Facile synthesis of [1,2,3]-triazole-fused isoindolines, tetrahydroisoquinolines, benzoazepines and benzoazocines by palladium-copper catalysed heterocyclisation

Synthesis (Germany)

Volumn 45, Issue 4, 2013, Pages 545-555

  Brahma, Kaushik ^a   Achari, Basudeb ^a   Chowdhury, Chinmay ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

1,2,3 triazoles; azide alkyne cycloaddition; bis heteroannulations; intramolecular reactions; nitrogen heterocycles

Indexed keywords

1 ,2 ,3-TRIAZOLES; AZIDE-ALKYNE CYCLOADDITION; BIS-HETEROANNULATIONS; INTRAMOLECULAR REACTIONS; NITROGEN HETEROCYCLES;

ACETYLENE; AROMATIC COMPOUNDS; COPPER; SUBSTRATES;

CATALYSIS;

1 (2,4 DIMETHOXYPYRIMIDIN 5 YL) 5,6 DIHYDRO[1,2,3]TRIAZOLO[5,1 A]ISOQUINOLINE; 1 (2,4 DIMETHOXYPYRIMIDIN 5 YL) 6,7 DIHYDRO 5H BENZO[C][1,2,3]TRIAZOLO[1,5 A]AZEPINE; 1 (4 CARBOMETHOXYPHENYL) 5,6,7,8 TETRAHYDROBENZO[C][1,2,3]TRIAZOLO[1,5 A]AZOCINE; 1 (4 METHOXYPHENYL) 5,6 DIHYDRO[1,2,3]TRIAZOLO[5,1 A]ISOQUINOLINE; 1 (4 METHOXYPHENYL) 5,6,7,8 TETRAHYDROBENZO[C][1,2,3]TRIAZOLO[1,5 A]AZOCINE; 1 (4 METHOXYPHENYL) 6,7 DIHYDRO 5H BENZO[C] [1,2,3]TRIAZOLO[1,5 A]AZEPINE; 1 (4 NITROPHENYL) 5,6 DIHYDRO[1,2,3]TRIAZOLO[5,1 A]ISOQUINOLINE; 1 (4 NITROPHENYL) 6,7 DIHYDRO 5H BENZO[C][1,2,3]TRIAZOLO[1,5 A]AZEPINE; 1 (PHENYL) 6,7 DIHYDRO 5H BENZO[C][1,2,3]TRIAZOLO[1,5 A]AZEPINE; 1 [[5 (2,2 DIMETHYL 1,3 DIOXOLAN 4 YL) 2,2 DIMETHYLTETRAHYDROFURO[3,2 D][1,3]DIOXOL 6 YL OXY]METHYL] 6,7 DIHYDRO 5H BENZO[C][1,2,3]TRIAZOLO[1,5 A]AZEPINE; 1 [[5 (2,2 DIMETHYL 1,3 DIOXOLAN 4 YL) 2,2 DIMETHYLTETRAHYDROFURO[3,2 D][1,3]DIOXOL 6 YLOXY]METHYL] 5,6 DIHYDRO[1,2,3]TRIAZOLO[5,1 A]ISOQUINOLINE; 1 PHENYL 5,6 DIHYDRO[1,2,3]TRIAZOLO[5,1 A]ISOQUINOLINE; 1 VINYL 5,6 DIHYDRO[1,2,3]TRIAZOLO[5,1 A]ISOQUINOLINE; 1,2,3 TRIAZOLE DERIVATIVE; 3 (4 METHOXYPHENYL) 8H [1,2,3]TRIAZOLO[5,1 A]ISOINDOLE; 3 BUTYL 8H [1,2,3]TRIAZOLO[5,1 A]ISOINDOLE; 3 PHENYL 8H [1,2,3]TRIAZOLO[5,1 A]ISOINDOLE; BENZAZEPINE DERIVATIVE; BENZAZOCINE DERIVATIVE; CHEMICAL COMPOUND; COPPER; METHYL 4 (8H [1,2,3]TRIAZOLO[5,1 A]ISOINDOL 3 YL)BENZOATE; PALLADIUM; PHENYL 5,6,7,8 TETRAHYDROBENZO[C][1,2,3]TRIAZOLO[1,5 A]AZOCINE; TETRAHYDROISOQUINOLINE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; CONFORMATIONAL TRANSITION; CYCLIZATION; HEATING; MELTING POINT; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84873570152     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0032-1316839     Document Type: Article

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