Orphan GPCRs and Methods for Identifying Their Ligands

Methods in Enzymology

Volumn 514, Issue , 2012, Pages 33-44

  Yoshida, Morikatsu ^a   Miyazato, Mikiya ^a   Kangawa, Kenji ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Bioactive peptide; Bioinformatics; G protein chimeras; G protein coupled receptor; High throughput screening; Orphan receptor; Promiscuous G proteins; Reporter gene assay; Reverse pharmacology

Indexed keywords

CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GHRELIN; LIGAND; NEUROMEDIN S; NEUROMEDIN U; NEUROPEPTIDE;

BIOASSAY; BIOLOGY; CELL STRAIN HEK293; GENE VECTOR; GENETICS; HIGH THROUGHPUT SCREENING; HUMAN; METABOLISM; METHODOLOGY; REPORTER GENE; REVIEW;

BIOLOGICAL ASSAY; COMPUTATIONAL BIOLOGY; CYCLIC AMP; GENES, REPORTER; GENETIC VECTORS; GHRELIN; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGANDS; NEUROPEPTIDES; RECEPTORS, G-PROTEIN-COUPLED;

MLCS; MLOWN;

EID: 84873450605     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/B978-0-12-381272-8.00002-7     Document Type: Chapter

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