Down-regulation of survivin by nemadipine-A sensitizes cancer cells to TRAIL-induced apoptosis

Biomolecules and Therapeutics

Volumn 21, Issue 1, 2013, Pages 29-34

  Park, Seong Ho ^a   Park, So Jung ^b,d   Kim, Joo Oh ^a   Shin, Ji Hyun ^b   Kim, Eun Sung ^b   Jo, Yoon Kyung ^b   Kim, Jae Sung ^c   Jin, Dong Hoon ^d,e   Hwang, Jung Jin ^d,e   Lee, Seung Jin ^d,e   Jeong, Seong Yun ^d,e   Lee, Chaeyoung ^f   Kim, Inki ^d,f   Cho, Dong Hyung ^b  

^a Hallym University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Korea Institute of Radiation and Medical Science   (South Korea)

^d Asan Medical Center   (South Korea)

^e Soongsil University   (South Korea)

^f University of Ulsan College of Medicine   (South Korea)

Author keywords

Cell death; H1299 cells; Nemadipine A; Sensitization; TRAIL

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CASPASE 3; CASPASE 8; DEATH RECEPTOR 4; DEATH RECEPTOR 5; GLUCOSE REGULATED PROTEIN 94; INITIATION FACTOR 2; NEMADIPINE A; PROTEIN KINASE B; SMALL INTERFERING RNA; SURVIVIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; DRUG SENSITIZATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; INTRACELLULAR SIGNALING; LUNG ADENOCARCINOMA; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

EID: 84873383072     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2012.088     Document Type: Article

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