Effect of Bisphenol-A on insulin signal transduction and glucose oxidation in liver of adult male albino rat

Environmental Toxicology and Pharmacology

Volumn 35, Issue 2, 2013, Pages 300-310

  Jayashree, Shankar ^a   Indumathi, Dhananjayan ^a   Akilavalli, Narasimhan ^a   Sathish, Sampath ^a   Selvaraj, Jayaraman ^a   Balasubramanian, Karundevi ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Bisphenol A; Endocrine disruptor; Hyperinsulinemia; Insulin resistance; Xenoestrogen

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; GLUCOSE; GLUCOSE TRANSPORTER 2; INSULIN; MESSENGER RNA; PROTEIN KINASE B; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE OXIDATION; GLYCOGEN ANALYSIS; INSULIN BLOOD LEVEL; LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TESTOSTERONE BLOOD LEVEL; TOXICITY TESTING;

ANIMALS; BENZHYDRYL COMPOUNDS; BLOOD GLUCOSE; CELL MEMBRANE; CYTOSOL; ENDOCRINE DISRUPTORS; GLUCOSE; GLUCOSE TRANSPORTER TYPE 2; GLYCOGEN; INSULIN; LIVER; MALE; OXIDATION-REDUCTION; PHENOLS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; TESTOSTERONE;

EID: 84873174019     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2012.12.016     Document Type: Article

References (54)

1. 2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans. Environ. Health Perspect. 2005, 113:969-977.
2. Alonso-Magdalena P., Morimoto S., Ripoll C., Fuentes E., Nadal A. The estrogenic effect of bisphenol A disrupts pancreatic beta-cell function in vivo and induces insulin resistance. Environ. Health Perspect. 2006, 114:106-112.
3. Alonso-Magdalena P., Ropero A.B., Carrera M.P., Cederroth C.R., Baquie M., Gauthier B.R., Nef S., Stefani E., Nadal A. Pancreatic insulin content regulation by the estrogen receptor ERα. PLoS One 2008, 3:e2069.
4. Alonso-Magdalena P., Morimoto S., Ripoll C., Fuentes E., Nadal A. Bisphenol A exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring. Environ. Health Perspect. 2010, 118:1243-1250.
5. Andersen H.R., Andersson A.M., Arnold S.F., Autrup H., Barfoed M., Beresford N.A., Bjerregaard P., Christiansen L.B., Gissel B., Hummel R., Jørgensen E.B., Korsgaard B., Le Guevel R., Leffers H., McLachlan J., Møller A., Nielsen J.B., Olea N., Oles-Karasko A., Pakdel F., Pedersen K., Perez P., Skakkeboek N.E., Sonnenschein C., Soto A.M., Sumpter J.P., Thorpe S.M., Grandjean P. Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals. Environ. Health Perspect. 1999, 107:89-108.
6. Apelberg B.J., Witter F.R., Herbstman J.B., Calafat A.M., Halden R.U., Needham L.L., Goldman L.R. Cord serum concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in relation to weight and size at birth. Environ. Health Perspect. 2007, 115:1670-1676.
7. Batista T.M., Alonso-Magdalena P., Vieira E., Amaral M.E., Cederroth C.R., Nef S., Quesada I., Carneiro E.M., Nadal A. Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice. PLoS One 2012, 7:e33814.
8. Ben-Jonathan N., Hugo E.R., Brandebourg T.D. Effects of bisphenol A on adipokine release from human adipose tissue: implications for the metabolic syndrome. Mol. Cell. Endocrinol. 2009, 304:49-54.
9. Calafat A.M., Kuklenyik Z., Reidy J.A., Caudill S.P., Ekong J., Needham L.L. Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population. Environ. Health Perspect. 2005, 113:391-395.
10. Calafat A.M., Ye X., Wong L.Y., Reidy J.A., Needham L.L. Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004. Environ. Health Perspect. 2008, 116:39-44.
11. Can A., Semiz O., Cinar O. Bisphenol-A induces cell cycle delay and alters centrosome and spindle microtubular organization in oocytes during meiosis. Mol. Hum. Reprod. 2005, 11:389-396.
12. Casals-Casas C., Feige J.N., Desvergne B. Endocrine disruptors: from endocrine to metabolic disruption. Annu. Rev. Physiol. 2011, 73:135-162.
13. Di Guglielmo G.M., Drake P.G., Baass P.C., Authier F., Posner B.I., Bergeron J.M. Insulin receptor internalization and signaling. Mol. Cell. Biochem. 1998, 182:59-63.
14. Del Prato S., Leonetti F., Simonson D.C., Sheehan P., Matsuda M., DeFronzo R.A. Effect of sustained physiologic hyperinsulinemia and hyperglycemia on insulin secretion and insulin sensitivity in man. Diabetologia 1994, 37:1025-1035.
15. Dodds E.C. The pharmacological action and clinical use of drugs with a camphor- and coramine like action. Proc. R Soc. Med. 1936, 29:655-657.
16. Dombrowski L., Roy D., Marcotte B., Marette A. A new procedure for the isolation of plasma membranes, T tubules and internal membranes from skeletal muscle. Am. J. Physiol. 1996, 270(4 pt 1):E667-E676.
17. Fourney R.M., Miyakoshi J., Day R.S., Randall R.J. Northern blotting: efficient RNA staining and transfer. Focus 1951, 10:5-7.
18. Greenberg C.C., Jurczak M.J., Danos A.M., Brady M.J. Glycogen branches out: new perspectives on the role of glycogen metabolism in the integration of metabolic pathways. Am. J. Physiol. Endocrinol. Metab. 2006, 291:E1-E8.
19. Gribble F.M., Ashcroft F.M. Sulfonylurea sensitivity of adenosine triphosphate-sensitive potassium channels from beta cells and extra pancreatic tissues. Metabolism 2000, 49:3-6.
20. Hassid W.Z., Abraham S. Determination of glycogen with anthrone reagent. Methods Enzymol. 1951, 3:34-37.
21. Jerrold M., Saltiel A.R. PPARg and the treatment of insulin resistance. Trends Endocrinol. Metab. 2000, 11:362-369.
22. Jhala U.S., Canettieri G., Screaton R.A., Kulkarni R.N., Krajewski S., Reed J., Walker J., Lin X., White M., Montminy M. cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes Dev. 2003, 17:1575-1580.
23. 14C metabolism by mouse, rat and rabbit tissues. Comp. Biochem. Physiol. A 1971, 39:599-604.
24. Kahn C.R. Banting lecture. Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes 1994, 43:1066-1084.
25. Kang J., Katayama Y., Kondo F. Biodegradation or metabolism of bisphenol A: from microorganisms to mammals. Toxicology 2006, 217:81-90.
26. Kawai K., Nozaki T., Nishikata H., Aou S., Takii M., Kubo C. Aggressive behavior and serum testosterone concentration during the maturation process of male mice: the effects of fetal exposure to bisphenol A. Environ. Health Perspect. 2003, 111:175-178.
27. Kidani T., Kamei S., Miyawaki J., Aizawa J., Sakayama K., Masuno H. Bisphenol a down regulates Akt signaling and inhibits adiponectin production and secretion in 3T3-L1 adipocytes. J. Atheroscler. Thromb. 2010, 17:834-843.
28. Kim H.I., Kim J.W., Kim S.H., Cha J.Y., Kim K.S., Ahn Y.H. Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter. Diabetes 2000, 49:1517-1524.
29. Kraft L.A., Johnson A.D. Epididymal carbohydrate metabolism-ii, substrates and pathway utilization of caput and cauda epididymal tissue from the rabbit, rat and mouse. Comp. Biochem. Physiol. B: Biochem. Mol. Biol. 1972, 42:451-461.
30. Kwintkiewicz J., Nishi Y., Yanase T., Giudice L.C. Peroxisome proliferator-activated receptor-γ mediates bisphenol a inhibition of fsh-stimulated IGF-1, aromatase, and estradiol in human granulosa cells. Environ. Health Perspect. 2010, 118:400-406.
31. Lammeli U.K. Cleavage of Structural protein during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
32. Lang I.A., Galloway T.S., Scarlett A., Henley W.E., Depledge M., Wallace R.B., Melzer D. Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults. J. Am. Med. Assoc. 2008, 300:1303-1310.
33. Lenie S., Cortvrindt R., Eichenlaub-Ritter U., Smitz J. Continuous exposure to bisphenol A during in vitro follicular development induces meiotic abnormalities. Mutat. Res. 2008, 651:71-81.
34. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 1951, 193:265-275.
35. Mamula P.W., McDonald A.R., Brunetti A., Okabayashi Y., Wong K.Y., Maddux B.A., Logsdon C., Goldfine I.D. Regulating insulin-receptor-gene expression by differentiation and hormones. Diabetes Care 1990, 13:288-301.
36. Nadal A., Rovira J.M., Laribi O. Rapid insulinotropic effect of 17beta-estradiol via a plasma membrane receptor. Faseb J. 1998, 12:1341-1348.
37. Nadal A., Quesada I., Soria B. Homologous and heterologous asynchronicity between identified alpha-, beta- and delta-cells within intact islets of Langerhans in the mouse. J. Physiol. 1999, 517:85-93.
38. Nadal A., Ropero A.B., Laribi O., Maillet M., Fuentes E., Soria B. Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor alpha and estrogen receptor beta. Proc. Natl. Acad. Sci. 2000, 97:11603-11608.
39. Nakamura D., Yanagiba Y., Duan Z., Ito Y., Okamura A., Asaeda N., Tagawa Y., Li C., Taya K., Zhang S.Y., Naito H., Ramdhan D.H., Kamijima M., Nakajima T. Bisphenol A may cause testosterone reduction by adversely affecting both testis and pituitary systems similar to estradiol. Toxicol. Lett. 2010, 194:16-25.
40. Postic C., Dentin R., Girard J. Role of the liver in the control of carbohydrate and lipid homeostasis. Diabetes. Metab. 2004, 30:398-408.
41. Quesada I., Fuentes E., Viso-León M.C., Soria B., Ripoll C., Nadal A. Low doses of the endocrine disruptor bisphenol-A and the native hormone 17beta-estradiol rapidly activate transcription factor CREB. Faseb J. 2002, 16:1671-1673.
42. Rencurel F., Waeber G., Antoine B., Rocchiccioli F., Maulard P., Girard J., Leturque A. Requirement of glucose metabolism for regulation of glucose transporter type 2 (GLUT2) gene expression in liver. Biochem. J. 1996, 314:903-909.
43. Saini V. Molecular mechanisms of insulin resistance in type 2 diabetes mellitus. World J. Diabetes 2010, 15:68-75.
44. Saltiel A.R. New perspectives into the molecular pathogenesis and treatment of type-2 diabetes. Cell 2001, 104:517-529.
45. Smith M.R., Lee H., Nathan D.M. Insulin sensitivity during combined androgen blockade for prostate cancer. J. Clin. Endocrinol. Metab. 2006, 91:1305-1308.
46. Tabb M., Blumberg B. New modes of action for endocrine-disrupting chemicals. Mol. Endocrinol. 2006, 20:475-482.
47. Takao T., Nanamiya W., Nagano I., Asaba K., Kawabata K., Hashimoto K. Exposure with the environmental estrogen bisphenol a disrupts the male reproductive tract in young mice. Life Sci. 1999, 65:2351-2357.
48. Takayanagi S., Tokunaga T., Liu X., Okada H., Matsushima A., Shimohigashi Y. Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERR gamma) with high constitutive activity. Toxicol Lett. 2006, 167:95-105.
49. Takeuchi T., Tsutsumi O. Serum bisphenol A concentrations showed gender differences, possibly linked to androgen levels. Biochem. Biophys. Res. Commun. 2002, 291:76-78.
50. U.S., Environmental Protection Agency Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) 2000, U.S. EPA, Washington, DC.
51. Vandenberg L.N., Hauser R., Marcus M., Olea N., Welshons W.V. Human exposure to bisphenol A (BPA). Reprod. Toxicol. 2007, 24:116-127.
52. Vom Saal F.S., Hughes C. An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. Environ. Health Perspect. 2005, 113:926-932.
53. Wyatt, Brantley Nelson., 2011. The effects of bisphenol A on adipose tissue development, metabolism, and endocrine function and the role it may play in the development of obesity. Master's Thesis, University of Tennessee, 2011.
54. Welshons W.V., Nagel S.C., vom Saal F.S. Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure. Endocrinology 2006, 147:S56-S69.