메뉴 건너뛰기




Volumn 1114, Issue , 2007, Pages 23-35

Cytomegalovirus infection: A driving force in human T cell immunosenescence

Author keywords

Aging; Cell aging; Cytology; Cytomegalovirus; Cytomegalovirus infections; Humans; Immune system; Immunity; Immunology; Longitudinal studies; Memory; Mortality; Phenotype; Risk factors; T lymphocytes; Virology

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CIDOFOVIR; CYTOMEGALOVIRUS VACCINE; FOSCARNET; GANCICLOVIR; HLA A2 ANTIGEN; T LYMPHOCYTE RECEPTOR; VALGANCICLOVIR;

EID: 35948988938     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1396.043     Document Type: Conference Paper
Times cited : (210)

References (58)
  • 1
    • 0347918850 scopus 로고    scopus 로고
    • Cytomegalovirus infection in immunocompetent patients
    • WREGHITT, T.G., E.L. TEARE, O. SULE, et al. 2003. Cytomegalovirus infection in immunocompetent patients. Clin. Infect. Dis. 37: 1603-1606.
    • (2003) Clin. Infect. Dis , vol.37 , pp. 1603-1606
    • WREGHITT, T.G.1    TEARE, E.L.2    SULE, O.3
  • 2
    • 17644374153 scopus 로고    scopus 로고
    • Meta-analysis of outcome of cytomegalovirus colitis in immunocompetent hosts
    • GALIATSATOS, P., I. SHRIER, E. LAMOUREUX & A. SZILAGYI. 2005. Meta-analysis of outcome of cytomegalovirus colitis in immunocompetent hosts. Dig. Dis. Sci. 50: 609-616.
    • (2005) Dig. Dis. Sci , vol.50 , pp. 609-616
    • GALIATSATOS, P.1    SHRIER, I.2    LAMOUREUX, E.3    SZILAGYI, A.4
  • 3
    • 33846955443 scopus 로고    scopus 로고
    • + T cell populations reveals sustained, functional and mature responses. Immun. Ageing 3: 11.
    • + T cell populations reveals sustained, functional and mature responses. Immun. Ageing 3: 11.
  • 4
    • 0035915757 scopus 로고    scopus 로고
    • Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: The Swedish longitudinal OCTO immune study
    • OLSSON, J., A. WIKBY, B. JOHANSSON, et al. 2000. Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: the Swedish longitudinal OCTO immune study Mech. Ageing Dev. 121: 187-201.
    • (2000) Mech. Ageing Dev , vol.121 , pp. 187-201
    • OLSSON, J.1    WIKBY, A.2    JOHANSSON, B.3
  • 5
    • 0037103256 scopus 로고    scopus 로고
    • Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals
    • KHAN, N., N. SHARIFF, M. COBBOLD, et al. 2002. Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals. J. Immunol. 169: 1984-1992.
    • (2002) J. Immunol , vol.169 , pp. 1984-1992
    • KHAN, N.1    SHARIFF, N.2    COBBOLD, M.3
  • 6
    • 0036604316 scopus 로고    scopus 로고
    • Identification of naive or antigen-experienced human CD8(+) T cells by expression of costimulation and chemokine receptors: Analysis of the human cytomegalovirus-specific CD8(+) T cell response
    • WILLS, M.R., G. OKECHA, M.P. WEEKES, et al. 2002. Identification of naive or antigen-experienced human CD8(+) T cells by expression of costimulation and chemokine receptors: analysis of the human cytomegalovirus-specific CD8(+) T cell response. J. Immunol. 168: 5455-5464.
    • (2002) J. Immunol , vol.168 , pp. 5455-5464
    • WILLS, M.R.1    OKECHA, G.2    WEEKES, M.P.3
  • 7
    • 0035876923 scopus 로고    scopus 로고
    • Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: Implications of a novel approach for T cell monitoring in infectious and malignant diseases
    • PITTET, M.J., A. ZIPPELIUS, D.E. SPEISER, et al. 2001. Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases. J. Immunol. 166: 7634-7640.
    • (2001) J. Immunol , vol.166 , pp. 7634-7640
    • PITTET, M.J.1    ZIPPELIUS, A.2    SPEISER, D.E.3
  • 8
    • 0029743737 scopus 로고    scopus 로고
    • Phenotypic analysis of antigen-specific T lymphocytes
    • ALTMAN, J.D., P.A. MOSS, P.J. GOULDER, et al. 1996. Phenotypic analysis of antigen-specific T lymphocytes. Science 274: 94-96.
    • (1996) Science , vol.274 , pp. 94-96
    • ALTMAN, J.D.1    MOSS, P.A.2    GOULDER, P.J.3
  • 11
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory T cell subsets: Function, generation, and maintenance
    • SALLUSTO, F., J. GEGINAT & A. LANZAVECCHIA. 2004. Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu. Rev. Immunol. 22: 745-763.
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 745-763
    • SALLUSTO, F.1    GEGINAT, J.2    LANZAVECCHIA, A.3
  • 12
    • 33646161724 scopus 로고    scopus 로고
    • Human cytomegalovirus infection and T cell immunosenescence: A mini review
    • KOCH, S., R. SOLANA, R.O. DELA & G. PAWELEC. 2006. Human cytomegalovirus infection and T cell immunosenescence: a mini review. Mech. Ageing Dev. 127: 538-543.
    • (2006) Mech. Ageing Dev , vol.127 , pp. 538-543
    • KOCH, S.1    SOLANA, R.2    DELA, R.O.3    PAWELEC, G.4
  • 13
    • 0041941144 scopus 로고    scopus 로고
    • + T subsets with distinct replicative history and partial effector functions
    • + T subsets with distinct replicative history and partial effector functions. Blood 102: 1779-1787.
    • (2003) Blood , vol.102 , pp. 1779-1787
    • RUFER, N.1    ZIPPELIUS, A.2    BATARD, P.3
  • 14
    • 0036604205 scopus 로고    scopus 로고
    • Differentiation of human CD8(+) T cells from a memory to memory/effector phenotype
    • TOMIYAMA, H., T. MATSUDA & M. TAKIGUCHI. 2002. Differentiation of human CD8(+) T cells from a memory to memory/effector phenotype. J. Immunol. 168: 5538-5550.
    • (2002) J. Immunol , vol.168 , pp. 5538-5550
    • TOMIYAMA, H.1    MATSUDA, T.2    TAKIGUCHI, M.3
  • 16
    • 33646546302 scopus 로고    scopus 로고
    • Aging of the immune system: Howmuch can the adaptive immune system adapt?
    • WENG, N.P. 2006. Aging of the immune system: howmuch can the adaptive immune system adapt? Immunity 24: 495-499.
    • (2006) Immunity , vol.24 , pp. 495-499
    • WENG, N.P.1
  • 17
    • 0033844364 scopus 로고    scopus 로고
    • The increase of IFN-gamma production through aging correlates with the expanded CD8(+high)CD28 (-)CD57(+) subpopulation
    • BANDRES, E., J. MERINO, B. VAZQUEZ, et al. 2000. The increase of IFN-gamma production through aging correlates with the expanded CD8(+high)CD28 (-)CD57(+) subpopulation. Clin. Immunol. 96: 230-235.
    • (2000) Clin. Immunol , vol.96 , pp. 230-235
    • BANDRES, E.1    MERINO, J.2    VAZQUEZ, B.3
  • 18
    • 16344374892 scopus 로고    scopus 로고
    • Does memory improve with age? CD85j (ILT-2/LIR-1) expression on CD8 T cells correlates with 'memory inflation' in human cytomegalovirus infection
    • NORTHFIELD, J., M. LUCAS, H. JONES, et al. 2005. Does memory improve with age? CD85j (ILT-2/LIR-1) expression on CD8 T cells correlates with 'memory inflation' in human cytomegalovirus infection Immunol. Cell Biol. 83: 182-188.
    • (2005) Immunol. Cell Biol , vol.83 , pp. 182-188
    • NORTHFIELD, J.1    LUCAS, M.2    JONES, H.3
  • 19
    • 0042206627 scopus 로고    scopus 로고
    • + T cells expressing the inhibitory killer cell lectin-like receptor G1 (KLRG1)
    • + T cells expressing the inhibitory killer cell lectin-like receptor G1 (KLRG1). Exp. Gerontol. 38: 911-920.
    • (2003) Exp. Gerontol , vol.38 , pp. 911-920
    • OUYANG, Q.1    WAGNER, W.M.2    VOEHRINGER, D.3
  • 21
    • 10344257508 scopus 로고    scopus 로고
    • Herpesvirus-specific CD8 T Cell immunity in old age: Cytomegalovirus impairs the response to a coresident EBV infection
    • KHAN, N., A. HISLOP, N. GUDGEON, et al. 2004. Herpesvirus-specific CD8 T Cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection. J. Immunol. 173: 7481-7489.
    • (2004) J. Immunol , vol.173 , pp. 7481-7489
    • KHAN, N.1    HISLOP, A.2    GUDGEON, N.3
  • 22
    • 0037825764 scopus 로고    scopus 로고
    • + T lymphocytes bearing receptors for a single dominant CMV epitope in the very old
    • + T lymphocytes bearing receptors for a single dominant CMV epitope in the very old. J. Clin. Immunol. 23: 247-257.
    • (2003) J. Clin. Immunol , vol.23 , pp. 247-257
    • OUYANG, Q.1    WAGNER, W.M.2    WIKBY, A.3
  • 23
    • 1642503829 scopus 로고    scopus 로고
    • Dysfunctional CMV-specific CD8(+) T cells accumulate in the elderly
    • OUYANG, Q., W.M. WAGNER, W. ZHENG, et al. 2004. Dysfunctional CMV-specific CD8(+) T cells accumulate in the elderly. Exp. Gerontol. 39: 607-613.
    • (2004) Exp. Gerontol , vol.39 , pp. 607-613
    • OUYANG, Q.1    WAGNER, W.M.2    ZHENG, W.3
  • 24
    • 0037111658 scopus 로고    scopus 로고
    • Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1)
    • VOEHRINGER, D., M. KOSCHELLA & H. PIRCHER. 2002. Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1). Blood 100: 3698-3702.
    • (2002) Blood , vol.100 , pp. 3698-3702
    • VOEHRINGER, D.1    KOSCHELLA, M.2    PIRCHER, H.3
  • 25
    • 33646356509 scopus 로고    scopus 로고
    • Immunosenescence, suppression and tumour progression
    • PAWELEC, G., S. KOCH, H. GRIESEMANN, et al. 2006. Immunosenescence, suppression and tumour progression. Cancer Immunol. Immunother. 55: 981-986.
    • (2006) Cancer Immunol. Immunother , vol.55 , pp. 981-986
    • PAWELEC, G.1    KOCH, S.2    GRIESEMANN, H.3
  • 27
    • 18644378123 scopus 로고    scopus 로고
    • + T lymphocytes during active, latent, and resolved infection and its relation with CD57
    • + T lymphocytes during active, latent, and resolved infection and its relation with CD57. J. Immunol. 174: 6088-6094.
    • (2005) J. Immunol , vol.174 , pp. 6088-6094
    • IBEGBU, C.C.1    XU, Y.X.2    HARRIS, W.3
  • 28
    • 0037012021 scopus 로고    scopus 로고
    • Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: The Swedish NONA immune study
    • WIKBY, A., B. JOHANSSON, J. OLSSON, et al. 2002. Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study. Exp. Gerontol. 37: 445-453.
    • (2002) Exp. Gerontol , vol.37 , pp. 445-453
    • WIKBY, A.1    JOHANSSON, B.2    OLSSON, J.3
  • 29
    • 20344396835 scopus 로고    scopus 로고
    • Human immunosenescence: Is it infectious?
    • PAWELEC, G., A. AKBAR, C. CARUSO, et al. 2005. Human immunosenescence: is it infectious? Immunol. Rev. 205: 257-268.
    • (2005) Immunol. Rev , vol.205 , pp. 257-268
    • PAWELEC, G.1    AKBAR, A.2    CARUSO, C.3
  • 30
    • 32044433093 scopus 로고    scopus 로고
    • Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly
    • HADRUP, S.R., J. STRINDHALL, T. KOLLGAARD, et al. 2006. Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly. J. Immunol. 176: 2645-2653.
    • (2006) J. Immunol , vol.176 , pp. 2645-2653
    • HADRUP, S.R.1    STRINDHALL, J.2    KOLLGAARD, T.3
  • 31
    • 33745451585 scopus 로고    scopus 로고
    • The immune risk phenotype is associated with IL-6 in the terminal decline stage: Findings from the Swedish NONA immune longitudinal study of very late life functioning
    • WIKBY, A., B.O. NILSSON, R. FORSEY, et al. 2006. The immune risk phenotype is associated with IL-6 in the terminal decline stage: findings from the Swedish NONA immune longitudinal study of very late life functioning. Mech. Ageing Dev. 127: 695-704.
    • (2006) Mech. Ageing Dev , vol.127 , pp. 695-704
    • WIKBY, A.1    NILSSON, B.O.2    FORSEY, R.3
  • 32
    • 34447319921 scopus 로고    scopus 로고
    • STRINDHALL, J., B.O. NILSSON, S. LOFGREN, et al. 2007. No immune risk profile among individuals who reach 100 years of age: findings from the Swedish NONA immune longitudinal study. Exp. Gerontol. May 21 [Epub ahead of print].
    • STRINDHALL, J., B.O. NILSSON, S. LOFGREN, et al. 2007. No immune risk profile among individuals who reach 100 years of age: findings from the Swedish NONA immune longitudinal study. Exp. Gerontol. May 21 [Epub ahead of print].
  • 34
    • 0037397637 scopus 로고    scopus 로고
    • + T cells carrying receptors for an immunodominant Epstein-Barr virus (EBV) epitope is counteracted by a decreased frequency of their antigen-specific responsiveness
    • + T cells carrying receptors for an immunodominant Epstein-Barr virus (EBV) epitope is counteracted by a decreased frequency of their antigen-specific responsiveness. Mech. Ageing Dev. 124: 477-485.
    • (2003) Mech. Ageing Dev , vol.124 , pp. 477-485
    • OUYANG, Q.1    WAGNER, W.M.2    WALTER, S.3
  • 35
    • 20544476197 scopus 로고    scopus 로고
    • An immune risk phenotype, cognitive impairment, and survival in very late life: Impact of allostatic load in Swedish octogenarian and nonagenarian humans
    • WIKBY, A., F. FERGUSON, R. FORSEY, et al. 2005. An immune risk phenotype, cognitive impairment, and survival in very late life: impact of allostatic load in Swedish octogenarian and nonagenarian humans. J. Gerontol. A Biol. Sci. Med. Sci. 60: 556-565.
    • (2005) J. Gerontol. A Biol. Sci. Med. Sci , vol.60 , pp. 556-565
    • WIKBY, A.1    FERGUSON, F.2    FORSEY, R.3
  • 36
    • 0037406559 scopus 로고    scopus 로고
    • Immune response to influenza vaccination in an elderly population
    • BRYDAK, L.B., M. MACHALA, J. MYSLIWSKA, et al. 2003. Immune response to influenza vaccination in an elderly population. J. Clin. Immunol. 23: 214-222.
    • (2003) J. Clin. Immunol , vol.23 , pp. 214-222
    • BRYDAK, L.B.1    MACHALA, M.2    MYSLIWSKA, J.3
  • 37
    • 0242317690 scopus 로고    scopus 로고
    • Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination: An impact of immunosenescence
    • TRZONKOWSKI, P., J. MYSLIWSKA, E. SZMIT, et al. 2003. Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination: an impact of immunosenescence. Vaccine 21: 3826-3836.
    • (2003) Vaccine , vol.21 , pp. 3826-3836
    • TRZONKOWSKI, P.1    MYSLIWSKA, J.2    SZMIT, E.3
  • 38
    • 0031461818 scopus 로고    scopus 로고
    • The influence of cytomegalovirus on the natural history of HIV infection: Evidence of rapid course of HIV infection in HIV-positive patients infected with cytomegalovirus
    • SINICCO, A., R. RAITERI, M. SCIANDRA, et al. 1997. The influence of cytomegalovirus on the natural history of HIV infection: evidence of rapid course of HIV infection in HIV-positive patients infected with cytomegalovirus. Scand. J. Infect. Dis. 29: 543-549.
    • (1997) Scand. J. Infect. Dis , vol.29 , pp. 543-549
    • SINICCO, A.1    RAITERI, R.2    SCIANDRA, M.3
  • 40
    • 0037097657 scopus 로고    scopus 로고
    • Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals
    • KERN, F., T. BUNDE, N. FAULHABER, et al. 2002. Cytomegalovirus (CMV) phosphoprotein 65 makes a large contribution to shaping the T cell repertoire in CMV-exposed individuals. J. Infect. Dis. 185: 1709-1716.
    • (2002) J. Infect. Dis , vol.185 , pp. 1709-1716
    • KERN, F.1    BUNDE, T.2    FAULHABER, N.3
  • 41
    • 11844258837 scopus 로고    scopus 로고
    • Generation of cytomegalovirus (CMV)-specific CD4 T cell lines devoid of alloreactivity, by use of a mixture of CMV-phosphoprotein 65 peptides for reconstitution of the T helper repertoire
    • LI, P.G., L. BOTTONE, F. IVALDI, et al. 2005. Generation of cytomegalovirus (CMV)-specific CD4 T cell lines devoid of alloreactivity, by use of a mixture of CMV-phosphoprotein 65 peptides for reconstitution of the T helper repertoire. J. Infect. Dis. 191: 215-226.
    • (2005) J. Infect. Dis , vol.191 , pp. 215-226
    • LI, P.G.1    BOTTONE, L.2    IVALDI, F.3
  • 42
    • 0036198286 scopus 로고    scopus 로고
    • Sustained high frequencies of specific CD4 T cells restricted to a single persistent virus
    • SESTER, M., U. SESTER, B. GARTNER, et al. 2002. Sustained high frequencies of specific CD4 T cells restricted to a single persistent virus. J. Virol. 76: 3748-3755.
    • (2002) J. Virol , vol.76 , pp. 3748-3755
    • SESTER, M.1    SESTER, U.2    GARTNER, B.3
  • 43
    • 6344241638 scopus 로고    scopus 로고
    • + T cell clones specific for human cytomegalovirus are distributed in both CD45RAhigh and CD45ROhigh populations
    • + T cell clones specific for human cytomegalovirus are distributed in both CD45RAhigh and CD45ROhigh populations. J. Immunol. 173: 5843-5851.
    • (2004) J. Immunol , vol.173 , pp. 5843-5851
    • WEEKES, M.P.1    WILLS, M.R.2    SISSONS, J.G.3    CARMICHAEL, A.J.4
  • 44
    • 0036604438 scopus 로고    scopus 로고
    • Characterization of CD4(+) CTLs ex vivo
    • APPAY, V., J.J. ZAUNDERS, L. PAPAGNO, et al. 2002. Characterization of CD4(+) CTLs ex vivo. J. Immunol. 168: 5954-5958.
    • (2002) J. Immunol , vol.168 , pp. 5954-5958
    • APPAY, V.1    ZAUNDERS, J.J.2    PAPAGNO, L.3
  • 46
    • 3242748853 scopus 로고    scopus 로고
    • +CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection
    • +CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection. J. Immunol. 173: 1834-1841.
    • (2004) J. Immunol , vol.173 , pp. 1834-1841
    • VAN LEEUWEN, E.M.1    REMMERSWAAL, E.B.2    VOSSEN, M.T.3
  • 47
    • 29144435156 scopus 로고    scopus 로고
    • + T cells in healthy carriers are continuously driven to replicative exhaustion
    • + T cells in healthy carriers are continuously driven to replicative exhaustion. J. Immunol. 175: 8218-8225.
    • (2005) J. Immunol , vol.175 , pp. 8218-8225
    • FLETCHER, J.M.1    VUKMANOVIC-STEJIC, M.2    DUNNE, P.J.3
  • 48
    • 2442418917 scopus 로고    scopus 로고
    • The size and phenotype of virus-specific T cell populations is determined by repetitive antigenic stimulation and environmental cytokines
    • GAMADIA, L.E., E.M. VAN LEEUWEN, E.B. REMMERSWAAL, et al. 2004. The size and phenotype of virus-specific T cell populations is determined by repetitive antigenic stimulation and environmental cytokines. J. Immunol. 172: 6107-6114.
    • (2004) J. Immunol , vol.172 , pp. 6107-6114
    • GAMADIA, L.E.1    VAN LEEUWEN, E.M.2    REMMERSWAAL, E.B.3
  • 49
    • 0038600612 scopus 로고    scopus 로고
    • Antenatal and perinatal strategies to prevent mother-to-child transmission of HIV infection
    • NEWELL, M.L. 2003. Antenatal and perinatal strategies to prevent mother-to-child transmission of HIV infection. Trans. R. Soc. Trop. Med. Hyg. 97: 22-24.
    • (2003) Trans. R. Soc. Trop. Med. Hyg , vol.97 , pp. 22-24
    • NEWELL, M.L.1
  • 50
    • 3042821777 scopus 로고    scopus 로고
    • Cytomegalovirus (CMV) inactivation in breast milk: Reassessment of pasteurization and freeze-thawing
    • HAMPRECHT, K., J. MASCHMANN, D. MULLER, et al. 2004. Cytomegalovirus (CMV) inactivation in breast milk: reassessment of pasteurization and freeze-thawing. Pediatr. Res. 56: 529-535.
    • (2004) Pediatr. Res , vol.56 , pp. 529-535
    • HAMPRECHT, K.1    MASCHMANN, J.2    MULLER, D.3
  • 51
    • 33747141729 scopus 로고    scopus 로고
    • Antiviral drugs for cytomegalovirus diseases
    • BIRON, K.K. 2006. Antiviral drugs for cytomegalovirus diseases. Antiviral Res. 71: 154-163.
    • (2006) Antiviral Res , vol.71 , pp. 154-163
    • BIRON, K.K.1
  • 52
    • 33748947326 scopus 로고    scopus 로고
    • PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
    • DAY, C.L., D.E. KAUFMANN, P. KIEPIELA, et al. 2006. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443: 350-354.
    • (2006) Nature , vol.443 , pp. 350-354
    • DAY, C.L.1    KAUFMANN, D.E.2    KIEPIELA, P.3
  • 54
    • 34047172640 scopus 로고    scopus 로고
    • IL-10, T cell exhaustion and viral persistence
    • BLACKBURN, S.D. & E.J. WHERRY. 2007. IL-10, T cell exhaustion and viral persistence. Trends Microbiol. 15: 143-146.
    • (2007) Trends Microbiol , vol.15 , pp. 143-146
    • BLACKBURN, S.D.1    WHERRY, E.J.2
  • 55
    • 33750499311 scopus 로고    scopus 로고
    • Interleukin-10 determines viral clearance or persistence in vivo
    • BROOKS, D.G., M.J. TRIFILO, K.H. EDELMANN, et al. 2006. Interleukin-10 determines viral clearance or persistence in vivo. Nat. Med. 12: 1301-1309.
    • (2006) Nat. Med , vol.12 , pp. 1301-1309
    • BROOKS, D.G.1    TRIFILO, M.J.2    EDELMANN, K.H.3
  • 56
    • 33750530611 scopus 로고    scopus 로고
    • Resolution of a chronic viral infection after interleukin-10 receptor blockade
    • EJRNAES, M., C.M. FILIPPI, M.M. MARTINIC, et al. 2006. Resolution of a chronic viral infection after interleukin-10 receptor blockade. J. Exp. Med. 203: 2461-2472.
    • (2006) J. Exp. Med , vol.203 , pp. 2461-2472
    • EJRNAES, M.1    FILIPPI, C.M.2    MARTINIC, M.M.3
  • 57
    • 33646141172 scopus 로고    scopus 로고
    • T cell development, ageing and interleukin-7
    • ASPINALL, R. 2006. T cell development, ageing and interleukin-7. Mech. Ageing Dev. 127: 572-578.
    • (2006) Mech. Ageing Dev , vol.127 , pp. 572-578
    • ASPINALL, R.1
  • 58
    • 24744434924 scopus 로고    scopus 로고
    • An IL-7 fusion protein that shows increased thymopoietic ability
    • HENSON, S.M., R. SNELGROVE, T. HUSSELL, et al. 2005. An IL-7 fusion protein that shows increased thymopoietic ability. J. Immunol. 175: 4112-4118.
    • (2005) J. Immunol , vol.175 , pp. 4112-4118
    • HENSON, S.M.1    SNELGROVE, R.2    HUSSELL, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.