Inhibition of platelet-derived growth factor receptor tyrosine kinase and downstream signaling pathways by Compound C

Cellular Signalling

Volumn 25, Issue 4, 2013, Pages 883-897

  Kwon, Hyun Jin ^a   Kim, Go Eun ^a   Lee, Yun Taek ^a   Jeong, Meong Sook ^a   Kang, Insug ^b   Yang, Dongki ^a   Yeo, Eui Ju ^a  

^a Gachon University   (South Korea)

^b Kyung Hee University   (South Korea)

Author keywords

Akt; AMP activated protein kinase; Compound C; Human diploid fibroblasts; Platelet derived growth factor receptor; Receptor tyrosine kinase

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN E; CYCLINE; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN P85; PROTEIN TYROSINE KINASE; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CELL LINE; CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE; G1 PHASE CELL CYCLE CHECKPOINTS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; PYRAZOLES; PYRIMIDINES; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, IGF TYPE 1; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84873316174     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.12.016     Document Type: Article

References (61)

1. Carling D. Trends in Biochemical Sciences 2004, 29:18-24.
2. Hurley R.L., Barre L.K., Wood S.D., Anderson K.A., Kemp B.E., Means A.R., Witters L.A. Journal of Biological Chemistry 2006, 281:36662-36672.
3. Steinberg G.R., Kemp B.E. Physiological Reviews 2009, 89:1025-1078.
4. Li W., Fan J., Chen M., Guan S., Sawcer D., Bokoch G.M., Woodley D.T. Molecular Biology of the Cell 2004, 15:294-309.
5. Li X., Han Y., Pang W., Li C., Xie X., Shyy J.Y., Zhu Y. Arteriosclerosis, Thrombosis, and Vascular Biology 2008, 28:1789-1795.
6. Kim H.S., Hwang J.T., Yun H., Chi S.G., Lee S.J., Kang I., Yoon K.S., Choe W.J., Kim S.S., Ha J. Journal of Biological Chemistry 2008, 283:3731-3742.
7. Lieberthal W., Zhang L., Patel V.A., Levine J.S. American Journal of Physiology. Renal Physiology 2011, 301:F1177-F1192.
8. Zhang B.B., Zhou G., Li C. Cell Metabolism 2009, 9:407-416.
9. Downward J. Current Opinion in Cell Biology 1998, 10:262-267.
10. Sarbassov D.D., Guertin D.A., Ali S.M., Sabatini D.M. Science 2005, 307:1098-1101.
11. Liang J., Slingerland J.M. Cell Cycle 2003, 2:339-345.
12. Choudhury G.G., Mahimainathan L., Das F., Venkatesan B., Ghosh-Choudhury N. Cellular Signalling 2006, 18:1854-1864.
13. Brunet A., Bonni A., Zigmond M.J., Lin M.Z., Juo P., Hu L.S., Anderson M.J., Arden K.C., Blenis J., Greenberg M.E. Cell 1999, 96:857-868.
14. Matsui T., Rosenzweig A. Journal of Molecular and Cellular Cardiology 2005, 38:63-71.
15. Chen E.Y., Mazure N.M., Cooper J.A., Giaccia A.J. Cancer Research 2001, 61:2429-2433.
16. Hers I., Vincent E.E., Tavare J.M. Cellular Signalling 2011, 23:1515-1527.
17. Kovacic S., Soltys C.L., Barr A.J., Shiojima I., Walsh K., Dyck J.R. Journal of Biological Chemistry 2003, 278:39422-39427.
18. Hahn-Windgassen A., Nogueira V., Chen C.C., Skeen J.E., Sonenberg N., Hay N. Journal of Biological Chemistry 2005, 280:32081-32089.
19. Horman S., Vertommen D., Heath R., Neumann D., Mouton V., Woods A., Schlattner U., Wallimann T., Carling D., Hue L., Rider M.H. Journal of Biological Chemistry 2006, 281:5335-5340.
20. King T.D., Song L., Jope R.S. Biochemical Pharmacology 2006, 71:1637-1647.
21. Priebe A., Tan L., Wahl H., Kueck A., He G., Kwok R., Opipari A., Liu J.R. Gynecologic Oncology 2011, 122:389-395.
22. Hardie D.G., Scott J.W., Pan D.A., Hudson E.R. FEBS Letters 2003, 546:113-120.
23. Boyce S.T., Ham R.G. The Journal of Investigative Dermatology 1983, 81:33s-40s.
24. Laderoute K.R., Amin K., Calaoagan J.M., Knapp M., Le T., Orduna J., Foretz M., Viollet B. Molecular and Cellular Biology 2006, 26:5336-5347.
25. Choi A.Y., Choi J.H., Yoon H., Hwang K.Y., Noh M.H., Choe W., Yoon K.S., Ha J., Yeo E.J., Kang I. European Journal of Pharmacology 2011, 668:115-126.
26. Kwon H.J., Rhim J.H., Jang I.S., Kim G.E., Park S.C., Yeo E.J. Experimental & Molecular Medicine 2010, 42:254-269.
27. Abdiche Y.N., Lindquist K.C., Pinkerton A., Pons J., Rajpal A. Analytical Biochemistry 2011, 411:139-151.
28. Sayan B.S., Sayan A.E., Knight R.A., Melino G., Cohen G.M. Journal of Biological Chemistry 2006, 281:13566-13573.
29. Leclerc G.M., Leclerc G.J., Fu G., Barredo J.C. Journal of Molecular Signaling 2010, 5:15.
30. Ouchi N., Kobayashi H., Kihara S., Kumada M., Sato K., Inoue T., Funahashi T., Walsh K. Journal of Biological Chemistry 2004, 279:1304-1309.
31. Fredriksson L., Li H., Eriksson U. Cytokine & Growth Factor Reviews 2004, 15:197-204.
32. Wu E., Palmer N., Tian Z., Moseman A.P., Galdzicki M., Wang X., Berger B., Zhang H., Kohane I.S. PLoS One 2008, 3:e3794.
33. Tallquist M., Kazlauskas A. Cytokine & Growth Factor Reviews 2004, 15:205-213.
34. Viana R., Towler M.C., Pan D.A., Carling D., Viollet B., Hardie D.G., Sanz P. Journal of Biological Chemistry 2007, 282:16117-16125.
35. Forde J.E., Dale T.C. Cellular and Molecular Life Sciences 2007, 64:1930-1944.
36. Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., Wu M., Ventre J., Doebber T., Fujii N., Musi N., Hirshman M.F., Goodyear L.J., Moller D.E. The Journal of Clinical Investigation 2001, 108:1167-1174.
37. Towler M.C., Hardie D.G. Circulation Research 2007, 100:328-341.
38. Jones R.G., Plas D.R., Kubek S., Buzzai M., Mu J., Xu Y., Birnbaum M.J., Thompson C.B. Molecular Cell 2005, 18:283-293.
39. Vucicevic L., Misirkic M., Janjetovic K., Harhaji-Trajkovic L., Prica M., Stevanovic D., Isenovic E., Sudar E., Sumarac-Dumanovic M., Micic D., Trajkovic V. Biochemical Pharmacology 2009, 77:1684-1693.
40. Hiyama H., Iavarone A., Reeves S.A. Oncogene 1998, 16:1513-1523.
41. Moses S.A., Ali M.A., Zuohe S., Du-Cuny L., Zhou L.L., Lemos R., Ihle N., Skillman A.G., Zhang S., Mash E.A., Powis G., Meuillet E.J. Cancer Research 2009, 69:5073-5081.
42. Kovalenko M., Gazit A., Bohmer A., Rorsman C., Ronnstrand L., Heldin C.H., Waltenberger J., Bohmer F.D., Levitzki A. Cancer Research 1994, 54:6106-6114.
43. Pietras K., Sjoblom T., Rubin K., Heldin C.H., Ostman A. Cancer Cell 2003, 3:439-443.
44. Raines E.W. Cytokine & Growth Factor Reviews 2004, 15:237-254.
45. Bonner J.C. Cytokine & Growth Factor Reviews 2004, 15:255-273.
46. Trojanowska M. Rheumatology (Oxford, England) 2008, 47(Suppl. 5):v2-v4.
47. Board R., Jayson G.C. Drug Resistance Updates 2005, 8:75-83.
48. Ostman A., Heldin C.H. Advances in Cancer Research 2007, 97:247-274.
49. Parsa A.T., Holland E.C. Trends in Molecular Medicine 2004, 10:607-613.
50. Testa J.R., Tsichlis P.N. Oncogene 2005, 24:7391-7393.
51. Peyton K.J., Yu Y., Yates B., Shebib A.R., Liu X.M., Wang H., Durante W. Journal of Pharmacology and Experimental Therapeutics 2011, 338:476-484.
52. Pahara J., Shi H., Chen X., Wang Z. Experimental Cell Research 2010, 316:2237-2250.
53. Emerling B.M., Viollet B., Tormos K.V., Chandel N.S. FEBS Letters 2007, 581:5727-5731.
54. Vucicevic L., Misirkic M., Janjetovic K., Vilimanovich U., Sudar E., Isenovic E., Prica M., Harhaji-Trajkovic L., Kravic-Stevovic T., Bumbasirevic V., Trajkovic V. Autophagy 2010, 7:40-50.
55. Kim Y.M., Kim M.Y., Kim H.J., Roh G.S., Ko G.H., Seo H.G., Lee J.H., Chang K.C. Atherosclerosis 2011, 219:57-64.
56. Bain J., Plater L., Elliott M., Shpiro N., Hastie C.J., McLauchlan H., Klevernic I., Arthur J.S., Alessi D.R., Cohen P. The Biochemical Journal 2007, 408:297-315.
57. Baker S.D., Sparreboom A., Verweij J. Clinical Pharmacokinetics 2006, 45:235-252.
58. Lyseng-Williamson K.A., Fenton C. Drugs 2005, 65:2513-2531.
59. Park E.S., Yoo J.M., Lim Y., Tudev M., Yoo H.S., Hong J.T., Yun Y.P. Journal of Pharmacological Sciences 2011, 116:204-213.
60. Peairs A., Radjavi A., Davis S., Li L., Ahmed A., Giri S., Reilly C.M. Clinical and Experimental Immunology 2009, 156:542-551.
61. Jhun B.S., Jin Q., Oh Y.T., Kim S.S., Kong Y., Cho Y.H., Ha J., Baik H.H., Kang I. Biochemical and Biophysical Research Communications 2004, 318:372-380.