-
1
-
-
13144277688
-
-
Geneva, Switzerland: World Health Organization; 2003. Global Programme on Evidence for Health Policy Discussion Paper No. 54
-
Mathers CD, Bernard C, Iburg KM, Inoue M, Fat DM, Shibuya K, Stein C, Tomijima N, Xu H. Global Burden of Disease in 2002: data sources, methods and results. Geneva, Switzerland: World Health Organization; 2003. Global Programme on Evidence for Health Policy Discussion Paper No. 54.
-
Global Burden Of Disease In 2002: data sources, methods and results
-
-
Mathers, C.D.1
Bernard, C.2
Iburg, K.M.3
Inoue, M.4
Fat, D.M.5
Shibuya, K.6
Stein, C.7
Tomijima, N.8
Xu, H.9
-
3
-
-
0029947193
-
Association of chronic mucus hypersecretion with fev1 decline and chronic obstructive pulmonary disease morbidity. Copenhagen city heart study group
-
Vestbo J, Prescott E, Lange P. Association of chronic mucus hypersecretion with FEV1 decline and chronic obstructive pulmonary disease morbidity. Copenhagen City Heart Study Group. Am J Respir Crit Care Med 1996;153:1530-1535.
-
(1996)
Am J Respir Crit Care Med
, vol.153
, pp. 1530-1535
-
-
Vestbo, J.1
Prescott, E.2
Lange, P.3
-
4
-
-
64749104557
-
Initiatives bronchopneumopathie chronique obstructive scientific committee. Cough and sputum production are associated with frequent exacerbations and hospitalizations in copd subjects
-
Burgel PR, Nesme-Meyer P, Chanez P, Caillaud D, Carre P, Perez T, Roche N, Initiatives Bronchopneumopathie Chronique Obstructive Scientific Committee. Cough and sputum production are associated with frequent exacerbations and hospitalizations in COPD subjects. Chest 2009;135:975-982.
-
(2009)
Chest
, vol.135
, pp. 975-982
-
-
Burgel, P.R.1
Nesme-Meyer, P.2
Chanez, P.3
Caillaud, D.4
Carre, P.5
Perez, T.6
Roche, N.7
-
5
-
-
70349694402
-
Chronic bronchitis before age 50 years predicts incident airflow limitation and mortality risk
-
Guerra S, Sherrill DL, Venker C, Ceccato CM, Halonen M, Martinez FD. Chronic bronchitis before age 50 years predicts incident airflow limitation and mortality risk. Thorax 2009;64:894-900.
-
(2009)
Thorax
, vol.64
, pp. 894-900
-
-
Guerra, S.1
Sherrill, D.L.2
Venker, C.3
Ceccato, C.M.4
Halonen, M.5
Martinez, F.D.6
-
6
-
-
80052690031
-
The chronic bronchitic phenotype of copd: An analysis of the copdgene study
-
The COPDGene Investigators
-
Kim V, Han MK, Vance GB, Make BJ, Newell JD, Hokanson JE, Hersh CP, Stinson D, Silverman EK, Criner GJ; The COPDGene Investigators. The chronic bronchitic phenotype of COPD: an analysis of the COPDGene study. Chest 2011;140:626-633.
-
(2011)
Chest
, vol.140
, pp. 626-633
-
-
Kim, V.1
Han, M.K.2
Vance, G.B.3
Make, B.J.4
Newell, J.D.5
Hokanson, J.E.6
Hersh, C.P.7
Stinson, D.8
Silverman, E.K.9
Criner, G.J.10
-
7
-
-
0024406878
-
Chronic obstructive lung disease in copenhagen: Crosssectional epidemiological aspects
-
Lange P, Groth S, Nyboe J, Appleyard M, Mortensen J, Jensen G, Schnohr P. Chronic obstructive lung disease in Copenhagen: crosssectional epidemiological aspects. J Intern Med 1989;226:25-32.
-
(1989)
J Intern Med
, vol.226
, pp. 25-32
-
-
Lange, P.1
Groth, S.2
Nyboe, J.3
Appleyard, M.4
Mortensen, J.5
Jensen, G.6
Schnohr, P.7
-
8
-
-
0032745868
-
Increasing prevalence of asthma but not of chronic bronchitis in finland? Report from the finess-helsinki study
-
Pallasaho P, Lundback B, Laspa SL, Jonsson E, Kotaniemi J, Sovijarvi AR, Laitinen LA. Increasing prevalence of asthma but not of chronic bronchitis in Finland? Report from the FinEsS-Helsinki Study. Respir Med 1999;93:798-809.
-
(1999)
Respir Med
, vol.93
, pp. 798-809
-
-
Pallasaho, P.1
Lundback, B.2
Laspa, S.L.3
Jonsson, E.4
Kotaniemi, J.5
Sovijarvi, A.R.6
Laitinen, L.A.7
-
9
-
-
0347386288
-
Epidemiological study of chronic obstructive pulmonary disease in spain (iberpoc): Prevalence of chronic respiratory symptoms and airflow limitation
-
Sobradillo V, Miravitlles M, Jimenez CA, Gabriel R, Viejo JL, Masa JF, Fernandez-Fau L, Villasante C. Epidemiological study of chronic obstructive pulmonary disease in Spain (IBERPOC): prevalence of chronic respiratory symptoms and airflow limitation. Arch Bronconeumol 1999;35:159-166.
-
(1999)
Arch Bronconeumol
, vol.35
, pp. 159-166
-
-
Sobradillo, V.1
Miravitlles, M.2
Jimenez, C.A.3
Gabriel, R.4
Viejo, J.L.5
Masa, J.F.6
Fernandez-Fau, L.7
Villasante, C.8
-
10
-
-
0034035120
-
Airway obstruction in relation to symptoms in chronic respiratory disease-a nationally representative population study
-
von Hertzen L, Reunanen A, Impivaara O, Malkia E, Aromaa A. Airway obstruction in relation to symptoms in chronic respiratory disease-a nationally representative population study. Respir Med 2000;94:356-363.
-
(2000)
Respir Med
, vol.94
, pp. 356-363
-
-
Von Hertzen, L.1
Reunanen, A.2
Impivaara, O.3
Malkia, E.4
Aromaa, A.5
-
11
-
-
0034906052
-
Variations in the prevalence across countries of chronic bronchitis and smoking habits in young adults
-
European Community Respiratory Health Survey (ECRHS) Group S
-
Cerveri I, Accordini S, Verlato G, Corsico A, Zoia MC, Casali L, Burney P, de Marco R; European Community Respiratory Health Survey (ECRHS) Study Group. Variations in the prevalence across countries of chronic bronchitis and smoking habits in young adults. Eur Respir J 2001;18:85-92.
-
(2001)
Eur Respir J
, vol.18
, pp. 85-92
-
-
Cerveri, I.1
Accordini, S.2
Verlato, G.3
Corsico, A.4
Zoia, M.C.5
Casali, L.6
Burney, P.7
De Marco, R.8
-
12
-
-
17944368370
-
Determinants of cough in young adults participating in the european community respiratory health survey
-
Janson C, Chinn S, Jarvis D, Burney P. Determinants of cough in young adults participating in the European Community Respiratory Health Survey. Eur Respir J 2001;18:647-654.
-
(2001)
Eur Respir J
, vol.18
, pp. 647-654
-
-
Janson, C.1
Chinn, S.2
Jarvis, D.3
Burney, P.4
-
13
-
-
0036796532
-
Chronic bronchitis among french adults: High prevalence and underdiagnosis
-
Huchon GJ, Vergnenegre A, Neukirch F, Brami G, Roche N, Preux PM. Chronic bronchitis among French adults: high prevalence and underdiagnosis. Eur Respir J 2002;20:806-812.
-
(2002)
Eur Respir J
, vol.20
, pp. 806-812
-
-
Huchon, G.J.1
Vergnenegre, A.2
Neukirch, F.3
Brami, G.4
Roche, N.5
Preux, P.M.6
-
14
-
-
0345701470
-
Not 15 but 50% of smokers develop copd?-report from the obstructive lung disease in northern sweden studies
-
Obstructive Lung Disease in Northern Sweden Studies
-
Lundback B, Lindberg A, Lindstrom M, Ronmark E, Jonsson AC, Jonsson E, Larsson LG, Andersson S, Sandstrom T, Larsson K. Obstructive Lung Disease in Northern Sweden Studies. Not 15 but 50% of smokers develop COPD?-Report from the Obstructive Lung Disease in Northern Sweden Studies. Respir Med 2003;97:115-122.
-
(2003)
Respir Med
, vol.97
, pp. 115-122
-
-
Lundback, B.1
Lindberg, A.2
Lindstrom, M.3
Ronmark, E.4
Jonsson, A.C.5
Jonsson, E.6
Larsson, L.G.7
Andersson, S.8
Sandstrom, T.9
Larsson, K.10
-
15
-
-
33749362986
-
Chronic respiratory symptoms spirometry and knowledge of copd among general population
-
Miravitlles M, de la Roza C, Morera J, Montemayor T, Gobartt E, Martin A, Alvarez-Sala JL. Chronic respiratory symptoms, spirometry and knowledge of COPD among general population. Respir Med 2006;100:1973-1980.
-
(2006)
Respir Med
, vol.100
, pp. 1973-1980
-
-
Miravitlles, M.1
De La Roza, C.2
Morera, J.3
Montemayor, T.4
Gobartt, E.5
Martin, A.6
Alvarez-Sala, J.L.7
-
16
-
-
33846248798
-
Incidence of chronic obstructive pulmonary disease in a cohort of young adults according to the presence of chronic cough and phlegm
-
de Marco R, Accordini S, Cerveri I, Corsico A, Anto JM, Kunzli N, Janson C, Sunyer J, Jarvis D, Chinn S, et al. Incidence of chronic obstructive pulmonary disease in a cohort of young adults according to the presence of chronic cough and phlegm. Am J Respir Crit Care Med 2007;175:32-39.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 32-39
-
-
De Marco, R.1
Accordini, S.2
Cerveri, I.3
Corsico, A.4
Anto, J.M.5
Kunzli, N.6
Janson, C.7
Sunyer, J.8
Jarvis, D.9
Chinn, S.10
-
17
-
-
70349667504
-
Prevalence of copd in spain: Impact of undiagnosed copd on quality of life and daily life activities
-
Miravitlles M, Soriano JB, Garcia-Rio F, Munoz L, Duran-Tauleria E, Sanchez G, Sobradillo V, Ancochea J. Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities. Thorax 2009;64:863-868.
-
(2009)
Thorax
, vol.64
, pp. 863-868
-
-
Miravitlles, M.1
Soriano, J.B.2
Garcia-Rio, F.3
Munoz, L.4
Duran-Tauleria, E.5
Sanchez, G.6
Sobradillo, V.7
Ancochea, J.8
-
18
-
-
77954730879
-
Chronic mucus hypersecretion: Prevalence and risk factors in younger individuals
-
Harmsen L, Thomsen SF, Ingebrigtsen T, Steffensen IE, Skadhauge LR, Kyvik KO, Backer V. Chronic mucus hypersecretion: prevalence and risk factors in younger individuals. Int J Tuberc Lung Dis 2010;14:1052-1058.
-
(2010)
Int J Tuberc Lung Dis
, vol.14
, pp. 1052-1058
-
-
Harmsen, L.1
Thomsen, S.F.2
Ingebrigtsen, T.3
Steffensen, I.E.4
Skadhauge, L.R.5
Kyvik, K.O.6
Backer, V.7
-
19
-
-
84870645803
-
Non-obstructive chronic bronchitis in the copdgene cohort [abstract]
-
Martinez C, Chen Y, Kazerooni E, Murray S, Criner GJ, Curtis JL, Martinez FJ, Kim V, Han MK. Non-obstructive chronic bronchitis in the COPDGene cohort [abstract]. Am J Respir Crit Care Med 2012; 185:A6622.
-
(2012)
Am J Respir Crit Care Med
, vol.185
-
-
Martinez, C.1
Chen, Y.2
Kazerooni, E.3
Murray, S.4
Criner, G.J.5
Curtis, J.L.6
Martinez, F.J.7
Kim, V.8
Han, M.K.9
-
20
-
-
79551603829
-
Evaluation of copd longitudinally to identify predictive surrogate endpoints (eclipse) investigators. characterisation of copd heterogeneity in the eclipse cohort
-
Agusti A, Calverley PM, Celli B, Coxson HO, Edwards LD, Lomas DA, MacNee W, Miller BE, Rennard S, Silverman EK, et al, Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res 2010;11:122.
-
(2010)
Respir Res
, vol.11
, pp. 122
-
-
Agusti, A.1
Calverley, P.M.2
Celli, B.3
Coxson, H.O.4
Edwards, L.D.5
Lomas, D.A.6
MacNee, W.7
Miller, B.E.8
Rennard, S.9
Silverman, E.K.10
Et Al.11
-
21
-
-
84862491658
-
The chronic bronchitis phenotype in subjects with and without copd: The platino study
-
de Oca MM, Halbert RJ, Lopez MV, Perez-Padilla R, Talamo C, Moreno D, Muino A, Jardim JR, Valdivia G, Pertuze J, et al. The chronic bronchitis phenotype in subjects with and without COPD: the PLATINO study. Eur Respir J 2012;40:28-36.
-
(2012)
Eur Respir J
, vol.40
, pp. 28-36
-
-
De Oca, M.M.1
Halbert, R.J.2
Lopez, M.V.3
Perez-Padilla, R.4
Talamo, C.5
Moreno, D.6
Muino, A.7
Jardim, J.R.8
Valdivia, G.9
Pertuze, J.10
-
22
-
-
33750048426
-
Thirtyyear cumulative incidence of chronic bronchitis and copd in relation to 30-year pulmonary function and 40-year mortality: A follow-up in middle-aged rural men
-
Pelkonen M, Notkola IL, Nissinen A, Tukiainen H, Koskela H. Thirtyyear cumulative incidence of chronic bronchitis and COPD in relation to 30-year pulmonary function and 40-year mortality: a follow-up in middle-aged rural men. Chest 2006;130:1129-1137.
-
(2006)
Chest
, vol.130
, pp. 1129-1137
-
-
Pelkonen, M.1
Notkola, I.L.2
Nissinen, A.3
Tukiainen, H.4
Koskela, H.5
-
23
-
-
66649092768
-
-
American Lung Association. Washington, DC: Research and Program Services Division, Epidemiology and Statistics Unit, Americal Lung Association
-
American Lung Association. Trends in COPD (chronic bronchitis and emphysema): morbidity and mortality. Washington, DC: Research and Program Services Division, Epidemiology and Statistics Unit, Americal Lung Association; 2011.
-
(2011)
Trends in COPD (chronic bronchitis and emphysema): morbidity and mortality.
-
-
-
25
-
-
77957278202
-
Chronic obstructive pulmonary disease in the absence of chronic bronchitis in china
-
Lu M, Yao W, Zhong N, Zhou Y, Wang C, Chen P, Kang J, Huang S, Chen B, Wang C, et al. Chronic obstructive pulmonary disease in the absence of chronic bronchitis in China. Respirology 2010;15:1072-1078.
-
(2010)
Respirology
, vol.15
, pp. 1072-1078
-
-
Lu, M.1
Yao, W.2
Zhong, N.3
Zhou, Y.4
Wang, C.5
Chen, P.6
Kang, J.7
Huang, S.8
Chen, B.9
Wang, C.10
-
26
-
-
84870629633
-
Significance of chronic bronchitis in the copd crn azithromycin in copd study [abstract]
-
Han MK, Kim V, Martinez C, Curtis JL, Woodruff PG, Albert RK, Connett J, Criner GJ, Martinez FJ. Significance of chronic bronchitis in the COPD CRN Azithromycin in COPD Study [abstract]. Am J Respir Crit Care Med 2012;185:A3736.
-
(2012)
Am J Respir Crit Care Med
, vol.185
-
-
Han, M.K.1
Kim, V.2
Martinez, C.3
Curtis, J.L.4
Woodruff, P.G.5
Albert, R.K.6
Connett, J.7
Criner, G.J.8
Martinez, F.J.9
-
27
-
-
2442630608
-
Predictors of chronic bronchitis in south african adults
-
Ehrlich RI, White N, Norman R, Laubscher R, Steyn K, Lombard C, Bradshaw D. Predictors of chronic bronchitis in South African adults. Int J Tuberc Lung Dis 2004;8:369-376.
-
(2004)
Int J Tuberc Lung Dis
, vol.8
, pp. 369-376
-
-
Ehrlich, R.I.1
White, N.2
Norman, R.3
Laubscher, R.4
Steyn, K.5
Lombard, C.6
Bradshaw, D.7
-
28
-
-
33845497165
-
European respiratory society study on chronic obstructive pulmonary disease. Predictors of copd symptoms: Does the sex of the patient matter?
-
Watson L, Schouten JP, Lofdahl CG, Pride NB, Laitinen LA, Postma DS; European Respiratory Society Study on Chronic Obstructive Pulmonary Disease. Predictors of COPD symptoms: does the sex of the patient matter? Eur Respir J 2006;28:311-318.
-
(2006)
Eur Respir J
, vol.28
, pp. 311-318
-
-
Watson, L.1
Schouten, J.P.2
Lofdahl, C.G.3
Pride, N.B.4
Laitinen, L.A.5
Postma, D.S.6
-
30
-
-
0042380084
-
The occupational burden of chronic obstructive pulmonary disease
-
Trupin L, Earnest G, San Pedro M, Balmes JR, Eisner MD, Yelin E, Katz PP, Blanc PD. The occupational burden of chronic obstructive pulmonary disease. Eur Respir J 2003;22:462-469.
-
(2003)
Eur Respir J
, vol.22
, pp. 462-469
-
-
Trupin, L.1
Earnest, G.2
San Pedro, M.3
Balmes, J.R.4
Eisner, M.D.5
Yelin, E.6
Katz, P.P.7
Blanc, P.D.8
-
31
-
-
23744485729
-
Biological dust exposure in the workplace is a risk factor for chronic obstructive pulmonary disease
-
Matheson MC, Benke G, Raven J, Sim MR, Kromhout H, Vermeulen R, Johns DP, Walters EH, Abramson MJ. Biological dust exposure in the workplace is a risk factor for chronic obstructive pulmonary disease. Thorax 2005;60:645-651.
-
(2005)
Thorax
, vol.60
, pp. 645-651
-
-
Matheson, M.C.1
Benke, G.2
Raven, J.3
Sim, M.R.4
Kromhout, H.5
Vermeulen, R.6
Johns, D.P.7
Walters, E.H.8
Abramson, M.J.9
-
32
-
-
0022345212
-
Respiratory complications of gastroesophageal reflux
-
Barish CF, Wu WC, Castell DO. Respiratory complications of gastroesophageal reflux. Arch Intern Med 1985;145:1882-1888.
-
(1985)
Arch Intern Med
, vol.145
, pp. 1882-1888
-
-
Barish, C.F.1
Wu, W.C.2
Castell, D.O.3
-
33
-
-
0028850051
-
Chronic cough with a history of excessive sputum production. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy
-
Smyrnios NA, Irwin RS, Curley FJ. Chronic cough with a history of excessive sputum production. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy. Chest 1995;108:991-997.
-
(1995)
Chest
, vol.108
, pp. 991-997
-
-
Smyrnios, N.A.1
Irwin, R.S.2
Curley, F.J.3
-
34
-
-
0016426074
-
The bronchiolar epithelium in cigarette smokers. observations with the scanning electron microscope
-
Ebert RV, Terracio MJ. The bronchiolar epithelium in cigarette smokers. Observations with the scanning electron microscope. Am Rev Respir Dis 1975;111:4-11.
-
(1975)
Am Rev Respir Dis
, vol.111
, pp. 4-11
-
-
Ebert, R.V.1
Terracio, M.J.2
-
35
-
-
13544262442
-
Metalloproteinases mediate mucin 5ac expression by epidermal growth factor receptor activation
-
Deshmukh HS, Case LM, Wesselkamper SC, Borchers MT, Martin LD, Shertzer HG, Nadel JA, Leikauf GD. Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation. Am J Respir Crit Care Med 2005;171:305-314.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 305-314
-
-
Deshmukh, H.S.1
Case, L.M.2
Wesselkamper, S.C.3
Borchers, M.T.4
Martin, L.D.5
Shertzer, H.G.6
Nadel, J.A.7
Leikauf, G.D.8
-
36
-
-
24144490371
-
Acute and chronic airway responses to viral infection: Implications for asthma and chronic obstructive pulmonary disease
-
Holtzman MJ, Tyner JW, Kim EY, Lo MS, Patel AC, Shornick LP, Agapov E, Zhang Y. Acute and chronic airway responses to viral infection: implications for asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005;2:132-140.
-
(2005)
Proc Am Thorac Soc
, vol.2
, pp. 132-140
-
-
Holtzman, M.J.1
Tyner, J.W.2
Kim, E.Y.3
Lo, M.S.4
Patel, A.C.5
Shornick, L.P.6
Agapov, E.7
Zhang, Y.8
-
37
-
-
8544250584
-
Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium
-
Burgel PR, Nadel JA. Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium. Thorax 2004;59:992-996.
-
(2004)
Thorax
, vol.59
, pp. 992-996
-
-
Burgel, P.R.1
Nadel, J.A.2
-
38
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004;350:2645-2653.
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
Woods, R.4
Elliott, W.M.5
Buzatu, L.6
Cherniack, R.M.7
Rogers, R.M.8
Sciurba, F.C.9
Coxson, H.O.10
-
39
-
-
0028920130
-
Ciliary abnormalities in bronchial epithelium of smokers, exsmokers, and nonsmokers
-
Verra F, Escudier E, Lebargy F, Bernaudin JF, De Cremoux H, Bignon J. Ciliary abnormalities in bronchial epithelium of smokers, exsmokers, and nonsmokers. Am J Respir Crit Care Med 1995;151: 630-634.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 630-634
-
-
Verra, F.1
Escudier, E.2
Lebargy, F.3
Bernaudin, J.F.4
De Cremoux, H.5
Bignon, J.6
-
40
-
-
33750069111
-
Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction
-
Innes AL, Woodruff PG, Ferrando RE, Donnelly S, Dolganov GM, Lazarus SC, Fahy JV. Epithelial mucin stores are increased in the large airways of smokers with airflow obstruction. Chest 2006;130: 1102-1108.
-
(2006)
Chest
, vol.130
, pp. 1102-1108
-
-
Innes, A.L.1
Woodruff, P.G.2
Ferrando, R.E.3
Donnelly, S.4
Dolganov, G.M.5
Lazarus, S.C.6
Fahy, J.V.7
-
41
-
-
17144457047
-
Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation
-
Saetta M, Turato G, Baraldo S, Zanin A, Braccioni F, Mapp CE, Maestrelli P, Cavallesco G, Papi A, Fabbri LM. Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation. Am J Respir Crit Care Med 2000;161:1016-1021.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 1016-1021
-
-
Saetta, M.1
Turato, G.2
Baraldo, S.3
Zanin, A.4
Braccioni, F.5
Mapp, C.E.6
Maestrelli, P.7
Cavallesco, G.8
Papi, A.9
Fabbri, L.M.10
-
42
-
-
65349110926
-
Small airway mucous metaplasia and inflammation in chronic obstructive pulmonary disease
-
Kim V, Kelemen SE, Abuel-Haija M, Gaughan J, Sharafkhaneh A, Evans CM, Dickey BF, Solomides CC, Rogers TJ, Criner GJ. Small airway mucous metaplasia and inflammation in chronic obstructive pulmonary disease. COPD 2008;5:329-338.
-
(2008)
COPD
, vol.5
, pp. 329-338
-
-
Kim, V.1
Kelemen, S.E.2
Abuel-Haija, M.3
Gaughan, J.4
Sharafkhaneh, A.5
Evans, C.M.6
Dickey, B.F.7
Solomides, C.C.8
Rogers, T.J.9
Criner, G.J.10
-
43
-
-
34447572685
-
Clinical relevance of airway remodelling in airway diseases
-
James AL, Wenzel S. Clinical relevance of airway remodelling in airway diseases. Eur Respir J 2007;30:134-155.
-
(2007)
Eur Respir J
, vol.30
, pp. 134-155
-
-
James, A.L.1
Wenzel, S.2
-
45
-
-
11144228939
-
Small airway morphometry and improvement in pulmonary function after lung volume reduction surgery
-
Kim V, Criner GJ, Abdallah HY, Gaughan JP, Furukawa S, Solomides CC. Small airway morphometry and improvement in pulmonary function after lung volume reduction surgery. Am J Respir Crit Care Med 2005;171:40-47.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 40-47
-
-
Kim, V.1
Criner, G.J.2
Abdallah, H.Y.3
Gaughan, J.P.4
Furukawa, S.5
Solomides, C.C.6
-
46
-
-
34548388998
-
The effect of small airway pathology on survival following lung volume reduction surgery (lvrs) [abstract]
-
Sciurba F,Martinez FJ, Rogers RM, Make B, Criner GJ, Cherniak RM, Patel SA, Chu F, Coxson HO, Sharafkhaneh A, et al. The effect of small airway pathology on survival following lung volume reduction surgery (LVRS) [abstract]. Proc Am Thorac Soc 2006;3:A712.
-
(2006)
Proc Am Thorac Soc
, vol.3
-
-
Sciurba, F.1
Martinez, F.J.2
Rogers, R.M.3
Make, B.4
Criner, G.J.5
Cherniak, R.M.6
Patel, S.A.7
Chu, F.8
Coxson, H.O.9
Sharafkhaneh, A.10
-
47
-
-
9644257234
-
Expression of erbb receptors and mucins in the airways of long term current smokers
-
O'Donnell RA, Richter A, Ward J, Angco G, Mehta A, Rousseau K, Swallow DM, Holgate ST, Djukanovic R, Davies DE, et al. Expression of ErbB receptors and mucins in the airways of long term current smokers. Thorax 2004;59:1032-1040.
-
(2004)
Thorax
, vol.59
, pp. 1032-1040
-
-
O'Donnell, R.A.1
Richter, A.2
Ward, J.3
Angco, G.4
Mehta, A.5
Rousseau, K.6
Swallow, D.M.7
Holgate, S.T.8
Djukanovic, R.9
Davies, D.E.10
-
48
-
-
85044706219
-
Pathology of chronic bronchitis
-
Reid LM. Pathology of chronic bronchitis. Lancet 1954;266:274-278.
-
(1954)
Lancet
, vol.266
, pp. 274-278
-
-
Reid, L.M.1
-
49
-
-
0022370533
-
Reassessment of inflammation of airways in chronic bronchitis
-
Mullen JB, Wright JL, Wiggs BR, Pare PD, Hogg JC. Reassessment of inflammation of airways in chronic bronchitis. Br Med J (Clin Res Ed) 1985;291:1235-1239.
-
(1985)
Br Med J (Clin Res Ed)
, vol.291
, pp. 1235-1239
-
-
Mullen, J.B.1
Wright, J.L.2
Wiggs, B.R.3
Pare, P.D.4
Hogg, J.C.5
-
50
-
-
34248531246
-
The association between small airway obstruction and emphysema phenotypes in copd
-
Kim WD, Ling SH, Coxson HO, English JC, Yee J, Levy RD, Pare PD, Hogg JC. The association between small airway obstruction and emphysema phenotypes in COPD. Chest 2007;131:1372-1378.
-
(2007)
Chest
, vol.131
, pp. 1372-1378
-
-
Kim, W.D.1
Ling, S.H.2
Coxson, H.O.3
English, J.C.4
Yee, J.5
Levy, R.D.6
Pare, P.D.7
Hogg, J.C.8
-
51
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103:779-788.
-
(1999)
J Clin Invest
, vol.103
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
Chen, Q.4
Geba, G.P.5
Wang, J.6
Zhang, Y.7
Elias, J.A.8
-
52
-
-
0033861859
-
T-cell subsets (th1 versus th2)
-
quiz 18 21
-
Romagnani S. T-cell subsets (Th1 versus Th2). Ann Allergy Asthma Immunol 2000;85:9-18; quiz 18, 21.
-
(2000)
Ann Allergy Asthma Immunol
, vol.85
, pp. 9-18
-
-
Romagnani, S.1
-
53
-
-
33750282677
-
The il-23/th(17) axis: Therapeutic targets for autoimmune inflammation
-
Kikly K, Liu L, Na S, Sedgwick JD. The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation. Curr Opin Immunol 2006;18: 670-675.
-
(2006)
Curr Opin Immunol
, Issue.18
, pp. 670-675
-
-
Kikly, K.1
Liu, L.2
Na, S.3
Sedgwick, J.D.4
-
54
-
-
0034833339
-
Il-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
-
Molet S, Hamid Q, Davoine F, Nutku E, Taha R, Page N, Olivenstein R, Elias J, Chakir J. IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 2001;108:430-438.
-
(2001)
J Allergy Clin Immunol
, vol.108
, pp. 430-438
-
-
Molet, S.1
Hamid, Q.2
Davoine, F.3
Nutku, E.4
Taha, R.5
Page, N.6
Olivenstein, R.7
Elias, J.8
Chakir, J.9
-
55
-
-
0037592950
-
Stimulation of airway mucin gene expression by interleukin (il)-17 through il-6 paracrine/autocrine loop
-
Chen Y, Thai P, Zhao YH, Ho YS, DeSouza MM, Wu R. Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop. J Biol Chem 2003;278:17036-17043.
-
(2003)
J Biol Chem
, vol.278
, pp. 17036-17043
-
-
Chen, Y.1
Thai, P.2
Zhao, Y.H.3
Ho, Y.S.4
DeSouza, M.M.5
Wu, R.6
-
56
-
-
0034018102
-
Relation of sputum inflammatory markers to symptoms and lung function changes in copd exacerbations
-
Bhowmik A, Seemungal TA, Sapsford RJ, Wedzicha JA. Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations. Thorax 2000;55:114-120.
-
(2000)
Thorax
, vol.55
, pp. 114-120
-
-
Bhowmik, A.1
Seemungal, T.A.2
Sapsford, R.J.3
Wedzicha, J.A.4
-
57
-
-
0026673538
-
Longitudinal lung function decline in subjects with respiratory symptoms
-
Sherman CB, Xu X, Speizer FE, Ferris BG Jr., Weiss ST, Dockery DW. Longitudinal lung function decline in subjects with respiratory symptoms. Am Rev Respir Dis 1992;146:855-859.
-
(1992)
Am Rev Respir Dis
, vol.146
, pp. 855-859
-
-
Sherman, C.B.1
Xu, X.2
Speizer, F.E.3
Ferris Jr., B.G.4
Weiss, S.T.5
Dockery, D.W.6
-
58
-
-
0025033561
-
Relation of ventilatory impairment and of chronic mucus hypersecretion to mortality from obstructive lung disease and from all causes
-
Lange P, Nyboe J, Appleyard M, Jensen G, Schnohr P. Relation of ventilatory impairment and of chronic mucus hypersecretion to mortality from obstructive lung disease and from all causes. Thorax 1990;45:579-585.
-
(1990)
Thorax
, vol.45
, pp. 579-585
-
-
Lange, P.1
Nyboe, J.2
Appleyard, M.3
Jensen, G.4
Schnohr, P.5
-
59
-
-
0037674024
-
Epidemiological studies in mucus hypersecretion
-
discussion 12- 9, 277-282
-
Vestbo J. Epidemiological studies in mucus hypersecretion. Novartis Found Symp 2002;248:3-12; discussion 12-9, 277-282.
-
(2002)
Novartis Found Symp
, vol.248
, pp. 3-12
-
-
Vestbo, J.1
-
60
-
-
67650653218
-
T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients
-
Di Stefano A, Caramori G, Gnemmi I, Contoli M, Vicari C, Capelli A, Magno F, D'Anna SE, Zanini A, Brun P, et al. T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients. Clin Exp Immunol 2009;157:316-324.
-
(2009)
Clin Exp Immunol
, vol.157
, pp. 316-324
-
-
Di Stefano, A.1
Caramori, G.2
Gnemmi, I.3
Contoli, M.4
Vicari, C.5
Capelli, A.6
Magno, F.7
D'Anna, S.E.8
Zanini, A.9
Brun, P.10
-
61
-
-
33645986683
-
Seven-year cumulative incidence of copd in an agestratified general population sample
-
Lindberg A, Eriksson B, Larsson LG, Ronmark E, Sandstrom T, Lundback B. Seven-year cumulative incidence of COPD in an agestratified general population sample. Chest 2006;129:879-885.
-
(2006)
Chest
, vol.129
, pp. 879-885
-
-
Lindberg, A.1
Eriksson, B.2
Larsson, L.G.3
Ronmark, E.4
Sandstrom, T.5
Lundback, B.6
-
62
-
-
67649777117
-
The natural history of chronic airflow obstruction revisited: An analysis of the framingham offspring cohort
-
Kohansal R, Martinez-Camblor P, Agusti A, Buist AS, Mannino DM, Soriano JB. The natural history of chronic airflow obstruction revisited: an analysis of the Framingham offspring cohort. Am J Respir Crit Care Med 2009;180:3-10.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 3-10
-
-
Kohansal, R.1
Martinez-Camblor, P.2
Agusti, A.3
Buist, A.S.4
Mannino, D.M.5
Soriano, J.B.6
-
63
-
-
0029150812
-
Chronic mucus hypersecretion in copd and death from pulmonary infection
-
Prescott E, Lange P, Vestbo J. Chronic mucus hypersecretion in COPD and death from pulmonary infection. Eur Respir J 1995;8:1333-1338.
-
(1995)
Eur Respir J
, vol.8
, pp. 1333-1338
-
-
Prescott, E.1
Lange, P.2
Vestbo, J.3
-
64
-
-
84873368494
-
Chronic bronchitis is associated with worse survival in advanced emphysema [abstract]
-
Kim V, Gaughan JP, Desai P, Washko GR, Make BJ, Han MK, Martinez FJ, Criner GJ. Chronic bronchitis is associated with worse survival in advanced emphysema [abstract]. Am J Respir Crit Care Med 2012;185:A1529.
-
(2012)
Am J Respir Crit Care Med
, vol.185
-
-
Kim, V.1
Gaughan, J.P.2
Desai, P.3
Washko, G.R.4
Make, B.J.5
Han, M.K.6
Martinez, F.J.7
Criner, G.J.8
-
65
-
-
0038752573
-
Lung function and mortality in the united states: Data from the first national health and nutrition examination survey follow up study
-
Mannino DM, Buist AS, Petty TL, Enright PL, Redd SC. Lung function and mortality in the United States: data from the First National Health and Nutrition Examination Survey follow up study. Thorax 2003;58:388-393.
-
(2003)
Thorax
, vol.58
, pp. 388-393
-
-
Mannino, D.M.1
Buist, A.S.2
Petty, T.L.3
Enright, P.L.4
Redd, S.C.5
-
66
-
-
0024432236
-
Respiratory risk factors and mortality: Longitudinal studies in washington county
-
Tockman MS, Comstock GW. Respiratory risk factors and mortality: longitudinal studies in Washington County, Maryland. Am Rev Respir Dis 1989;140:S56-S63.
-
(1989)
Maryland. Am Rev Respir Dis
, vol.140
-
-
Tockman, M.S.1
Comstock, G.W.2
-
67
-
-
0034105161
-
Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease
-
Seemungal TA, Donaldson GC, Bhowmik A, Jeffries DJ, Wedzicha JA. Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000;161:1608-1613.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 1608-1613
-
-
Seemungal, T.A.1
Donaldson, G.C.2
Bhowmik, A.3
Jeffries, D.J.4
Wedzicha, J.A.5
-
68
-
-
84870631733
-
Chronic bronchitis predicts greater frequency and severity of copd exacerbations in moderate to severe copd [abstract]
-
Kim V, Make BJ, Reagan EA, Han MK, Martinez FJ, Bowler R, Silverman EK, Crapo JD, Rogers TJ, Criner GJ, et al. Chronic bronchitis predicts greater frequency and severity of COPD exacerbations in moderate to severe COPD [abstract]. Am J Respir Crit Care Med 2012;185:A3735.
-
(2012)
Am J Respir Crit Care Med
, vol.185
-
-
Kim, V.1
Make, B.J.2
Reagan, E.A.3
Han, M.K.4
Martinez, F.J.5
Bowler, R.6
Silverman, E.K.7
Crapo, J.D.8
Rogers, T.J.9
Criner, G.J.10
-
69
-
-
79954555516
-
The effect of chronic sputum production on respiratory symptoms in severe copd
-
Kim V, Garfield JL, Grabianowski CL, Krahnke JS, Gaughan JP, Jacobs MR, Criner GJ. The effect of chronic sputum production on respiratory symptoms in severe COPD. COPD 2011;8:114-120.
-
(2011)
COPD
, vol.8
, pp. 114-120
-
-
Kim, V.1
Garfield, J.L.2
Grabianowski, C.L.3
Krahnke, J.S.4
Gaughan, J.P.5
Jacobs, M.R.6
Criner, G.J.7
-
70
-
-
0023636536
-
Structure of central airways in current smokers and ex-smokers with and without mucus hypersecretion: Relationship to lung function
-
Mullen JB, Wright JL, Wiggs BR, Pare PD, Hogg JC. Structure of central airways in current smokers and ex-smokers with and without mucus hypersecretion: relationship to lung function. Thorax 1987;42: 843-848.
-
(1987)
Thorax
, vol.42
, pp. 843-848
-
-
Mullen, J.B.1
Wright, J.L.2
Wiggs, B.R.3
Pare, P.D.4
Hogg, J.C.5
-
71
-
-
0026561094
-
Reversibility of airways injury over a 12-month period following smoking cessation
-
Swan GE, Hodgkin JE, Roby T, Mittman C, Jacobo N, Peters J. Reversibility of airways injury over a 12-month period following smoking cessation. Chest 1992;101:607-612.
-
(1992)
Chest
, vol.101
, pp. 607-612
-
-
Swan, G.E.1
Hodgkin, J.E.2
Roby, T.3
Mittman, C.4
Jacobo, N.5
Peters, J.6
-
72
-
-
38449107169
-
Conventional chest physical therapy for obstructive lung disease
-
discussion 1206- 1209
-
van der Schans CP. Conventional chest physical therapy for obstructive lung disease. Respir Care 2007;52:1198-1206, discussion 1206-1209.
-
(2007)
Respir Care
, vol.52
, pp. 1198-1206
-
-
Van Der Schans, C.P.1
-
73
-
-
34548593997
-
Mucolytics, expectorants, and mucokinetic medications
-
Rubin BK. Mucolytics, expectorants, and mucokinetic medications. Respir Care 2007;52:859-865.
-
(2007)
Respir Care
, vol.52
, pp. 859-865
-
-
Rubin, B.K.1
-
74
-
-
0015757462
-
A preliminary study of the effect of guaiphenesin on mucociliary clearance from the human lung
-
Thomson ML, Pavia D, McNicol MW. A preliminary study of the effect of guaiphenesin on mucociliary clearance from the human lung. Thorax 1973;28:742-747.
-
(1973)
Thorax
, vol.28
, pp. 742-747
-
-
Thomson, M.L.1
Pavia, D.2
McNicol, M.W.3
-
75
-
-
33748744717
-
Hypertonic saline therapy in cystic fibrosis: Evidence against the proposed mechanism involving aquaporins
-
Levin MH, Sullivan S, Nielson D, Yang B, Finkbeiner WE, Verkman AS. Hypertonic saline therapy in cystic fibrosis: evidence against the proposed mechanism involving aquaporins. J Biol Chem 2006;281: 25803-25812.
-
(2006)
J Biol Chem
, vol.281
, pp. 25803-25812
-
-
Levin, M.H.1
Sullivan, S.2
Nielson, D.3
Yang, B.4
Finkbeiner, W.E.5
Verkman, A.S.6
-
76
-
-
34249662628
-
Cystic fibrosis: A disease of vulnerability to airway surface dehydration
-
Boucher RC. Cystic fibrosis: a disease of vulnerability to airway surface dehydration. Trends Mol Med 2007;13:231-240.
-
(2007)
Trends Mol Med
, vol.13
, pp. 231-240
-
-
Boucher, R.C.1
-
77
-
-
65449157256
-
Effectiveness and safety of hypertonic saline inhalation combined with exercise training in patients with chronic obstructive pulmonary disease: A randomized trial
-
Valderramas SR, Atallah AN. Effectiveness and safety of hypertonic saline inhalation combined with exercise training in patients with chronic obstructive pulmonary disease: a randomized trial. Respir Care 2009;54:327-333.
-
(2009)
Respir Care
, vol.54
, pp. 327-333
-
-
Valderramas, S.R.1
Atallah, A.N.2
-
78
-
-
0027191332
-
Markers of mucus secretion and dna levels in induced sputum from asthmatic and from healthy subjects
-
Fahy JV, Steiger DJ, Liu J, Basbaum CB, Finkbeiner WE, Boushey HA. Markers of mucus secretion and DNA levels in induced sputum from asthmatic and from healthy subjects. Am Rev Respir Dis 1993; 147:1132-1137.
-
(1993)
Am Rev Respir Dis
, vol.147
, pp. 1132-1137
-
-
Fahy, J.V.1
Steiger, D.J.2
Liu, J.3
Basbaum, C.B.4
Finkbeiner, W.E.5
Boushey, H.A.6
-
79
-
-
0031901989
-
Treatment of idiopathic bronchiectasis with aerosolized recombinant human dnase i. Rhdnase study group
-
O'Donnell AE, Barker AF, Ilowite JS, Fick RB. Treatment of idiopathic bronchiectasis with aerosolized recombinant human DNase I. rhDNase Study Group. Chest 1998;113:1329-1334.
-
(1998)
Chest
, vol.113
, pp. 1329-1334
-
-
O'Donnell, A.E.1
Barker, A.F.2
Ilowite, J.S.3
Fick, R.B.4
-
80
-
-
0024563433
-
Effect of camp on ciliary function in rabbit tracheal epithelial cells
-
Tamaoki J, Kondo M, Takizawa T. Effect of cAMP on ciliary function in rabbit tracheal epithelial cells. J Appl Physiol 1989;66:1035-1039.
-
(1989)
J Appl Physiol
, vol.66
, pp. 1035-1039
-
-
Tamaoki, J.1
Kondo, M.2
Takizawa, T.3
-
81
-
-
0027080197
-
The effects of salmeterol and salbutamol on ciliary beat frequency of cultured human bronchial epithelial cells, in vitro
-
Devalia JL, Sapsford RJ, Rusznak C, Toumbis MJ, Davies RJ. The effects of salmeterol and salbutamol on ciliary beat frequency of cultured human bronchial epithelial cells, in vitro. Pulm Pharmacol 1992;5:257-263.
-
(1992)
Pulm Pharmacol
, vol.5
, pp. 257-263
-
-
Devalia, J.L.1
Sapsford, R.J.2
Rusznak, C.3
Toumbis, M.J.4
Davies, R.J.5
-
82
-
-
0036912150
-
Effects of beta-agonists on airway epithelial cells
-
Salathe M. Effects of beta-agonists on airway epithelial cells. J Allergy Clin Immunol 2002;110:S275-S281.
-
(2002)
J Allergy Clin Immunol
, vol.110
-
-
Salathe, M.1
-
83
-
-
40649086036
-
Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model
-
Nguyen LP, Omoluabi O, Parra S, Frieske JM, Clement C, Ammar-Aouchiche Z, Ho SB, Ehre C, Kesimer M, Knoll BJ, et al. Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model. Am J Respir Cell Mol Biol 2008;38: 256-262.
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 256-262
-
-
Nguyen, L.P.1
Omoluabi, O.2
Parra, S.3
Frieske, J.M.4
Clement, C.5
Ammar-Aouchiche, Z.6
Ho, S.B.7
Ehre, C.8
Kesimer, M.9
Knoll, B.J.10
-
84
-
-
60549103882
-
Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model
-
Nguyen LP, Lin R, Parra S, Omoluabi O, Hanania NA, Tuvim MJ, Knoll BJ, Dickey BF, Bond RA. Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model. Proc Natl Acad Sci USA 2009;106:2435-2440.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2435-2440
-
-
Nguyen, L.P.1
Lin, R.2
Parra, S.3
Omoluabi, O.4
Hanania, N.A.5
Tuvim, M.J.6
Knoll, B.J.7
Dickey, B.F.8
Bond, R.A.9
-
85
-
-
0022347060
-
Effects of methylxanthines on airway mucociliary function
-
Wanner A. Effects of methylxanthines on airway mucociliary function. Am J Med 1985;79:16-21.
-
(1985)
Am J Med
, vol.79
, pp. 16-21
-
-
Wanner, A.1
-
87
-
-
0021803108
-
The efficacy of orally administered theophylline, inhaled salbutamol, and a combination of the two as chronic therapy in the management of chronic bronchitis with reversible air-flow obstruction
-
Taylor DR, Buick B, Kinney C, Lowry RC, McDevitt DG. The efficacy of orally administered theophylline, inhaled salbutamol, and a combination of the two as chronic therapy in the management of chronic bronchitis with reversible air-flow obstruction. Am Rev Respir Dis 1985;131:747-751.
-
(1985)
Am Rev Respir Dis
, vol.131
, pp. 747-751
-
-
Taylor, D.R.1
Buick, B.2
Kinney, C.3
Lowry, R.C.4
McDevitt, D.G.5
-
88
-
-
0020402676
-
Lung mucociliary function in man: Interdependence of bronchial and tracheal mucus transport velocities with lung clearance in bronchial asthma and healthy subjects
-
Foster WM, Langenback EG, Bergofsky EH. Lung mucociliary function in man: interdependence of bronchial and tracheal mucus transport velocities with lung clearance in bronchial asthma and healthy subjects. Ann Occup Hyg 1982;26:227-244.
-
(1982)
Ann Occup Hyg
, vol.26
, pp. 227-244
-
-
Foster, W.M.1
Langenback, E.G.2
Bergofsky, E.H.3
-
89
-
-
0030903442
-
Quality of life changes in copd patients treated with salmeterol
-
Jones PW, Bosh TK. Quality of life changes in COPD patients treated with salmeterol. Am J Respir Crit Care Med 1997;155:1283-1289.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 1283-1289
-
-
Jones, P.W.1
Bosh, T.K.2
-
90
-
-
0032909636
-
Efficacy of salmeterol xinafoate in the treatment of copd
-
Mahler DA, Donohue JF, Barbee RA, Goldman MD, Gross NJ, Wisniewski ME, Yancey SW, Zakes BA, Rickard KA, Anderson WH. Efficacy of salmeterol xinafoate in the treatment of COPD. Chest 1999;115:957-965.
-
(1999)
Chest
, vol.115
, pp. 957-965
-
-
Mahler, D.A.1
Donohue, J.F.2
Barbee, R.A.3
Goldman, M.D.4
Gross, N.J.5
Wisniewski, M.E.6
Yancey, S.W.7
Zakes, B.A.8
Rickard, K.A.9
Anderson, W.H.10
-
91
-
-
33645116728
-
Effects of tiotropium with and without formoterol on airflow obstruction and resting hyperinflation in patients with copd
-
van Noord JA, Aumann JL, Janssens E, Verhaert J, Smeets JJ, Mueller A, Cornelissen PJ. Effects of tiotropium with and without formoterol on airflow obstruction and resting hyperinflation in patients with COPD. Chest 2006;129:509-517.
-
(2006)
Chest
, vol.129
, pp. 509-517
-
-
Van Noord, J.A.1
Aumann, J.L.2
Janssens, E.3
Verhaert, J.4
Smeets, J.J.5
Mueller, A.6
Cornelissen, P.J.7
-
92
-
-
0026497752
-
The influence of a new beta agonist: Formoterol on mucociliary function
-
Melloni B, Germouty J. The influence of a new beta agonist: formoterol on mucociliary function. Rev Mal Respir 1992;9:503-507.
-
(1992)
Rev Mal Respir
, vol.9
, pp. 503-507
-
-
Melloni, B.1
Germouty, J.2
-
93
-
-
4544353992
-
Submucosal glands and airway defense
-
Wine JJ, Joo NS. Submucosal glands and airway defense. Proc Am Thorac Soc 2004;1:47-53.
-
(2004)
Proc Am Thorac Soc
, vol.1
, pp. 47-53
-
-
Wine, J.J.1
Joo, N.S.2
-
94
-
-
48749124897
-
The epithelial cholinergic system of the airways
-
Kummer W, Lips KS, Pfeil U. The epithelial cholinergic system of the airways. Histochem Cell Biol 2008;130:219-234.
-
(2008)
Histochem Cell Biol
, vol.130
, pp. 219-234
-
-
Kummer, W.1
Lips, K.S.2
Pfeil, U.3
-
95
-
-
71249094666
-
Alternative mechanisms for tiotropium
-
Bateman ED, Rennard S, Barnes PJ, Dicpinigaitis PV, Gosens R, Gross NJ, Nadel JA, Pfeifer M, Racke K, Rabe KF, et al. Alternative mechanisms for tiotropium. Pulm Pharmacol Ther 2009;22:533-542.
-
(2009)
Pulm Pharmacol Ther
, vol.22
, pp. 533-542
-
-
Bateman, E.D.1
Rennard, S.2
Barnes, P.J.3
Dicpinigaitis, P.V.4
Gosens, R.5
Gross, N.J.6
Nadel, J.A.7
Pfeifer, M.8
Racke, K.9
Rabe, K.F.10
-
96
-
-
0021139702
-
Sputum changes associated with the use of ipratropium bromide
-
Ghafouri MA, Patil KD, Kass I. Sputum changes associated with the use of ipratropium bromide. Chest 1984;86:387-393.
-
(1984)
Chest
, vol.86
, pp. 387-393
-
-
Ghafouri, M.A.1
Patil, K.D.2
Kass, I.3
-
97
-
-
0027450966
-
The acute effect of ipratropium bromide bronchodilator therapy on cough clearance in copd
-
Bennett WD, Chapman WF, Mascarella JM. The acute effect of ipratropium bromide bronchodilator therapy on cough clearance in COPD. Chest 1993;103:488-495.
-
(1993)
Chest
, vol.103
, pp. 488-495
-
-
Bennett, W.D.1
Chapman, W.F.2
Mascarella, J.M.3
-
98
-
-
0033748430
-
The spirometric efficacy of once-daily dosing with tiotropium in stable copd: A 13-week multicenter trial
-
Casaburi R, Briggs DD Jr., Donohue JF, Serby CW, Menjoge SS, Witek TJ Jr. The spirometric efficacy of once-daily dosing with tiotropium in stable COPD: a 13-week multicenter trial. The US Tiotropium Study Group. Chest 2000;118:1294-1302.
-
(2000)
The US Tiotropium Study Group. Chest
, vol.118
, pp. 1294-1302
-
-
Casaburi, R.1
Briggs Jr., D.D.2
Donohue, J.F.3
Serby, C.W.4
Menjoge, S.S.5
Witek Jr., T.J.6
-
99
-
-
2442516033
-
The effect of inhaled tiotropium bromide on lung mucociliary clearance in patients with copd
-
Hasani A, Toms N, Agnew JE, Sarno M, Harrison AJ, Dilworth P. The effect of inhaled tiotropium bromide on lung mucociliary clearance in patients with COPD. Chest 2004;125:1726-1734.
-
(2004)
Chest
, vol.125
, pp. 1726-1734
-
-
Hasani, A.1
Toms, N.2
Agnew, J.E.3
Sarno, M.4
Harrison, A.J.5
Dilworth, P.6
-
100
-
-
0037097883
-
The effects of inhaled fluticasone on airway inflammation in chronic obstructive pulmonary disease: A double-blind, placebo-controlled biopsy study
-
Hattotuwa KL, Gizycki MJ, Ansari TW, Jeffery PK, Barnes NC. The effects of inhaled fluticasone on airway inflammation in chronic obstructive pulmonary disease: a double-blind, placebo-controlled biopsy study. Am J Respir Crit Care Med 2002;165:1592-1596.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 1592-1596
-
-
Hattotuwa, K.L.1
Gizycki, M.J.2
Ansari, T.W.3
Jeffery, P.K.4
Barnes, N.C.5
-
101
-
-
67749130687
-
Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma
-
Innes AL, Carrington SD, Thornton DJ, Kirkham S, Rousseau K, Dougherty RH, Raymond WW, Caughey GH, Muller SJ, Fahy JV. Ex vivo sputum analysis reveals impairment of protease-dependent mucus degradation by plasma proteins in acute asthma. Am J Respir Crit Care Med 2009;180:203-210.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 203-210
-
-
Innes, A.L.1
Carrington, S.D.2
Thornton, D.J.3
Kirkham, S.4
Rousseau, K.5
Dougherty, R.H.6
Raymond, W.W.7
Caughey, G.H.8
Muller, S.J.9
Fahy, J.V.10
-
102
-
-
18144429417
-
Effects of ciclesonide and fluticasone propionate on allergen-induced airway inflammation and remodeling features
-
Leung SY, Eynott P, Nath P, Chung KF. Effects of ciclesonide and fluticasone propionate on allergen-induced airway inflammation and remodeling features. J Allergy Clin Immunol 2005;115:989-996.
-
(2005)
J Allergy Clin Immunol
, vol.115
, pp. 989-996
-
-
Leung, S.Y.1
Eynott, P.2
Nath, P.3
Chung, K.F.4
-
103
-
-
33644611695
-
Dexamethasone-mediated repression of muc5ac gene expression in human lung epithelial cells
-
Chen Y, Nickola TJ, DiFronzo NL, Colberg-Poley AM, Rose MC. Dexamethasone-mediated repression of MUC5AC gene expression in human lung epithelial cells. Am J Respir Cell Mol Biol 2006;34: 338-347.
-
(2006)
Am J Respir Cell Mol Biol
, vol.34
, pp. 338-347
-
-
Chen, Y.1
Nickola, T.J.2
DiFronzo, N.L.3
Colberg-Poley, A.M.4
Rose, M.C.5
-
104
-
-
0031690355
-
Budesonide affects allergic mucociliary dysfunction
-
O'Riordan TG, Mao Y, Otero R, Lopez J, Sabater JR, Abraham WM. Budesonide affects allergic mucociliary dysfunction. J Appl Physiol 1998;85:1086-1091.
-
(1998)
J Appl Physiol
, vol.85
, pp. 1086-1091
-
-
O'Riordan, T.G.1
Mao, Y.2
Otero, R.3
Lopez, J.4
Sabater, J.R.5
Abraham, W.M.6
-
105
-
-
0034643610
-
Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: The isolde trial
-
Burge PS, Calverley PM, Jones PW, Spencer S, Anderson JA, Maslen TK. Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial. BMJ 2000;320:1297-1303.
-
(2000)
BMJ
, vol.320
, pp. 1297-1303
-
-
Burge, P.S.1
Calverley, P.M.2
Jones, P.W.3
Spencer, S.4
Anderson, J.A.5
Maslen, T.K.6
-
106
-
-
0037425745
-
Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: A randomised controlled trial
-
TRial of Inhaled STeroids ANd long-acting beta2 agonists study group
-
Calverley P, Pauwels R, Vestbo J, Jones P, Pride N, Gulsvik A, Anderson J, Maden C. TRial of Inhaled STeroids ANd long-acting beta2 agonists study group. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2003;361:449-456.
-
(2003)
Lancet
, vol.361
, pp. 449-456
-
-
Calverley, P.1
Pauwels, R.2
Vestbo, J.3
Jones, P.4
Pride, N.5
Gulsvik, A.6
Anderson, J.7
Maden, C.8
-
107
-
-
0037246566
-
Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease
-
Szafranski W, Cukier A, Ramirez A, Menga G, Sansores R, Nahabedian S, Peterson S, Olsson H. Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease. Eur Respir J 2003;21:74-81.
-
(2003)
Eur Respir J
, vol.21
, pp. 74-81
-
-
Szafranski, W.1
Cukier, A.2
Ramirez, A.3
Menga, G.4
Sansores, R.5
Nahabedian, S.6
Peterson, S.7
Olsson, H.8
-
109
-
-
69149103642
-
Roflumilast in symptomatic chronic obstructive pulmonary disease: Two randomised clinical trials
-
M2-124 and M2-125 study groups
-
Calverley PM, Rabe KF, Goehring UM, Kristiansen S, Fabbri LM, Martinez FJ. M2-124 and M2-125 study groups. Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials. Lancet 2009;374:685-694.
-
(2009)
Lancet
, vol.374
, pp. 685-694
-
-
Calverley, P.M.1
Rabe, K.F.2
Goehring, U.M.3
Kristiansen, S.4
Fabbri, L.M.5
Martinez, F.J.6
-
110
-
-
69149098943
-
Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: Two randomised clinical trials M2-127 and m2-128 study groups
-
Fabbri LM, Calverley PM, Izquierdo-Alonso JL, Bundschuh DS, Brose M, Martinez FJ, Rabe KF. M2-127 and M2-128 study groups. Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet 2009;374:695-703.
-
(2009)
Lancet
, vol.374
, pp. 695-703
-
-
Fabbri, L.M.1
Calverley, P.M.2
Izquierdo-Alonso, J.L.3
Bundschuh, D.S.4
Brose, M.5
Martinez, F.J.6
Rabe, K.F.7
-
111
-
-
0034034334
-
Oxidants/antioxidants and copd
-
MacNee W. Oxidants/antioxidants and COPD. Chest 2000;117:303S-317.S.
-
(2000)
Chest
, vol.117
-
-
MacNee, W.1
-
112
-
-
77954083932
-
Carbocisteine normalizes the viscous property of mucus through regulation of fucosylated and sialylated sugar chain on airway mucins
-
Ishibashi Y, Takayama G, Inouye Y, Taniguchi A. Carbocisteine normalizes the viscous property of mucus through regulation of fucosylated and sialylated sugar chain on airway mucins. Eur J Pharmacol 2010;641:226-228.
-
(2010)
Eur J Pharmacol
, vol.641
, pp. 226-228
-
-
Ishibashi, Y.1
Takayama, G.2
Inouye, Y.3
Taniguchi, A.4
-
113
-
-
20944433417
-
Effects of n-acetylcysteine on outcomes in chronic obstructive pulmonary disease (bronchitis randomized on nac cost-utility study, broncus): A randomised placebo-controlled trial
-
Decramer M, Rutten-van Molken M, Dekhuijzen PN, Troosters T, van Herwaarden C, Pellegrino R, van Schayck CP, Olivieri D, Del Donno M, De Backer W, et al. Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial. Lancet 2005;365:1552-1560.
-
(2005)
Lancet
, vol.365
, pp. 1552-1560
-
-
Decramer, M.1
Rutten-Van Molken, M.2
Dekhuijzen, P.N.3
Troosters, T.4
Van Herwaarden, C.5
Pellegrino, R.6
Van Schayck, C.P.7
Olivieri, D.8
Del Donno, M.9
De Backer, W.10
-
114
-
-
44849100529
-
Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (peace study): A randomised placebo-controlled study
-
Zheng JP, Kang J, Huang SG, Chen P, Yao WZ, Yang L, Bai CX, Wang CZ, Wang C, Chen BY, et al. Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study. Lancet 2008;371: 2013-2018.
-
(2008)
Lancet
, vol.371
, pp. 2013-2018
-
-
Zheng, J.P.1
Kang, J.2
Huang, S.G.3
Chen, P.4
Yao, W.Z.5
Yang, L.6
Bai, C.X.7
Wang, C.Z.8
Wang, C.9
Chen, B.Y.10
-
115
-
-
77950937105
-
Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease
-
Poole P, Black PN. Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2010; (2):CD001287.
-
(2010)
Cochrane Database Syst Rev
, vol.2
-
-
Poole, P.1
Black, P.N.2
-
116
-
-
1042299785
-
Macrolides for the treatment of chronic sinusitis asthma and copd
-
quiz 60S-61.S
-
Gotfried MH. Macrolides for the treatment of chronic sinusitis, asthma, and COPD. Chest 2004;125:52S-60S; quiz 60S-61.S.
-
(2004)
Chest
, vol.125
-
-
Gotfried, M.H.1
-
117
-
-
56749157688
-
Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations
-
Seemungal TA, Wilkinson TM, Hurst JR, Perera WR, Sapsford RJ, Wedzicha JA. Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations. Am J Respir Crit Care Med 2008;178:1139-1147.
-
Am J Respir Crit Care Med
, vol.2008
, Issue.178
, pp. 1139-1147
-
-
Seemungal, T.A.1
Wilkinson, T.M.2
Hurst, J.R.3
Perera, W.R.4
Sapsford, R.J.5
Wedzicha, J.A.6
-
118
-
-
80052157895
-
Copd clinical research network. Azithromycin for prevention of exacerbations of copd
-
Albert RK, Connett J, Bailey WC, Casaburi R, Cooper JA Jr., Criner GJ, Curtis JL, Dransfield MT, Han MK, Lazarus SC, et al., COPD Clinical Research Network. Azithromycin for prevention of exacerbations of COPD. N Engl J Med 2011;365:689-698.
-
(2011)
N Engl J Med
, vol.365
, pp. 689-698
-
-
Albert, R.K.1
Connett, J.2
Bailey, W.C.3
Casaburi, R.4
Cooper Jr., J.A.5
Criner, G.J.6
Curtis, J.L.7
Dransfield, M.T.8
Han, M.K.9
Lazarus, S.C.10
-
119
-
-
79959272070
-
Cough and sputum production as risk factors for poor outcomes in patients with copd
-
Miravitlles M. Cough and sputum production as risk factors for poor outcomes in patients with COPD. Respir Med 2011;105:1118-1128.
-
(2011)
Respir Med
, vol.105
, pp. 1118-1128
-
-
Miravitlles, M.1
-
120
-
-
43349158916
-
New concepts in the pathobiology of chronic obstructive pulmonary disease
-
Kim V, Rogers TJ, Criner GJ. New concepts in the pathobiology of chronic obstructive pulmonary disease. Proc Am Thor Soc 2008;5: 478-485.
-
(2008)
Proc Am Thor Soc
, vol.5
, pp. 478-485
-
-
Kim, V.1
Rogers, T.J.2
Criner, G.J.3
-
121
-
-
0022453116
-
Is respiratory mucus hypersecretion really an innocent disorder? A 22-year mortality survey of 1,061 working men
-
Annesi I, Kauffmann F. Is respiratory mucus hypersecretion really an innocent disorder? A 22-year mortality survey of 1,061 working men. Am Rev Respir Dis 1986;134:688-693.
-
(1986)
Am Rev Respir Dis
, vol.134
, pp. 688-693
-
-
Annesi, I.1
Kauffmann, F.2
-
122
-
-
84863471264
-
Chronic cough and sputum production: A clinical copd phenotype?
-
Burgel PR. Chronic cough and sputum production: a clinical COPD phenotype? Eur Respir J 2012;40:4-6.
-
(2012)
Eur Respir J
, vol.40
, pp. 4-6
-
-
Burgel, P.R.1
|