-
1
-
-
0033063736
-
Cyclooxygenase-2 expression in hepatocellular carcinoma
-
Shiota G, Okubo M, Noumi T, Noguchi N, Oyama K, Takano Y, et al. Cyclooxygenase-2 expression in hepatocellular carcinoma. Hepatogastroenterology 1999; 46:407-412
-
(1999)
Hepatogastroenterology
, vol.46
, pp. 407-412
-
-
Shiota, G.1
Okubo, M.2
Noumi, T.3
Noguchi, N.4
Oyama, K.5
Takano, Y.6
-
2
-
-
0032978469
-
Expression of cyclooxygenase-2 in human hepatocellular carcinoma: Relevance to tumor dedifferentiation
-
Koga H, Sakisaka S, Ohishi M, Kawaguchi T, Taniguchi E, Sasatomi K, et al. Expression of cyclooxygenase-2 in human hepatocellular carcinoma: Relevance to tumor dedifferentiation. Hepatology 1999; 29:688-696
-
(1999)
Hepatology
, vol.29
, pp. 688-696
-
-
Koga, H.1
Sakisaka, S.2
Ohishi, M.3
Kawaguchi, T.4
Taniguchi, E.5
Sasatomi, K.6
-
3
-
-
0034905269
-
Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398
-
Bae SH, Jung ES, Park YM, Kim BS, Kim BK, Kim DG, et al. Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398. Clin Cancer Res 2001; 7:1410-1418
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1410-1418
-
-
Bae, S.H.1
Jung, E.S.2
Park, Y.M.3
Kim, B.S.4
Kim, B.K.5
Kim, D.G.6
-
4
-
-
0041822007
-
Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: Evidence for Akt inhibition in celecoxib-Induced apoptosis
-
Leng J, Han C, Demetris AJ, Michalopoulos GK, Wu T. Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: Evidence for Akt inhibition in celecoxib-Induced apoptosis. Hepatology 2003; 38:756-768
-
(2003)
Hepatology
, vol.38
, pp. 756-768
-
-
Leng, J.1
Han, C.2
Demetris, A.J.3
Michalopoulos, G.K.4
Wu, T.5
-
5
-
-
1842852639
-
Cyclooxygenase-2 pathway correlates with vascular endothelial growth factor expression and tumor angiogenesis in hepatitis B virus-Associated hepatocellular carcinoma
-
Cheng AS, Chan HL, To KF, Leung WK, Chan KK, Liew CT, et al. Cyclooxygenase-2 pathway correlates with vascular endothelial growth factor expression and tumor angiogenesis in hepatitis B virus-Associated hepatocellular carcinoma. Int J Oncol 2004; 24:853-860
-
(2004)
Int J Oncol
, vol.24
, pp. 853-860
-
-
Cheng, A.S.1
Chan, H.L.2
To, K.F.3
Leung, W.K.4
Chan, K.K.5
Liew, C.T.6
-
6
-
-
17844404832
-
Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells
-
Mayoral R, Fernandez-Martinez A, Bosca L, Martin-Sanz P. Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells. Carcinogenesis 2005; 26:753-761
-
(2005)
Carcinogenesis
, vol.26
, pp. 753-761
-
-
Mayoral, R.1
Fernandez-Martinez, A.2
Bosca, L.3
Martin-Sanz, P.4
-
7
-
-
79955478443
-
The soluble EP2 receptor FuEP2/Ex2 suppresses endometrial cancer cell growth in an orthotopic xenograft model in nude mice
-
Takahashi T, Ogawa H, Izumi K, Uehara H. The soluble EP2 receptor FuEP2/Ex2 suppresses endometrial cancer cell growth in an orthotopic xenograft model in nude mice. Cancer Lett 2011; 306:67-75
-
(2011)
Cancer Lett
, vol.306
, pp. 67-75
-
-
Takahashi, T.1
Ogawa, H.2
Izumi, K.3
Uehara, H.4
-
8
-
-
35148889322
-
Prostaglandin receptor EP2 is responsible for cyclooxygenase-2 induction by prostaglandin E2 in mouse skin
-
Ansari KM, Sung YM, He G, Fischer SM. Prostaglandin receptor EP2 is responsible for cyclooxygenase-2 induction by prostaglandin E2 in mouse skin. Carcinogenesis 2007; 28:2063-2068
-
(2007)
Carcinogenesis
, vol.28
, pp. 2063-2068
-
-
Ansari, K.M.1
Sung, Y.M.2
He, G.3
Fischer, S.M.4
-
9
-
-
84856012333
-
Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma
-
Rasmuson A, Kock A, Fuskevag OM, Kruspig B, Simon-Santamaria J, Gogvadze V, et al. Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma. PLoS One 2012; 7:e29331
-
(2012)
PLoS One
, vol.7
-
-
Rasmuson, A.1
Kock, A.2
Fuskevag, O.M.3
Kruspig, B.4
Simon-Santamaria, J.5
Gogvadze, V.6
-
10
-
-
59449084521
-
Prognostic role of PGE2 receptor EP2 in esophageal squamous cell carcinoma
-
Kuo KT, Wang HW, Chou TY, Hsu WH, Hsu HS, Lin CH, et al. Prognostic role of PGE2 receptor EP2 in esophageal squamous cell carcinoma. Ann Surg Oncol 2009; 16:352-360
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 352-360
-
-
Kuo, K.T.1
Wang, H.W.2
Chou, T.Y.3
Hsu, W.H.4
Hsu, H.S.5
Lin, C.H.6
-
11
-
-
70350708152
-
Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-Dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells
-
Yu L, Wu WK, Li ZJ, Li HT, Wu YC, Cho CH. Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-Dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells. Int J Cancer 2009; 125: 2540-2546
-
(2009)
Int J Cancer
, vol.125
, pp. 2540-2546
-
-
Yu, L.1
Wu, W.K.2
Li, Z.J.3
Li, H.T.4
Wu, Y.C.5
Cho, C.H.6
-
12
-
-
73549118352
-
Prostaglandin EP2 receptor expression is increased in Barrett's oesophagus and oesophageal adenocarcinoma
-
Jime'nez P, Piazuelo E, Cebrian C, Ortego J, Strunk M, Garci'a-Gonzalez MA, et al. Prostaglandin EP2 receptor expression is increased in Barrett's oesophagus and oesophageal adenocarcinoma. Aliment Pharmacol Ther 2010; 31:440-451
-
(2010)
Aliment Pharmacol Ther
, vol.31
, pp. 440-451
-
-
Jime'nez, P.1
Piazuelo, E.2
Cebrian, C.3
Ortego, J.4
Strunk, M.5
Garci'a-Gonzalez, M.A.6
-
13
-
-
37349013594
-
Differential expression of E-prostanoid receptors in human hepatocellular carcinoma
-
Breinig M, Rieker R, Eiteneuer E, Wertenbruch T, Haugg AM, Helmke BM, et al. Differential expression of E-prostanoid receptors in human hepatocellular carcinoma. Int J Cancer 2008; 122:547-557
-
(2008)
Int J Cancer
, vol.122
, pp. 547-557
-
-
Breinig, M.1
Rieker, R.2
Eiteneuer, E.3
Wertenbruch, T.4
Haugg, A.M.5
Helmke, B.M.6
-
14
-
-
38149096108
-
Antiproliferative activity of paeoniflorin is through cell cycle arrest and the Fas/Fas ligand-mediated apoptotic pathway in human non-small cell lung cancer A549 cells
-
Hung JY, Yang CJ, Tsai YM, Huang HW, Huang MS. Antiproliferative activity of paeoniflorin is through cell cycle arrest and the Fas/Fas ligand-mediated apoptotic pathway in human non-small cell lung cancer A549 cells. Clin Exp Pharmacol Physiol 2008; 35:141-147
-
(2008)
Clin Exp Pharmacol Physiol
, vol.35
, pp. 141-147
-
-
Hung, J.Y.1
Yang, C.J.2
Tsai, Y.M.3
Huang, H.W.4
Huang, M.S.5
-
15
-
-
54049146611
-
Paeoniflorin suppress NF-kappaB activation through modulation of I kappaB alpha and enhances 5-fluorouracil-Induced apoptosis in human gastric carcinoma cells
-
Wu H, Li W, Wang T, Shu Y, Liu P. Paeoniflorin suppress NF-kappaB activation through modulation of I kappaB alpha and enhances 5-fluorouracil-Induced apoptosis in human gastric carcinoma cells. Biomed Pharmacother 2008; 62:659-666
-
(2008)
Biomed Pharmacother
, vol.62
, pp. 659-666
-
-
Wu, H.1
Li, W.2
Wang, T.3
Shu, Y.4
Liu, P.5
-
16
-
-
80053345315
-
Modulating Bcl-2 family proteins and caspase-3 in induction of apoptosis by paeoniflorin in human cervical cancer cells
-
Zhang L, Zhang S. Modulating Bcl-2 family proteins and caspase-3 in induction of apoptosis by paeoniflorin in human cervical cancer cells. Phytother Res 2011; 25:1551-1557
-
(2011)
Phytother Res
, vol.25
, pp. 1551-1557
-
-
Zhang, L.1
Zhang, S.2
-
17
-
-
84862942390
-
Paeoniflorin modulates multidrug resistance of a human gastric cancer cell line via the inhibition of NF-kappaB activation
-
Fang S, Zhu W, Zhang Y, Shu Y, Liu P. Paeoniflorin modulates multidrug resistance of a human gastric cancer cell line via the inhibition of NF-kappaB activation. Mol Med Report 2012; 5:351-356
-
(2012)
Mol Med Report
, vol.5
, pp. 351-356
-
-
Fang, S.1
Zhu, W.2
Zhang, Y.3
Shu, Y.4
Liu, P.5
-
18
-
-
33645022034
-
Protective effect of paeoniflorin on immunological liver injury induced by bacillus Calmette-Guerin plus lipopolysaccharide: Modulation of tumour necrosis factor-Alpha and interleukin-6 MRNA
-
Liu DF,Wei W, Song LH. Protective effect of paeoniflorin on immunological liver injury induced by bacillus Calmette-Guerin plus lipopolysaccharide: Modulation of tumour necrosis factor-Alpha and interleukin-6 MRNA. Clin Exp Pharmacol Physiol 2006; 33:332-339
-
(2006)
Clin Exp Pharmacol Physiol
, vol.33
, pp. 332-339
-
-
Liu, D.F.1
Wei, W.2
Song, L.H.3
-
19
-
-
80053073788
-
Paeoniflorin attenuates schistosomiasis japonica-Associated liver fibrosis through inhibiting alternative activation of macrophages
-
Chu D, Du M, Hu X,Wu Q, Shen J. Paeoniflorin attenuates schistosomiasis japonica-Associated liver fibrosis through inhibiting alternative activation of macrophages. Parasitology 2011; 138:1259-1271
-
(2011)
Parasitology
, vol.138
, pp. 1259-1271
-
-
Du Chu, D.M.1
Hu, X.2
Wu, Q.3
Shen, J.4
-
20
-
-
0036788542
-
Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells
-
Kern MA, Schubert D, Sahi D, Schoneweiss MM, Moll I, Haugg AM, et al. Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells. Hepatology 2002; 36:885-894
-
(2002)
Hepatology
, vol.36
, pp. 885-894
-
-
Kern, M.A.1
Schubert, D.2
Sahi, D.3
Schoneweiss, M.M.4
Moll, I.5
Haugg, A.M.6
-
21
-
-
0042198296
-
Inhibited proliferation of cyclooxygenase-2 expressing human hepatoma cells by NS-398, a selective COX-2 inhibitor
-
Hu KQ, Yu CH, Mineyama Y, McCracken JD, Hillebrand DJ, Hasan M. Inhibited proliferation of cyclooxygenase-2 expressing human hepatoma cells by NS-398, a selective COX-2 inhibitor. Int J Oncol 2003; 22: 757-763
-
(2003)
Int J Oncol
, vol.22
, pp. 757-763
-
-
Hu, K.Q.1
Yu, C.H.2
Mineyama, Y.3
McCracken, J.D.4
Hillebrand, D.J.5
Hasan, M.6
-
22
-
-
3242809061
-
Cyclooxygenase-2 inhibitors suppress the growth of human hepatocellular carcinoma implants in nude mice
-
Kern MA, Schoneweiss MM, Sahi D, Bahlo M, Haugg AM, Kasper HU, et al. Cyclooxygenase-2 inhibitors suppress the growth of human hepatocellular carcinoma implants in nude mice. Carcinogenesis 2004; 25: 1193-1199
-
(2004)
Carcinogenesis
, vol.25
, pp. 1193-1199
-
-
Kern, M.A.1
Schoneweiss, M.M.2
Sahi, D.3
Bahlo, M.4
Haugg, A.M.5
Kasper, H.U.6
-
23
-
-
77953289963
-
Preventive effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on DEN-Induced hepatocarcinogenesis in rats
-
Nagahara T, Okano J, Fujise Y, Abe R, Murawaki Y. Preventive effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on DEN-Induced hepatocarcinogenesis in rats. Biomed Pharmacother 2010; 64: 319-326
-
(2010)
Biomed Pharmacother
, vol.64
, pp. 319-326
-
-
Nagahara, T.1
Okano, J.2
Fujise, Y.3
Abe, R.4
Murawaki, Y.5
-
24
-
-
6044274282
-
Coxibs and cardiovascular disease
-
Fitzgerald GA. Coxibs and cardiovascular disease. N Engl J Med 2004; 351:1709-1711
-
(2004)
N Engl J Med
, vol.351
, pp. 1709-1711
-
-
Fitzgerald, G.A.1
-
25
-
-
21744453669
-
Relative thromboembolic risks associated with COX-2 inhibitors
-
Jones SC. Relative thromboembolic risks associated with COX-2 inhibitors. Ann Pharmacother 2005; 39:1249-1259
-
(2005)
Ann Pharmacother
, vol.39
, pp. 1249-1259
-
-
Jones, S.C.1
-
26
-
-
63149124347
-
Celecoxib exacerbates hepatic fibrosis and induces hepatocellular necrosis in rats treated with porcine serum
-
Liu H, Wei W, Li X. Celecoxib exacerbates hepatic fibrosis and induces hepatocellular necrosis in rats treated with porcine serum. Prostaglandins Other Lipid Mediat 2009; 88:63-67
-
(2009)
Prostaglandins Other Lipid Mediat
, vol.88
, pp. 63-67
-
-
Liu, H.1
Wei, W.2
Li, X.3
-
27
-
-
61649112686
-
Prostaglandin E2 receptors and COX enzymes in human hepatocellular carcinoma: Role in the regulation of cell growth
-
Cusimano A, Fodera D, Lampiasi N, Azzolina A, Notarbartolo M, Giannitrapani L, et al. Prostaglandin E2 receptors and COX enzymes in human hepatocellular carcinoma: Role in the regulation of cell growth. Ann NY Acad Sci 2009; 1155:300-308
-
(2009)
Ann NY Acad Sci
, vol.1155
, pp. 300-308
-
-
Cusimano, A.1
Fodera, D.2
Lampiasi, N.3
Azzolina, A.4
Notarbartolo, M.5
Giannitrapani, L.6
-
28
-
-
28544444039
-
Prostaglandin E2 promotes colon cancer cell growth through a Gs-Axinbeta-catenin signaling axis
-
Castellone MD, Teramoto H, Williams BO, Druey KM, Gutkind JS. Prostaglandin E2 promotes colon cancer cell growth through a Gs-Axinbeta-catenin signaling axis. Science 2005; 310:1504-1510
-
(2005)
Science
, vol.310
, pp. 1504-1510
-
-
Castellone, M.D.1
Teramoto, H.2
Williams, B.O.3
Druey, K.M.4
Gutkind, J.S.5
-
29
-
-
67749099442
-
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1/2, AKT, NFkappaB, and beta-catenin pathways and activation of intrinsic apoptotic mechanisms
-
Banu SK, Lee J, Speights VJ, Starzinski-Powitz A, Arosh JA. Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1/2, AKT, NFkappaB, and beta-catenin pathways and activation of intrinsic apoptotic mechanisms. Mol Endocrinol 2009; 23:1291-1305
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1291-1305
-
-
Banu, S.K.1
Lee, J.2
Speights, V.J.3
Starzinski-Powitz, A.4
Arosh, J.A.5
-
30
-
-
85047690934
-
Prostaglandin E2 reduces radiation-Induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
-
Tessner TG, Muhale F, Riehl TE, Anant S, Stenson WF. Prostaglandin E2 reduces radiation-Induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation. J Clin Invest 2004; 114:1676-1685
-
(2004)
J Clin Invest
, vol.114
, pp. 1676-1685
-
-
Tessner, T.G.1
Muhale, F.2
Riehl, T.E.3
Anant, S.4
Stenson, W.F.5
-
31
-
-
33745317580
-
Peptidoglycaninduced IL-6 production in RAW 264.7 macrophages is mediated by cyclooxygenase-2, PGE2/PGE4 receptors, protein kinase A, I kappa B kinase, and NF-kappa B
-
Chen BC, Liao CC, Hsu MJ, Liao YT, Lin CC, Sheu JR, et al. Peptidoglycaninduced IL-6 production in RAW 264.7 macrophages is mediated by cyclooxygenase-2, PGE2/PGE4 receptors, protein kinase A, I kappa B kinase, and NF-kappa B. J Immunol 2006; 177:681-693
-
(2006)
J Immunol
, vol.177
, pp. 681-693
-
-
Chen, B.C.1
Liao, C.C.2
Hsu, M.J.3
Liao, Y.T.4
Lin, C.C.5
Sheu, J.R.6
-
32
-
-
33646126051
-
A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins
-
Nishikawa T, Nakajima T, Moriguchi M, Jo M, Sekoguchi S, Ishii M, et al A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins. J Hepatol 2006; 44:1074-1082
-
(2006)
J Hepatol
, vol.44
, pp. 1074-1082
-
-
Nishikawa, T.1
Nakajima, T.2
Moriguchi, M.3
Jo, M.4
Sekoguchi, S.5
Ishii, M.6
-
33
-
-
77955289199
-
Shear-Induced interleukin-6 synthesis in chondrocytes: Roles of E prostanoid (EP) 2 and EP3 in cAMP/protein kinase A- And PI3-K/Akt-Dependent NF-kappaB activation
-
Wang P, Zhu F, Lee NH, Konstantopoulos K. Shear-Induced interleukin-6 synthesis in chondrocytes: Roles of E prostanoid (EP) 2 and EP3 in cAMP/protein kinase A- And PI3-K/Akt-Dependent NF-kappaB activation. J Biol Chem 2010; 285:24793-24804
-
(2010)
J Biol Chem
, vol.285
, pp. 24793-24804
-
-
Wang, P.1
Zhu, F.2
Lee, N.H.3
Konstantopoulos, K.4
-
34
-
-
77952657476
-
Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- And phosphatidylinositol 3-kinase-Dependent NF-kappaB activation
-
Wang P, Zhu F, Konstantopoulos K. Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- And phosphatidylinositol 3-kinase-Dependent NF-kappaB activation. Am J Physiol Cell Physiol 2010; 298:C1445-C1456
-
(2010)
Am J Physiol Cell Physiol
, vol.298
-
-
Wang, P.1
Zhu, F.2
Konstantopoulos, K.3
-
35
-
-
27744579438
-
Involvement of Bcl-2 family, cytochrome C and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cells
-
Lin HI, Lee YJ, Chen BF, Tsai MC, Lu JL, Chou CJ, et al. Involvement of Bcl-2 family, cytochrome C and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cells. Cancer Lett 2005; 230: 248-259
-
(2005)
Cancer Lett
, vol.230
, pp. 248-259
-
-
Lin, H.I.1
Lee, Y.J.2
Chen, B.F.3
Tsai, M.C.4
Lu, J.L.5
Chou, C.J.6
-
36
-
-
84862798464
-
Paeoniflorin inhibits growth of human colorectal carcinoma HT 29 cells in vitro and in vivo
-
Wang H, Zhou H,Wang CX, Li YS, Xie HY, Luo JD, et al. Paeoniflorin inhibits growth of human colorectal carcinoma HT 29 cells in vitro and in vivo. Food Chem Toxicol 2012; 50:1560-1567
-
(2012)
Food Chem Toxicol
, vol.50
, pp. 1560-1567
-
-
Wang, H.1
Zhou, H.2
Wang, C.X.3
Li, Y.S.4
Xie, H.Y.5
Luo, J.D.6
-
37
-
-
84860396038
-
Paeoniflorin inhibits function of synoviocytes pretreated by rIL-1alpha and regulates EP4 receptor expression
-
Chang Y, Zhang L, Wang C, Jia XY, Wei W. Paeoniflorin inhibits function of synoviocytes pretreated by rIL-1alpha and regulates EP4 receptor expression. J Ethnopharmacol 2011; 137:1275-1282
-
(2011)
J Ethnopharmacol
, vol.137
, pp. 1275-1282
-
-
Chang, Y.1
Zhang, L.2
Wang, C.3
Jia, X.Y.4
Wei, W.5
|