Alzheimer's disease and anaesthesia: Implications for the central cholinergic system

British Journal of Anaesthesia

Volumn 97, Issue 4, 2006, Pages 445-452

  Fodale, V ^a   Quattrone, D ^a   Trecroci, C ^a   Caminiti, V ^a   Santamaria, L B ^a  

^a UNIVERSITY OF MESSINA   (Italy)

Author keywords

Acetylcholine, central cholinergic system; Alzheimer's disease; Anaesthesia, general; Cognitive dysfunction; Complications, recovery

Indexed keywords

ACETYLCHOLINE; ANESTHETIC AGENT; APOLIPOPROTEIN E; ATRACURIUM; CISATRACURIUM; DESFLURANE; DONEPEZIL; FENTANYL; GALANTAMINE; ISOFLURANE; LAUDANOSINE; MORPHINE; MUSCARINIC RECEPTOR; NICOTINIC RECEPTOR; PROPOFOL; REMIFENTANIL; SEVOFLURANE; TACRINE; THIOPENTAL; TUBOCURARINE CHLORIDE;

ACETYLCHOLINE RELEASE; ALZHEIMER DISEASE; BRAIN FUNCTION; CELL LOSS; CHOLINERGIC NERVE CELL; CHOLINERGIC STIMULATION; CHOLINERGIC SYSTEM; CHOLINERGIC TRANSMISSION; COGNITIVE DEFECT; DELIRIUM; DRUG PREFERENCE; DRUG PROTEIN BINDING; DRUG SAFETY; GENERAL ANESTHESIA; HUMAN; MEMORY; MEMORY DISORDER; NONHUMAN; PAIN; POSTOPERATIVE PERIOD; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROGNOSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RECEPTOR BINDING; REVIEW; SYNAPTIC POTENTIAL; TISSUE DISTRIBUTION; UNCONSCIOUSNESS; VOLUNTARY MOVEMENT;

EID: 33748871295     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/ael233     Document Type: Review

References (60)

1. Aubert I, Araujo DM, Cecyre D, Robitaille Y, Gauthier S, Quirion R. Comparative alterations of nicotinic and muscarinic binding sites in Alzheimer's and Parkinson's diseases. J Neurochem 1992; 58: 529-41
2. Auld DS, Kornecook TJ, Bastianetto S, Quirion R. Alzheimer's disease and the basal forebrain cholinergic system: Relations to beta-amyloid peptides, cognition, and treatment strategies. Prog Neurobiol 2002; 68: 209-45
3. Bartus RT, Dean RL, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction. Science 1982; 217: 408-14
4. Belluardo N, Mudo G, Blum M, Fuxe K. Central nicotinic receptors, neurotrophic factors and neuroprotection. Behav Brain Res 2000; 113: 21-34
5. Blum S, Moore AN, Adams F, Dash PK. A mitogen-activated protein kinase cascade in the CA1/CA2 subfield of the dorsal hippocampus is essential for long-term spatial memory. J Neurosci 1999; 19: 3535-44
6. Bohnen NI, Kaufer DI, Hendrickson R, et al. Cognitive correlates of alterations in acetylcholinesterase in Alzheimer's disease. Neurosci Lett 2005; 380: 127-32
7. Bohnen NI, Warner M, Kokmen E, Beard CM, Kurland LT. Alzheimer's disease and cumulative exposure to anesthesia: A case-control study. J Am Geriatr Soc 1994; 42: 198-201
8. Bohnen N, Warner MA, Kokmen E, Kurland LT. Early and midlife exposure to anesthesia and age of onset of Alzheimer's disease. Int J Neurosci 1994; 77: 181-5
9. Bourin M, Ripoll N, Dailly E. Nicotinic receptors and Alzheimer's disease. Curr Med Res Opin 2003; 19: 169-77
10. Breteler MM, van Duijn CM, Chandra V, et al. Medical history and the risk of Alzheimer's disease: A collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group. Int J Epidemiol 1991; 20: S36-42
11. Chapman PF, Falinska AM, Knevett SG, Ramsay MF. Genes, models and Alzheimer's disease. Trends Genet 2001; 17: 254-61
12. Court JA, Martin-Ruiz C, Graham A, Perry E. Nicotinic receptors in human brain: Topography and pathology. J Chem Neuroanat 2000; 20: 281-98
13. Coyle JT, Price DL, DeLong MR. Alzheimer's disease: A disorder of cortical cholinergic innervation. Science 1983; 219: 1184-90
14. Diagnostic and Statistical Manual of Mental Disorders, 4th Edn. (DSM-IV R). Washington, DC: American Psychiatric Association, 1994
15. Dineley KT, Bell KA, Bui D, Sweatt JD. Beta-Amyloid peptide activates alpha7 anicotinic acetylcholine receptors expressed in Xenopus oocytes. J Biol Chem 2002; 277: 25056-61
16. Eckenhoff RG, Johansson JS, Wei H, et al. Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity. Anesthesiology 2004; 101: 703-9
17. Ehlert FJ, Tran LLP. Regional distribution of M1, M2 and non-M1, non-M2 subtypes of muscarinic binding sites in rat brain. J Pharmacol Exp Ther 1990; 255: 1148-57
18. Engelborghs S, Dermaut B, Goeman J, et al. Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects. J Neurol Neurosurg Psychiatry 2003; 74: 1148-51
19. Fernandez CR, Fields A, Richards T, Kaye AD. Anesthetic considerations in patients with Alzheimer's disease. J Clin Anesth 2003; 5: 52-8
20. Fodale V, Pratico C, Santamaria LB. Drugs of anesthesia, central nicotinic receptors and Parkinson's disease. Parkinsonism Relat Disord 2004; 10: 189-90
21. Fodale V, Santamaria LB. The inhibition of central nicotinic nAch receptors is the possible cause of prolonged cognitive impairment after anesthesia. Anesth Analg 2003; 97: 1207
22. Fodale V, Santamaria LB. Drugs of anesthesia, central nicotinic receptors and post-operative cognitive dysfunction. Acta Anaesthesiol Scand 2003; 47: 1180-1
23. Fox NC, Schott JM. Imaging cerebral atrophy: Normal ageing to Alzheimer's disease. Lancet 2004; 31: 392-4
24. Freye E, Levy JV. Use of opioids in the elderly - pharmacokinetic and pharmacodynamic considerations. Anasthesiol Intensivmed Notfallmed Schmerzther 2004; 39: 527-37
25. Ganguli M, Dodge HH, Shen C, Pandav RS, DeKosky ST. Alzheimer disease and mortality: A 15-year epidemiological study. Arch Neurol 2005; 62: 779-84
26. Gasparini M, Vanacore N, Schiaffini C, et al. A case-control study on Alzheimer's disease and exposure to anesthesia. Neurol Sci 2002; 23: 11-14
27. Gillardon F, Spranger M, Tiesler C, Hossmann KA. Expression of cell death-associated phospho-c-Jun and p53-activated gene 608 in hippocampal CA1 neurons following global ischemia. Brain Res Mol Brain Res 1999; 73: 138-43
28. Gopalakrishnan M, Monteggia LM, Anderson DJ, et al. Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor. J Pharmacol Exp Ther 1996; 276: 289-97
29. Graham AJ, Ray MA, Perry EK, et al. Differential nicotinic acetylcholine receptor subunit expression in the human hippocampus. J Chem Neuroanat 2003; 23: 97-113
30. Hartmann J, Erb C, Ebert U, et al. Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice. Neuroscience 2004; 125: 1009-17
31. Heishman SJ, Taylor RC, Henningfield JE. Nicotine and smoking: A review of effects on human performance. Exp Clin Psychopharmacol 1994; 2: 355-95
32. Ibebunjo C, Donati F, Fox GS, Eshelby D, Tchervenkov JI. The effects of chronic tacrine therapy on d-tubocurarine blockade in the soleus and tibialis muscles of the rat. Anesth Analg 1997; 85: 431-6
33. Lauder JM, Schambra UB. Morphogenetic roles of acetylcholine. Environ Health Perspect 1999; 107: 65-9
34. Lee VM. Abeta immunization: Moving Abeta peptide from brain to blood. Proc Natl Acad Sci USA 2001; 98: 8931-2
35. Levin ED, Damaj MJ, Glassco W, May EL, Martin BR. Bridged nicotine, isonicotine and norisonicotine effects on working memory performance of rats in the radial-arm maze. Drug Dev Res 1999; 46: 107-11
36. Levin ED, Toll K, Chang G. Epibatidine, a potent nicotinic agonist: effects on learning and memory in the radial-arm maze. Med Chem Res 1996; 6: 543-54
37. Ma J, Shen B, Stewart LS, Herrick IA, Leung LS. The septohippocampal system participates in general anesthesia. J Neurosci 2002; 22: RC200
38. Maloteaux JM. Clinical pharmacology and therapeutic aspects in certain degenerative neurological diseases. Bull Mem Acad R Med Belg 1996; 151: 429-32
39. Miyamoto E, Nakao S, Tomimoto H, et al. Ketamine attenuates hypocapnia-induced neuronal damage in the caudoputamen in a rat model of chronic cerebral hypoperfusion. Neurosci Lett 2004; 354: 26-9
40. Miyamoto E, Tomimoto H, Nakao S, et al. Caudoputamen is damaged by hypocapnia during mechanical ventilation in a rat model of chronic cerebral hypoperfusion. Stroke 2001; 32: 2920-5
41. Newhouse PA, Kelton M. Nicotinic systems in central nervous systems disease: Degenerative disorders and beyond. Pharm Acta Helv 2000; 74: 91-101
42. Ohm TG, Hamker U, Cedazo-Minguez A, et al. Apolipoprotein E and beta A4-amyloid: Signals and effects. Biochem Soc Symp 2001; 67: 121-9
43. Palotas M, Palotas A, Bjelik A, et al. Effect of general anesthetics on amyloid precursor protein and mRNA levels in the rat brain. Neurochem Res 2005; 30: 1021-6
44. Perry E, Walker M, Grace J, Perry R. Acetylcholine in mind: A neurotransmitter correlate of consciousness? Trends Neurosci 1999; 22: 273-80
45. Pratico C, Quattrone D, Lucanto T, Amato A, Penna O, Fodale V. Drugs of anesthesia acting on central cholinergic system may cause post-operative cognitive dysfunction and delirium. Med Hypotheses 2005; 65: 972-82
46. Prohovnik I, Mayeux R, Sackeim HA, Smith G, Stern Y, Alderson PO. Cerebral perfusion as a diagnostic marker of early Alzheimer's disease. Neurology 1988; 38: 931-7
47. Ravaglia G, Forti P, Maioli F, et al. Incidence and etiology of dementia in a large elderly Italian population. Neurology 2005; 64: 1525-30
48. Roses AD, Saunders AM. ApoE, Alzheimer's disease, and recovery from brain stress. Ann N Y Acad Sci 1997; 826: 200-12
49. Sadean MR, Glass PS. Pharmacokinetics in the elderly. Best Pract Res Clin Anaesthesiol 2003; 17: 191-205
50. Sanchez Morillo J, Demartini Ferrari A, Roca de Togores Lopez A. Interaction of donepezil and muscular blockers in Alzheimer's disease. Rev Esp Anestesiol Reanim 2003; 50: 97-100
51. Santos-Franco JA, Barquet-Platon EI, Mercado-Pimentel R, Ortiz-Velazquez RI, Cardona-Cabrera S, Otero-Siliceo E. Non-surgical potentially reversible dementias. Rev Neurol 2005; 40: 54-60
52. Schubert P, Ogata T, Marchini C, Ferroni S. Glia-related pathomechanisms in Alzheimer's disease: A therapeutic target? Mech Ageing Dev 2001; 123: 47-57
53. Selkoe DJ. Alzheimer's disease: Genes, proteins, and therapy. Physiol Rev 2001; 81: 741-66
54. Sramek JJ, Frackiewicz EJ, Cutler NR. Review of the acetylcholinesterase inhibitor galanthamine. Expert Opin Investig Drugs 2000; 9: 2393-402
55. Tassonyi E, Fathi M, Hughes J, et al. Cerebrospinal fluid concentrations of atracurium, laudanosine and vecuronium following clinical subarachnoid hemorrhage. Acta Anaesthesiol Scand 2002; 46: 1236-41
56. Tassonyi E, Charpantier E, Muller D, Dumont L, Bertrand D. The role of nicotinic acetylcholine receptors in the mechanisms of anesthesia. Brain Res Bull 2002; 57: 133-50
57. Tonner PH, Miller KW. Cholinergic receptors and anesthesia. Anasthesiol Intensivmed Notfallmed Schmerzther 1992; 27: 109-14
58. Yamashita M, Mori T, Nagata K, Yeh JZ, Narahashi T. Isoflurane modulation of neuronal nicotinic acetylcholine receptors expressed in human embryonic kidney cells. Anesthesiology 2005; 102: 76-84
59. van den Hoven MA, van Delden JJ. Ethical dilemmas in early detection of dementia. An inventory of moral intuitions in practice. Tijdschr Gerontol Geriatr 2002; 33: 9-14
60. Zoli M, Lena C, Picciotto MR, Changeux JP. Identification of four classes of brain nicotinic receptors using beta2 mutant mice. J Neurosci 1998; 18: 4461-72