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Volumn 34, Issue 2, 2013, Pages 325-330

Genotoxicity of alcohol is linked to DNA replication-associated damage and homologous recombination repair

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALCOHOL; RAD51 PROTEIN;

EID: 84873553362     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs340     Document Type: Article
Times cited : (31)

References (38)
  • 1
    • 34547118090 scopus 로고    scopus 로고
    • Molecular mechanisms of alcohol-mediated carcinogenesis
    • Seitz,H.K. et al. (2007) Molecular mechanisms of alcohol-mediated carcinogenesis. Nat. Rev. Cancer, 7, 599-612.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 599-612
    • Seitz, H.K.1
  • 2
    • 0034007897 scopus 로고    scopus 로고
    • Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer
    • Homann,N. et al. (2000) Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer. Carcinogenesis, 21, 663-668.
    • (2000) Carcinogenesis , vol.21 , pp. 663-668
    • Homann, N.1
  • 3
    • 47149099913 scopus 로고    scopus 로고
    • The role of acetaldehyde outside ethanol metabolism in the carcinogenicity of alcoholic beverages: evidence from a large chemical survey
    • Lachenmeier,D.W. et al. (2008) The role of acetaldehyde outside ethanol metabolism in the carcinogenicity of alcoholic beverages: evidence from a large chemical survey. Food Chem. Toxicol., 46, 2903-2911.
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 2903-2911
    • Lachenmeier, D.W.1
  • 4
    • 62649117732 scopus 로고    scopus 로고
    • Acetaldehyde: a cumulative carcinogen in humans
    • Salaspuro,M. (2009) Acetaldehyde: a cumulative carcinogen in humans. Addiction, 104, 551-553.
    • (2009) Addiction , vol.104 , pp. 551-553
    • Salaspuro, M.1
  • 5
    • 0030938094 scopus 로고    scopus 로고
    • The changing cigarette 1950-1995
    • Hoffmann,D. et al. (1997) The changing cigarette, 1950-1995. J. Toxicol. Environ. Health, 50, 307-364.
    • (1997) J. Toxicol. Environ. Health , vol.50 , pp. 307-364
    • Hoffmann, D.1
  • 6
    • 77957898461 scopus 로고    scopus 로고
    • Research recommendations for selected IARCclassified agents
    • Ward,E.M. et al. (2010) Research recommendations for selected IARCclassified agents. Environ. Health Perspect., 118, 1355-1362.
    • (2010) Environ. Health Perspect. , vol.118 , pp. 1355-1362
    • Ward, E.M.1
  • 7
    • 33644623520 scopus 로고    scopus 로고
    • Formation and repair of interstrand cross-links in DNA
    • Noll,D.M. et al. (2006) Formation and repair of interstrand cross-links in DNA. Chem. Rev., 106, 277-301.
    • (2006) Chem. Rev. , vol.106 , pp. 277-301
    • Noll, D.M.1
  • 8
    • 23144448354 scopus 로고    scopus 로고
    • DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis
    • Brooks,P.J. et al. (2005) DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis. Alcohol, 35, 187-193.
    • (2005) Alcohol , vol.35 , pp. 187-193
    • Brooks, P.J.1
  • 9
    • 0034626885 scopus 로고    scopus 로고
    • Inhibition of DNA synthesis is a potent mechanism by which cytostatic drugs induce homologous recombination in mammalian cells
    • Arnaudeau,C. et al. (2000) Inhibition of DNA synthesis is a potent mechanism by which cytostatic drugs induce homologous recombination in mammalian cells. Mutat. Res., 461, 221-228.
    • (2000) Mutat. Res. , vol.461 , pp. 221-228
    • Arnaudeau, C.1
  • 10
    • 0037177577 scopus 로고    scopus 로고
    • Hemoglobin adducts and micronucleus frequencies in mouse and rat after acrylamide or N-methylolacrylamide treatment
    • Paulsson,B. et al. (2002) Hemoglobin adducts and micronucleus frequencies in mouse and rat after acrylamide or N-methylolacrylamide treatment. Mutat. Res., 516, 101-111.
    • (2002) Mutat. Res. , vol.516 , pp. 101-111
    • Paulsson, B.1
  • 11
    • 16644375676 scopus 로고    scopus 로고
    • Flow cytometric analysis of micronuclei in erythrocytes
    • Grawé,J. (2005) Flow cytometric analysis of micronuclei in erythrocytes. Methods Mol. Biol., 291, 69-83.
    • (2005) Methods Mol. Biol. , vol.291 , pp. 69-83
    • Grawé, J.1
  • 12
    • 0033036461 scopus 로고    scopus 로고
    • Effects of three epoxides-ethylene oxide, propylene oxide and epichlorohydrin-on cell cycle progression and cell death in human diploid fibroblasts
    • Mlejnek,P. et al. (1999) Effects of three epoxides-ethylene oxide, propylene oxide and epichlorohydrin-on cell cycle progression and cell death in human diploid fibroblasts. Chem. Biol. Interact., 117, 219-239.
    • (1999) Chem. Biol. Interact. , vol.117 , pp. 219-239
    • Mlejnek, P.1
  • 13
    • 16544387211 scopus 로고    scopus 로고
    • A method to monitor replication fork progression in mammalian cells: nucleotide excision repair enhances and homologous recombination delays elongation along damaged DNA
    • Johansson,F. et al. (2004) A method to monitor replication fork progression in mammalian cells: nucleotide excision repair enhances and homologous recombination delays elongation along damaged DNA. Nucleic Acids Res., 32, e157.
    • (2004) Nucleic Acids Res , vol.32
    • Johansson, F.1
  • 14
    • 0032546733 scopus 로고    scopus 로고
    • A partial hprt gene duplication generated by nonhomologous recombination in V79 Chinese hamster cells is eliminated by homologous recombination
    • Helleday,T. et al. (1998) A partial hprt gene duplication generated by nonhomologous recombination in V79 Chinese hamster cells is eliminated by homologous recombination. J. Mol. Biol., 279, 687-694.
    • (1998) J. Mol. Biol. , vol.279 , pp. 687-694
    • Helleday, T.1
  • 15
    • 79955834166 scopus 로고    scopus 로고
    • Transcription inhibition by DRB potentiates recombinational repair of UV lesions in mammalian cells
    • Stoimenov,I. et al. (2011) Transcription inhibition by DRB potentiates recombinational repair of UV lesions in mammalian cells. PLoS ONE, 6, e19492.
    • (2011) PLoS ONE , vol.6
    • Stoimenov, I.1
  • 16
    • 0028235879 scopus 로고
    • Pathobiological effects of acetaldehyde in cultured human epithelial cells and fibroblasts
    • Grafström,R.C. et al. (1994) Pathobiological effects of acetaldehyde in cultured human epithelial cells and fibroblasts. Carcinogenesis, 15, 985-990.
    • (1994) Carcinogenesis , vol.15 , pp. 985-990
    • Grafström, R.C.1
  • 17
    • 67349227771 scopus 로고    scopus 로고
    • Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesis
    • Marietta,C. et al. (2009) Acetaldehyde stimulates FANCD2 monoubiquitination, H2AX phosphorylation, and BRCA1 phosphorylation in human cells in vitro: implications for alcohol-related carcinogenesis. Mutat. Res., 664, 77-83.
    • (2009) Mutat. Res. , vol.664 , pp. 77-83
    • Marietta, C.1
  • 18
    • 0037414420 scopus 로고    scopus 로고
    • RAD51 is involved in repair of damage associated with DNA replication in mammalian cells
    • Lundin,C. et al. (2003) RAD51 is involved in repair of damage associated with DNA replication in mammalian cells. J. Mol. Biol., 328, 521-535.
    • (2003) J. Mol. Biol. , vol.328 , pp. 521-535
    • Lundin, C.1
  • 19
    • 0031878859 scopus 로고    scopus 로고
    • Effects of carcinogenic agents upon different mechanisms for intragenic recombination in mammalian cells
    • Helleday,T. et al. (1998) Effects of carcinogenic agents upon different mechanisms for intragenic recombination in mammalian cells. Carcinogenesis, 19, 973-978.
    • (1998) Carcinogenesis , vol.19 , pp. 973-978
    • Helleday, T.1
  • 20
    • 0024993053 scopus 로고
    • Animal cell DNA polymerases in DNA repair
    • Perrino,F.W. et al. (1990) Animal cell DNA polymerases in DNA repair. Mutat. Res., 236, 289-300.
    • (1990) Mutat. Res. , vol.236 , pp. 289-300
    • Perrino, F.W.1
  • 21
    • 0344443730 scopus 로고    scopus 로고
    • Azide-alkyne coupling: a powerful reaction for bioconjugate chemistry
    • Breinbauer,R. et al. (2003) Azide-alkyne coupling: a powerful reaction for bioconjugate chemistry. Chembiochem, 4, 1147-1149.
    • (2003) Chembiochem , vol.4 , pp. 1147-1149
    • Breinbauer, R.1
  • 22
    • 0036316015 scopus 로고    scopus 로고
    • Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells
    • Lundin,C. et al. (2002) Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells. Mol. Cell. Biol., 22, 5869-5878.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5869-5878
    • Lundin, C.1
  • 23
    • 60449083664 scopus 로고    scopus 로고
    • Relationship between DNA lesions DNA repair and chromosomal damage induced by acetaldehyde
    • Lorenti Garcia,C. et al. (2009) Relationship between DNA lesions, DNA repair and chromosomal damage induced by acetaldehyde. Mutat. Res., 662, 3-9.
    • (2009) Mutat. Res. , vol.662 , pp. 3-9
    • Lorenti Garcia, C.1
  • 24
    • 38549112054 scopus 로고    scopus 로고
    • DNA repair deficiency and acetaldehyde-induced chromosomal alterations in CHO cells
    • Mechilli,M. et al. (2008) DNA repair deficiency and acetaldehyde-induced chromosomal alterations in CHO cells. Mutagenesis, 23, 51-56.
    • (2008) Mutagenesis , vol.23 , pp. 51-56
    • Mechilli, M.1
  • 25
    • 0017852041 scopus 로고
    • Acetaldehyde induces cross-links in DNA and causes sister-chromatid exchanges in human cells
    • Ristow,H. et al. (1978) Acetaldehyde induces cross-links in DNA and causes sister-chromatid exchanges in human cells. Mutat. Res., 58, 115-119.
    • (1978) Mutat. Res. , vol.58 , pp. 115-119
    • Ristow, H.1
  • 26
    • 0018718996 scopus 로고
    • Induction of chromosomal aberrations in peripheral lymphocytes of human blood in vitro, and of SCEs in bone-marrow cells of mice in vivo by ethanol and its metabolite acetaldehyde
    • Obe,G. et al. (1979) Induction of chromosomal aberrations in peripheral lymphocytes of human blood in vitro, and of SCEs in bone-marrow cells of mice in vivo by ethanol and its metabolite acetaldehyde. Mutat. Res., 68, 291-294.
    • (1979) Mutat. Res. , vol.68 , pp. 291-294
    • Obe, G.1
  • 27
    • 79960037006 scopus 로고    scopus 로고
    • Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice
    • Langevin,F. et al. (2011) Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice. Nature, 475, 53-58.
    • (2011) Nature , vol.475 , pp. 53-58
    • Langevin, F.1
  • 28
    • 0035853295 scopus 로고    scopus 로고
    • DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells
    • Arnaudeau,C. et al. (2001) DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells. J. Mol. Biol., 307, 1235-1245.
    • (2001) J. Mol. Biol. , vol.307 , pp. 1235-1245
    • Arnaudeau, C.1
  • 29
    • 0346340054 scopus 로고    scopus 로고
    • RAD51C is required for Holliday junction processing in mammalian cells
    • Liu,Y. et al. (2004) RAD51C is required for Holliday junction processing in mammalian cells. Science, 303, 243-246.
    • (2004) Science , vol.303 , pp. 243-246
    • Liu, Y.1
  • 30
    • 0033569684 scopus 로고    scopus 로고
    • XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
    • Pierce,A.J. et al. (1999) XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. Genes Dev., 13, 2633-2638.
    • (1999) Genes Dev , vol.13 , pp. 2633-2638
    • Pierce, A.J.1
  • 31
    • 33750206776 scopus 로고    scopus 로고
    • The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks
    • Hanada,K. et al. (2006) The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. EMBO J., 25, 4921-4932.
    • (2006) EMBO J , vol.25 , pp. 4921-4932
    • Hanada, K.1
  • 33
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2AX in response to DNA double-strand breaks
    • Burma,S. et al. (2001) ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem., 276, 42462-42467.
    • (2001) J. Biol. Chem. , vol.276 , pp. 42462-42467
    • Burma, S.1
  • 34
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • Paull,T.T. et al. (2000) A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol., 10, 886-895.
    • (2000) Curr. Biol. , vol.10 , pp. 886-895
    • Paull, T.T.1
  • 35
    • 0035851090 scopus 로고    scopus 로고
    • Nuclear retention of ATM at sites of DNA double strand breaks
    • Andegeko,Y. et al. (2001) Nuclear retention of ATM at sites of DNA double strand breaks. J. Biol. Chem., 276, 38224-38230.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38224-38230
    • Andegeko, Y.1
  • 36
    • 0036903037 scopus 로고    scopus 로고
    • DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1
    • Fernandez-Capetillo,O. et al. (2002) DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat. Cell Biol., 4, 993-997.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 993-997
    • Fernandez-Capetillo, O.1
  • 37
    • 72049099843 scopus 로고    scopus 로고
    • The in vitro genotoxicity of ethanol and acetaldehyde
    • Kayani,M.A. et al. (2010) The in vitro genotoxicity of ethanol and acetaldehyde. Toxicol. In Vitro, 24, 56-60.
    • (2010) Toxicol. In Vitro , vol.24 , pp. 56-60
    • Kayani, M.A.1
  • 38
    • 0033601808 scopus 로고    scopus 로고
    • The micronucleus test in rat erythrocytes from bone marrow, spleen and peripheral blood: the response to low doses of ionizing radiation, cyclophosphamide and vincristine determined by flow cytometry
    • Abramsson-Zetterberg,L. et al. (1999) The micronucleus test in rat erythrocytes from bone marrow, spleen and peripheral blood: the response to low doses of ionizing radiation, cyclophosphamide and vincristine determined by flow cytometry. Mutat. Res., 423, 113-124.
    • (1999) Mutat. Res. , vol.423 , pp. 113-124
    • Abramsson-Zetterberg, L.1


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