Ocular surface extracellular DNA and nuclease activity imbalance: A new paradigm for inflammation in dry eye disease

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 13, 2012, Pages 8253-8263

  Sonawane, Snehal ^a   Khanolkar, Vishakha ^a   Namavari, Abed ^a   Chaudhary, Shweta ^a   Gandhi, Sonal ^a   Tibrewal, Sapna ^a   Jassim, Sarmad H ^a   Shaheen, Brittany ^a   Hallak, Joelle ^a   Horner, John H ^b   Newcomb, Martin ^b   Sarkar, Joy ^a   Jain, Sandeep ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; DNA; EXTRACELLULAR DNA; INTERFERON; INTERLEUKIN 6; MYELOID DIFFERENTIATION FACTOR 88; NUCLEASE; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CONFOCAL MICROSCOPY; CONJUNCTIVA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRY EYE; ENZYME ACTIVITY; EYE INFLAMMATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LACRIMAL FLUID; LASER CAPTURE MICRODISSECTION; MAJOR CLINICAL STUDY; NEUTROPHIL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TEAR FILM;

ANTIMICROBIAL CATIONIC PEPTIDES; CONJUNCTIVA; DEOXYRIBONUCLEASE I; DNA; DRY EYE SYNDROMES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION; HISTONES; HUMANS; LEUKOCYTE ELASTASE; LIPOCALIN 1; MICROSCOPY, CONFOCAL; NEUTROPHILS; POLYMERASE CHAIN REACTION; SALIVA; SIGNAL TRANSDUCTION; TEARS;

EID: 84873390383     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-10430     Document Type: Article

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