Differential targets and subcellular localization of antitumor alkyl-lysophospholipid in leukemic versus solid tumor cells

Journal of Biological Chemistry

Volumn 281, Issue 21, 2006, Pages 14833-14840

  Nieto Miguel, Teresa ^a   Gajate, Consuelo ^a,b   Mollinedo, Faustino ^a  

^a Centro de Investigacion del Cancer   (Spain)

^b HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; DRUG PRODUCTS; ENZYMES; PHOSPHOLIPIDS; PROTEINS;

ENDOPLASMIC RETICULUM; LEUKEMIC CELLS; LYSOPHOSPHOLIPIDS;

TUMORS;

ALKYLLYSOPHOSPHOLIPID; CASPASE 3; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; EDELFOSINE; FAS ANTIGEN; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL MEMBRANE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG MECHANISM; DRUG METABOLISM; DRUG UPTAKE; ENDOPLASMIC RETICULUM; EPITHELIOID CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SOLID TUMOR; T CELL LEUKEMIA;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASES; ENDOPLASMIC RETICULUM; HELA CELLS; HUMANS; JURKAT CELLS; LEUKEMIA; LYSOPHOSPHOLIPIDS; MAP KINASE KINASE 4; MEMBRANE MICRODOMAINS; NEOPLASMS; PHOSPHOLIPID ETHERS;

EID: 33744957442     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511251200     Document Type: Article

References (57)

1. Houlihan, W. J., Lohmeyer, M., Workman, P., and Cheon, S. H. (1995) Med. Res. Rev. 15, 157-223
2. Gajate, C., and Mollinedo, F. (2002) Curr. Drug. Metab. 3, 491-525
3. Jendrossek, V., and Handrick, R. (2003) Curr. Med. Chem. Anti-Canc. Agents 3, 343-353
4. Mollinedo, F., Gajate, C., Martin-Santamaria, S., and Gago, F. (2004) Curr. Med. Chem. 11, 3163-3184
5. Mollinedo, F., Fernandez-Luna, J. L., Gajate, C., Martin-Martin, B., Benito, A., Martinez-Dalmau, R., and Modolell, M. (1997) Cancer Res. 57, 1320-1328
6. Baburina, I., and Jackowski, S. (1998) J. Biol. Chem. 273, 2169-2173
7. Gajate, C., Del Canto-Janez, E., Acuña, A. U., Amat-Guerri, F., Geijo, E., Santos-Beneit, A. M., Veldman, R. J., and Mollinedo, F. (2004) J. Exp. Med. 200, 353-365
8. Kennedy, E. P., and Weiss, S. B. (1956) J. Biol. Chem. 222, 193-214
9. Kent, C. (1990) Prog. Lipid Res. 29, 87-105
10. Esko, J. D., and Raetz, C. R. (1980) Proc. Natl. Acad. Sci. U. S. A. 77, 5192-5196
11. Esko, J. D., Wermuth, M. M., and Raetz, C. R. (1981) J. Biol. Chem. 256, 7388-7393
12. Lykidis, A., Baburina, I., and Jackowski, S. (1999) J. Biol. Chem. 274, 26992-27001
13. Cornell, R. B., and Northwood, I. C. (2000) Trends Biochem. Sci. 25, 441-447
14. Ridsdale, R., Tseu, I., Wang, J., and Post, M. (2001) J. Biol. Chem. 276, 49148-49155
15. Boggs, K. P., Rock, C. O., and Jackowski, S. (1995) J. Biol. Chem. 270, 7757-7764
16. van der Luit, A. H., Budde, M., Ruurs, P., Verheij, M., and van Blitterswijk, W. J. (2002) J. Biol. Chem. 277, 39541-39547
17. Boggs, K. P., Rock, C. O., and Jackowski, S. (1995) J. Biol. Chem. 270, 11612-11618
18. Gajate, C., Fonteriz, R. I., Cabaner, C., Alvarez-Noves, G., Alvarez-Rodriguez, Y., Modolell, M., and Mollinedo, F. (2000) Int. J. Cancer 85, 674-682
19. Gajate, C., and Mollinedo, F. (2001) Blood 98, 3860-3863
20. Mollinedo, F., and Gajate, C. (2004) in Fas Signaling (Wajant, H., ed), pp. 1-15, Landes Bioscience, Georgetown, TX
21. Gajate, C., Barasoain, I., Andreu, J. M., and Mollinedo, F. (2000) Cancer Res. 60, 2651-2659
22. Hibi, M., Lin, A., Smeal, T., Minden, A., and Karin, M. (1993) Genes Dev. 7, 2135-2148
23. Gajate, C., An, F., and Mollinedo, F. (2002) J. Biol. Chem. 277, 41580-41589
24. Cheng, P. C., Dykstra, M. L., Mitchell, R. N., and Pierce, S. K. (1999) J. Exp. Med. 190, 1549-1560
25. Gabel, B. R., Elwell, C., van Ijzendoorn, S. C., and Engel, J. N. (2004) Infect. Immun. 72, 7367-7373
26. Klee, M., and Pimentel-Muiños, F. X. (2005) J. Cell Biol. 168, 723-734
27. Bligh, E. G., and Dyer, W. J. (1959) Can J. Med. Sci. 37, 911-917
28. Gajate, C., Santos-Beneit, A., Modolell, M., and Mollinedo, F. (1998) Mol. Pharmacol. 53, 602-612
29. Ruiter, G. A., Zerp, S. F., Bartelink, H., van Blitterswijk, W. J., and Verheij, M. (1999) Cancer Res. 59, 2457-2463
30. Gajate, C., Santos-Beneit, A. M., Macho, A., Lazaro, M., Hernandez-De Rojas, A., Modolell, M., Munoz, E., and Mollinedo, F. (2000) Int. J. Cancer 86, 208-218
31. Magistrelli, A., Villa, P., Benfenati, E., Modest, E. J., Salmona, M., and Tacconi, M. T. (1995) Drug Metab. Dispos. 23, 113-118
32. Schon, A., and Freire, E. (1989) Biochemistry 28, 5019-5024
33. Harder, T., Scheiffele, P., Verkade, P., and Simons, K. (1998) J. Cell Biol. 141, 929-942
34. Yang, X., Khosravi-Far, R., Chang, H. Y., and Baltimore, D. (1997) Cell 89, 1067-1076
35. Simons, K., and Toomre, D. (2000) Nat. Rev. Mol. Cell. Biol. 1, 31-39
36. Fra, A. M., Williamson, E., Simons, K., and Parton, R. G. (1994) J. Biol. Chem. 269, 30745-30748
37. Orlandi, P. A., and Fishman, P. H. (1998) J. Cell Biol. 141, 905-915
38. Hoffman, D. R., Thomas, V. L., and Snyder, F. (1992) Biochim. Biophys. Acta 1127, 74-80
39. Zhou, X., and Arthur, G. (1995) Eur. J. Biochem. 232, 881-888
40. Boggs, K., Rock, C. O., and Jackowski, S. (1998) Biochim. Biophys. Acta 1389, 1-12
41. Powis, G., Seewald, M. J., Gratas, C., Melder, D., Riebow, J., and Modest, E. J. (1992) Cancer Res. 52, 2835-2840
42. Kiss, Z., and Crilly, K. S. (1997) FEBS Lett. 412, 313-317
43. Quesada, E., Delgado, J., Gajate, C., Mollinedo, F., Acuña, A. U., and Amat-Guerri, F. (2004) J. Med. Chem. 47, 5333-5335
44. Voelker, D. R., and Kennedy, E. P. (1982) Biochemistry 21, 2753-2759
45. Voelker, D. R. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 2669-2673
46. Jackowski, S. (1996) J. Biol. Chem. 271, 20219-20222
47. Breckenridge, D. G., Germain, M., Mathai, J. P., Nguyen, M., and Shore, G. C. (2003) Oncogene 22, 8608-8618
48. Nishitoh, H., Matsuzawa, A., Tobiume, K., Saegusa, K., Takeda, K., Inoue, K., Hori, S., Kakizuka, A., and Ichijo, H. (2002) Genes Dev. 16, 1345-1355
49. Takeda, K., Matsuzawa, A., Nishitoh, H., and Ichijo, H. (2003) Cell Struct. Funct. 28, 23-29
50. Peter, M. E., and Krammer, P. H. (2003) Cell Death Differ. 10, 26-35
51. Hofmann, T. G., Moller, A., Hehner, S. P., Welsch, D., Droge, W., and Schmitz, M. L. (2001) Int. J. Cancer 93, 185-191
52. Villunger, A., Huang, D. C., Holler, N., Tschopp, J., and Strasser, A. (2000) J. Immunol. 165, 1337-1343
53. Pike, L. J. (2004) Biochem. J. 378, 281-292
54. Manes, S., del Real, G., and Martinez, A. C. (2003) Nat. Rev. Immunol. 3, 557-568
55. Van Der Luit, A. H., Budde, M., Verheij, M., and Van Blitterswijk, W. J. (2003) Biochem. J. 374, 747-753
56. Zaremberg, V., Gajate, C., Cacharro, L. M., Mollinedo, F., and McMaster, C. R. (2005) J. Biol. Chem. 280, 38047-38058
57. Gajate, C., and Mollinedo, F. (2005) J. Biol. Chem. 280, 11641-11647