Polymorphonuclear leukocyte cells and elastase in tears

Current Eye Research

Volumn 16, Issue 8, 1997, Pages 810-819

  Sakata, Miki ^a   Sack, Robert A ^a,b   Sathe, Sonal ^a   Holden, Brien ^b   Beaton, Ann R ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Elastase; Human; Polymorphonuclear (PMN) cells; Protease; Tears; Zymography

Indexed keywords

ANTIBODY; CASEIN; ELASTASE; PLASMIN; PLASMINOGEN;

ANTIGENICITY; ARTICLE; CENTRIFUGATION; CYTOCHEMISTRY; DEGRANULATION; ENZYME ACTIVATION; EPITHELIUM; EYELID CLOSURE; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; LACRIMAL FLUID; MALE; MICROCIRCULATION; MOLECULAR WEIGHT; NEUTROPHIL; NORMAL HUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SAMPLING;

ADOLESCENT; ADULT; BLINKING; BLOTTING, WESTERN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMANS; LEUKOCYTE ELASTASE; MALE; MIDDLE AGED; NEUTROPHILS; PLASMIN; PLASMINOGEN; TEARS;

EID: 0030808360     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.16.8.810.8992     Document Type: Article

References (50)

1. Tsung, P. K. and Holly, F. J. (1981) Protease activities in human tears. Curr. Eye Res. 1, 351-355.
2. Van Setten, G. B., Stephans, R., Tervo, T., Salonen, E. M., Tarkkanen, A. and Vaheri, A. (1990) Effects of the Schirmer test on the fibrolytic system in the tear fluid. Exp. Eye Res. 50, 135-141.
3. Tervo, T., Salonen, E. M., Vaheri, A., Immonen, L., Van Setten, G. B., Himberg, J. J. and Tarkkanen, A. (1988) Elevation of tear fluid plasmin in corneal disease. Acta Ophthalmol. (Copenh.), 66, 393-399.
4. Berman, M., Leary, R. and Gage, J. (1980) Evidence for a role of the plasminogen activator-plasmin system in corneal ulceration. Invest. Ophthalmol. Vis. Sci. 19, 1204-1221.
5. Punyicki, M., Berta, A. and Tözser, J. (1988) Study of neutral proteinases of human tear samples using gels containing copolymerized substrates. Clin. Chem. Enzym. Comms. 1, 115-124.
6. Salonen, E. M., Tervo, T., Törma, E., Tarkkanen, A. and Vaheri, A. (1987) Plasmin in tear fluid of patients with corneal ulcers: basis for a new therapy. Acta Ophthalmologica, 65, 3-12.
7. Van Setten, G. B., Salonen, E. M., Vaheri, A., Beuerman, R. W., Hietanen, J., Tarkkanen, A. and Tervo, T. (1989) Plasmin and plasminogen activator activities in tear fluid during corneal wound healing after anterior keratectomy. Curr. Eye Res. 8, 1293-1298.
8. Berman, M. (1989) The pathogenesis of corneal epithelial defects. (Review). Acta Ophthalmologica-Supplement, 192, 55-64.
9. Wang, H. M., Berman, M. and Law, M. (1985) Latent and active plasminogen activator in corneal ulceration. Invest. Ophthalmol. Vis. Sci. 26, 511-524.
10. Tervo, T., Tervo, K., Van Setten, G. B., Virtanen, I. and Tarkkanen, A. (1989) Plasminogen activator and its inhibitor in the experimental corneal wound. Exp. Eye Res. 48, 445-449.
11. Berta, A., Tözser, J. and Holly, F. J. (1990) Determination of plasminogen activator activities in normal and pathological human tears: the significance of tear plasminogen activators in the inflammatory and traumatic lesions of the cornea and the conjunctiva. Acta Ophthalmologica, 68, 508-514.
12. Tözser, J., Berta, A. and Punyiczki, M. (1989) Plasminogen activator activity and plasminogen independent amidolytic activity in tear fluid from healthy persons and patients with anterior segment inflammation. Clin. Chim. Acta, 183, 323-331.
13. Berman, M., Manseau, E., Law, M. and Aiken, D. (1983) Ulceration is correlated with degradation of fibrin and fibronectin at the corneal surface. Invest. Ophthalmol. Vis. Sci. 24, 1358-1366.
14. Liotta, L. A., Goldfarb, R. H., Brundage, R., Siegel, G. P., Terranova, V and Garbisa, S. (1981) Effect of plasmin activator (urokinase), plasmin and thrombin on glycoprotein and collagenous components of basement membrane. Cancer Res. 41, 4229-4236.
15. Twining, S. S., Kirschner, S. E., Mahnke, L. A. and Frank, D. W. (1993) Effect of Pseudomonasa eruginosa elastase, alkaline protease, and exotoxin A on corneal proteinases and proteins. Invest. Ophthalmol. Vis. Sci. 34, 2699-2712.
16. Itoh, Y. and Nagase, H. (1995) Preferential inactivation of tissue inhibitor of metalloprotease-1 that is bound to the precursor of matrix metalloproteinase-9 (progelatinase B) by human neutrophil elastase. J. Biol. Chem. 270, 16518-16521.
17. Tervo, T. and Van Setten, G. B. (1989) Aprotinin for inhibition of plasmin on the ocular surface: principles and clinical observations. In Healing Processes of the Cornea (Eds. Beuerman, R. W., Crosson, C. E. and Kaufman, H. E.). Pp. 151-160. Portfolio Publishing Co., Woodlands, TX.
18. Cejková, J., Lojda, Z., Salonen, E. M. and Vaheri, A. (1989) Histochemical study of alkali-burned rabbit anterior eye segment in which severe lesions were prevented by aprotinin treatment. Histochemistry, 92, 441-448.
19. Tervo, T., Honkanen, N., Van Setten, G. B., Virtanen, T., Tarkkanen, A. and Harkönen, M. (1994) A rapid fluorometric assay for tear fluid plasmin activity. Cornea, 13, 148-155.
20. Virtanen, T., Honkanen, N., Harkönen, M., Tarkkanen, A. and Tervo, T. (1994) Elevation of tear fluid plasmin activity of contact lens wearers studied with a rapid fluorometric assay. Cornea, 14, 210-213.
21. Van Setten, G. B., Tervo, T., Andersson, R., Perheentupa, J. and Tarkkanen, A. (1990) Plasmin and epidermal growth factor in the tear fluid of contact lens wearers: effect of wearing different types of contact lenses and association with clinical findings. Ophthalmic Res. 22, 233-240.
22. Vaanus, A., Sweeney, F., Holden, B. A., Sapyska, E., Salonen, E. M. and Vaheri, A. (1992) Tear plasmin activity with contact lens wear. Curr. Eye Res. 11, 243-251.
23. Tan, K. O., Sack, R. A., Holden, B. A. and Swarbrick, H. A. (1993) Temporal sequence of changes in tear film composition during sleep. Curr. Eye Res. 12, 1001-1007.
24. Cejková, J., Lojda, Z., Vacik, J., Digenis, G. A. and Dropcová, S. (1992) Histochemical changes in the rabbit cornea and plasmin activity in the tear fluid during contact lens wear: favorable influence of protease inhibitors (aprotinin, PC5, elastatinal). Histochemistry, 97, 69-76.
25. Chalupa, E., Swarbrick, H. A., Holden, B. A. and Sjostrand, J. (1987) Severe corneal infections associated with contact lens wear. Ophthalmology, 94, 17-22.
26. Hamdi, H. K., Berjis, F., Brown, D. J. and Kenney, M. C. (1995) Proteinase activity in normal tears: male-female dimorphism. Curr. Eye Res. 14, 1081-1086.
27. van Haeringen, N. J. and Glasius, E. (1976) The origin of some enzymes in tear fluid, determined by comparative investigation with two collection methods. Exp. Eye Res. 22, 267-272.
28. Berta, A. (1986) Standardization of tear protein determinations: the effects of sampling, flow rate, and vascular permeability. In The Preocular Tear Film in Health, Disease and Contact Lens Wear (Ed. Holly, F. J.). Pp. 418-433. Dry Eye Institute, Lubbock, TX.
29. Berta, A. (1983) Collection of tear fluid samples with or without stimulation. Am. J. Ophthalmol. 96, 115-116.
30. Stuchell, R. N., Feldman, J. J., Farris, R. L. and Mandel, I. D. (1984) The effect of collection technique on tear composition. Invest. Ophthalmol. Vis. Sci. 25, 374-377.
31. Sack, R. A., Tan, K. O. and Tan, A. (1992) Diurnal tear cycle: evidence for a nocturnal inflammatory constitutive tear fluid. Invest. Ophthalmol Vis. Sci. 33, 626-640.
32. Kowal, K. and Weinstein, A. (1994) Western blot band intensity analysis: application to the diagnosis of Lyme arthritis. Arthritis and Rheumatism, 37, 1206-1211.
33. Velleman, S. G. (1995) Quantifying immunoblots with digital scanner. Bio Techniques, 18, 1056-1058.
34. Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
35. Heussen, C. and Dowdle, E. B. (1980) Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Analytical Biochem. 102, 196-202.
36. Fernandez-Resa, P., Mia, E. and Quesada, A. R. (1995) Enhanced detection of casein zymography of matrix metalloproteinases. Analytical Biochem. 224, 434-435.
37. Tschesche, H., Engelbrecht, S. and Wenzel, H. R. (1984) Leukocyte elastase. In Methods of Enzymatic Analysis, Vol. V, 3d Ed. (Bermeyer, H. U.). Pp. 176-184. Weinheim Publishers, Deerfield Beach, FL.
38. Tschesche, H., Knauper, V., Kramer, S., Micahelis, J., Oberhoff, R. and Reinke, H. (1992) Latent collagenase and gelatinase from human neutrophils and their activation. MATRIX, 1 (Suppl.), 245-255.
39. Sack, R. A., Bogart, B., Sathe, S., Beaton, A. and Lew, G. (1996) Characterization and origin of major non-reducing HMW tear sialoglycoproteins. (Abstract). Invest. Ophthalmol. Vis. Sci. 37 (Suppl.), S846.
40. Ren, H. and Wilson, G. (1996) Apoptosis in the corneal epithelium. Invest. Ophthalmol. Vis. Sci. 37, 1017-1025.
41. Prause, J. U. (1983) Serum albumin, serum antiproteases and polymorphonuclear leucocyte neutral collagenolytic protease in the tear fluid of patients with corneal ulcers. Acta Ophthalmol. (Copenh.), 61, 272-282.
42. Sack, R. A., Sathe, S., Hackworth, L. A., Willcox, M. D., Holden, B. A. and Morris, C. A. (1996) The effect of eye closure on protein and complement deposition on Group IV hydrogel contact lenses: relationship to tear flow dynamics. Curr. Eye Res. 15, 1092-1100.
43. Sack, R. A., Tan, K. O. and Tan, A. (1992) Diurnal tear cycle: evidence for a nocturnal inflammatory constitutive tear fluid. Invest. Ophthalmol. Vis. Sci. 33, 626-640.
44. Sack, R. A., Underwood, P. A., Tan, K. O., Sutherland, H. and Morris, C. A. (1993) Vitronectin: possible contribution to the closed-eye external host-defense mechanism. Ocular Immunol. Inflammation, 1, 327-336.
45. Thakur, A., Willcox, M. D. P., Morris, C. and Holden, B. A. (1996) Inflammatory mediators of tear fluid and their role in corneal inflammation. (Abstract). Invest. Ophthalmol. Vis. Sci. 37 (Suppl.), S234.
46. Birrer, P. (1995) Proteases and antiproteases in cystic fibrosis: pathogenetic considerations and therapeutic strategies [Review]. Respiration, 62 (Suppl. 1), 25-28.
47. Sepper, R., Konttinen, Y. T., Ingman, T. and Sorsa, T. (1995) Presence, activities, and molecular forms of cathepsin G, elastase, alpha 1-antitrypsin, and alpha 1-antichymotrypsin in bronchiectasis. J. Clin. Immunol. 15, 27-34.
48. Van-Seuninggen, I., Aubert, J. and Davril, M. (1992) Interaction between secretory leucocyte proteinase inhibitor and bronchial mucins or glycopeptides. Biochem. J. 281, 761-766.
49. Sathe, S., Sack, R. A., Beaton, A. and Holden, B. (1995) Diurnal variations in tear anti-protease activities. (Abstract). Invest. Ophthalmol. Vis. Sci. 36 (Suppl.), S996.
50. Sakata, M., Sack, R. A., Sathe, S., Beaton, A., Lew, G. and Holden, B. (1996) Proteases and antiproteases in the closed eye tears. (Abstract). Invest. Ophthalmol. Vis. Sci. 37 (Suppl.), S848.