Isoflurane Increases Neuronal Cell Death Vulnerability by Downregulating miR-214

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Yan, Hailiang ^a,d   Xu, Tao ^a,d   Zhao, Hongfeng ^c   Lee, Kuo Chieh ^b   Wang, Hoau Yan ^b   Zhang, Yan ^a,d  

^a PEKING UNIVERSITY   (China)

^b CITY UNIVERSITY OF NEW YORK MEDICAL SCHOOL   (United States)

^c Beijing No 4 High School   (China)

^d PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; ISOFLURANE; MICRORNA 214; PROTEIN BAX;

ADULT; AGED; ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FRONTAL CORTEX; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; NERVE CELL NECROSIS; NEUROTOXICITY; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; RAT;

ANIMALS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CELL DEATH; CELLS, CULTURED; DOWN-REGULATION; ISOFLURANE; MICRORNAS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84873692703     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055276     Document Type: Article

References (53)

1. Price DL, Sisodia SS, Gandy SE, (1995) Amyloid beta amyloidosis in Alzheimer's disease. Curr Opin Neurol 8: 268-274.
2. Bianchi SL, Tran T, Liu C, Lin S, Li Y, et al. (2008) Brain and behavior changes in 12-month-old Tg2576 and nontransgenic mice exposed to anesthetics. Neurobiol Aging 29: 1002-1010.
3. Muravchick S, Smith DS, (1995) Parkinsonian symptoms during emergence from general anesthesia. Anesthesiology 82: 305-307.
4. Culley DJ, Baxter M, Yukhananov R, Crosby G (2003) The memory effects of general anesthesia persist for weeks in young and aged rats. Anesth Analg 96: 1004-1009, table of contents.
5. Culley DJ, Baxter MG, Crosby CA, Yukhananov R, Crosby G (2004) Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats. Anesth Analg 99: 1393-1397; table of contents.
6. Culley DJ, Baxter MG, Yukhananov R, Crosby G, (2004) Long-term impairment of acquisition of a spatial memory task following isoflurane-nitrous oxide anesthesia in rats. Anesthesiology 100: 309-314.
7. Jevtovic-Todorovic V, Hartman RE, Izumi Y, Benshoff ND, Dikranian K, et al. (2003) Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci 23: 876-882.
8. Kvolik S, Glavas-Obrovac L, Bares V, Karner I, (2005) Effects of inhalation anesthetics halothane, sevoflurane, and isoflurane on human cell lines. Life Sci 77: 2369-2383.
9. Loop T, Dovi-Akue D, Frick M, Roesslein M, Egger L, et al. (2005) Volatile anesthetics induce caspase-dependent, mitochondria-mediated apoptosis in human T lymphocytes in vitro. Anesthesiology 102: 1147-1157.
10. Wei H, Kang B, Wei W, Liang G, Meng QC, et al. (2005) Isoflurane and sevoflurane affect cell survival and BCL-2/BAX ratio differently. Brain Res 1037: 139-147.
11. Yon JH, Daniel-Johnson J, Carter LB, Jevtovic-Todorovic V, (2005) Anesthesia induces neuronal cell death in the developing rat brain via the intrinsic and extrinsic apoptotic pathways. Neuroscience 135: 815-827.
12. Xie Z, Dong Y, Maeda U, Alfille P, Culley DJ, et al. (2006) The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels. Anesthesiology 104: 988-994.
13. Xie Z, Tanzi RE, (2006) Alzheimer's disease and post-operative cognitive dysfunction. Exp Gerontol 41: 346-359.
14. Breteler MM, van Duijn CM, Chandra V, Fratiglioni L, Graves AB, et al. (1991) Medical history and the risk of Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group. Int J Epidemiol 20Suppl 2: S36-42.
15. Bohnen NI, Warner MA, Kokmen E, Beard CM, Kurland LT, (1994) Alzheimer's disease and cumulative exposure to anesthesia: a case-control study. J Am Geriatr Soc 42: 198-201.
16. Gasparini M, Vanacore N, Schiaffini C, Brusa L, Panella M, et al. (2002) A case-control study on Alzheimer's disease and exposure to anesthesia. Neurol Sci 23: 11-14.
17. Lee TA, Wolozin B, Weiss KB, Bednar MM, (2005) Assessment of the emergence of Alzheimer's disease following coronary artery bypass graft surgery or percutaneous transluminal coronary angioplasty. J Alzheimers Dis 7: 319-324.
18. Zuo C, Zuo Z, (2010) Spine Surgery under general anesthesia may not increase the risk of Alzheimer's disease. Dement Geriatr Cogn Disord 29: 233-239.
19. Eckenhoff RG, Johansson JS, Wei H, Carnini A, Kang B, et al. (2004) Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity. Anesthesiology 101: 703-709.
20. Ghirlanda G, Hilcove SA, Pidikiti R, Johansson JS, Lear JD, et al. (2004) Volatile anesthetic modulation of oligomerization equilibria in a hexameric model peptide. FEBS Lett 578: 140-144.
21. Eckenhoff RG, Johansson JS, (1997) Molecular interactions between inhaled anesthetics and proteins. Pharmacol Rev 49: 343-367.
22. Eckenhoff RG, (2001) Promiscuous ligands and attractive cavities: how do the inhaled anesthetics work? Mol Interv 1: 258-268.
23. Liu R, Loll PJ, Eckenhoff RG, (2005) Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein. FASEB J 19: 567-576.
24. Carnini A, Lear JD, Eckenhoff RG, (2007) Inhaled anesthetic modulation of amyloid beta(1-40) assembly and growth. Curr Alzheimer Res 4: 233-241.
25. Zhang B, Dong Y, Zhang G, Moir RD, Xia W, et al. (2008) The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions. J Biol Chem 283: 11866-11875.
26. Mandal PK, Pettegrew JW, (2008) Abeta peptide interactions with isoflurane, propofol, thiopental and combined thiopental with halothane: a NMR study. Biochim Biophys Acta 1778: 2633-2639.
27. Mandal PK, Fodale V, (2009) Isoflurane and desflurane at clinically relevant concentrations induce amyloid beta-peptide oligomerization: an NMR study. Biochem Biophys Res Commun 379: 716-720.
28. Planel E, Richter KE, Nolan CE, Finley JE, Liu L, et al. (2007) Anesthesia leads to tau hyperphosphorylation through inhibition of phosphatase activity by hypothermia. J Neurosci 27: 3090-3097.
29. Planel E, Krishnamurthy P, Miyasaka T, Liu L, Herman M, et al. (2008) Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo. J Neurosci 28: 12798-12807.
30. Planel E, Bretteville A, Liu L, Virag L, Du AL, et al. (2009) Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia. FASEB J 23: 2595-2604.
31. Whittington RA, Papon MA, Chouinard F, Planel E, (2010) Hypothermia and Alzheimer's disease neuropathogenic pathways. Curr Alzheimer Res 7: 717-725.
32. Run X, Liang Z, Gong CX, (2010) Anesthetics and tau protein: animal model studies. J Alzheimers Dis 22Suppl 3: 49-55.
33. Papon MA, Whittington RA, El-Khoury NB, Planel E, (2011) Alzheimer's disease and anesthesia. Front Neurosci 4: 272.
34. Whittington RA, Virag L, Marcouiller F, Papon MA, El Khoury NB, et al. (2011) Propofol directly increases tau phosphorylation. PLoS One 6: e16648.
35. Dong Y, Wu X, Xu Z, Zhang Y, Xie Z, (2012) Anesthetic isoflurane increases phosphorylated tau levels mediated by caspase activation and Abeta generation. PLoS One 7: e39386.
36. Zhang Y, McLaughlin R, Goodyer C, LeBlanc A, (2002) Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons. J Cell Biol 156: 519-529.
37. Zhang Y, Hong Y, Bounhar Y, Blacker M, Roucou X, et al. (2003) p75 neurotrophin receptor protects primary cultures of human neurons against extracellular amyloid beta peptide cytotoxicity. J Neurosci 23: 7385-7394.
38. Liang G, Wang Q, Li Y, Kang B, Eckenhoff MF, et al. (2008) A presenilin-1 mutation renders neurons vulnerable to isoflurane toxicity. Anesth Analg 106: 492-500, table of contents.
39. Wei H, Liang G, Yang H, Wang Q, Hawkins B, et al. (2008) The common inhalational anesthetic isoflurane induces apoptosis via activation of inositol 1,4,5-trisphosphate receptors. Anesthesiology 108: 251-260.
40. Zhen Y, Dong Y, Wu X, Xu Z, Lu Y, et al. (2009) Nitrous oxide plus isoflurane induces apoptosis and increases beta-amyloid protein levels. Anesthesiology 111: 741-752.
41. Dong Y, Zhang G, Zhang B, Moir RD, Xia W, et al. (2009) The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels. Arch Neurol 66: 620-631.
42. Olney JW, Young C, Wozniak DF, Ikonomidou C, Jevtovic-Todorovic V, (2004) Anesthesia-induced developmental neuroapoptosis. Does it happen in humans? Anesthesiology 101: 273-275.
43. Hudson AE, Hemmings HC Jr, (2011) Are anaesthetics toxic to the brain? Br J Anaesth 107: 30-37.
44. Zhang Y, Dong Y, Wu X, Lu Y, Xu Z, et al. (2010) The mitochondrial pathway of anesthetic isoflurane-induced apoptosis. J Biol Chem 285: 4025-4037.
45. Mallick B, Ghosh Z, (2011) A complex crosstalk between polymorphic microRNA target sites and AD prognosis. RNA Biol 8: 665-673.
46. Fodale V, Santamaria LB (2003) Drugs of anesthesia, central nicotinic receptors and post-operative cognitive dysfunction. Acta Anaesthesiol Scand 47: 1180; author reply 1181.
47. Su D, Zhao Y, Wang B, Xu H, Li W, et al. (2011) Isoflurane-induced spatial memory impairment in mice is prevented by the acetylcholinesterase inhibitor donepezil. PLoS One 6: e27632.
48. Rodriguez JA, Buzaleh AM, Fossati M, Azcurra J, Batlle AM, (2002) The effects of some porphyrinogenic drugs on the brain cholinergic system. Cell Mol Biol (Noisy-le-grand) 48: 103-110.
49. Fodale V, Quattrone D, Trecroci C, Caminiti V, Santamaria LB, (2006) Alzheimer's disease and anaesthesia: implications for the central cholinergic system. Br J Anaesth 97: 445-452.
50. Perry E, Walker M, Grace J, Perry R, (1999) Acetylcholine in mind: a neurotransmitter correlate of consciousness? Trends Neurosci 22: 273-280.
51. Zhang Y, Goodyer C, LeBlanc A, (2000) Selective and protracted apoptosis in human primary neurons microinjected with active caspase-3,-6,-7, and-8. J Neurosci 20: 8384-8389.
52. McKhann G, Drachman D, Folstein M, Katzman R, Price D, et al. (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34: 939-944.
53. Hyman BT, Trojanowski JQ, (1997) Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer disease. J Neuropathol Exp Neurol 56: 1095-1097.