Osteopontin-dependent regulation of Th1 and Th17 cytokine responses in Trypanosoma cruzi-infected C57BL/6 mice

Cytokine

Volumn 61, Issue 2, 2013, Pages 491-498

  Santamaría, Miguel H ^a   Corral, Ricardo S ^b  

^a Laboratorio de Biologiá Experimental   (Spain)

^b HOSPITAL DE NIÑOS RICARDO GUTIÉRREZ   (Argentina)

Author keywords

Chagas disease; Osteopontin; Protective immunity; Th1 Th17 cytokine response; Trypanosoma cruzi

Indexed keywords

GAMMA INTERFERON; HERMES ANTIGEN; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 17; OSTEOPONTIN; VITRONECTIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CD4+ T LYMPHOCYTE; CELL ADHESION; CELL EXPANSION; CELLULAR IMMUNITY; CHAGAS DISEASE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HOST RESISTANCE; IMMUNE RESPONSE; IN VIVO STUDY; MACROPHAGE; MORTALITY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

ANIMALS; BONE MARROW CELLS; CELL ADHESION; CHAGAS DISEASE; DISEASE PROGRESSION; FEMALE; HOST-PARASITE INTERACTIONS; IMMUNITY; INFLAMMATION MEDIATORS; INTERLEUKIN-12; LYMPHOCYTE COUNT; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; OSTEOPONTIN; PARASITEMIA; SPLEEN; SURVIVAL ANALYSIS; TH1 CELLS; TH17 CELLS; TRYPANOSOMA CRUZI;

MURINAE; MUS; TRYPANOSOMA CRUZI;

EID: 84873197732     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.10.027     Document Type: Article

References (44)

1. Rassi A., Rassi A., Marin-Neto J.A. Chagas disease. Lancet 2010, 375:1388-1402.
2. Junqueira C., Caetano B., Bartholomeu D.C., Melo M.B., Ropert C., Rodrigues M.M., et al. The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease. Expert Rev Mol Med 2010, 12:e29.
3. Dutra W.O., Gollob K.J. Current concepts in immunoregulation and pathology of human Chagas disease. Curr Opin Infect Dis 2008, 21:287-292.
4. Savino W., Villa-Verde D.M., Mendes-da-Cruz D.A., Silva-Monteiro E., Perez A.R., Aoki Mdel P., et al. Cytokines and cell adhesion receptors in the regulation of immunity to Trypanosoma cruzi. Cytokine Growth Factor Rev 2007, 18:107-124.
5. Saeftel M., Fleischer B., Hoerauf A. Stage-dependent role of nitric oxide in control of Trypanosoma cruzi infection. Infect Immun 2001, 69:2252-2259.
6. Miyazaki Y., Hamano S., Wang S., Shimanoe Y., Iwakura Y., Yoshida H. IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infection. J Immunol 2010, 185:1150-1157.
7. Gaffen S.L. An overview of IL-17 function and signaling. Cytokine 2008, 43:402-407.
8. Pappu R., Ramirez-Carrozzi V., Sambandam A. The interleukin-17 cytokine family: critical players in host defence and inflammatory diseases. Immunology 2011, 134:8-16.
9. Mazzali M., Kipari T., Ophascharoensuk V., Wesson J.A., Johnson R., Hughes J. Osteopontin - a molecule for all seasons. QJM 2002, 95:3-13.
10. Denhardt T., Guo X. Osteopontin: a protein with diverse functions. FASEB J 1993, 7:1475-1482.
11. Wang K.X., Denhardt D.T. Osteopontin: role in immune regulation and stress responses. Cytokine Growth Factor Rev 2008, 19:333-345.
12. Cantor H., Shinohara M.L. Regulation of T-helper-cell lineage development by osteopontin: the inside story. Nat Rev Immunol 2009, 9:137-141.
13. Ashkar S., Weber G.F., Panoutsakopoulou V., Sanchirico M.E., Jansson M., Zawaideh S., et al. Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science 2000, 287:860-864.
14. Shinohara M.L., Kim J.H., Garcia V.A., Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity 2008, 29:68-78.
15. Shinohara M.L., Lu L., Bu J., Werneck M.B., Kobayashi K.S., Glimcher L.H., et al. Osteopontin expression is essential for interferon-α production by plasmacytoid dendritic cells. Nat Immunol 2006, 7:498-506.
16. Nau G.J., Liaw L., Chupp G.L., Berman J.S., Hogan B.L., Young R.A. Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin. Infect Immun 1999, 67:4223-4230.
17. Maeno Y., Nakazawa S., Dao L.D., Van Tuan N., Giang N.D., Van Hanh T., et al. Osteopontin is involved in Th1-mediated immunity against Plasmodium falciparum infection in a holoendemic malaria region in Vietnam. Acta Trop 2006, 98:305-310.
18. Uede T. Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases. Pathol Int 2011, 61:265-280.
19. + cytotoxic T cells after infection with Trypanosoma cruzi in naive or vaccinated mice. Infect Immun 2006, 74:2477-2481.
20. Corral R.S., Petray P.B. CpG DNA as a Th1-promoting adjuvant in immunization against Trypanosoma cruzi. Vaccine 2000, 19:234-242.
21. Kiefer F.W., Zeyda M., Gollinger K., Pfau B., Neuhofer A., Weichhart T., et al. Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance. Diabetes 2010, 59:935-946.
22. Stout R.D., Jiang C., Matta B., Tietzel I., Watkins S.K., Suttles J. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol 2005, 175:342-349.
23. Gupta S., Garg N.J. Prophylactic efficacy of TcVac2 against Trypanosoma cruzi in mice. PloS Negl Trop Dis 2010, 4:e797.
24. Cribbs D.H., Ghochikyan A., Vasilevko V., Tran M., Petrushina I., Sadzikava N., et al. Adjuvant-dependent modulation of Th1 and Th2 responses to immunization with β-amyloid. Int Immunol 2003, 15:505-514.
25. Murry C.E., Giacheli C.M., Schwartz S.M., Vracko R. Macrophages express osteopontin during repair of myocardial necrosis. Am J Pathol 1994, 145:1450-1462.
26. Zhao W., Wang L., Zhang L., Yuan C., Kuo P.C., Gao C. Differential expression of intracellular and secreted osteopontin isoforms by murine macrophages in response to toll-like receptor agonists. J Biol Chem 2010, 285:20452-20461.
27. Aliberti J.C., Cardoso M.A., Martins G.A., Gazzinelli R.T., Vieira L.Q., Silva J.S. Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes. Infect Immun 1996, 64:1961-1967.
28. + T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. J Immunol 1991, 147:2713-2716.
29. Kollmann T.R., Reikie B., Blimkie D., Way S.S., Hajjar A.M., Arispe K., et al. Induction of protective immunity to Listeria monocytogenes in neonates. J Immunol 2007, 178:3695-3701.
30. Lund S.A., Giachelli C.M., Scatena M. The role of osteopontin in inflammatory processes. J Cell Commun Signal 2009, 3:311-322.
31. Weber G.F., Zawaideh S., Hikita S., Kumar V.A., Cantor H., Ashkar S. Phosphorylation-dependent interaction of osteopontin with its receptors regulates macrophage migration and activation. J Leukoc Biol 2002, 72:752-761.
32. O'Regan A.W., Hayden J.M., Berman J.S. Osteopontin augments CD3-mediated interferon-γ and CD40 ligand expression by T cells, which results in IL-12 production from peripheral blood mononuclear cells. J Leukoc Biol 2000, 68:495-502.
33. + T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis. J Immunol 2008, 181:7480-7488.
34. Craig-Mylius K., Weber G.F., Coburn J., Glickstein L. Borrelia burgdorferi, an extracellular pathogen, circumvents osteopontin in inducing an inflammatory cytokine response. J Leukoc Biol 2005, 77:710-718.
35. Campos M.A., Closel M., Valente E.P., Cardoso J.E., Akira S., Alvarez-Leite J.I., et al. Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88. J Immunol 2004, 172:1711-1718.
36. Ragno S., Romano M., Howell S., Pappin D.J., Jenner P.J., Colston M.J. Changes in gene expression in macrophages infected with Mycobacterium tuberculosis: a combined transcriptomic and proteomic approach. Immunology 2001, 104:99-108.
37. Hertel P.M., Crawford S.E., Finegold M.J., Estes M.K. Osteopontin upregulation in rotavirus-induced murine biliary atresia requires replicating virus but is not necessary for development of biliary atresia. Virology 2011, 417:281-292.
38. Li X., O'Regan A.W., Berman J.S. IFN-γ induction of osteopontin expression in human monocytoid cells. J Interferon Cytokine Res 2003, 23:259-265.
39. Chen G., Zhang X., Li R., Fang L., Niu X., Zheng Y., et al. Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis. Arthritis Rheum 2010, 62:2900-2908.
40. Graefe S.E., Jacobs T., Gaworski I., Klauenberg U., Steeg C., Fleischer B. Interleukin-12 but not interleukin-18 is required for immunity to Trypanosoma cruzi in mice. Microbe Infect 2003, 5:833-839.
41. Vultaggio A., Nencini F., Pratesi S., Maggi L., Guarna A., Annunziato F., et al. The TLR7 ligand 9-benzyl-2-butoxy-8-hydroxy adenine inhibits IL-17 response by eliciting IL-10 and IL-10-inducing cytokines. J Immunol 2011, 186:4707-4715.
42. Mou Z., Jia P., Kuriakose S., Khadem F., Uzonna J.E. Interleukin-17-mediated control of parasitemia in experimental Trypanosoma congolense infection in mice. Infect Immun 2010, 78:5271-5279.
43. Abel L.C., Rizzo L.V., Ianni B., Albuquerque F., Bacal F., Carrara D., et al. Chronic Chagas' disease cardiomyopathy patients display an increased IFN-gamma response to Trypanosoma cruzi infection. J Autoimmun 2001, 17:99-107.
44. da Matta Guedes P.M., Gutierrez F.R., Maia F.L., Milanezi C.M., Silva G.K., Pavanelli W.R., et al. IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating parasite-induced myocarditis. PLoS Negl Trop Dis 2010, 4:e604.