Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonucleasethat translocates to the nucleus during apoptosis

Journal of Biological Chemistry

Volumn 288, Issue 5, 2013, Pages 3460-3468

  Errami, Youssef ^a   Naura, Amarjit S ^a   Kim, Hogyoung ^a   Ju, Jihang ^a   Suzuki, Yasuhiro ^a   El Bahrawy, Ali H ^a,b   Ghonim, Mohamed A ^a,c   Hemeida, Ramadan A ^b   Mansy, Moselhy S ^c   Zhang, Jianhua ^d   Xu, Ming ^e   Smulson, Mark E ^a,f   Brim, Hassan ^g   Boulares, A Hamid ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b AL AZHAR UNIVERSITY   (Egypt)

^c Al Azhar University   (Egypt)

^d University of Alabama at Birmingham   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

^f GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g HOWARD UNIVERSITY CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADP-RIBOSE; APOPTOSIS INDUCTION; APOPTOTIC; CASPASE-3 ACTIVATION; CASPASE-ACTIVATED DNASE; CO-EXPRESSION; COOPERATIVE ACTIVITY; CYTOSOLS; DEOXYRIBONUCLEASE; DNA FRAGMENTATION; ENDONUCLEASES; ENDOPLASMIC RETICULUM; EXPRESSION LEVELS; NUCLEAR ACCUMULATION; SERINE PROTEASE; TUMOR NECROSIS FACTORS;

AMINO ACIDS; CALCIUM; CELL MEMBRANES; CHELATION; CHROMOSOMES; DNA;

CELL DEATH;

CALCIUM ION; CASPASE 3; CASPASE ACTIVATED DEOXYRIBONUCLEASE; CYSTEINE PROTEINASE; ENDONUCLEASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN DNAS1L3; SERINE PROTEINASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL NUCLEUS; CHROMATIN; CONTROLLED STUDY; DNA FRAGMENTATION; EMBRYO; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME REGULATION; FEMALE; HUMAN; HUMAN CELL; INTERNUCLEOSOMAL DNA FRAGMENTATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BASE PAIRING; CALCIUM; CELL LINE, TUMOR; CELL NUCLEUS; CYSTEINE PROTEASES; DEOXYRIBONUCLEASES; DNA FRAGMENTATION; ENDODEOXYRIBONUCLEASES; ENDOPLASMIC RETICULUM; ETOPOSIDE; HERPES SIMPLEX VIRUS PROTEIN VMW65; HUMANS; MICE; NUCLEOSOMES; POLY(ADP-RIBOSE) POLYMERASES; PROTEASE INHIBITORS; PROTEIN TRANSPORT; SERINE PROTEASES;

EID: 84873324177     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.423061     Document Type: Article

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