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Volumn 127, Issue 11, 2007, Pages 2656-2667

A role for TGF-β1-induced cellular responses during wound healing of the non-scarring early human fetus?

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; MESSENGER RNA; MITOGENIC AGENT; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 35348839573     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700951     Document Type: Article
Times cited : (73)

References (58)
  • 1
    • 85047692249 scopus 로고    scopus 로고
    • Impaired Smad7-Smurf mediated negative regulation of TGF-β signaling in scleroderma fibroblasts
    • Asano Y, Ihn H, Yamane K, Kubo M, Tamaki K (2004) Impaired Smad7-Smurf mediated negative regulation of TGF-β signaling in scleroderma fibroblasts. J Clin Invest 113:253-64
    • (2004) J Clin Invest , vol.113 , pp. 253-264
    • Asano, Y.1    Ihn, H.2    Yamane, K.3    Kubo, M.4    Tamaki, K.5
  • 3
    • 0036210318 scopus 로고    scopus 로고
    • Review of current progress in the structure and function of Smad proteins
    • Chen W, Fu XB, Sheng ZY (2002) Review of current progress in the structure and function of Smad proteins. Chin Med J (Eng) 115:446-50
    • (2002) Chin Med J (Eng) , vol.115 , pp. 446-450
    • Chen, W.1    Fu, X.B.2    Sheng, Z.Y.3
  • 4
    • 0000432767 scopus 로고    scopus 로고
    • Transforming growth factor β1 rescues serum deprivation-induced apoptosis via the mitogen activated protein kinase (MAPK) pathway in macrophages
    • Chin BY, Petrache I, Choi AMK, Choi ME (1999) Transforming growth factor β1 rescues serum deprivation-induced apoptosis via the mitogen activated protein kinase (MAPK) pathway in macrophages. J Biol Chem 274:11362-8
    • (1999) J Biol Chem , vol.274 , pp. 11362-11368
    • Chin, B.Y.1    Petrache, I.2    Choi, A.M.K.3    Choi, M.E.4
  • 6
    • 0034878046 scopus 로고    scopus 로고
    • Expression of TGF-beta and its receptors in murine fetal and adult dermal wounds
    • Cowin AJ, Holmes TM, Brosnan P, Fergurson MWJ (2001) Expression of TGF-beta and its receptors in murine fetal and adult dermal wounds. Eur J Dermatol 11:424-31
    • (2001) Eur J Dermatol , vol.11 , pp. 424-431
    • Cowin, A.J.1    Holmes, T.M.2    Brosnan, P.3    Fergurson, M.W.J.4
  • 8
    • 0032924764 scopus 로고    scopus 로고
    • Inhibition of rat hepatocyte proliferation by transforming growth factor beta and glucogon is associated with inhibition of ERK2 and p70 S6 kinase
    • Dixon M, Agius L, Yeaman SJ, Day CP (1999) Inhibition of rat hepatocyte proliferation by transforming growth factor beta and glucogon is associated with inhibition of ERK2 and p70 S6 kinase. Hepatology 29:1418-24
    • (1999) Hepatology , vol.29 , pp. 1418-1424
    • Dixon, M.1    Agius, L.2    Yeaman, S.J.3    Day, C.P.4
  • 9
    • 0032967436 scopus 로고    scopus 로고
    • Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-β1 and TGF-β3
    • Eickelberg O, Kohler E, Reichenberger F, Bertschin S, Woodtli T, Erne P et al. (1999) Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-β1 and TGF-β3. Am J Physiol 276:L814-7
    • (1999) Am J Physiol , vol.276
    • Eickelberg, O.1    Kohler, E.2    Reichenberger, F.3    Bertschin, S.4    Woodtli, T.5    Erne, P.6
  • 10
    • 0033601179 scopus 로고    scopus 로고
    • Interdependent SMAD and JNK signaling in transforming growth factor-β-mediated transcription
    • Engel ME, McDonnell MA, Law BK, Moses HL (1999) Interdependent SMAD and JNK signaling in transforming growth factor-β-mediated transcription. J Biol Chem 274:37413-20
    • (1999) J Biol Chem , vol.274 , pp. 37413-37420
    • Engel, M.E.1    McDonnell, M.A.2    Law, B.K.3    Moses, H.L.4
  • 12
    • 0037437371 scopus 로고    scopus 로고
    • TGF-β1-mediated fibroblast-myofibroblast terminal differentiation-the role of Smad proteins
    • Evans RA, Tian YC, Steadman R, Phillips AO (2003) TGF-β1-mediated fibroblast-myofibroblast terminal differentiation-the role of Smad proteins. Exp Cell Res 282:90-100
    • (2003) Exp Cell Res , vol.282 , pp. 90-100
    • Evans, R.A.1    Tian, Y.C.2    Steadman, R.3    Phillips, A.O.4
  • 13
    • 0029875396 scopus 로고    scopus 로고
    • Transforming growth factors β1, β2, and β3 and their receptors are differentially regulated during normal and impaired wound healing
    • Frank S, Madlener M, Werner S (1996) Transforming growth factors β1, β2, and β3 and their receptors are differentially regulated during normal and impaired wound healing. J Biol Chem 271:10188-93
    • (1996) J Biol Chem , vol.271 , pp. 10188-10193
    • Frank, S.1    Madlener, M.2    Werner, S.3
  • 14
    • 0036829567 scopus 로고    scopus 로고
    • Modulation of Smad2-mediated signaling by extracellular signal regulated kinase
    • Funaba M, Zimmerman CM, Mathews LS (2002) Modulation of Smad2-mediated signaling by extracellular signal regulated kinase. J Biol Chem 277:41361-8
    • (2002) J Biol Chem , vol.277 , pp. 41361-41368
    • Funaba, M.1    Zimmerman, C.M.2    Mathews, L.S.3
  • 15
    • 0028937610 scopus 로고
    • Transforming growth factor beta activation of p44 MAPK in proliferating cultures of epithelial cells
    • Hartsough MT, Mulder KM (1995) Transforming growth factor beta activation of p44 MAPK in proliferating cultures of epithelial cells. J Biol Chem 270:7117-24
    • (1995) J Biol Chem , vol.270 , pp. 7117-7124
    • Hartsough, M.T.1    Mulder, K.M.2
  • 17
    • 0033104505 scopus 로고    scopus 로고
    • TGF-β induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway
    • Hocevar BA, Brown TL, Howe PH (1999) TGF-β induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J 18:1345-56
    • (1999) EMBO J , vol.18 , pp. 1345-1356
    • Hocevar, B.A.1    Brown, T.L.2    Howe, P.H.3
  • 18
    • 0028149665 scopus 로고
    • Transforming growth factor beta 2 stimulates active and chronic activation of the mitogen-activated protein kinase cascade in rat renal mesangial cells
    • Huwiler A, Pfeilschifter J (1994) Transforming growth factor beta 2 stimulates active and chronic activation of the mitogen-activated protein kinase cascade in rat renal mesangial cells. FEBS Lett 354:255-8
    • (1994) FEBS Lett , vol.354 , pp. 255-258
    • Huwiler, A.1    Pfeilschifter, J.2
  • 19
    • 35348849629 scopus 로고
    • Ontogenetic transition of wound healing pattern in rat skin occurring at the fetal stage
    • Ihara S, Motobayashi Y, Nagao E, Kistler A (1990) Ontogenetic transition of wound healing pattern in rat skin occurring at the fetal stage. Development 114:253-9
    • (1990) Development , vol.114 , pp. 253-259
    • Ihara, S.1    Motobayashi, Y.2    Nagao, E.3    Kistler, A.4
  • 20
    • 0036670339 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of Smads 2,3, and 4 permits sensing of TGF-β receptor activity
    • Inman GJ, Nicolás FJ, Hill CS (2002) Nucleocytoplasmic shuttling of Smads 2,3, and 4 permits sensing of TGF-β receptor activity. Mol Cell 10:283-94
    • (2002) Mol Cell , vol.10 , pp. 283-294
    • Inman, G.J.1    Nicolás, F.J.2    Hill, C.S.3
  • 21
    • 0042090278 scopus 로고    scopus 로고
    • Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing
    • Javelaud D, Laboureau J, Gabison E, Verrecchia F, Mauviel A (2003) Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing. J Biol Chem 278:24624-8
    • (2003) J Biol Chem , vol.278 , pp. 24624-24628
    • Javelaud, D.1    Laboureau, J.2    Gabison, E.3    Verrecchia, F.4    Mauviel, A.5
  • 22
    • 0028806184 scopus 로고
    • Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction
    • Kaartinen V, Voncken JW, Schuler C, Warburton D, Bu D, Heisterkamp N et al. (1995) Abnormal lung development and cleft palate in mice lacking TGF-β3 indicates defects of epithelial-mesenchymal interaction. Nat Genet 11:415-21
    • (1995) Nat Genet , vol.11 , pp. 415-421
    • Kaartinen, V.1    Voncken, J.W.2    Schuler, C.3    Warburton, D.4    Bu, D.5    Heisterkamp, N.6
  • 23
    • 2142646426 scopus 로고    scopus 로고
    • TGF-β signaling and the fibrotic response
    • Leask A, Abraham DJ (2004) TGF-β signaling and the fibrotic response. FASEB J 18:816-27
    • (2004) FASEB J , vol.18 , pp. 816-827
    • Leask, A.1    Abraham, D.J.2
  • 24
    • 0027743449 scopus 로고
    • Spatial and temporal patterns of immunoreactive transforming growth factor β1, β2, and β3 during excisional wound repair
    • Levine JH, Moses HL, Gold LI, Nanney LB (1993) Spatial and temporal patterns of immunoreactive transforming growth factor β1, β2, and β3 during excisional wound repair. Am J Pathol 143:368-80
    • (1993) Am J Pathol , vol.143 , pp. 368-380
    • Levine, J.H.1    Moses, H.L.2    Gold, L.I.3    Nanney, L.B.4
  • 27
    • 0035117104 scopus 로고    scopus 로고
    • Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signalling
    • Luukko K, Ylikorkala A, Mäkelä TP (2001) Developmentally regulated expression of Smad3, Smad4, Smad6, and Smad7 involved in TGF-beta signalling. Mech Dev 101:209-12
    • (2001) Mech Dev , vol.101 , pp. 209-212
    • Luukko, K.1    Ylikorkala, A.2    Mäkelä, T.P.3
  • 28
    • 0027275277 scopus 로고
    • Rapid induction and clearance of TGFβ1 is an early response to wounding in the mouse embryo
    • Martin P, Dickson MC, Millan FA, Akhurst RJ (1993) Rapid induction and clearance of TGFβ1 is an early response to wounding in the mouse embryo. Dev Genet 14:225-38
    • (1993) Dev Genet , vol.14 , pp. 225-238
    • Martin, P.1    Dickson, M.C.2    Millan, F.A.3    Akhurst, R.J.4
  • 29
    • 0034678908 scopus 로고    scopus 로고
    • Transcriptional control by the TGFβ/Smad signaling system
    • Massague J, Wotton D (2000) Transcriptional control by the TGFβ/Smad signaling system. EMBO J 19:1745-54
    • (2000) EMBO J , vol.19 , pp. 1745-1754
    • Massague, J.1    Wotton, D.2
  • 30
    • 0029090422 scopus 로고
    • Analysis of tissue movements of embryonic wound healing-DiI studies in the limb bud stage mouse embryos
    • McCluskey J, Martin P (1995) Analysis of tissue movements of embryonic wound healing-DiI studies in the limb bud stage mouse embryos. Dev Biol 170:102-14
    • (1995) Dev Biol , vol.170 , pp. 102-114
    • McCluskey, J.1    Martin, P.2
  • 32
    • 0034255634 scopus 로고    scopus 로고
    • Modulation of endogenous Smad expression in normal skin fibroblasts by Transforming growth factor-β
    • Mori Y, Chen S-J, Varga J (2000) Modulation of endogenous Smad expression in normal skin fibroblasts by Transforming growth factor-β. Exp Cell Res 258:374-83
    • (2000) Exp Cell Res , vol.258 , pp. 374-383
    • Mori, Y.1    Chen, S.-J.2    Varga, J.3
  • 33
    • 10444259759 scopus 로고    scopus 로고
    • Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor β responses in skin fibroblasts
    • Mori Y, Ishida W, Bhattacharyya S, Li Y, Platanias LC, Varga J (2004) Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor β responses in skin fibroblasts. Arthritis Rheum 50:4008-21
    • (2004) Arthritis Rheum , vol.50 , pp. 4008-4021
    • Mori, Y.1    Ishida, W.2    Bhattacharyya, S.3    Li, Y.4    Platanias, L.C.5    Varga, J.6
  • 34
    • 0036714333 scopus 로고    scopus 로고
    • Smad signaling network
    • Moustakas A (2002) Smad signaling network. J Cell Sci 115:3355-6
    • (2002) J Cell Sci , vol.115 , pp. 3355-3356
    • Moustakas, A.1
  • 35
  • 36
    • 0029893734 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase and the small GTP-binding protein, Rac, contribute to the effects of transforming growth factor-β1 on gene expression
    • Musci I, Skorecki KL, Goldberg HJ (1996) Extracellular signal-regulated kinase and the small GTP-binding protein, Rac, contribute to the effects of transforming growth factor-β1 on gene expression. J Biol Chem 271:16567-72
    • (1996) J Biol Chem , vol.271 , pp. 16567-16572
    • Musci, I.1    Skorecki, K.L.2    Goldberg, H.J.3
  • 38
    • 0038548187 scopus 로고    scopus 로고
    • Attenuation of the TGF-β-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-β-induced growth arrest
    • Nicolás FJ, Hill CS (2003) Attenuation of the TGF-β-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-β-induced growth arrest. Oncogene 22:3698-711
    • (2003) Oncogene , vol.22 , pp. 3698-3711
    • Nicolás, F.J.1    Hill, C.S.2
  • 39
    • 0024534977 scopus 로고
    • Independent regulation of collagenase, 72kDa progelatinase, and metalloproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta
    • Overall CM, Wrana JL, Sodek J (1989) Independent regulation of collagenase, 72kDa progelatinase, and metalloproteinase inhibitor expression in human fibroblasts by transforming growth factor-beta. J Biol Chem 264:1860-9
    • (1989) J Biol Chem , vol.264 , pp. 1860-1869
    • Overall, C.M.1    Wrana, J.L.2    Sodek, J.3
  • 40
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • Pfaffl MW, Horgan GW, Dempfle L (2002) Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30:e36
    • (2002) Nucleic Acids Res , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 41
    • 3042735167 scopus 로고    scopus 로고
    • Differential proliferative response of fetal and adult human skin fibroblasts to transforming growth factor-β
    • Pratsinis H, Giannouli CC, Zervolea I, Psarras S, Stathakos D, Kletsas D (2004) Differential proliferative response of fetal and adult human skin fibroblasts to transforming growth factor-β. Wound Repair Regen 12:374-83
    • (2004) Wound Repair Regen , vol.12 , pp. 374-383
    • Pratsinis, H.1    Giannouli, C.C.2    Zervolea, I.3    Psarras, S.4    Stathakos, D.5    Kletsas, D.6
  • 42
    • 0034602286 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase 1/2 inhibits type I collagen expression by human skin fibroblasts
    • Reunanen N, Foschi M, Han J, Kähäri VM (2000) Activation of extracellular signal-regulated kinase 1/2 inhibits type I collagen expression by human skin fibroblasts. J Biol Chem 275:34634-9
    • (2000) J Biol Chem , vol.275 , pp. 34634-34639
    • Reunanen, N.1    Foschi, M.2    Han, J.3    Kähäri, V.M.4
  • 43
    • 0018357624 scopus 로고
    • Intrauterine wound healing in a 20 week human fetus
    • Rowlatt U (1979) Intrauterine wound healing in a 20 week human fetus. Virchows Arch A Pathol Anat Histol 381:353-61
    • (1979) Virchows Arch A Pathol Anat Histol , vol.381 , pp. 353-361
    • Rowlatt, U.1
  • 44
    • 0030609894 scopus 로고    scopus 로고
    • TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes
    • Sanford LP, Ormsby I, Gittenberger-de Groot AC, Sariola H, Friedman R, Boivin GP et al. (1997) TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes. Development 124:2659-70
    • (1997) Development , vol.124 , pp. 2659-2670
    • Sanford, L.P.1    Ormsby, I.2    Gittenberger-de Groot, A.C.3    Sariola, H.4    Friedman, R.5    Boivin, G.P.6
  • 45
    • 0031828004 scopus 로고    scopus 로고
    • The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-β1
    • Serini G, Bochaton-Piallat M, Ropraz P, Geinoz A, Borsi L, Zardi L et al. (1998) The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-β1. J Cell Biol 142:873-81
    • (1998) J Cell Biol , vol.142 , pp. 873-881
    • Serini, G.1    Bochaton-Piallat, M.2    Ropraz, P.3    Geinoz, A.4    Borsi, L.5    Zardi, L.6
  • 46
    • 0026505458 scopus 로고
    • Control of scarring in adult wounds by neutralising antibody to transforming growth factor β
    • Shah M, Foreman DM, Fergurson MW (1992) Control of scarring in adult wounds by neutralising antibody to transforming growth factor β. Lancet 339:213-4
    • (1992) Lancet , vol.339 , pp. 213-214
    • Shah, M.1    Foreman, D.M.2    Fergurson, M.W.3
  • 48
    • 0028986030 scopus 로고
    • Neutralization of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring
    • Shah M, Foreman DM, Fergurson MW (1995) Neutralization of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring. J Cell Sci 108:985-1002
    • (1995) J Cell Sci , vol.108 , pp. 985-1002
    • Shah, M.1    Foreman, D.M.2    Fergurson, M.W.3
  • 49
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease
    • Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M et al. (1992) Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 359:693-9
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1    Ormsby, I.2    Kier, A.B.3    Pawlowski, S.4    Diebold, R.J.5    Yin, M.6
  • 50
    • 10744219901 scopus 로고    scopus 로고
    • Ontogenetic transition in fetal wound transforming growth factor-β regulation correlates with collagen organization
    • Soo C, Beanes SR, Hu F-Y, Zhang X, Dang C, Chang G et al. (2003) Ontogenetic transition in fetal wound transforming growth factor-β regulation correlates with collagen organization. Am J Pathol 163:2459-76
    • (2003) Am J Pathol , vol.163 , pp. 2459-2476
    • Soo, C.1    Beanes, S.R.2    Hu, F.-Y.3    Zhang, X.4    Dang, C.5    Chang, G.6
  • 51
    • 0033899374 scopus 로고    scopus 로고
    • Differential expression of fibromodulin, a transforming growth factor-β modulator, in fetal skin development and scarless repair
    • Soo C, Hu F-Y, Zhang X, Wang Y, Beanes SR, Lorenz HP et al. (2000) Differential expression of fibromodulin, a transforming growth factor-β modulator, in fetal skin development and scarless repair. Am J Pathol 157:423-33
    • (2000) Am J Pathol , vol.157 , pp. 423-433
    • Soo, C.1    Hu, F.-Y.2    Zhang, X.3    Wang, Y.4    Beanes, S.R.5    Lorenz, H.P.6
  • 53
    • 0023631004 scopus 로고
    • Transforming growth factor beta causes a persistent increase in steady-state amounts for type I and type III collagen and fibronectin mRNAs in normal dermal human fibroblasts
    • Varga R, Jimenez SA (1987) Transforming growth factor beta causes a persistent increase in steady-state amounts for type I and type III collagen and fibronectin mRNAs in normal dermal human fibroblasts. Biochem J 297:597-604
    • (1987) Biochem J , vol.297 , pp. 597-604
    • Varga, R.1    Jimenez, S.A.2
  • 56
    • 0032529159 scopus 로고    scopus 로고
    • Smads and early developmental signaling by the TGFβ superfamily
    • Whitman M (1998) Smads and early developmental signaling by the TGFβ superfamily. Genes Dev 12:2445-62
    • (1998) Genes Dev , vol.12 , pp. 2445-2462
    • Whitman, M.1
  • 58
    • 0033527741 scopus 로고    scopus 로고
    • Smad7 differentially regulates transforming growth factor β-mediated signaling pathways
    • Zhu H-J, Iaria J, Sizeland AM (1999) Smad7 differentially regulates transforming growth factor β-mediated signaling pathways. J Biol Chem 274:32258-64
    • (1999) J Biol Chem , vol.274 , pp. 32258-32264
    • Zhu, H.-J.1    Iaria, J.2    Sizeland, A.M.3


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