Diabetic stem-cell "mobilopathy"

New England Journal of Medicine

Volumn 365, Issue 26, 2011, Pages 2536-2538

  DiPersio, John F ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; GRANULOCYTE COLONY STIMULATING FACTOR; NERVE CELL ADHESION MOLECULE; NESTIN; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1; VASCULAR CELL ADHESION MOLECULE 1; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ARTICLE; CD34 SELECTION; CELL TRANSPORT; CELLULAR DISTRIBUTION; DIABETES MELLITUS; DISEASE ASSOCIATION; DOWN REGULATION; DRUG MECHANISM; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMOBILIZED CELL; LYMPHOMA; MICROENVIRONMENT; MOBILOPATHY; MYELOMA; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RISK REDUCTION; STEM CELL MOBILIZATION; ANIMAL; HUMAN; METHODOLOGY; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; CHEMOKINE CXCL12; DIABETES MELLITUS; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; MICE;

EID: 84855412101     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcibr1112347     Document Type: Article

References (5)

1. Pusic I, Jiang SY, Landua S, et al. Impact of mobilization and remobilization strategies on achieving sufficient stem cell yields for autologous transplantation. Biol Blood Marrow Transplant 2008;14:1045-56.
2. DiPersio JF, Micallef IN, Stiff PJ, et al. Phase III prospective randomized double-blind placebo-controlled trial of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte colony-stimulating factor for autologous stem-cell mobilization and transplantation for patients with non-Hodgkin's lymphoma. J Clin Oncol 2009;27:4767-73.
3. Sugiyama T, Kohara H, Noda M, Nagasawa T. Maintenance of hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches. Immunity 2006;25:977-88. (Pubitemid 44894948)
4. Méndez-Ferrer S, Michurina TV, Ferraro F, et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature 2010;466:829-34.
5. Ferraro F, Lymperi S, Mendez-Ferrer S, et al. Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Sci Transl Med 2011;3(104):104ra101.