Edelfosine and perifosine disrupt hepatic mitochondrial oxidative phosphorylation and induce the permeability transition

Mitochondrion

Volumn 13, Issue 1, 2013, Pages 25-35

  Burgeiro, Ana ^a,b   Pereira, Cláudia V ^a,b   Carvalho, Filipa S ^a,b   Pereira, Gonçalo C ^a,b   Mollinedo, Faustino ^c   Oliveira, Paulo J ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Edelfosine; Liver; Mitochondria; Perifosine; Rat; Toxicity

Indexed keywords

CYCLOSPORIN A; EDELFOSINE; HYDROGEN PEROXIDE; PERIFOSINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTRIC POTENTIAL; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL PERMEABILITY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN;

ANIMALS; ANTINEOPLASTIC AGENTS; HYDROGEN PEROXIDE; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIAL MEMBRANES; OXIDATIVE PHOSPHORYLATION; PERMEABILITY; PHOSPHOLIPID ETHERS; PHOSPHORYLCHOLINE; RATS, WISTAR;

RATTUS;

EID: 84873287256     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2012.11.003     Document Type: Article

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