Roles of Ras and extracellular signal-regulated kinase-dependent IκBα degradation in oridonin-enhanced phagocytosis of apoptotic cells by human macrophage-like U937 cells

International Immunopharmacology

Volumn 6, Issue 2, 2006, Pages 260-268

  Liu, Yan Qiu ^a   You, Song ^a   Tashiro, Shin Ichi ^b   Onodera, Satoshi ^b   Ikejima, Takashi ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Extracellular signal regulated kinase; I B ; IL 1 ; Oridonin; Phagocytosis; Ras

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; I KAPPA B; I KAPPA B ALPHA; MANUMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; ORIDONIN; PROTEASOME INHIBITOR; PROTEIN INHIBITOR; PYRROLIDINE DITHIOCARBAMATE; RAF PROTEIN; RAS PROTEIN; STRESS ACTIVATED PROTEIN KINASE INHIBITOR;

APOPTOSIS; ARTICLE; CHINESE HERB; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; MOLECULAR INTERACTION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; BLOTTING, WESTERN; DITERPENES; DITERPENES, KAURANE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; GENES, RAS; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-1; LEUPEPTINS; MACROPHAGES; PHAGOCYTOSIS; POLYENES; POLYUNSATURATED ALKAMIDES; PROLINE; PROTO-ONCOGENE PROTEINS C-RAF; RAS PROTEINS; THIOCARBAMATES; U937 CELLS;

EID: 30144433188     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2005.08.013     Document Type: Article

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