-
2
-
-
34249814325
-
Pathophysiology of B-cell intrinsic immunoglobulin class switch recombination deficiencies
-
Durandy, A., N. Taubenheim, S. Peron, and A. Fischer. 2007. Pathophysiology of B-cell intrinsic immunoglobulin class switch recombination deficiencies. Adv. Immunol. 94: 275-306
-
(2007)
Adv. Immunol.
, vol.94
, pp. 275-306
-
-
Durandy, A.1
Taubenheim, N.2
Peron, S.3
Fischer, A.4
-
3
-
-
0027533185
-
Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM
-
Korthauer, U., D. Graf, H. W. Mages, et al. 1993. Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM. Nature 361: 539-541
-
(1993)
Nature
, vol.361
, pp. 539-541
-
-
Korthauer, U.1
Graf, D.2
Mages, H.W.3
-
4
-
-
0035940417
-
Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM
-
Ferrari, S., S. Giliani, A. Insalaco, et al. 2001. Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM. Proc. Natl. Acad. Sci. USA 98: 12614-12619
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12614-12619
-
-
Ferrari, S.1
Giliani, S.2
Insalaco, A.3
-
5
-
-
0030702854
-
Clinical spectrum of X-linked hyper-IgM syndrome
-
Levy, J., T. Espanol-Boren, C. Thomas, et al. 1997. Clinical spectrum of X-linked hyper-IgM syndrome. J. Pediatr. 131: 47-54
-
(1997)
J. Pediatr.
, vol.131
, pp. 47-54
-
-
Levy, J.1
Espanol-Boren, T.2
Thomas, C.3
-
6
-
-
0345276650
-
The X-linked hyper-IgM syndrome: Clinical and immunologic features of 79 patients
-
Winkelstein, J. A., M. C. Marino, H. Ochs, et al. 2003. The X-linked hyper-IgM syndrome: clinical and immunologic features of 79 patients. Medicine (Baltimore) 82: 373-384
-
(2003)
Medicine (Baltimore)
, vol.82
, pp. 373-384
-
-
Winkelstein, J.A.1
Marino, M.C.2
Ochs, H.3
-
7
-
-
0034264851
-
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
-
Revy, P., T. Muto, Y. Levy, et al. 2000. Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell 102: 565-575
-
(2000)
Cell
, vol.102
, pp. 565-575
-
-
Revy, P.1
Muto, T.2
Levy, Y.3
-
8
-
-
0037019315
-
AID mutates e coli suggesting a DNA deamination mechanism for antibody diversification
-
Petersen-Mahrt, S. K., R. S. Harris, and M. S. Neuberger. 2002. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 418: 99-104
-
(2002)
Nature
, vol.418
, pp. 99-104
-
-
Petersen-Mahrt, S.K.1
Harris, R.S.2
Neuberger, M.S.3
-
9
-
-
0037388165
-
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
-
Bransteitter, R., P. Pham, M. D. Scharff, and M. F. Goodman. 2003. Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc. Natl. Acad. Sci. USA 100: 4102-4107
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4102-4107
-
-
Bransteitter, R.1
Pham, P.2
Scharff, M.D.3
Goodman, M.F.4
-
10
-
-
79551681406
-
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates
-
Basu,U., F. L. Meng, C. Keim, et al. 2011. The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell 144: 353-363
-
(2011)
Cell
, vol.144
, pp. 353-363
-
-
Basu, U.1
Meng, F.L.2
Keim, C.3
-
11
-
-
19044396637
-
Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2
-
Imai, K., Y. Zhu, P. Revy, et al. 2005. Analysis of class switch recombination and somatic hypermutation in patients affected with autosomal dominant hyper-IgM syndrome type 2. Clin. Immunol. 115: 277-285
-
(2005)
Clin. Immunol.
, vol.115
, pp. 277-285
-
-
Imai, K.1
Zhu, Y.2
Revy, P.3
-
12
-
-
66149087337
-
The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence
-
Geisberger, R., C. Rada, and M. S. Neuberger. 2009. The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence. Proc. Natl. Acad. Sci. USA 106: 6736-6741
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 6736-6741
-
-
Geisberger, R.1
Rada, C.2
Neuberger, M.S.3
-
13
-
-
0142092610
-
Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
-
Imai, K., G. Slupphaug, W. I. Lee, et al. 2003. Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination. Nat. Immunol. 4: 1023-1028
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1023-1028
-
-
Imai, K.1
Slupphaug, G.2
Lee, W.I.3
-
14
-
-
6344256944
-
Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation
-
Rada, C., J. M. Di Noia, and M. S. Neuberger. 2004. Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation. Mol. Cell 16: 163-171
-
(2004)
Mol. Cell
, vol.16
, pp. 163-171
-
-
Rada, C.1
Di Noia, J.M.2
Neuberger, M.S.3
-
15
-
-
36549036731
-
APE1-and APE2-dependent DNA breaks in immunoglobulin class switch recombination
-
Guikema, J. E., E. K. Linehan, D. Tsuchimoto, et al. 2007. APE1-and APE2-dependent DNA breaks in immunoglobulin class switch recombination. J. Exp. Med. 204: 3017-3026
-
(2007)
J. Exp. Med.
, vol.204
, pp. 3017-3026
-
-
Guikema, J.E.1
Linehan, E.K.2
Tsuchimoto, D.3
-
16
-
-
33749519393
-
Somatic hypermutation and class switch recombination in Msh6(2/2)Ung(2/2) double-knockout mice
-
Shen, H. M., A. Tanaka, G. Bozek, D. Nicolae, and U. Storb. 2006. Somatic hypermutation and class switch recombination in Msh6(2/2)Ung(2/2) double-knockout mice. J. Immunol. 177: 5386-5392
-
(2006)
J. Immunol.
, vol.177
, pp. 5386-5392
-
-
Shen, H.M.1
Tanaka, A.2
Bozek, G.3
Nicolae, D.4
Storb, U.5
-
17
-
-
0035807955
-
Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination
-
Ehrenstein, M. R., C. Rada, A. M. Jones, C. Milstein, and M. S. Neuberger. 2001. Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination. Proc. Natl. Acad. Sci. USA 98: 14553-14558
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14553-14558
-
-
Ehrenstein, M.R.1
Rada, C.2
Jones, A.M.3
Milstein, C.4
Neuberger, M.S.5
-
18
-
-
0037017390
-
Role for Mismatch Repair Proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions
-
Schrader, C. E., J. Vardo, and J. Stavnezer. 2002. Role for Mismatch Repair Proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions. J. Exp. Med. 195: 367-373
-
(2002)
J. Exp. Med.
, vol.195
, pp. 367-373
-
-
Schrader, C.E.1
Vardo, J.2
Stavnezer, J.3
-
19
-
-
58149165112
-
Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination
-
Peron, S., A. Metin, P. Gardes, et al. 2008. Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination. J. Exp. Med. 205: 2465-2472
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2465-2472
-
-
Peron, S.1
Metin, A.2
Gardes, P.3
-
20
-
-
84856895159
-
Human MSH6 deficiency is associated with impaired antibody maturation
-
Gardes, P., M. Forveille, M. A. Alyanakian, et al. 2012. Human MSH6 deficiency is associated with impaired antibody maturation. J. Immunol. 188: 2023-2029
-
(2012)
J. Immunol.
, vol.188
, pp. 2023-2029
-
-
Gardes, P.1
Forveille, M.2
Alyanakian, M.A.3
-
21
-
-
34748863465
-
IgH class switching and translocations use a robust non-classical endjoining pathway
-
Yan, C. T., C. Boboila, E. K. Souza, et al. 2007. IgH class switching and translocations use a robust non-classical endjoining pathway. Nature 449: 478-482
-
(2007)
Nature
, vol.449
, pp. 478-482
-
-
Yan, C.T.1
Boboila, C.2
Souza, E.K.3
-
22
-
-
0041381361
-
AID mutant analyses indicate requirement for class-switch-specific cofactors
-
Ta, V. T., H. Nagaoka, N. Catalan, et al. 2003. AID mutant analyses indicate requirement for class-switch-specific cofactors. Nat. Immunol. 4: 843-848
-
(2003)
Nat. Immunol.
, vol.4
, pp. 843-848
-
-
Ta, V.T.1
Nagaoka, H.2
Catalan, N.3
-
23
-
-
0141992113
-
C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion
-
Barreto, V., B. Reina-San-Martin, A. R. Ramiro, K. M. McBride, and M. C. Nussenzweig. 2003. C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. Mol. Cell 12: 501-508
-
(2003)
Mol. Cell
, vol.12
, pp. 501-508
-
-
Barreto, V.1
Reina-San-Martin, B.2
Ramiro, A.R.3
McBride, K.M.4
Nussenzweig, M.C.5
-
24
-
-
79960998395
-
Activationinduced cytidine deaminase (AID) is required for B-cell tolerance in humans
-
Meyers, G., Y. S. Ng, J. M. Bannock, et al. 2011. Activationinduced cytidine deaminase (AID) is required for B-cell tolerance in humans. Proc. Natl. Acad. Sci. USA 108: 11554-11559
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11554-11559
-
-
Meyers, G.1
Ng, Y.S.2
Bannock, J.M.3
-
25
-
-
34447288471
-
CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance
-
Herve, M., I. Isnardi, Y. S. Ng, et al. 2007. CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance. J. Exp. Med. 204: 1583-1593
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1583-1593
-
-
Herve, M.1
Isnardi, I.2
Ng, Y.S.3
-
26
-
-
1242296822
-
Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
-
Suzuki, K., B. Meek, Y. Doi, et al. 2004. Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut. Proc. Natl. Acad. Sci. USA 101: 1981-1986
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1981-1986
-
-
Suzuki, K.1
Meek, B.2
Doi, Y.3
-
27
-
-
10744226125
-
Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency
-
Quartier, P., J. Bustamante, O. Sanal, et al. 2004. Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency. Clin. Immunol. 110: 22-29
-
(2004)
Clin. Immunol.
, vol.110
, pp. 22-29
-
-
Quartier, P.1
Bustamante, J.2
Sanal, O.3
-
28
-
-
0029933493
-
Hyper-IgM syndrome associated with rheumatoid arthritis: Report of RA in a patient with primary impaired CD40 pathway
-
Sibilia, J., A. Durandy, T. Schaeverbeke, and J. P. Fermand. 1996. Hyper-IgM syndrome associated with rheumatoid arthritis: report of RA in a patient with primary impaired CD40 pathway. Br. J. Rheumatol. 35: 282-284
-
(1996)
Br. J. Rheumatol.
, vol.35
, pp. 282-284
-
-
Sibilia, J.1
Durandy, A.2
Schaeverbeke, T.3
Fermand, J.P.4
-
29
-
-
0041689676
-
Predominant autoantibody production by early human B cell precursors
-
Wardemann, H., S. Yurasov, A. Schaefer, et al. 2003. Predominant autoantibody production by early human B cell precursors. Science 301: 1374-1377
-
(2003)
Science
, vol.301
, pp. 1374-1377
-
-
Wardemann, H.1
Yurasov, S.2
Schaefer, A.3
-
30
-
-
0037375554
-
Antigen receptor selection by editing or downregulation of V(D)J recombination
-
Nemazee, D., and K. A. Hogquist. 2003. Antigen receptor selection by editing or downregulation of V(D)J recombination. Curr. Opin. Immunol. 15: 182-189
-
(2003)
Curr. Opin. Immunol.
, vol.15
, pp. 182-189
-
-
Nemazee, D.1
Hogquist, K.A.2
-
31
-
-
80052376347
-
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans
-
Menard, L., D. Saadoun, I. Isnardi, et al. 2011. The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. J. Clin. Invest. 121: 3635-3644
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3635-3644
-
-
Menard, L.1
Saadoun, D.2
Isnardi, I.3
-
32
-
-
55349142293
-
IRAK-4-and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans
-
Isnardi, I., Y. S. Ng, I. Srdanovic, et al. 2008. IRAK-4-and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. Immunity 29: 746-757
-
(2008)
Immunity
, vol.29
, pp. 746-757
-
-
Isnardi, I.1
Ng, Y.S.2
Srdanovic, I.3
-
33
-
-
84861833417
-
Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy
-
Sauer, A. V., H. Morbach, I. Brigida, et al. 2012. Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy. J. Clin. Invest. 122: 2141-2152
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2141-2152
-
-
Sauer, A.V.1
Morbach, H.2
Brigida, I.3
-
34
-
-
1342265786
-
T cellindependent somatic hypermutation in murine B cells with an immature phenotype
-
Mao, C., L. Jiang, M. Melo-Jorge, et al. 2004. T cellindependent somatic hypermutation in murine B cells with an immature phenotype. Immunity 20: 133-144
-
(2004)
Immunity
, vol.20
, pp. 133-144
-
-
Mao, C.1
Jiang, L.2
Melo-Jorge, M.3
-
35
-
-
34447617375
-
Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors
-
Han, J. H., S. Akira, K. Calame, et al. 2007. Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors. Immunity 27: 64-75
-
(2007)
Immunity
, vol.27
, pp. 64-75
-
-
Han, J.H.1
Akira, S.2
Calame, K.3
-
36
-
-
33947216515
-
T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells
-
Ueda, Y., D. Liao, K. Yang, A. Patel, and G. Kelsoe. 2007. T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells. J. Immunol. 178: 3593-3601
-
(2007)
J. Immunol.
, vol.178
, pp. 3593-3601
-
-
Ueda, Y.1
Liao, D.2
Yang, K.3
Patel, A.4
Kelsoe, G.5
-
37
-
-
70349260308
-
Activationinduced cytidine deaminase expression and activity in the absence of germinal centers: Insights into hyper-IgM syndrome
-
Kuraoka, M., D. Liao, K. Yang, et al. 2009. Activationinduced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome. J. Immunol. 183: 3237-3248
-
(2009)
J. Immunol.
, vol.183
, pp. 3237-3248
-
-
Kuraoka, M.1
Liao, D.2
Yang, K.3
-
38
-
-
79961011020
-
Activationinduced cytidine deaminase mediates central tolerance in B cells
-
Kuraoka, M., T. M. Holl, D. Liao, et al. 2011. Activationinduced cytidine deaminase mediates central tolerance in B cells. Proc. Natl. Acad. Sci. USA 108: 11560-11565
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11560-11565
-
-
Kuraoka, M.1
Holl, T.M.2
Liao, D.3
-
39
-
-
0029076561
-
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4 T cells
-
Rathmell, J. C., M. P. Cooke, W. Y. Ho, et al. 1995. CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4 T cells. Nature 376: 181-184
-
(1995)
Nature
, vol.376
, pp. 181-184
-
-
Rathmell, J.C.1
Cooke, M.P.2
Ho, W.Y.3
-
40
-
-
0030592564
-
Expansion or elimination of B cells in vivo: Dual roles for CD40-and Fas (CD95)-ligands modulated by the B cell antigen receptor
-
Rathmell, J. C., S. E. Townsend, J. C. Xu, R. A. Flavell, and C. C. Goodnow. 1996. Expansion or elimination of B cells in vivo: dual roles for CD40-and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 87: 319-329
-
(1996)
Cell
, vol.87
, pp. 319-329
-
-
Rathmell, J.C.1
Townsend, S.E.2
Xu, J.C.3
Flavell, R.A.4
Goodnow, C.C.5
-
41
-
-
0035860559
-
An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway
-
Schiemann, B., J. L. Gommerman, K. Vora, et al. 2001. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science 293: 2111-2114
-
(2001)
Science
, vol.293
, pp. 2111-2114
-
-
Schiemann, B.1
Gommerman, J.L.2
Vora, K.3
-
42
-
-
0033428703
-
Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
-
Mackay, F., S. A. Woodcock, P. Lawton, et al. 1999. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J. Exp. Med. 190: 1697-1710
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1697-1710
-
-
MacKay, F.1
Woodcock, S.A.2
Lawton, P.3
-
43
-
-
0023251534
-
The role of clonal selection and somatic mutation in autoimmunity
-
Shlomchik,M. J., A. Marshak-Rothstein, C.B.Wolfowicz,T. L. Rothstein, and M. G. Weigert. 1987. The role of clonal selection and somatic mutation in autoimmunity. Nature 328: 805-811
-
(1987)
Nature
, vol.328
, pp. 805-811
-
-
Shlomchik, M.J.1
Marshak-Rothstein, A.2
Wolfowicz, C.B.3
Rothstein, T.L.4
Weigert, M.G.5
-
44
-
-
0025583751
-
Pathogenic anti-DNA antibodies in SLE: Idiotypic families and genetic origins
-
Paul, E., A. Manheimer-Lory, A. Livneh, et al. 1990. Pathogenic anti-DNA antibodies in SLE: idiotypic families and genetic origins. Int. Rev. Immunol. 5: 295-313
-
(1990)
Int. Rev. Immunol.
, vol.5
, pp. 295-313
-
-
Paul, E.1
Manheimer-Lory, A.2
Livneh, A.3
-
45
-
-
0025978752
-
Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus
-
van Es, J. H., F. H. Gmelig Meyling,W. R. van de Akker, et al. 1991. Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus. J. Exp. Med. 173: 461-470
-
(1991)
J. Exp. Med.
, vol.173
, pp. 461-470
-
-
Van Es, J.H.1
Gmelig Meyling, F.H.2
Van De Akker, W.R.3
-
46
-
-
0032169223
-
Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjogren's syndrome
-
Stott, D. I., F. Hiepe, M. Hummel, G. Steinhauser, and C. Berek. 1998. Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjogren's syndrome. J. Clin. Invest. 102: 938-946
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 938-946
-
-
Stott, D.I.1
Hiepe, F.2
Hummel, M.3
Steinhauser, G.4
Berek, C.5
-
47
-
-
0035881829
-
Somatic hypermutation and selection of B cells in thymic germinal centers responding to acetylcholine receptor in myasthenia gravis
-
Sims, G. P., H. Shiono, N. Willcox, and D. I. Stott. 2001. Somatic hypermutation and selection of B cells in thymic germinal centers responding to acetylcholine receptor in myasthenia gravis. J. Immunol. 167: 1935-1944
-
(2001)
J. Immunol.
, vol.167
, pp. 1935-1944
-
-
Sims, G.P.1
Shiono, H.2
Willcox, N.3
Stott, D.I.4
-
48
-
-
21544463136
-
The evolution of human anti-double-stranded DNA autoantibodies
-
Wellmann, U., M. Letz, M. Herrmann, et al. 2005. The evolution of human anti-double-stranded DNA autoantibodies. Proc. Natl. Acad. Sci. USA 102: 9258-9263
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9258-9263
-
-
Wellmann, U.1
Letz, M.2
Herrmann, M.3
-
49
-
-
84864968123
-
Activation-induced deaminase contributes to the antibodyindependent role of B cells in the development of autoimmunity
-
Jiang, C., M. L. Zhao, K. M. Waters, and M. Diaz. 2012. Activation-induced deaminase contributes to the antibodyindependent role of B cells in the development of autoimmunity. Autoimmunity 45: 440-448
-
(2012)
Autoimmunity
, vol.45
, pp. 440-448
-
-
Jiang, C.1
Zhao, M.L.2
Waters, K.M.3
Diaz, M.4
-
50
-
-
34249826624
-
Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice
-
Jiang, C., J. Foley, N. Clayton, et al. 2007. Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr mice. J. Immunol. 178: 7422-7431
-
(2007)
J. Immunol.
, vol.178
, pp. 7422-7431
-
-
Jiang, C.1
Foley, J.2
Clayton, N.3
-
51
-
-
57449111276
-
Activation-induced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis
-
Jiang, C., M. L. Zhao, and M. Diaz. 2009. Activation-induced deaminase heterozygous MRL/lpr mice are delayed in the production of high-affinity pathogenic antibodies and in the development of lupus nephritis. Immunology 126: 102-113
-
(2009)
Immunology
, vol.126
, pp. 102-113
-
-
Jiang, C.1
Zhao, M.L.2
Diaz, M.3
-
52
-
-
59049098881
-
Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: Concurrent upregulation of somatic hypermutation and class switch DNA recombination
-
Zan, H., J. Zhang, S. Ardeshna, et al. 2009. Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination. Autoimmunity 42: 89-103
-
(2009)
Autoimmunity
, vol.42
, pp. 89-103
-
-
Zan, H.1
Zhang, J.2
Ardeshna, S.3
-
53
-
-
51849125587
-
Activationinduced cytidine deaminase deficiency causes organ-specific autoimmune disease
-
Hase, K., D. Takahashi, M. Ebisawa, et al. 2008. Activationinduced cytidine deaminase deficiency causes organ-specific autoimmune disease. PLoS One 3: e3033
-
(2008)
PLoS One
, vol.3
-
-
Hase, K.1
Takahashi, D.2
Ebisawa, M.3
-
54
-
-
70149094600
-
AID constrains germinal center size by rendering B cells susceptible to apoptosis
-
Zaheen, A., B. Boulianne, J. Y. Parsa, et al. 2009. AID constrains germinal center size by rendering B cells susceptible to apoptosis. Blood 114: 547-554
-
(2009)
Blood
, vol.114
, pp. 547-554
-
-
Zaheen, A.1
Boulianne, B.2
Parsa, J.Y.3
-
55
-
-
10644282845
-
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming
-
Morgan, H. D., W. Dean, H. A. Coker, W. Reik, and S. K. Petersen-Mahrt. 2004. Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J. Biol. Chem. 279: 52353-52360
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 52353-52360
-
-
Morgan, H.D.1
Dean, W.2
Coker, H.A.3
Reik, W.4
Petersen-Mahrt, S.K.5
-
56
-
-
57649196594
-
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
-
Rai, K., I. J. Huggins, S. R. James, et al. 2008. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 135: 1201-1212
-
(2008)
Cell
, vol.135
, pp. 1201-1212
-
-
Rai, K.1
Huggins, I.J.2
James, S.R.3
-
57
-
-
77649104794
-
Reprogramming towards pluripotency requires AID-dependent DNA demethylation
-
Bhutani, N., J. J. Brady, M. Damian, et al. 2010. Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature 463: 1042-1047
-
(2010)
Nature
, vol.463
, pp. 1042-1047
-
-
Bhutani, N.1
Brady, J.J.2
Damian, M.3
-
58
-
-
77249148019
-
Genome-wide erasure of DNA methylation in mouse primordial germcells is affected by AID deficiency
-
Popp, C.,W. Dean, S. Feng, et al. 2010. Genome-wide erasure of DNA methylation in mouse primordial germcells is affected by AID deficiency. Nature 463: 1101-1105
-
(2010)
Nature
, vol.463
, pp. 1101-1105
-
-
Popp, C.1
Dean, W.2
Feng, S.3
-
59
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett, C. L., J. Christie, F. Ramsdell, et al. 2001. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27: 20-21
-
(2001)
Nat. Genet.
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
-
60
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M. E., E. W. Jeffery, K. A. Hjerrild, et al. 2001. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27: 68-73
-
(2001)
Nat. Genet.
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
-
61
-
-
84555203265
-
Activationinduced cytidine deaminase expression in CD4 T cells is associated with a unique IL-10-producing subset that increases with age
-
Qin, H., K. Suzuki, M. Nakata, et al. 2011. Activationinduced cytidine deaminase expression in CD4 T cells is associated with a unique IL-10-producing subset that increases with age. PLoS One 6: e29141
-
(2011)
PLoS One
, vol.6
-
-
Qin, H.1
Suzuki, K.2
Nakata, M.3
-
62
-
-
0033577903
-
A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
-
Chan, O. T., L. G. Hannum, A. M. Haberman, M. P. Madaio, and M. J. Shlomchik. 1999. A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J. Exp. Med. 189: 1639-1648
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1639-1648
-
-
Chan, O.T.1
Hannum, L.G.2
Haberman, A.M.3
Madaio, M.P.4
Shlomchik, M.J.5
-
63
-
-
77957729025
-
Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity
-
Guo, W., D. Smith, K. Aviszus, et al. 2010. Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity. J. Exp. Med. 207: 2225-2237
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2225-2237
-
-
Guo, W.1
Smith, D.2
Aviszus, K.3
|