Can drug safety be predicted and animal experiments reduced by using isolated mitochondrial fractions?

Alternatives to Laboratory Animals

Volumn 37, Issue 4, 2009, Pages 355-365

  Pereira, Susana P ^a   Pereira, Gonçalo C ^a   Moreno, António J ^b   Oliveira, Paulo J ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Animal models; Biosensor; Mitochondria; Toxicity

Indexed keywords

ACUTE TOXICITY; ANIMAL EXPERIMENT; BIOSENSOR; CARCINOGENICITY; CHRONIC TOXICITY; CONFERENCE PAPER; DEVELOPMENTAL DISORDER; DRUG DOSE; DRUG MECHANISM; DRUG SAFETY; ELECTRIC POTENTIAL; LD 50; MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; SCREENING; TOXICITY TESTING; TOXICOLOGY;

ANIMALIA;

EID: 70449604749     PISSN: 02611929     EISSN: None     Source Type: Journal    
DOI: 10.1177/026119290903700406     Document Type: Conference Paper

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