Oroxylin A Inhibits Hemolysis via Hindering the Self-Assembly of α-Hemolysin Heptameric Transmembrane Pore

PLoS Computational Biology

Volumn 9, Issue 1, 2013, Pages

  Dong, Jing ^a   Qiu, Jiazhang ^a   Zhang, Yu ^a   Lu, Chongjian ^a   Dai, Xiaohan ^a   Wang, Jianfeng ^a   Li, Hongen ^a   Wang, Xin ^a   Tan, Wei ^a   Luo, Mingjing ^a   Niu, Xiaodi ^a   Deng, Xuming ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; BACTERIA; BINDING ENERGY; BLOOD; CYTOLOGY; DISEASES; FREE ENERGY; MOLECULAR DYNAMICS; SELF ASSEMBLY;

CHANNEL FORMING; HAEMOLYSINS; HAEMOLYSIS; HEMOLYTIC ACTIVITY; OROXYLIN A; S. AUREUS; SELF-ASSEMBLING; STAPHYLOCOCCUS AUREUS; TRANS-MEMBRANE PORES; Α-HEMOLYSIN;

MONOMERS;

ALPHA HEMOLYSIN; ANTIINFECTIVE AGENT; BINDING PROTEIN; DEOXYCHOLIC ACID; MONOMER; OROXYLIN A;

ARTICLE; BACTERIAL STRAIN; CATALYSIS; CELL DEATH; CELL MEMBRANE; COCULTURE; CONFORMATIONAL TRANSITION; CYTOLYSIS; HEMOLYSIS; HOST CELL; LUNG ALVEOLUS EPITHELIUM; MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; PATHOGENESIS; SIMULATION; STAPHYLOCOCCAL PNEUMONIA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

EID: 84873509636     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002869     Document Type: Article

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