Studies on enzyme-cleavable dialkoxymethyl-cycloSaligenyl-2′, 3′-dideoxy-2′,3′-didehydrothymidine monophosphates

Journal of Medicinal Chemistry

Volumn 51, Issue 21, 2008, Pages 6752-6760

  Gisch, Nicolas ^a   Balzarini, Jan ^b   Meier, Chris ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

3 DIACETOXYMETHYL 5 METHYL CYCLOSAL D4T MONOPHOSPHATE; 3 DIACETOXYMETHYL 5 TERT BUTYL CYCLOSAL D4T MONOPHOSPHATE; 3 FORMYL 5 METHYL CYCLOSAL D4T MONOPHOSPHATE; 3 FORMYL 5 TERT BUTYL CYCLOSAL D4T MONOPHOSPHATE; 5 DIACETOXYMETHYL 3 TERT BUTYL CYCLOSAL D4T MONOPHOSPHATE; 5 DIISOBUTYROXYMETHYL 3 METHYL CYCLOSAL D4T MONOPHOSPHATE; 5 DIISOBUTYROXYMETHYL 3 TERT BUTYL CYCLOSAL D4T MONOPHOSPHATE; 5 FORMYL 3 TERT BUTYL CYCLOSAL D4T MONOPHOSPHATE; ENZYME; METHYL GROUP; NUCLEOTIDE; THYMIDINE PHOSPHATE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; ATOM; DIASTEREOISOMER; HYDROLYSIS; SOLUBILITY; STRUCTURE ANALYSIS; X RAY ANALYSIS;

ALKYLATION; ANTI-HIV AGENTS; BENZYL ALCOHOLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIDEOXYNUCLEOTIDES; ENZYMES; HYDROLYSIS; METHYLATION; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STAVUDINE; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; X-RAY DIFFRACTION;

EID: 56249132165     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800853p     Document Type: Article

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