Insights Into the Enzymatic Mechanism of 6-Phosphogluconolactonase from Trypanosoma brucei Using Structural Data and Molecular Dynamics Simulation

Journal of Molecular Biology

Volumn 388, Issue 5, 2009, Pages 1009-1021

  Duclert Savatier, Nathalie ^a   Poggi, Luisa ^a   Miclet, Emeric ^b   Lopes, Philippe ^a   Ouazzani, Jamal ^a   Chevalier, Nathalie ^c   Nilges, Michael ^a   Delarue, Marc ^a   Stoven, Véronique ^d  

^a CNRS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c DE DUVE INSTITUTE   (Belgium)

^d PSL RESEARCH UNIVERSITY   (France)

Author keywords

6 phosphogluconolactonase; crystal structure; enzymatic mechanism; molecular dynamics simulation; Trypanosoma brucei

Indexed keywords

6 PHOSPHOGLUCONOLACTONASE; PENTOSE PHOSPHATE; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME STRUCTURE; MOLECULAR DYNAMICS; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; SIMULATION; TRYPANOSOMA BRUCEI;

TRYPANOSOMA BRUCEI;

EID: 67349251957     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.03.063     Document Type: Article

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