Hypertonic saline therapy in cystic fibrosis: Evidence against the proposed mechanism involving aquaporins

Journal of Biological Chemistry

Volumn 281, Issue 35, 2006, Pages 25803-25812

  Levin, Marc H ^a,b   Sullivan, Shannon ^a   Nielson, Dennis ^a   Yang, Baoxue ^a   Finkbeiner, Walter E ^b   Verkman, A S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL MEMBRANES; CELLS; LIVING SYSTEMS STUDIES; MOLECULAR BIOLOGY; PH;

AQUAPORINS; CYSTIC FIBROSIS; OF HYPERTONIC SALINE;

PULMONARY DISEASES;

AMILORIDE; AQUAPORIN; SODIUM CHLORIDE;

ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG EFFECT; DRUG MECHANISM; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; METHODOLOGY; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; RAT; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TEMPERATURE DEPENDENCE; THYROID CELL; WATER PERMEABILITY;

AMILORIDE; ANIMALS; AQUAPORINS; CELL MEMBRANE; CYSTIC FIBROSIS; EPITHELIAL CELLS; HUMANS; MODELS, BIOLOGICAL; PERFUSION; PERMEABILITY; RATS; RATS, INBRED F344; SALINE SOLUTION, HYPERTONIC; THYROID GLAND; WATER;

EID: 33748744717     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604332200     Document Type: Article

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