Reactive oxygen species H2O2 and OH, but not O 2- promote oridonin-induced phagocytosis of apoptotic cells by human histocytic lymphoma U937 cells

International Immunopharmacology

Volumn 15, Issue 2, 2013, Pages 414-423

  Zang, Linghe ^a   He, Hao ^a   Xu, Qian ^a   Yu, Yang ^a   Zheng, Nan ^a   Liu, Weiwei ^a   Hayashi, Toshihiko ^a   Tashiro, Shin Ichi ^b   Onodera, Satoshi ^b   Ikejima, Takashi ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Autophagy; Mitochondria; Oridonin; Phagocytosis; Reactive oxygen species; U937 cell

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUTATHIONE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; ORIDONIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C GAMMA; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVATION; HISTIOCYTIC LYMPHOMA; HUMAN; HUMAN CELL; LYMPHOMA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PHAGOCYTOSIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; APOPTOSIS; AUTOPHAGY; DITERPENES, KAURANE; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LYMPHOMA, LARGE B-CELL, DIFFUSE; MAP KINASE SIGNALING SYSTEM; PHAGOCYTOSIS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOLIPASE C GAMMA; RAF KINASES; RAS PROTEINS; REACTIVE OXYGEN SPECIES; U937 CELLS;

EID: 84873435725     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.01.004     Document Type: Article

References (39)

1. M.R. Elliott, and K.S. Ravichandran Clearance of apoptotic cells: implications in health and disease J Cell Biol 189 2010 1059 1070
2. C.D. Gregory, and J.D. Pound Cell death in the neighbourhood: direct microenvironmental effects of apoptosis in normal and neoplastic tissues J Pathol 223 2011 177 194
3. L.E. Munoz, K. Lauber, M. Schiller, A.A. Manfredi, and M. Herrmann The role of defective clearance of apoptotic cells in systemic autoimmunity Nat Rev Rheumatol 6 2010 280 289
4. R.S. Flannagan, G. Cosio, and S. Grinstein Antimicrobial mechanisms of phagocytes and bacterial evasion strategies Nat Rev Microbiol 7 2009 355 366
5. R.F. Sheppard, M.R. Kelher, E.E. Moore, N.J. McLaughlin, A. Banerjee, and C.C. Silliman Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation J Leukoc Biol 78 2005 1025 1042
6. J. Yu, M. Weïwer, R.J. Linhardt, and J.S. Dordick The role of the methoxyphenolapocynin, a vascular NADPH oxidase inhibitor, as a chemopreventative agent in the potential treatment of cardiovascular diseases Curr Vasc Pharmacol 6 2008 204 217
7. M.P. Murphy How mitochondria produce reactive oxygen species Biochem J 417 2009 1 13
8. G.J. Burton, and E. Jauniaux Oxidative stress Best Pract Res Clin Obstet Gynaecol 25 2011 287 299
9. G.Y. Lam, J. Huang, and J.H. Brumell The many roles of NOX2 NADPH oxidase-derived ROS in immunity Semin Immunopathol 32 2010 415 430
10. D. Park, C.Z. Han, M.R. Elliott, J.M. Kinchen, P.C. Trampont, and S. Das Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein Nature 477 2011 220 224
11. J. Lee, S. Giordano, and J. Zhang Autophagy, mitochondria and oxidative stress: cross-talk and redox signaling Biochem J 441 2012 523 540
12. Q. Jiang, D.A. Griffin, D.F. Barofsky, and J.K. Hurst Intraphagosomal chlorination dynamics and yields determined using unique fluorescent bacterial mimics Chem Res Toxicol 10 1997 1080 1089
13. W.M. Nauseef Contributions of myeloperoxidase to proinflammatory events: more than an antimicrobial system Int J Hematol 74 2001 125 133
14. M.T. Sorbara, and S.E. Girardin Mitochondrial ROS fuel the inflammasome Cell Res 21 2011 558 560
15. X. Zeng, and C.R. Carlin Host cell autophagy modulates early stages of adenovirus infections in airway epithelial cells J Virol 12 2012 [Epub ahead of print]
16. L.H. Zang, Q. Xu, Y.C. Ye, X. Li, Y.Q. Liu, and T. Ikejima Autophagy enhanced phagocytosis of apoptotic cells by oridonin-treated human histocytic lymphoma U937 cells Arch Biochem Biophys 518 2012 31 41
17. Q. Wang, B. Liang, N.A. Shirwany, and M.H. Zou 2-Deoxy-d-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase PLoS One 6 2011 e17234
18. E.E. Essick, and F. Sam Oxidative stress and autophagy in cardiac disease, neurological disorders, aging and cancer Oxid Med Cell Longev 3 2010 168 177
19. T. Ikezoe, S.S. Chen, X.J. Tong, D. Heber, H. Taguchi, and H.P. Koeffler Int J Oncol 23 2003 1187 1193
20. Y. Cheng, F. Qiu, and T. Ikejima Molecular mechanisms of oridonin-induced apoptosis and autophagy in murine fibrosarcoma L929 cells Autophagy 5 2009 430 431
21. Y.Q. Liu, S. You, S.I. Tashiro, S. Onodera, and T. Ikejima Activation of phosphoinositide 3-kinase, protein kinase C, and extracellular signal-regulated kinase is required for oridonin-enhanced phagocytosis of apoptotic bodies in human macrophage-like U937 cells J Pharmacol Sci 98 2005 361 371
22. Y.Q. Liu, S. You, S.I. Tashiro, S. Onodera, and T. Ikejima Roles of Ras and extracellular signal-regulated kinase-dependent IκBα degradation in oridonin-enhanced phagocytosis of apoptotic cells by human macrophage-like U937 cells Int Immunopharmacol 6 2006 260 268
23. Y. Xu, Y. Xue, Y. Wang, D.C. Feng, S.T. Lin, and L.Y. Xu Multiple-modulation effects of oridonin on the production of proinflammatory cytokines and neurotrophic factors in LPS-activated microglia Int Immunopharmacol 9 2009 360 365
24. T. Gatsinzi, and K. Iverfeldt Sensitization to TRAIL-induced apoptosis in human neuroblastoma SK-N-AS cells by NF-κB inhibitors is dependent on reactive oxygen species (ROS) J Neurooncol 104 2011 459 472
25. H.J. Wang, Y.Y. Jiang, X.F. Wei, H. Huang, S.I. Tashiro, and S. Onodera Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells Free Radic Res 44 2010 90 100
26. S.M. Fan, L.H. Li, S.G. Chen, Y. Yu, M. Qi, and T. Ikejima Silibinin induced-autophagic and apoptotic death is associated with an increase in reactive oxygen and nitrogen species in HeLa cells Free Radic Res 45 2011 11 12
27. J. Yang, L.J. Wu, S.I. Tashiro, S. Onodera, and T. Ikejima Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells Free Radic Res 42 2008 492 504
28. B.B. Liu, P.F. Yang, Y.C. Ye, Y. Zhou, L.Z. Li, and T. Ikejima Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells Free Radic Res 45 2011 835 847
29. R. Zeng, Y. Chen, S. Zhao, and G.H. Cui Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1 Acta Pharmacol Sin 33 2012 91 100
30. J. Yang, L.J. Wu, S.I. Tashiro, S. Onodera, and T. Ikejima Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma HeLa cells Free Radic Res 44 2010 792 802
31. C. de Duve, and R. Wattiaux Functions of lysosomes Annu Rev Physiol 28 1966 435 492
32. R. Castino, I. Fiorentino, M. Cagnin, A. Giovia, and C. Isidoro Chelation of lysosomal iron protects dopaminergic SH-SY5Y neuroblastoma cells from hydrogen peroxide toxicity by precluding autophagy and Akt dephosphorylation Toxicol Sci 123 2011 523 541
33. A.P. West, I.E. Brodsky, C. Rahner, D.K. Woo, H. Erdjument-Bromage, and P. Tempst TLR signaling augments macrophage bactericidal activity through mitochondrial ROS Nature 472 2011 476 480
34. Y. Chen, and S.B. Gibson Is mitochondrial generation of reactive oxygen species a trigger for autophagy? Autophagy 4 2008 246 248
35. J. Yang, L.J. Wu, S.I. Tashiro, S. Onodera, and T. Ikejima Critical roles of reactive oxygen species in mitochondrial permeability transition in mediating evodiamine-induced human melanoma A375-S2 cell apoptosis Free Radic Res 41 2007 1099 1108
36. F.B. Chekeni, M.R. Elliott, J.K. Sandilos, S.F. Walk, J.M. Kinchen, and E.R. Lazarowski Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis Nature 467 2010 863 867
37. Y.C. Chuang, W.H. Su, H.Y. Lei, Y.S. Lin, H.S. Liu, and C.P. Chang Macrophage migration inhibitory factor induces autophagy via reactive oxygen species generation PLoS One 7 2012 e37613
38. T.L. Schmitt, H. Klein, and W. Dröge Hydrogen peroxide inhibits activity of the IGF-1 receptor kinase Redox Rep 11 2006 105 109
39. 2-mediated cell survival in silibinin-treated human melanoma A375-S2 cells via IGF-1R-PI3K-Akt and IGF-1R-PLC γ-PKC pathways Eur J Pharmacol 668 2011 78 87