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Journal of Organic Chemistry

Volumn 78, Issue 3, 2013, Pages 950-959

2,2-disubstituted 4-acylthio-3-oxobutyl groups as esterase- and thermolabile protecting groups of phosphodiesters

(5) Kiuru, Emilia a Ahmed, Zafar a Lönnberg, Harri a Beigelman, Leonid b Ora, Mikko a

a UNIVERSITY OF TURKU (Finland)

b AliosBiopharma (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL GROUPS; ACYL GROUP; BENZOYL GROUP; DEACYLATION; DEPROTECTION; GLUTATHIONES; HPLC-ESI MS; KETO GROUPS; MERCAPTO GROUPS; NON-ENZYMATIC; PHOSPHODIESTERS; PROTECTING GROUP; SPECTROSCOPIC MONITORING; STRUCTURAL CHARACTERIZATION; SULFUR ATOMS;

CHEMICAL BONDS; ELECTRONEGATIVITY; ENZYMES; SULFUR;

ESTERS;

2,2 DISUBSTITUTED 4 ACYLTHIO 3 OXOBUTYL; 4,4 DISUBSTITUTED 3 ACYLOXY 4,5 DIHYDROTHIOPHENE; ACETIC ACID DERIVATIVE; CHEMICAL COMPOUND; ESTERASE; GLUTATHIONE; PHOSPHODIESTERASE; PHOSPHOTRIESTERASE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; DEACYLATION; DEPROTECTION REACTION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDRATION; PH; PROTON NUCLEAR MAGNETIC RESONANCE;

CYCLIZATION; ESTERASES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; ORGANOPHOSPHONATES; PHOSPHATES;

EID: 84873376184 PISSN: 00223263 EISSN: 15206904 Source Type: Journal
DOI: 10.1021/jo302421u Document Type: Article

Times cited : (23)

References (29)

1
- 43049112098
- Hecker, S. J.; Erion, M. D. J. Med. Chem. 2008, 51, 2328-2345
- (2008) J. Med. Chem. , vol.51 , pp. 2328-2345
- Hecker, S.J.¹ Erion, M.D.²

2
- 33845333328
- Poijärvi-Virta, P.; Lönnberg, H. Curr. Med. Chem. 2006, 13, 3441-3465
- (2006) Curr. Med. Chem. , vol.13 , pp. 3441-3465
- Poijärvi-Virta, P.¹ Lönnberg, H.²

3
- 0027943194
- Farquhar, D.; Khan, S.; Srivastva, D. N.; Saunders, P. P. J. Med. Chem. 1994, 37, 3902-3909
- (1994) J. Med. Chem. , vol.37 , pp. 3902-3909
- Farquhar, D.¹ Khan, S.² Srivastva, D.N.³ Saunders, P.P.⁴

4
- 85046173566
- Armirilli, M. N.; Kim, C. U.; Dougherty, J.; Mulato, A.; Oliyai, R.; Shaw, J.-P.; Cundy, K. C.; Bischofberger, N. Antiviral Chemother. 1997, 8, 557-564
- (1997) Antiviral Chemother. , vol.8 , pp. 557-564
- Armirilli, M.N.¹ Kim, C.U.² Dougherty, J.³ Mulato, A.⁴ Oliyai, R.⁵ Shaw, J.-P.⁶ Cundy, K.C.⁷ Bischofberger, N.⁸

5
- 0027722026
- Perigaud, C.; Gosselin, G.; Lefebvre, I.; Girardet, J. L.; Benzaria, S.; Barber, I.; Imbach, J. L. Bioorg. Med. Chem. Lett. 1993, 3, 2521-2526
- (1993) Bioorg. Med. Chem. Lett. , vol.3 , pp. 2521-2526
- Perigaud, C.¹ Gosselin, G.² Lefebvre, I.³ Girardet, J.L.⁴ Benzaria, S.⁵ Barber, I.⁶ Imbach, J.L.⁷

6
- 0001949924
- Glazier, A.; Kwong, C.; Rose, J.; Buckheit, R. Antiviral Res. 1992, 17 (Suppl. 1) 66
- (1992) Antiviral Res. , vol.17 , Issue.SUPPL. 1 , pp. 66
- Glazier, A.¹ Kwong, C.² Rose, J.³ Buckheit, R.⁴

7
- 27944497822
- Poijärvi, P.; Heinonen, P.; Virta., P.; Lönnberg, H. Bioconjugate Chem. 2005, 16, 1564-1571
- (2005) Bioconjugate Chem. , vol.16 , pp. 1564-1571
- Poijärvi, P.¹ Heinonen, P.² Virta, P.³ Lönnberg, H.⁴

8
- 9244263226
- Poijärvi, P.; Oivanen, M.; Lönnberg, H. Lett. Org. Chem. 2004, 1, 183-188
- (2004) Lett. Org. Chem. , vol.1 , pp. 183-188
- Poijärvi, P.¹ Oivanen, M.² Lönnberg, H.³

9
- 67650355514
- Ora, M.; Taherpour, S.; Linna, R.; Leisvuori, A.; Hietamaki, E.; Poijarvi-Virta, P.; Beigelman, L.; Lönnberg, H. J. Org. Chem. 2009, 74, 4992-5001
- (2009) J. Org. Chem. , vol.74 , pp. 4992-5001
- Ora, M.¹ Taherpour, S.² Linna, R.³ Leisvuori, A.⁴ Hietamaki, E.⁵ Poijarvi-Virta, P.⁶ Beigelman, L.⁷ Lönnberg, H.⁸

10
- 0029014710
- Farquhar, D.; Chen, R.; Khan, S. J. Med. Chem. 1995, 38, 488-495
- (1995) J. Med. Chem. , vol.38 , pp. 488-495
- Farquhar, D.¹ Chen, R.² Khan, S.³

11
- 0027284753
- McGuigan, C.; Pathirana, R. N.; Balzarini, J.; De Clercq, E. J. Med. Chem. 1993, 36, 1048-1052
- (1993) J. Med. Chem. , vol.36 , pp. 1048-1052
- McGuigan, C.¹ Pathirana, R.N.² Balzarini, J.³ De Clercq, E.⁴

12
- 0030896486
- McGuigan, C.; Camarasa, M.-J.; Egberink, H.; Hartmann, K.; Karlsson, A.; Perno, C. F.; Balzarini, J. Int. Antiviral News 1997, 5, 19-21
- (1997) Int. Antiviral News , vol.5 , pp. 19-21
- McGuigan, C.¹ Camarasa, M.-J.² Egberink, H.³ Hartmann, K.⁴ Karlsson, A.⁵ Perno, C.F.⁶ Balzarini, J.⁷

13
- 79951911261
- Kiuru, E.; Ora, M.; Beigelman, L.; Blatt, L.; Lönnberg, H. Chem. Biodivers 2011, 8, 266-286
- (2011) Chem. Biodivers , vol.8 , pp. 266-286
- Kiuru, E.¹ Ora, M.² Beigelman, L.³ Blatt, L.⁴ Lönnberg, H.⁵

14
- 84859788415
- Kiuru, E.; Ora, M.; Beigelman, L.; Blatt, L.; Lönnberg, H. Chem. Biodivers 2012, 9, 669-688
- (2012) Chem. Biodivers , vol.9 , pp. 669-688
- Kiuru, E.¹ Ora, M.² Beigelman, L.³ Blatt, L.⁴ Lönnberg, H.⁵

15
- 21344471386
- Grajkowski, A.; Pedras-Vasconcelos, J.; Wang, V.; Ausin, C.; Hess, S.; Verthelyi, D.; Beaucage, S. Nucleic Acids Res. 2005, 33, 3550-3560
- (2005) Nucleic Acids Res. , vol.33 , pp. 3550-3560
- Grajkowski, A.¹ Pedras-Vasconcelos, J.² Wang, V.³ Ausin, C.⁴ Hess, S.⁵ Verthelyi, D.⁶ Beaucage, S.⁷

16
- 33846935981
- Grajkowski, A.; Ausin, C.; Kauffman, J. S.; Snyder, J.; Hess, S.; Lloyd, J. R.; Beaucage, S. J. Org. Chem. 2007, 72, 805-815
- (2007) J. Org. Chem. , vol.72 , pp. 805-815
- Grajkowski, A.¹ Ausin, C.² Kauffman, J.S.³ Snyder, J.⁴ Hess, S.⁵ Lloyd, J.R.⁶ Beaucage, S.⁷

17
- 70549105974
- Ausin, C.; Kauffman, J. S.; Duff, R. J.; Shivaprasad, S.; Beaucage, S. L. Tetrahedron 2010, 66, 68-79
- (2010) Tetrahedron , vol.66 , pp. 68-79
- Ausin, C.¹ Kauffman, J.S.² Duff, R.J.³ Shivaprasad, S.⁴ Beaucage, S.L.⁵

18
- 58149097702
- Gisch, N.; Pertenbreiter, F.; Balzarini, J.; Meier, C. J. Med. Chem. 2008, 51, 8115-8123
- (2008) J. Med. Chem. , vol.51 , pp. 8115-8123
- Gisch, N.¹ Pertenbreiter, F.² Balzarini, J.³ Meier, C.⁴

19
- 56249132165
- Gisch, N.; Balzarini, J.; Meier, C. J. Med. Chem. 2008, 51, 6752-6760
- (2008) J. Med. Chem. , vol.51 , pp. 6752-6760
- Gisch, N.¹ Balzarini, J.² Meier, C.³

20
- 33947693161
- Ducho, C.; Görbig, U.; Jessel, S.; Gisch, N.; Balzarini, J.; Meier, C. J. Med. Chem. 2007, 50, 1335-1346
- (2007) J. Med. Chem. , vol.50 , pp. 1335-1346
- Ducho, C.¹ Görbig, U.² Jessel, S.³ Gisch, N.⁴ Balzarini, J.⁵ Meier, C.⁶

21
- 34147154785
- Gisch, N.; Balzarini, J.; Meier, C. J. Med. Chem. 2007, 50, 1658-1667
- (2007) J. Med. Chem. , vol.50 , pp. 1658-1667
- Gisch, N.¹ Balzarini, J.² Meier, C.³

22
- 0001674525
- Svendsen, A.; Boll, P. M. Tetrahedron 1973, 29, 4251-4258
- (1973) Tetrahedron , vol.29 , pp. 4251-4258
- Svendsen, A.¹ Boll, P.M.²

23
- 0030829742
- Guzaev, A.; Lönnberg, H. Synthesis 1997, 1281-1284
- (1997) Synthesis , pp. 1281-1284
- Guzaev, A.¹ Lönnberg, H.²

24
- 0028072493
- Boeykens, M.; De Kimpe, N.; Tehrani, K. A. J. Org. Chem. 1994, 59, 6973-6985
- (1994) J. Org. Chem. , vol.59 , pp. 6973-6985
- Boeykens, M.¹ De Kimpe, N.² Tehrani, K.A.³

25
- 79251502007
- Ora, M.; Mäntyvaara, A.; Lönnberg, H. Molecules 2011, 16, 552-566
- (2011) Molecules , vol.16 , pp. 552-566
- Ora, M.¹ Mäntyvaara, A.² Lönnberg, H.³

26
- 34248656969
- Jenkinson, S. F.; Jones, N. A.; Moussa, A.; Stewart, A. J.; Heinz, T.; Fleet, G. W. J. Tetrahedron Lett. 2007, 48, 4441-4444
- (2007) Tetrahedron Lett. , vol.48 , pp. 4441-4444
- Jenkinson, S.F.¹ Jones, N.A.² Moussa, A.³ Stewart, A.J.⁴ Heinz, T.⁵ Fleet, G.W.J.⁶

27
- 0035823872
- Yang, W.; Drueckhammer, D. G. J. Am. Chem. Soc. 2001, 123, 11004-11009
- (2001) J. Am. Chem. Soc. , vol.123 , pp. 11004-11009
- Yang, W.¹ Drueckhammer, D.G.²

28
- 1942487370
- Calvo, K. C.; Wang, X.; Koser, G. F. Nucleosides Nucleotides Nucleic Acids 2004, 23, 637-646
- (2004) Nucleosides Nucleotides Nucleic Acids , vol.23 , pp. 637-646
- Calvo, K.C.¹ Wang, X.² Koser, G.F.³

29
- 84873378180
- Leisvuori, A.; Ahmed, Z.; Ora, M.; Blatt, L.; Beigelman, L.; Lönnberg, H. ARKIVOC 2012, 5, 226-243
- (2012) ARKIVOC , vol.5 , pp. 226-243
- Leisvuori, A.¹ Ahmed, Z.² Ora, M.³ Blatt, L.⁴ Beigelman, L.⁵ Lönnberg, H.⁶

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