp. 954-964
    • Zheng, Z.1    Chen, H.2    Ke, G.3    Fan, Y.4    Zou, H.5    Sun, X.6    Gu, Q.7    Xu, X.8    Ho, P.C.9
  • 32
    • 75749084898 scopus 로고    scopus 로고
    • Inhibition of JAK2/STAT3-mediated VEGF upregulation under high glucose conditions by PEDF trough a mitochondrial ROS pathway in vitro
    • Zheng Z, Chen H, Zhao H, Liu K, Luo D, Chen Y, Chen Y, Yang X, Gu Q, Xu X (2010) Inhibition of JAK2/STAT3-mediated VEGF upregulation under high glucose conditions by PEDF trough a mitochondrial ROS pathway in vitro. Invest Ophthalmol Vis Sci 51:64-71
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 64-71
    • Zheng, Z.1    Chen, H.2    Zhao, H.3    Liu, K.4    Luo, D.5    Chen, Y.6    Chen, Y.7    Yang, X.8    Gu, Q.9    Xu, X.10


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