메뉴 건너뛰기




Volumn 48, Issue 3, 2013, Pages 305-312

Cytomegalovirus (CMV)-dependent and -independent changes in the aging of the human immune system: A transcriptomic analysis

Author keywords

Cytomegalovirus; Immunosenescence; Nonagenarians; Pathway analysis; Transcriptomic analysis

Indexed keywords

MESSENGER RNA; RNA;

EID: 84873288253     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2012.12.010     Document Type: Article
Times cited : (18)

References (56)
  • 1
    • 84863094641 scopus 로고    scopus 로고
    • Age-dependent increase of memory B cell response to cytomegalovirus in healthy adults
    • Aberle J.H., Puchhammer-Stöckl E. Age-dependent increase of memory B cell response to cytomegalovirus in healthy adults. Exp. Gerontol. 2012, 47:654-657.
    • (2012) Exp. Gerontol. , vol.47 , pp. 654-657
    • Aberle, J.H.1    Puchhammer-Stöckl, E.2
  • 3
    • 14744281718 scopus 로고    scopus 로고
    • Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons
    • Almanzar G., Schwaiger S., Jenewein B., Keller M., Herndler-Brandstetter D., Würzner R., Schönitzer D., Grubeck-Loebenstein B. Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons. J. Virol. 2005, 79:3675-3683.
    • (2005) J. Virol. , vol.79 , pp. 3675-3683
    • Almanzar, G.1    Schwaiger, S.2    Jenewein, B.3    Keller, M.4    Herndler-Brandstetter, D.5    Würzner, R.6    Schönitzer, D.7    Grubeck-Loebenstein, B.8
  • 5
    • 79953112441 scopus 로고    scopus 로고
    • Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiation
    • Baracho G.V., Miletic A.V., Omori S.A., Cato M.H., Rickert R.C. Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiation. Curr. Opin. Immunol. 2011, 23:178-183.
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 178-183
    • Baracho, G.V.1    Miletic, A.V.2    Omori, S.A.3    Cato, M.H.4    Rickert, R.C.5
  • 7
    • 77950858633 scopus 로고    scopus 로고
    • Cytolytic CD4 cells: direct mediators in infectious disease and malignancy
    • Brown D.M. Cytolytic CD4 cells: direct mediators in infectious disease and malignancy. Cell. Immunol. 2010, 262:89-95.
    • (2010) Cell. Immunol. , vol.262 , pp. 89-95
    • Brown, D.M.1
  • 9
    • 79952022410 scopus 로고    scopus 로고
    • Omega-3 fatty acids and inflammatory processes
    • Calder P.C. Omega-3 fatty acids and inflammatory processes. Nutrients 2010, 2:355-374.
    • (2010) Nutrients , vol.2 , pp. 355-374
    • Calder, P.C.1
  • 10
    • 0027140283 scopus 로고
    • Unexpected expansions of CD8-bearing cells in old mice
    • Callahan J.E., Kappler J.W., Marrack P. Unexpected expansions of CD8-bearing cells in old mice. J. Immunol. 1993, 151:6657-6669.
    • (1993) J. Immunol. , vol.151 , pp. 6657-6669
    • Callahan, J.E.1    Kappler, J.W.2    Marrack, P.3
  • 14
    • 33646518593 scopus 로고    scopus 로고
    • Inflammation markers predicting frailty and mortality in the elderly
    • De Martinis M., Franceschi C., Monti D., Ginaldi L. Inflammation markers predicting frailty and mortality in the elderly. Exp. Mol. Pathol. 2006, 80:219-227.
    • (2006) Exp. Mol. Pathol. , vol.80 , pp. 219-227
    • De Martinis, M.1    Franceschi, C.2    Monti, D.3    Ginaldi, L.4
  • 15
    • 84856844011 scopus 로고    scopus 로고
    • Defective CD8 T cell responses in aged mice are due to quantitative and qualitative changes in virus-specific precursors
    • Decman V., Laidlaw B.J., Doering T.A., Leng J., Ertl H.C., Goldstein D.R., Wherry E.J. Defective CD8 T cell responses in aged mice are due to quantitative and qualitative changes in virus-specific precursors. J. Immunol. 2012, 188:1933-1941.
    • (2012) J. Immunol. , vol.188 , pp. 1933-1941
    • Decman, V.1    Laidlaw, B.J.2    Doering, T.A.3    Leng, J.4    Ertl, H.C.5    Goldstein, D.R.6    Wherry, E.J.7
  • 18
    • 64049095240 scopus 로고    scopus 로고
    • TREM and TREM-like receptors in inflammation and disease
    • Ford J.W., McVicar D.W. TREM and TREM-like receptors in inflammation and disease. Curr. Opin. Immunol. 2009, 21:38-46.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 38-46
    • Ford, J.W.1    McVicar, D.W.2
  • 19
    • 39649085837 scopus 로고    scopus 로고
    • Inflammaging as a major characteristic of old people: can it be prevented or cured?
    • Franceschi C. Inflammaging as a major characteristic of old people: can it be prevented or cured?. Nutr. Rev. 2007, 65:S173-S176.
    • (2007) Nutr. Rev. , vol.65
    • Franceschi, C.1
  • 22
    • 0038044873 scopus 로고    scopus 로고
    • Medical history, cognitive status and mobility at the age of 90. A population-based study in Tampere, Finland
    • Goebeler S., Jylhä M., Hervonen A. Medical history, cognitive status and mobility at the age of 90. A population-based study in Tampere, Finland. Aging Clin. Exp. Res. 2003, 15:154-161.
    • (2003) Aging Clin. Exp. Res. , vol.15 , pp. 154-161
    • Goebeler, S.1    Jylhä, M.2    Hervonen, A.3
  • 24
  • 26
    • 1042300031 scopus 로고    scopus 로고
    • Continuous cytomegalovirus seroconversion in a large group of healthy blood donors
    • Hecker M., Qiu D., Marquardt K., Bein G., Hackstein H. Continuous cytomegalovirus seroconversion in a large group of healthy blood donors. Vox Sang. 2004, 86:41-44.
    • (2004) Vox Sang. , vol.86 , pp. 41-44
    • Hecker, M.1    Qiu, D.2    Marquardt, K.3    Bein, G.4    Hackstein, H.5
  • 27
    • 79955017145 scopus 로고    scopus 로고
    • Human cytomegalovirus immunity and immune evasion
    • Jackson S.E., Mason G.M., Wills M.R. Human cytomegalovirus immunity and immune evasion. Virus Res. 2011, 157:151-160.
    • (2011) Virus Res. , vol.157 , pp. 151-160
    • Jackson, S.E.1    Mason, G.M.2    Wills, M.R.3
  • 28
    • 0028227003 scopus 로고
    • Antibodies are not essential for the resolution of primary cytomegalovirus infection but limit dissemination of recurrent virus
    • Jonjić S., Pavić I., Polić B., Crnković I., Lućin P., Koszinowski U.H. Antibodies are not essential for the resolution of primary cytomegalovirus infection but limit dissemination of recurrent virus. J. Exp. Med. 1994, 179:1713-1717.
    • (1994) J. Exp. Med. , vol.179 , pp. 1713-1717
    • Jonjić, S.1    Pavić, I.2    Polić, B.3    Crnković, I.4    Lućin, P.5    Koszinowski, U.H.6
  • 32
    • 79955955068 scopus 로고    scopus 로고
    • Impact of age on T cell signaling: a general defect or specific alterations?
    • Larbi A., Pawelec G., Wong S.C., Goldeck D., Tai J.J., Fulop T. Impact of age on T cell signaling: a general defect or specific alterations?. Ageing Res. Rev. 2011, 10:370-378.
    • (2011) Ageing Res. Rev. , vol.10 , pp. 370-378
    • Larbi, A.1    Pawelec, G.2    Wong, S.C.3    Goldeck, D.4    Tai, J.J.5    Fulop, T.6
  • 33
    • 11144267995 scopus 로고    scopus 로고
    • Age-related loss of naïve T cells and dysregulation of T-cell/B-cell interactions in human lymph nodes
    • Lazuardi L., Jenewein B., Wolf A.M., Pfister G., Tzankov A., Grubeck-Loebenstein B. Age-related loss of naïve T cells and dysregulation of T-cell/B-cell interactions in human lymph nodes. Immunology 2005, 114:37-43.
    • (2005) Immunology , vol.114 , pp. 37-43
    • Lazuardi, L.1    Jenewein, B.2    Wolf, A.M.3    Pfister, G.4    Tzankov, A.5    Grubeck-Loebenstein, B.6
  • 34
    • 75649127963 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptors and signal transduction
    • Miyazono K., Kamiya Y., Morikawa M. Bone morphogenetic protein receptors and signal transduction. J. Biochem. 2010, 147:35-51.
    • (2010) J. Biochem. , vol.147 , pp. 35-51
    • Miyazono, K.1    Kamiya, Y.2    Morikawa, M.3
  • 35
    • 0035098881 scopus 로고    scopus 로고
    • Molecular pathways in virus-induced cytokine production
    • Mogensen T.H., Paludan S.R. Molecular pathways in virus-induced cytokine production. Microbiol. Mol. Biol. Rev. 2001, 65:131-150.
    • (2001) Microbiol. Mol. Biol. Rev. , vol.65 , pp. 131-150
    • Mogensen, T.H.1    Paludan, S.R.2
  • 36
    • 84859328250 scopus 로고    scopus 로고
    • Early-life environment influencing susceptibility to cytomegalovirus infection: evidence from the Leiden Longevity Study and the Longitudinal Study of Aging Danish Twins
    • Mortensen L.H., Maier A.B., Slagbom P.E., Pawelec G., Derhovanessian E., Petersen I., Jahn G., Westendorp R.G.J., Christensen K. Early-life environment influencing susceptibility to cytomegalovirus infection: evidence from the Leiden Longevity Study and the Longitudinal Study of Aging Danish Twins. Epidemiol. Infect. 2012, 140:835-841.
    • (2012) Epidemiol. Infect. , vol.140 , pp. 835-841
    • Mortensen, L.H.1    Maier, A.B.2    Slagbom, P.E.3    Pawelec, G.4    Derhovanessian, E.5    Petersen, I.6    Jahn, G.7    Westendorp, R.G.J.8    Christensen, K.9
  • 37
    • 33751527236 scopus 로고    scopus 로고
    • Immunity and ageing in man
    • Pawelec G. Immunity and ageing in man. Exp. Gerontol. 2006, 41:1239-1242.
    • (2006) Exp. Gerontol. , vol.41 , pp. 1239-1242
    • Pawelec, G.1
  • 41
    • 77955874092 scopus 로고    scopus 로고
    • Cytomegalovirus antibody levels, inflammation, and mortality among elderly latinos over 9years of follow-up
    • Roberts E.T., Haan M.N., Dowd J.B., Aiello A.E. Cytomegalovirus antibody levels, inflammation, and mortality among elderly latinos over 9years of follow-up. Am. J. Epidemiol. 2009, 172:363-371.
    • (2009) Am. J. Epidemiol. , vol.172 , pp. 363-371
    • Roberts, E.T.1    Haan, M.N.2    Dowd, J.B.3    Aiello, A.E.4
  • 42
    • 65349092347 scopus 로고    scopus 로고
    • Dendritic cells in cytomegalovirus infection: viral evasion and host countermeasures
    • Rölle A., Olweus J. Dendritic cells in cytomegalovirus infection: viral evasion and host countermeasures. APMIS 2009, 117:413-426.
    • (2009) APMIS , vol.117 , pp. 413-426
    • Rölle, A.1    Olweus, J.2
  • 45
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
    • Serhan C.N., Chiang N., Van Dyke T.E. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 2008, 8:349-361.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 46
    • 77951975952 scopus 로고    scopus 로고
    • Diet-induced docosahexaenoic acid non-raft domains and lymphocyte function
    • Shaikh S.R. Diet-induced docosahexaenoic acid non-raft domains and lymphocyte function. Prostaglandins Leukot. Essent. Fat. Acids 2010, 82:159-164.
    • (2010) Prostaglandins Leukot. Essent. Fat. Acids , vol.82 , pp. 159-164
    • Shaikh, S.R.1
  • 47
    • 52949142215 scopus 로고    scopus 로고
    • From expression to signaling: roles of TREM-1 and TREM-2 in innate immunity and bacterial infection
    • Sharif O., Knapp S. From expression to signaling: roles of TREM-1 and TREM-2 in innate immunity and bacterial infection. Immunobiology 2008, 213:701-713.
    • (2008) Immunobiology , vol.213 , pp. 701-713
    • Sharif, O.1    Knapp, S.2
  • 48
    • 79951899662 scopus 로고    scopus 로고
    • Seropositivity to cytomegalovirus, inflammation, all-cause and cardiovascular disease-related mortality in United States
    • Simanek A.M., Dowd J.B., Pawelec G., Melzer D., Dutta A., Aiello A.E. Seropositivity to cytomegalovirus, inflammation, all-cause and cardiovascular disease-related mortality in United States. PLoS One 2011, 6:e16103.
    • (2011) PLoS One , vol.6
    • Simanek, A.M.1    Dowd, J.B.2    Pawelec, G.3    Melzer, D.4    Dutta, A.5    Aiello, A.E.6
  • 49
    • 84868193217 scopus 로고    scopus 로고
    • Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans
    • Solana R., Tarazona R., Gayoso I., Lesur O., Dupuis G., Fulop T. Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans. Semin. Immunol. 2012, 24:331-341.
    • (2012) Semin. Immunol. , vol.24 , pp. 331-341
    • Solana, R.1    Tarazona, R.2    Gayoso, I.3    Lesur, O.4    Dupuis, G.5    Fulop, T.6
  • 50
    • 59249084208 scopus 로고    scopus 로고
    • Cytomegalovirus antibody level and mortality among community-dwelling older adults with stable cardiovascular disease
    • Strandberg T.E., Pitkala K.H., Tilvis R.S. Cytomegalovirus antibody level and mortality among community-dwelling older adults with stable cardiovascular disease. JAMA 2009, 301:380-382.
    • (2009) JAMA , vol.301 , pp. 380-382
    • Strandberg, T.E.1    Pitkala, K.H.2    Tilvis, R.S.3
  • 51
    • 0035076305 scopus 로고    scopus 로고
    • Association of tumour necrosis factor alpha and interleukin 6 levels with cytomegalovirus DNA detection and disease after renal transplantation
    • Tong C.Y., Bakran A., Williams H., Cuevas L.E., Peiris J.S., Hart C.A. Association of tumour necrosis factor alpha and interleukin 6 levels with cytomegalovirus DNA detection and disease after renal transplantation. J. Med. Virol. 2001, 64:29-34.
    • (2001) J. Med. Virol. , vol.64 , pp. 29-34
    • Tong, C.Y.1    Bakran, A.2    Williams, H.3    Cuevas, L.E.4    Peiris, J.S.5    Hart, C.A.6
  • 52
    • 64849088433 scopus 로고    scopus 로고
    • Cutting edge: killer Ig-like receptors mediate "missing self" recognition in vivo
    • van Bergen J., Thompson A., Retière C., Trowsdale J., Koning K. Cutting edge: killer Ig-like receptors mediate "missing self" recognition in vivo. J. Immunol. 2009, 182:2569-2572.
    • (2009) J. Immunol. , vol.182 , pp. 2569-2572
    • van Bergen, J.1    Thompson, A.2    Retière, C.3    Trowsdale, J.4    Koning, K.5
  • 53
    • 67449127131 scopus 로고    scopus 로고
    • Human cytomegalovirus targets different subsets of antigen-presenting cells with pathological consequences for host immunity: implications for immunosuppression, chronic inflammation and autoimmunity
    • Varani S., Frascaroli G., Landini M.P., Söderberg-Nauclér C. Human cytomegalovirus targets different subsets of antigen-presenting cells with pathological consequences for host immunity: implications for immunosuppression, chronic inflammation and autoimmunity. Rev. Med. Virol. 2009, 19:131-145.
    • (2009) Rev. Med. Virol. , vol.19 , pp. 131-145
    • Varani, S.1    Frascaroli, G.2    Landini, M.P.3    Söderberg-Nauclér, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.