Paeoniflorin inhibits function of synoviocytes pretreated by rIL-1α and regulates EP 4 receptor expression

Journal of Ethnopharmacology

Volumn 137, Issue 3, 2011, Pages 1275-1282

  Chang, Yan ^a   Zhang, Lei ^a   Wang, Chun ^a   Jia, Xiao Yi ^a   Wei, Wei ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Collagen induced arthritis; Cyclic adenosine monophosphate; E prostanoid; Paeoniflorin; Synoviocytes

Indexed keywords

CYCLIC AMP; INTERLEUKIN 1; PAEONIFLORIN; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; RECOMBINANT INTERLEUKIN 1ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTHRITIS; ARTICLE; CELL PROLIFERATION; COLLAGEN INDUCED ARTHRITIS; CONTROLLED STUDY; IN VITRO STUDY; INHIBITION KINETICS; MALE; NONHUMAN; PAEONIA LACTIFLORA; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; SPLEEN CELL; SYNOVIOCYTE; THYMOCYTE; TREATMENT RESPONSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; BENZOIC ACIDS; BLOTTING, WESTERN; BRIDGED COMPOUNDS; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN TYPE II; CYCLIC AMP; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSIDES; INTERLEUKIN-1ALPHA; MALE; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; RECOMBINANT PROTEINS; SPLEEN; SYNOVIAL MEMBRANE; THYMOCYTES; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

PAEONIA LACTIFLORA; PAEONIACEAE; RATTUS;

EID: 84860396038     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.07.057     Document Type: Article

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