Global remodeling of the vascular stem cell niche in bone marrow of diabetic patients: Implication of the microRNA-155/FOXO3a signaling pathway

Circulation Research

Volumn 112, Issue 3, 2013, Pages 510-522

  Spinetti, Gaia ^b   Cordella, Daniela ^b   Fortunato, Orazio ^b   Sangalli, Elena ^b   Losa, Sergio ^b   Gotti, Ambra ^b   Carnelli, Franco ^b   Rosa, Francesco ^b   Riboldi, Stefano ^b,c   Sessa, Fausto ^d   Avolio, Elisa ^a,e   Beltrami, Antonio Paolo ^e   Emanueli, Constanza ^a   Madeddu, Paolo ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b IRCCS MULTIMEDICA   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

^d UNIVERSITY OF INSUBRIA   (Italy)

^e UNIVERSITY OF UDINE   (Italy)

Author keywords

bone marrow; diabetes mellitus type 2; macroangiopathy; microangiopathy; stem cells

Indexed keywords

CD34 ANTIGEN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLUCOSE; MICRORNA 155; TRANSCRIPTION FACTOR FKHRL1;

APOPTOSIS; ARTICLE; CELL COMPOSITION; CELL LINEAGE; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; CRITICAL LIMB ISCHEMIA; DIABETIC MICROANGIOPATHY; DIABETIC PATIENT; DOWN REGULATION; ENDOTHELIAL PROGENITOR CELL; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; HEMATOPOIETIC STEM CELL; HIP ARTHROPLASTY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIMB AMPUTATION; LIPID STORAGE; MAJOR CLINICAL STUDY; MICROVASCULATURE; MORPHOMETRICS; NON INSULIN DEPENDENT DIABETES MELLITUS; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL NICHE; UPREGULATION;

ADIPOSE TISSUE; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD34; APOPTOSIS; BIOLOGICAL MARKERS; BONE MARROW CELLS; BONE MARROW EXAMINATION; CASE-CONTROL STUDIES; CELL LINEAGE; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; ENDOTHELIAL CELLS; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; ISCHEMIA; MALE; MICRORNAS; MICROVESSELS; MIDDLE AGED; PERIPHERAL ARTERIAL DISEASE; SIGNAL TRANSDUCTION; STEM CELL NICHE; TRANSFECTION;

EID: 84873410324     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.300598     Document Type: Article

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