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Volumn 8, Issue 2, 2011, Pages 266-286

Synthesis and enzymatic deprotection of biodegradably protected dinucleoside-2′,5′-monophosphates: 3-(Acetyloxy)-2,2- bis(ethoxycarbonyl)propyl phosphoesters of 3′-O-(acyloxymethyl)adenylyl- 2′,5′-adenosines

(5) Kiuru, Emilia a Ora, Mikko a Beigelman, Leonid b Blatt, Lawrence b Lönnberg, Harri a

a UNIVERSITY OF TURKU (Finland)

b AliosBiopharma (United States)

Author keywords

Dinucleoside 2 ,5 monophosphates; Enzymatic deprotection; Nucleosides

Indexed keywords

3' O (ACYLOXYMETHYL)ADENYLYL 2',5' ADENOSINE DERIVATIVE; ADENOSINE DERIVATIVE; CARBOXYLESTERASE; DINUCLEOSIDE 2',5' MONOPHOSPHATE DERIVATIVE; DINUCLEOTIDE; METHYL GROUP; ORGANOPHOSPHATE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; BIODEGRADABILITY; CATALYSIS; DEPROTECTION REACTION; DIASTEREOISOMER; HYDROLYSIS; ISOMERIZATION; NUCLEIC ACID SYNTHESIS; PH; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TEMPERATURE;

ADENOSINE; ANIMALS; CARBOHYDRATE CONFORMATION; CARBOXYLESTERASE; DINUCLEOSIDE PHOSPHATES; HYDROGEN-ION CONCENTRATION; ISOMERISM; OLIGORIBONUCLEOTIDES; PHOSPHATES; PRODRUGS; SWINE;

EID: 79951911261 PISSN: 16121872 EISSN: 16121880 Source Type: Journal
DOI: 10.1002/cbdv.201000288 Document Type: Article

Times cited : (15)

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