Prolonged apoptotic cell accumulation in germinal centers of mer-deficient mice causes elevated B cell and CD4+ Th cell responses leading to autoantibody production

Journal of Immunology

Volumn 190, Issue 4, 2013, Pages 1433-1446

  Khan, Tahsin N ^a,b   Wong, Eric B ^a,b   Soni, Chetna ^a,b   Rahman, Ziaur S M ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CD4 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2 ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 6; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY TITER; APOPTOSIS; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GERMINAL CENTER; IMMUNOLOGICAL TOLERANCE; IMMUNOREACTIVITY; LYMPHOCYTE PROLIFERATION; MALE; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN; TH1 CELL; TH2 CELL;

ANIMALS; APOPTOSIS; AUTOANTIBODIES; B-LYMPHOCYTE SUBSETS; CELL AGGREGATION; GERMINAL CENTER; LYMPHOCYTE ACTIVATION; MICE; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; SPLEEN; T-LYMPHOCYTES, HELPER-INDUCER; TIME FACTORS; UP-REGULATION;

EID: 84873539950     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200824     Document Type: Article

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