-
1
-
-
33745517203
-
Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis
-
Kremsdorf D., Soussan P., Paterlini-Brechot P., Brechot C. Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis. Oncogene 2006, 25:3823-3833.
-
(2006)
Oncogene
, vol.25
, pp. 3823-3833
-
-
Kremsdorf, D.1
Soussan, P.2
Paterlini-Brechot, P.3
Brechot, C.4
-
2
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: from genes to environment
-
Farazi P.A., DePinho R.A. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat. Rev. Cancer 2006, 6:674-687.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
3
-
-
79952232216
-
Global cancer statistics, CA
-
Jemal A., Bray F., Center M.M., Ferlay J., Ward E., Forman D. Global cancer statistics, CA. Cancer J. Clin. 2011, 61:69-90.
-
(2011)
Cancer J. Clin.
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
4
-
-
80052411388
-
Hepatitis B virus X gene and hepatocarcinogenesis
-
Ng S.A., Lee C. Hepatitis B virus X gene and hepatocarcinogenesis. J. Gastroenterol. 2011, 46:974-990.
-
(2011)
J. Gastroenterol.
, vol.46
, pp. 974-990
-
-
Ng, S.A.1
Lee, C.2
-
5
-
-
78649630185
-
Hepatitis B virus X protein stimulates IL-6 expression in hepatocytes via a MyD88-dependent pathway
-
Xiang W.Q., Feng W.F., Ke W., Sun Z., Chen Z., Liu W. Hepatitis B virus X protein stimulates IL-6 expression in hepatocytes via a MyD88-dependent pathway. J Hepatol. 2011, 54:26-33.
-
(2011)
J Hepatol.
, vol.54
, pp. 26-33
-
-
Xiang, W.Q.1
Feng, W.F.2
Ke, W.3
Sun, Z.4
Chen, Z.5
Liu, W.6
-
6
-
-
78751472196
-
Hepatitis B x-interacting protein induces HepG2 cell proliferation through activation of the phosphatidylinositol 3-kinase/Akt pathway
-
Wang F.Z., Fei H.R., Lian L.H., Wang J.M., Qiu Y.Y. Hepatitis B x-interacting protein induces HepG2 cell proliferation through activation of the phosphatidylinositol 3-kinase/Akt pathway. Exp. Biol. Med. (Maywood) 2011, 236:62-69.
-
(2011)
Exp. Biol. Med. (Maywood)
, vol.236
, pp. 62-69
-
-
Wang, F.Z.1
Fei, H.R.2
Lian, L.H.3
Wang, J.M.4
Qiu, Y.Y.5
-
7
-
-
0036284086
-
The promoting molecular mechanism of alpha-fetoprotein on the growth of human hepatoma Bel7402 cell line
-
Li M.S., Li P.F., He S.P., Du G.G., Li G. The promoting molecular mechanism of alpha-fetoprotein on the growth of human hepatoma Bel7402 cell line. World J. Gastroenterol. 2002, 8:469-475.
-
(2002)
World J. Gastroenterol.
, vol.8
, pp. 469-475
-
-
Li, M.S.1
Li, P.F.2
He, S.P.3
Du, G.G.4
Li, G.5
-
8
-
-
0036942394
-
Enhancement of proliferation of HeLa cells by the alpha-fetoprotein
-
Li M.S., Li P.F., Li G., Du G.G. Enhancement of proliferation of HeLa cells by the alpha-fetoprotein. Acta Biochim. Biophys. Sin. 2002, 34:769-774.
-
(2002)
Acta Biochim. Biophys. Sin.
, vol.34
, pp. 769-774
-
-
Li, M.S.1
Li, P.F.2
Li, G.3
Du, G.G.4
-
9
-
-
0036595963
-
The intracellular mechanism of alpha-fetoprotein promoting the proliferation of NIH3T3 cells
-
Li M.S., Li P.F., Yang F.Y., He S.P., Du G.G., Li G. The intracellular mechanism of alpha-fetoprotein promoting the proliferation of NIH3T3 cells. Cell Res. 2002, 12:151-156.
-
(2002)
Cell Res.
, vol.12
, pp. 151-156
-
-
Li, M.S.1
Li, P.F.2
Yang, F.Y.3
He, S.P.4
Du, G.G.5
Li, G.6
-
10
-
-
78649883907
-
Alpha-fetoprotein: a new member of intracellular signal molecules in regulation of the PI3K/AKT signaling in human hepatoma cell lines
-
Li M., Li H., Li C., Wang S., Jiang W., Liu Z., Zhou S., Liu X., McNutt M.A., Li G. Alpha-fetoprotein: a new member of intracellular signal molecules in regulation of the PI3K/AKT signaling in human hepatoma cell lines. Int. J. Cancer 2011, 128:524-532.
-
(2011)
Int. J. Cancer
, vol.128
, pp. 524-532
-
-
Li, M.1
Li, H.2
Li, C.3
Wang, S.4
Jiang, W.5
Liu, Z.6
Zhou, S.7
Liu, X.8
McNutt, M.A.9
Li, G.10
-
11
-
-
1942466512
-
Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity
-
Wang G.L., Iakova P., Wilde M., Awad S., Timchenko N.A. Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity. Genes Dev. 2004, 8:912-925.
-
(2004)
Genes Dev.
, vol.8
, pp. 912-925
-
-
Wang, G.L.1
Iakova, P.2
Wilde, M.3
Awad, S.4
Timchenko, N.A.5
-
12
-
-
48649106218
-
PIK3IP1, a negative regulator of PI3K, suppresses the development of hepatocellular carcinoma
-
He X., Zhu Z., Johnson C., Stoops J., Eaker A.E., Bowen W., DeFrances M.C. PIK3IP1, a negative regulator of PI3K, suppresses the development of hepatocellular carcinoma. Cancer Res. 2008, 68:5591-5598.
-
(2008)
Cancer Res.
, vol.68
, pp. 5591-5598
-
-
He, X.1
Zhu, Z.2
Johnson, C.3
Stoops, J.4
Eaker, A.E.5
Bowen, W.6
DeFrances, M.C.7
-
13
-
-
84861567957
-
MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma
-
Fang Y., Xue J.L., Shen Q., Chen J., Tian L. MicroRNA-7 inhibits tumor growth and metastasis by targeting the phosphoinositide 3-kinase/Akt pathway in hepatocellular carcinoma. Hepatology 2012, 55:1852-1862.
-
(2012)
Hepatology
, vol.55
, pp. 1852-1862
-
-
Fang, Y.1
Xue, J.L.2
Shen, Q.3
Chen, J.4
Tian, L.5
-
14
-
-
27644556527
-
Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance
-
Lim K.H., Counter C.M. Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance. Cancer Cell 2005, 8:381-392.
-
(2005)
Cancer Cell
, vol.8
, pp. 381-392
-
-
Lim, K.H.1
Counter, C.M.2
-
15
-
-
79955530689
-
Down-regulation of the tumor suppressor C-terminal Src kinase (Csk)-binding protein (Cbp)/PAG1 is mediated by epigenetic histone modifications via the mitogen-activated protein kinase (MAPK)/Phosphatidylinositol 3-kinase (PI3K) pathway
-
Suzuki K., Oneyama C., Kimura H., Tajima S., Okada M. Down-regulation of the tumor suppressor C-terminal Src kinase (Csk)-binding protein (Cbp)/PAG1 is mediated by epigenetic histone modifications via the mitogen-activated protein kinase (MAPK)/Phosphatidylinositol 3-kinase (PI3K) pathway. J. Biol. Chem. 2011, 286:15698-15706.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 15698-15706
-
-
Suzuki, K.1
Oneyama, C.2
Kimura, H.3
Tajima, S.4
Okada, M.5
-
16
-
-
34250323467
-
CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway
-
Liang Z., Brooks J., Willard M., Liang K., Yoon Y., Kang S., Shim H. CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway. Biochem. Biophys. Res. Commun. 2007, 359:716-722.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.359
, pp. 716-722
-
-
Liang, Z.1
Brooks, J.2
Willard, M.3
Liang, K.4
Yoon, Y.5
Kang, S.6
Shim, H.7
-
17
-
-
84873098449
-
Alpha-fetoprotein up-regulated the expression of c-Src in hepatoma cells is PTEN/AKT signaling pathway dependent or independent[abstract]
-
Li M., Xie X., Fu S., Zhu M., Li G. Alpha-fetoprotein up-regulated the expression of c-Src in hepatoma cells is PTEN/AKT signaling pathway dependent or independent[abstract]. J. Clin. Oncol. 2010, 28:e21061.
-
(2010)
J. Clin. Oncol.
, vol.28
-
-
Li, M.1
Xie, X.2
Fu, S.3
Zhu, M.4
Li, G.5
-
18
-
-
84863989193
-
Alpha-fetoprotein acts as a novel signal molecule and mediates transcription of Fn14 in human hepatocellular carcinoma
-
Wang S., Jiang W., Chen X., Zhang C., Li H., Hou W., Liu Z., McNutt M.A., Lu F., Li G. Alpha-fetoprotein acts as a novel signal molecule and mediates transcription of Fn14 in human hepatocellular carcinoma. J. Hepatol. 2012, 57:322-329.
-
(2012)
J. Hepatol.
, vol.57
, pp. 322-329
-
-
Wang, S.1
Jiang, W.2
Chen, X.3
Zhang, C.4
Li, H.5
Hou, W.6
Liu, Z.7
McNutt, M.A.8
Lu, F.9
Li, G.10
-
19
-
-
65649086739
-
Alpha fetoprotein is a novel protein-binding partner for caspase-3 and blocks the apoptotic signaling pathway in human hepatoma cells
-
Li M., Li H., Li C., Zhou S., Guo L., Liu H., Jiang W., Liu X., Li P., McNutt M.A., Li G. Alpha fetoprotein is a novel protein-binding partner for caspase-3 and blocks the apoptotic signaling pathway in human hepatoma cells. Int. J. Cancer 2009, 124:2845-2854.
-
(2009)
Int. J. Cancer
, vol.124
, pp. 2845-2854
-
-
Li, M.1
Li, H.2
Li, C.3
Zhou, S.4
Guo, L.5
Liu, H.6
Jiang, W.7
Liu, X.8
Li, P.9
McNutt, M.A.10
Li, G.11
-
20
-
-
68749108259
-
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer
-
Wang Y., Zhang H., Chen Y., Sun Y., Yang F., Yu W., Liang J., Sun L., Yang X., Shi L., Li R., Li Y., Zhang Y., Li Q., Yi X., Shang Y. LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell 2009, 138:660-672.
-
(2009)
Cell
, vol.138
, pp. 660-672
-
-
Wang, Y.1
Zhang, H.2
Chen, Y.3
Sun, Y.4
Yang, F.5
Yu, W.6
Liang, J.7
Sun, L.8
Yang, X.9
Shi, L.10
Li, R.11
Li, Y.12
Zhang, Y.13
Li, Q.14
Yi, X.15
Shang, Y.16
-
21
-
-
70349960049
-
G. Li. Cytoplasmic alpha-fetoprotein functions as a co-repressor in RA-RAR signaling to promotethegrowth of human hepatoma Bel7402 cells
-
Li M., Li H., Li C., Guo L., Liu H., Zhou S., Liu X., Chen Z., Shi X., McNutt M.A. G. Li. Cytoplasmic alpha-fetoprotein functions as a co-repressor in RA-RAR signaling to promotethegrowth of human hepatoma Bel7402 cells. Cancer Lett. 2009, 285:190-199.
-
(2009)
Cancer Lett.
, vol.285
, pp. 190-199
-
-
Li, M.1
Li, H.2
Li, C.3
Guo, L.4
Liu, H.5
Zhou, S.6
Liu, X.7
Chen, Z.8
Shi, X.9
McNutt, M.A.10
-
22
-
-
83955161219
-
Impact of intracellular alpha fetoprotein on retinoic acid receptors-mediated expression of GADD153 in human hepatoma cell lines
-
Li C., Wang S., Jiang W., Li H., Liu Z., Zhang C., McNutt M.A., Li G. Impact of intracellular alpha fetoprotein on retinoic acid receptors-mediated expression of GADD153 in human hepatoma cell lines. Int. J. Cancer 2012, 130:754-764.
-
(2012)
Int. J. Cancer
, vol.130
, pp. 754-764
-
-
Li, C.1
Wang, S.2
Jiang, W.3
Li, H.4
Liu, Z.5
Zhang, C.6
McNutt, M.A.7
Li, G.8
-
23
-
-
84255200363
-
Hepatitis B virus large surface antigen promotes liver carcinogenesis by activating the Src/PI3K/Akt pathway
-
Liu H., Xu J., Zhou L., Yun X., Chen L., Wang S., Sun L., Wen Y., Gu J. Hepatitis B virus large surface antigen promotes liver carcinogenesis by activating the Src/PI3K/Akt pathway. Cancer Res. 2011, 71:7547-7557.
-
(2011)
Cancer Res.
, vol.71
, pp. 7547-7557
-
-
Liu, H.1
Xu, J.2
Zhou, L.3
Yun, X.4
Chen, L.5
Wang, S.6
Sun, L.7
Wen, Y.8
Gu, J.9
-
24
-
-
23944489424
-
Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation
-
List K., Szabo R., Molinolo A., Sriuranpong V., Redeye V., Murdock T., Burke B., Nielsen B.S., Gutkind J.S., Bugge T.H. Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation. Genes Dev. 2005, 19:1934-1950.
-
(2005)
Genes Dev.
, vol.19
, pp. 1934-1950
-
-
List, K.1
Szabo, R.2
Molinolo, A.3
Sriuranpong, V.4
Redeye, V.5
Murdock, T.6
Burke, B.7
Nielsen, B.S.8
Gutkind, J.S.9
Bugge, T.H.10
-
25
-
-
75149186207
-
Increased expression of vascular endothelial growth factor-C and nuclear CXCR4 in hepatocellular carcinoma is correlated with lymph node metastasis and poor outcome
-
Xiang Z., Zeng Z., Tang Z., Fan J., Sun H., Wu W., Tan Y. Increased expression of vascular endothelial growth factor-C and nuclear CXCR4 in hepatocellular carcinoma is correlated with lymph node metastasis and poor outcome. Cancer J. 2009, 15:519-525.
-
(2009)
Cancer J.
, vol.15
, pp. 519-525
-
-
Xiang, Z.1
Zeng, Z.2
Tang, Z.3
Fan, J.4
Sun, H.5
Wu, W.6
Tan, Y.7
-
26
-
-
0034623236
-
Hepatitis B viral transactivator HBx alleviates p53-mediated repression of α-fetoprotein gene expression
-
Ogden S.K., Lee K.C., Barton M.C. Hepatitis B viral transactivator HBx alleviates p53-mediated repression of α-fetoprotein gene expression. J. Biol. Chem. 2000, 275:27806-27814.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27806-27814
-
-
Ogden, S.K.1
Lee, K.C.2
Barton, M.C.3
-
27
-
-
33750346771
-
PTEN modulates hepatitis B virus-X protein induced survival signaling in Chang liver cells
-
Kang-Park S., Im J.H., Lee J.H., Lee Y.I. PTEN modulates hepatitis B virus-X protein induced survival signaling in Chang liver cells. Virus Res. 2006, 122:53-60.
-
(2006)
Virus Res.
, vol.122
, pp. 53-60
-
-
Kang-Park, S.1
Im, J.H.2
Lee, J.H.3
Lee, Y.I.4
-
28
-
-
84859156758
-
PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma
-
Dituri F., Mazzocca A., Lupo L., Edling C.E., Azzariti A., Antonaci S., Falasca M., Giannelli G. PI3K class IB controls the cell cycle checkpoint promoting cell proliferation in hepatocellular carcinoma. Int. J. Cancer 2012, 130:2505-2513.
-
(2012)
Int. J. Cancer
, vol.130
, pp. 2505-2513
-
-
Dituri, F.1
Mazzocca, A.2
Lupo, L.3
Edling, C.E.4
Azzariti, A.5
Antonaci, S.6
Falasca, M.7
Giannelli, G.8
-
29
-
-
79953775554
-
Review of the putative cell-surface receptors for alpha-fetoprotein: identification of a candidate receptor protein family
-
Mizejewski G.J. Review of the putative cell-surface receptors for alpha-fetoprotein: identification of a candidate receptor protein family. Tumour Biol. 2011, 32:241-258.
-
(2011)
Tumour Biol.
, vol.32
, pp. 241-258
-
-
Mizejewski, G.J.1
-
30
-
-
80053989452
-
Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-targeting: first in-human results
-
van Dam G.M., Themelis G., Crane L.M.A., Harlaar N.J., Pleijhuis R.G., Kelder W., Sarantopoulos A., de Jong J.S., Arts H.J.G., van der Zee A.G.J., Bart J., Low P.S., Ntziachristos V. Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-targeting: first in-human results. Nat. Med. 2011, 17:1315-1319.
-
(2011)
Nat. Med.
, vol.17
, pp. 1315-1319
-
-
van Dam, G.M.1
Themelis, G.2
Crane, L.M.A.3
Harlaar, N.J.4
Pleijhuis, R.G.5
Kelder, W.6
Sarantopoulos, A.7
de Jong, J.S.8
Arts, H.J.G.9
van der Zee, A.G.J.10
Bart, J.11
Low, P.S.12
Ntziachristos, V.13
-
31
-
-
84155180684
-
Hepatitis B virus X (HBx) induces tumorigenicity of hepatic progenitor cells in 3,5-diethoxycarbonyl-1,4-dihydrocollidine-treated HBx transgenic mice
-
Wang C., Yang W., Yan H.X., Luo T., Zhang J., Tang L., Wu F.Q., Zhang H.L., Yu L.X., Zheng L.Y., Li Y.Q., Dong W., He Y.Q., Liu Q., Zou S.S., Lin Y., Hu L., Li Z., Wu M.C., Wang H.Y. Hepatitis B virus X (HBx) induces tumorigenicity of hepatic progenitor cells in 3,5-diethoxycarbonyl-1,4-dihydrocollidine-treated HBx transgenic mice. Hepatology 2012, 55:108-120.
-
(2012)
Hepatology
, vol.55
, pp. 108-120
-
-
Wang, C.1
Yang, W.2
Yan, H.X.3
Luo, T.4
Zhang, J.5
Tang, L.6
Wu, F.Q.7
Zhang, H.L.8
Yu, L.X.9
Zheng, L.Y.10
Li, Y.Q.11
Dong, W.12
He, Y.Q.13
Liu, Q.14
Zou, S.S.15
Lin, Y.16
Hu, L.17
Li, Z.18
Wu, M.C.19
Wang, H.Y.20
more..
-
32
-
-
84865545940
-
Hepatitis B virus X protein stabilizes AIB1 protein and cooperates with it to promote human hepatocellular carcinoma cell invasiveness
-
Liu Y., Tong Z., Li T., Chen Q., Zhuo L., Li W., Wu R.C., Yu C. Hepatitis B virus X protein stabilizes AIB1 protein and cooperates with it to promote human hepatocellular carcinoma cell invasiveness. Hepatology 2012, 56:1015-1024.
-
(2012)
Hepatology
, vol.56
, pp. 1015-1024
-
-
Liu, Y.1
Tong, Z.2
Li, T.3
Chen, Q.4
Zhuo, L.5
Li, W.6
Wu, R.C.7
Yu, C.8
|