-
1
-
-
19344375743
-
RNAi therapeutics: How likely, how soon?
-
Robinson,R. (2004) RNAi therapeutics: How likely, how soon? PLoS Biol., 2, 18-20.
-
(2004)
PLoS Biol
, vol.2
, pp. 18-20
-
-
Robinson, R.1
-
2
-
-
84882541518
-
-
Sudarsana,L.R., Sarojamma,V. and Ramakrishna,V. (2007) Future of RNAi in medicine: A review. World J. Med. Sci., 2, 1-14.
-
(2007)
Future of RNAi in Medicine: A Review. World J. Med. Sci
, vol.2
, pp. 1-14
-
-
Sudarsana, L.R.1
Sarojamma, V.2
Ramakrishna, V.3
-
3
-
-
4644223259
-
Mechanisms of gene silencing by double-stranded RNA
-
Meister,G. and Tuschl,T. (2004) Mechanisms of gene silencing by double-stranded RNA. Nature, 431, 343-349.
-
(2004)
Nature
, vol.431
, pp. 343-349
-
-
Meister, G.1
Tuschl, T.2
-
4
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
Hannon,G.J. and Rossi,J.J. (2004) Unlocking the potential of the human genome with RNA interference. Nature, 431, 371-378.
-
(2004)
Nature
, vol.431
, pp. 371-378
-
-
Hannon, G.J.1
Rossi, J.J.2
-
5
-
-
79960185923
-
Dicer recognizes the 5' end of RNA for efficient and accurate processing
-
Park,J.-E., Heo,I., Tian,Y., Simanshu,D.K., Chang,H., Jee,D., Patel,D.J. and Kim,V.N. (2011) Dicer recognizes the 5' end of RNA for efficient and accurate processing. Nature, 475, 201-205.
-
(2011)
Nature
, vol.475
, pp. 201-205
-
-
Park, J.-E.1
Heo, I.2
Tian, Y.3
Simanshu, D.K.4
Chang, H.5
Jee, D.6
Patel, D.J.7
Kim, V.N.8
-
6
-
-
3242736704
-
Human argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
-
Meister,G., Landthaler,M., Patkaniowska,A., Dorsett,Y., Teng,G. and Tuschl,T. (2004) Human argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell, 15, 185-197.
-
(2004)
Mol. Cell
, vol.15
, pp. 185-197
-
-
Meister, G.1
Landthaler, M.2
Patkaniowska, A.3
Dorsett, Y.4
Teng, G.5
Tuschl, T.6
-
7
-
-
34249810892
-
Argonaute proteins: Mediators of RNA silencing
-
Peters,L. and Meister,G. (2007) Argonaute proteins: Mediators of RNA silencing. Mol. Cell, 26, 611-623.
-
(2007)
Mol. Cell
, vol.26
, pp. 611-623
-
-
Peters, L.1
Meister, G.2
-
8
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu,J., Carmell,M.A., Rivas,F.V., Marsden,C.G., Thomson,J.M., Song,J.-J., Hammond,S.M., Joshua-Tor,L. and Hannon,G.J. (2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science (New York, NY), 305, 1437-1441.
-
(2004)
Science (New York, NY)
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Songj, J.6
Hammond, S.M.7
Joshua Tor, L.8
Hannon, G.J.9
-
9
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl,T., Zamore,P., Lehmann,R., Bartel,D. and Sharp,P. (1999) Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev., 13, 3191-3197.
-
(1999)
Genes Dev
, vol.13
, pp. 3191-3197
-
-
Tuschl, T.1
Zamore, P.2
Lehmann, R.3
Bartel, D.4
Sharp, P.5
-
10
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova,A., Reynolds,A. and Jayasena,S.D. (2003) Functional siRNAs and miRNAs exhibit strand bias. Cell, 115, 209-216.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
11
-
-
1642273831
-
An algorithm for selection of functional siRNA sequences
-
Amarzguioui,M. and Prydz,H. (2004) An algorithm for selection of functional siRNA sequences. Biochem. Biophys. Res. Commun., 316, 1050-1058.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.316
, pp. 1050-1058
-
-
Amarzguioui, M.1
Prydz, H.2
-
12
-
-
1642346273
-
Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference
-
Ui-Tei,K., Naito,Y., Takahashi,F., Haraguchi,T., Ohki-Hamazaki,H., Juni,A., Ueda,R. and Saigo,K. (2004) Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference. Nucleic Acids Res., 32, 936-948.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 936-948
-
-
Ui-Tei, K.1
Naito, Y.2
Takahashi, F.3
Haraguchi, T.4
Ohki-Hamazaki, H.5
Juni, A.6
Ueda, R.7
Saigo, K.8
-
13
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds,A., Leake,D., Boese,Q., Scaringe,S., Marshall,W.S. and Khvorova,A. (2004) Rational siRNA design for RNA interference. Nat. Biotech., 22, 326-330.
-
(2004)
Nat. Biotech
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
14
-
-
23444437819
-
Design of a genome-wide siRNA library using an artificial neural network
-
Huesken,D., Lange,J., Mickanin,C., Weiler,J., Asselbergs,F., Warner,J., Meloon,B., Engel,S., Rosenberg,A., Cohen,D. et al. (2005) Design of a genome-wide siRNA library using an artificial neural network. Nat. Biotech., 23, 995-1001.
-
(2005)
Nat. Biotech
, vol.23
, pp. 995-1001
-
-
Huesken, D.1
Lange, J.2
Mickanin, C.3
Weiler, J.4
Asselbergs, F.5
Warner, J.6
Meloon, B.7
Engel, S.8
Rosenberg, A.9
Cohen, D.10
-
15
-
-
33845663097
-
An accurate and interpretable model for siRNA efficacy prediction
-
Vert,J.-P., Foveau,N., Lajaunie,C. and Vandenbrouck,Y. (2006) An accurate and interpretable model for siRNA efficacy prediction. BMC Bioinformatics, 7, 520.
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 520
-
-
Vert, J.-P.1
Foveau, N.2
Lajaunie, C.3
Vandenbrouck, Y.4
-
16
-
-
33748701701
-
Computational models with thermodynamic and composition features improve siRNA design
-
Shabalina,S., Spiridonov,A. and Ogurtsov,A. (2006) Computational models with thermodynamic and composition features improve siRNA design. BMC Bioinformatics, 7, 65.
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 65
-
-
Shabalina, S.1
Spiridonov, A.2
Ogurtsov, A.3
-
17
-
-
35548980865
-
Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities
-
Ichihara,M., Murakumo,Y., Masuda,A., Matsuura,T., Asai,N., Jijiwa,M., Ishida,M., Shinmi,J., Yatsuya,H., Qiao,S. et al. (2007) Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities. Nucleic Acids Res., 35, e123.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Ichihara, M.1
Murakumo, Y.2
Masuda, A.3
Matsuura, T.4
Asai, N.5
Jijiwa, M.6
Ishida, M.7
Shinmi, J.8
Yatsuya, H.9
Qiao, S.10
-
18
-
-
34249772381
-
Fast folding and comparison of RNA secondary structures
-
Hofacker,I., Fontana,W., Stadler,P., Bonhoeffer,L.S., Tacker,M. and Schuster,P. (1994) Fast folding and comparison of RNA secondary structures. Monatsh. Chem., 125, 167-188.
-
(1994)
Monatsh. Chem
, vol.125
, pp. 167-188
-
-
Hofacker, I.1
Fontana, W.2
Stadler, P.3
Bonhoeffer, L.S.4
Tacker, M.5
Schuster, P.6
-
19
-
-
39149106448
-
Efficient siRNA selection using hybridization thermodynamics
-
Lu,Z.J. and Mathews,D.H. (2008) Efficient siRNA selection using hybridization thermodynamics. Nucleic Acids Res., 36, 640-647.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 640-647
-
-
Lu, Z.J.1
Mathews, D.H.2
-
20
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
Zuker,M. (2003) Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res., 31, 3406-3415.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
-
21
-
-
56249145105
-
Structure of the guide-strand-containing argonaute silencing complex
-
Wang,Y., Sheng,G., Juranek,S., Tuschl,T. and Patel,D.J. (2008) Structure of the guide-strand-containing argonaute silencing complex. Nature, 456, 209-213.
-
(2008)
Nature
, vol.456
, pp. 209-213
-
-
Wang, Y.1
Sheng, G.2
Juranek, S.3
Tuschl, T.4
Patel, D.J.5
-
22
-
-
0027215340
-
-
Wold,S., Jonsson,J., Sjiistriim,M., Sandberg,M. and Rannar,S. (1993) DNA and peptide sequences and chemical processes multivariately modelled by principal component analysis and partial least-squares projections to latent structures. Anal. Chim. Acta, 217, 239-253.
-
(1993)
DNA and Peptide Sequences and Chemical Processes Multivariately Modelled by Principal Component Analysis and Partial Least-squares Projections to Latent Structures. Anal. Chim. Acta
, vol.217
, pp. 239-253
-
-
Wold, S.1
Jonsson, J.2
Sjiistriim, M.3
Sandberg, M.4
Rannar, S.5
-
23
-
-
77957350921
-
Toward a consensus view of duplex RNA flexibility
-
Faustino,I., Perez,A. and Orozco,M. (2010) Toward a consensus view of duplex RNA flexibility. Biophys. J., 99, 1876-1885.
-
(2010)
Biophys. J.
, vol.99
, pp. 1876-1885
-
-
Faustino, I.1
Perez, A.2
Orozco, M.3
-
24
-
-
1542709582
-
MRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity
-
Huesken,D., Asselbergs,F., Kinzel,B., Natt,F., Weiler,J., Martin,P., Haner,R. and Hall,J. (2003) mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity. Nucleic Acids Res., 31, e102.
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Huesken, D.1
Asselbergs, F.2
Kinzel, B.3
Natt, F.4
Weiler, J.5
Martin, P.6
Haner, R.7
Hall, J.8
-
25
-
-
0037470145
-
Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis
-
Vickers,T.A., Koo,S., Bennett,C.F., Crooke,S.T., Dean,N.M. and Baker,B.F. (2003) Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis. J. Biol. Chem., 278, 7108-7118.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 7108-7118
-
-
Vickers, T.A.1
Koo, S.2
Bennett, C.F.3
Crooke, S.T.4
Dean, N.M.5
Baker, B.F.6
-
26
-
-
24344500241
-
Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing
-
Harborth,J., Elbashir,S.M., Vandenburgh,K., Manninga,H., Scaringe,S.A., Weber,K. and Tuschl,T. (2003) Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing. Antisense Nucleic Acid Drug Dev., 13, 83-105.
-
(2003)
Antisense Nucleic Acid Drug Dev
, vol.13
, pp. 83-105
-
-
Harborth, J.1
Elbashir, S.M.2
Vandenburgh, K.3
Manninga, H.4
Scaringe, S.A.5
Weber, K.6
Tuschl, T.7
-
27
-
-
0029151591
-
Synthesis, deprotection, analysis and purification of RNA and ribosomes
-
Wincott,F., DiRenzo,A., Shaffer,C., Grimm,S., Tracz,D., Workman,C., Sweedler,D., Gonzalez,C., Scaringe,S. and Usman,N. (1995) Synthesis, deprotection, analysis and purification of RNA and ribosomes. Nucleic Acids Res., 23, 2677-2684.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 2677-2684
-
-
Wincott, F.1
Direnzo, A.2
Shaffer, C.3
Grimm, S.4
Tracz, D.5
Workman, C.6
Sweedler, D.7
Gonzalez, C.8
Scaringe, S.9
Usman, N.10
-
28
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz,D.S., Hutvagner,G., Du,T., Xu,Z., Aronin,N. and Zamore,P.D. (2003) Asymmetry in the assembly of the RNAi enzyme complex. Cell, 115, 199-208.
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
29
-
-
0032552882
-
Thermodynamic parameters for an expanded nearest-neighbor model for ormation of RNA duplexes with Watson-Crick base Pairs
-
Xia,T., SantaLucia,J., Burkard,M.E., Kierzek,R., Schroeder,S.J., Jiao,X., Cox,C. and Turner,D.H. (1998) Thermodynamic parameters for an expanded nearest-neighbor model for ormation of RNA duplexes with Watson-Crick base Pairs. Biochemistry, 37, 14719-14735.
-
(1998)
Biochemistry
, vol.37
, pp. 14719-14735
-
-
Xia, T.1
Santalucia, J.2
Burkard, M.E.3
Kierzek, R.4
Schroeder, S.J.5
Jiao, X.6
Cox, C.7
Turner, D.H.8
-
30
-
-
0029011701
-
A second generation force field for the simulation of proteins
-
Cornell,W.D., Cieplak,P., Bayly,C.I., Gould,I.R., Merz,K.M., Ferguson,D.M., Spellmeyer,D.C., Fox,T., Caldwell,J.W. and Kollman,P.A. (1995) A second generation force field for the simulation of proteins, nucleic acids, and organic molecules. J. Am. Chem. Soc., 117, 5179-5197.
-
(1995)
Nucleic Acids, and Organic Molecules. J. Am. Chem. Soc
, vol.117
, pp. 5179-5197
-
-
Cornell, W.D.1
Cieplak, P.2
Bayly, C.I.3
Gould, I.R.4
Merz, K.M.5
Ferguson, D.M.6
Spellmeyer, D.C.7
Fox, T.8
Caldwell, J.W.9
Kollman, P.A.10
-
31
-
-
34250318638
-
Refinement of the AMBER force field for nucleic acids: Improving the description of alpha/ gamma conformers
-
Perez,A., Marchan,I., Svozil,D., Sponer,J., Cheatham,T.E. III, Laughton,C.A. and Orozco,M. (2007) Refinement of the AMBER force field for nucleic acids: Improving the description of alpha/ gamma conformers. Biophys. J., 92, 3817-3829.
-
(2007)
Biophys. J.
, vol.92
, pp. 3817-3829
-
-
Perez, A.1
Marchan, I.2
Svozil, D.3
Sponer, J.4
Cheathamiii, T.E.5
Laughton, C.A.6
Orozco, M.7
-
32
-
-
33645393530
-
Exploring the essential dynamics of B-DNA
-
Perez,A., Blas,J.R., Rueda,M., Lopez-Bes,J.M., de la Cruz,X. and Orozco,M. (2005) Exploring the essential dynamics of B-DNA. J. Chem. Theory Comput., 1, 790-800.
-
(2005)
J. Chem. Theory Comput
, vol.1
, pp. 790-800
-
-
Perez, A.1
Blas, J.R.2
Rueda, M.3
Lopez-Bes, J.M.4
De La Cruz, X.5
Orozco, M.6
-
33
-
-
36749098380
-
Dynamics of B-DNA on the microsecond time scale
-
Perez,A., Luque,F.J. and Orozco,M. (2007) Dynamics of B-DNA on the microsecond time scale. J. Am. Chem. Soc., 129, 14739-14745.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 14739-14745
-
-
Perez, A.1
Luque, F.J.2
Orozco, M.3
-
34
-
-
70450261721
-
Conformational analysis of nucleic acids revisited: Curves+
-
Lavery,R., Moakher,M., Maddocks,J.H., Petkeviciute,D. and Zakrzewska,K. (2009) Conformational analysis of nucleic acids revisited: Curves+. Nucleic Acids Res., 37, 5917-5929.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 5917-5929
-
-
Lavery, R.1
Moakher, M.2
Maddocks, J.H.3
Petkeviciute, D.4
Zakrzewska, K.5
-
35
-
-
0033618122
-
Molecular dynamics studies of DNA A-tract structure and flexibility
-
Sherer,E.C., Harris,S.A., Soliva,R., Orozco,M. and Laughton,C.A. (1999) Molecular dynamics studies of DNA A-tract structure and flexibility. J. Am. Chem. Soc., 121, 5981-5991.
-
(1999)
J. Am. Chem. Soc
, vol.121
, pp. 5981-5991
-
-
Sherer, E.C.1
Harris, S.A.2
Soliva, R.3
Orozco, M.4
Laughton, C.A.5
-
36
-
-
0034682870
-
A-tract bending: Insights into experimental structures by computational models
-
Strahs,D. and Schlick,T. (2000) A-tract bending: Insights into experimental structures by computational models. J. Mol. Biol., 301, 643-663.
-
(2000)
J. Mol. Biol
, vol.301
, pp. 643-663
-
-
Strahs, D.1
Schlick, T.2
-
37
-
-
0042161890
-
The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides
-
Kretschmer-Kazemi Far,R. and Sczakiel,G. (2003) The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides. Nucleic Acids Res., 31, 4417-4424.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 4417-4424
-
-
Kretschmer-Kazemi Far, R.1
Sczakiel, G.2
-
38
-
-
27944473306
-
Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency
-
Patzel,V., Rutz,S., Dietrich,I., Koberle,C., Scheffold,A. and Kaufmann,S.H.E. (2005) Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency. Nat. Biotech., 23, 1440-1444.
-
(2005)
Nat. Biotech
, vol.23
, pp. 1440-1444
-
-
Patzel, V.1
Rutz, S.2
Dietrich, I.3
Koberle, C.4
Scheffold, A.5
Kaufmann, S.H.E.6
-
39
-
-
33746907851
-
SiRNA efficiency: Structure or sequence-that is the question
-
doi: 10.1155/JBB/ 2006/83757
-
Kurreck,J. (2006) siRNA efficiency: Structure or sequence - that is the question. J. Biomed. Biotechnol., 2006, 1-7; doi: 10.1155/JBB/ 2006/83757.
-
(2006)
J. Biomed. Biotechnol
, vol.2006
, pp. 1-7
-
-
Kurreck, J.1
-
40
-
-
26444437334
-
SiRNA target site secondary structure predictions using local stable substructures
-
Heale,B.S.E., Soifer,H.S., Bowers,C. and Rossi,J.J. (2005) siRNA target site secondary structure predictions using local stable substructures. Nucleic Acids Res., 33, e30.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Heale, B.S.E.1
Soifer, H.S.2
Bowers, C.3
Rossi, J.J.4
-
41
-
-
43249105382
-
Impact of target mRNA structure on siRNA silencing efficiency: A large-scale study
-
Gredell,J.A., Berger,A.K. and Walton,S.P. (2008) Impact of target mRNA structure on siRNA silencing efficiency: A large-scale study. Biotechnol. Bioeng., 100, 744-755.
-
(2008)
Biotechnol. Bioeng
, vol.100
, pp. 744-755
-
-
Gredell, J.A.1
Berger, A.K.2
Walton, S.P.3
-
42
-
-
43449124403
-
The impact of target site accessibility on the design of effective iRNAs
-
Tafer,H., Ameres,S.L., Obernosterer,G., Gebeshuber,C.A., Schroeder,R., Martinez,J. and Hofacker,I.L. (2008) The impact of target site accessibility on the design of effective iRNAs. Nat. Biotech., 26, 578-583.
-
(2008)
Nat. Biotech
, vol.26
, pp. 578-583
-
-
Tafer, H.1
Ameres, S.L.2
Obernosterer, G.3
Gebeshuber, C.A.4
Schroeder, R.5
Martinez, J.6
Hofacker, I.L.7
-
43
-
-
9944247186
-
Using chemometrics for navigating in the large data sets of genomics, proteomics, and metabonomics (gpm
-
Eriksson,L., Antti,H., Gottfries,J., Holmes,E., Johansson,E., Lindgren,F., Long,I., Lundstedt,T., Trygg,J. and Wold,S. (2004) Using chemometrics for navigating in the large data sets of genomics, proteomics, and metabonomics (gpm). Anal. Bioanal. Chem., 380, 419-429.
-
(2004)
Anal. Bioanal. Chem
, vol.380
, pp. 419-429
-
-
Eriksson, L.1
Antti, H.2
Gottfries, J.3
Holmes, E.4
Johansson, E.5
Lindgren, F.6
Long, I.7
Lundstedt, T.8
Trygg, J.9
Wold, S.10
-
44
-
-
33846829987
-
The pls package: Principal component and partial least squares regression in R
-
Mevik,B.-H. and Wehrens,R. (2007) The pls package: principal component and partial least squares regression in R. J. Stat. Softw., 18.
-
(2007)
J. Stat. Softw
, vol.18
-
-
Mevik, B.-H.1
Wehrens, R.2
-
46
-
-
84873664393
-
Information science and statistics
-
Jordan,M., Nowak,R. and Scho lkopf,B. (eds Springer, Germany
-
Vapnik,V. (2000) Information science and statistics. In: Jordan,M., Nowak,R. and Scholkopf,B. (eds), The Nature of Statistical Learning Theory, Vol. 19. Springer, Germany, p. 48.
-
(2000)
Nature of Statistical Learning Theory
, vol.19
, pp. 48
-
-
Vapnik, V.1
-
48
-
-
0035478854
-
Random forests
-
Breiman,L. (2001) Random forests. Mach. Learn., 45, 5-32.
-
(2001)
Mach. Learn
, vol.45
, pp. 5-32
-
-
Breiman, L.1
-
49
-
-
0027310371
-
Generating optimal linear PLS estimations (GOLPE): An advanced chemometric tool for handling 3D-QSAR problems
-
Baroni,M., Costantino,G., Cruciani,G., Riganelli,D., Valigi,R. and Clementi,S. (1993) Generating optimal linear PLS estimations (GOLPE): An advanced chemometric tool for handling 3D-QSAR problems. Quant. Struct. Act. Relat., 12, 9-20.
-
(1993)
Quant. Struct. Act. Relat
, vol.12
, pp. 9-20
-
-
Baroni, M.1
Costantino, G.2
Cruciani, G.3
Riganelli, D.4
Valigi, R.5
Clementi, S.6
-
50
-
-
34547218463
-
Insights into effective RNAi gained from large-scale siRNA validation screening
-
Krueger,U., Bergauer,T., Kaufmann,B., Wolter,I., Pilk,S., Heider-Fabian,M., Kirch,S., Artz-Oppitz,C., Isselhorst,M. and Konrad,J. (2007) Insights into effective RNAi gained from large-scale siRNA validation screening. Oligonucleotides, 17, 237-250.
-
(2007)
Oligonucleotides
, vol.17
, pp. 237-250
-
-
Krueger, U.1
Bergauer, T.2
Kaufmann, B.3
Wolter, I.4
Pilk, S.5
Heider-Fabian, M.6
Kirch, S.7
Artz-Oppitz, C.8
Isselhorst, M.9
Konrad, J.10
-
51
-
-
78449310037
-
MRNA turnover rate limits siRNA and microRNA efficacy
-
Larsson,E., Sander,C. and Marks,D. (2010) mRNA turnover rate limits siRNA and microRNA efficacy. Mol. Syst. Biol., 6, 433.
-
(2010)
Mol. Syst. Biol
, vol.6
, pp. 433
-
-
Larsson, E.1
Sander, C.2
Marks, D.3
-
52
-
-
22844448088
-
Functional polarity is introduced by Dicer processing of short substrate RNAs
-
Rose,S.D., Kim,D.-H., Amarzguioui,M., Heidel,J.D., Collingwood,M.A., Davis,M.E., Rossi,J.J. and Behlke,M.A. (2005) Functional polarity is introduced by Dicer processing of short substrate RNAs. Nucleic Acids Res., 33, 4140-4156.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4140-4156
-
-
Rose, S.D.1
Kim, D.-H.2
Amarzguioui, M.3
Heidel, J.D.4
Collingwood, M.A.5
Davis, M.E.6
Rossi, J.J.7
Behlke, M.A.8
-
53
-
-
0023517027
-
Rapid cytoplasmic turnover of c-myc mRNA: Requirement of the 30 untranslated sequences
-
Jones,T.R. and Cole,M.D. (1987) Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 30 untranslated sequences. Mol. Cell. Biol., 7, 4513-4521.
-
(1987)
Mol. Cell. Biol
, vol.7
, pp. 4513-4521
-
-
Jones, T.R.1
Cole, M.D.2
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