Review of the putative cell-surface receptors for alpha-fetoprotein: Identification of a candidate receptor protein family

Tumor Biology

Volumn 32, Issue 2, 2011, Pages 241-258

  Mizejewski, Gerald J ^a  

^a WADSWORTH CENTER   (United States)

Author keywords

Albumin receptor; Alpha fetoprotein; Cancer cells; Dendritic cells; Pattern recognition; Scavenger receptors; Stromal cells; T cells

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; ALBUMIN; ALBUMIN RECEPTOR; ALPHA FETOPROTEIN; CD36 ANTIGEN; CELL SURFACE RECEPTOR; COLLECTIN; CXCL16 CHEMOKINE; OXIDIZED LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; SCAVENGER RECEPTOR; SCAVENGER RECEPTOR BI; ALPHA FETOPROTEIN RECEPTOR, HUMAN; ALPHA-FETOPROTEIN RECEPTOR, HUMAN; RECEPTOR; TUMOR MARKER;

BIOLOGICAL ACTIVITY; CANCER CELL; ENDOCYTOSIS; ENDOTHELIUM CELL; FOCAL ADHESION; HUMAN; INTRACELLULAR TRANSPORT; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLACENTA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION; STROMA CELL; TUMOR GROWTH; ANIMAL; COMPUTER SIMULATION; DISEASE MODEL; METABOLISM;

ALPHA-FETOPROTEINS; ANIMALS; COMPUTER SIMULATION; DISEASE MODELS, ANIMAL; HUMANS; RECEPTORS, CELL SURFACE; RECEPTORS, PEPTIDE; RECEPTORS, SCAVENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 79953775554     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-010-0134-5     Document Type: Review

References (120)

1. Mizejewski GJ. Alpha-fetoprotein structure and function: relevance to isoforms, epitopes, and conformational variants. Exp Biol Med Maywood. 2001;226:377-408. (Pubitemid 32506364)
2. Mizjewswki G (2009) Mapping on structure-function peptide sites on the human alpha-fetoprotein amino acid sequence. Atlas of Genetics and Cytogenetics in Oncology and Haematology. Deep Insight Section, 1-65.
3. Naidu S, Peterson ML, Spear BT. Alpha-fetoprotein related gene (ARG): a new member of the albumin gene family that is no longer functional in primates. Gene. 2009;449(1-2):95-102.
4. Mizejewski GJ. Physiology of alpha-fetoprotein as a biomarker for perinatal distress: relevance to adverse pregnancy outcome. Exp Biol Med. 2007;232(8):993-1004. (Pubitemid 47358183)
5. Mizejewski GJ. Biological role of AFP in cancer: prospects for anticancer therapy. Expert Rev Anticancer Ther. 2002;2(6):89-115.
6. Li MS, Li PF, He SP, Du GG, Li G. The promoting molecular mechanism of alpha-fetoprotein on the growth of human hepatoma Bel7402 cell line. World J Gastroenterol. 2002;8:469-75. (Pubitemid 34692744)
7. Li MS, Li PF, Yang FY, He SP, Du GG, Li G. The intracellular mechanism of alpha-fetoprotein promoting the proliferation of NIH 3 T3 cells. Cell Res. 2002;12:151-6. (Pubitemid 135708323)
8. Benno RH, Williams TH. Evidence for intracellular localization of AFP in the developing rat brain. Brain Res. 1978;142-6.
9. Moro R, Uriel J. Early localization of AFP in the developing nervous system of the chicken. Onco-develop. Biol Méd. 1981;2:391-9.
10. Uriel J, Trojan J, Dubauch P, Pineira A. Intracellular AFP and albumin in the developing nervous system of the baboon. Pathol Biol. 1982;30:79-84.
11. Toran-Alleran CD. Coexistence of α-fetoprotein, albumin and transferring immunoreactivity in neurons of the developing mouse brain. Nature. 1980;286:733-6.
12. Trojan J, Uriel J. Immunocytochemical localization of AFP and serumalbumin in ecto-, meso-, and endodermal tissue derivatives of the developing rat. Oncodevelop Biol Med. 1982;3:13-22. (Pubitemid 12006508)
13. Poupon UJ, MF GM. Alpha-fetoprotein uptake by cloned cell lines derived from a nickel-induced rat rhabdomysosarcoma. Br J Cancer. 1983;48:261-9.
14. Hajeri-Germond M, Trojan J, Uriel J, Hau JJ. In vitro uptake of exogenous AFP by chicken dorsal root ganglia. Dev Neurosci. 1983;6:11-5.
15. Uriel J, Failly-Crepin C, Villacampa MJ, Pineiro A, Geuskens. Incorporation of AFP by the MCF-7 human breast cancer cell line. Tumor Biol. 1984;5:41-51.
16. Villacampa MJ, Moro R, Naval J, Failly-Crepin C, Lampreave F, Uriel J. Alpha-fetoprotein receptors in a human breast cancer cell line. Biochem Biophys Res Commun. 1984;122:1322-7. (Pubitemid 14073567)
17. Hajere-Germond M, Naval J, Trojan J, Uriel J. The uptake of alpha-fetoprotein by C-1300 mouse neuroblastoma cells. Brit J Cancer. 1985;51:791-7. (Pubitemid 15056992)
18. 3 H-arachidonic acid bound to AFP by autoradiography in rat rhabdomyosarcoma cells. J Cell Physiol. 1986;128:389-96.
19. Laborda J, Naval J, Allouche M, Calvo M, Georgoulias V, Mishal Z, et al. Specific uptake of alpha-fetoprotein by malignant human lymphoid cells. Int J Cancer. 1987;40:314-8. (Pubitemid 17156125)
20. Geuskens M, Torres JM, Esteban C, Uriel J. Morphological characterization of the pathway of endocytosis and intracellular processing of transferrin and alpha-fetoprotein in human T-lymphocytes stimulated with phytohemagglutinin (PHA). Eur J Cell Biol. 1989;418-27. (Pubitemid 20026978)
21. Laborda J, Naval J, Calvo M, Lampreave F, Uriel J. Alpha-fetoprotein and albumin uptake by mouse tissues during development. Biol Neonate. 1989;56:332-41. (Pubitemid 19276504)
22. Torres JM, Geuskens M, Uriel J. Receptor-mediated endocytosis and recycling of alpha-fetoprotein in human β-lymphoma and Tleukemia cells. Int J Cancer. 1991;47:110-7.
23. Esteban C, Geuskens M, Uriel J. Activation of an alphafetoprotein (AFP)/receptor autocrine loop in HT-29 human colon carcinoma cells. Int J Cancer. 1991;49:425-30.
24. Hajeri-Germond M, Trojan J, Uriel J. Alpha-fetoprotein uptake by differentiating neuroretinal structures of the chick embryo. Dev Neurosci. 1991;13:164-70.
25. Geuskens J, Dupressoir T, Uriel J. A study, by electron microscopy, of the specific uptake of alpha-fetoprotein by mouse embryonic fibroblasts in relation to in vitro aging, and my human mammary epithelial tumour cells in comparison with normal donors' cells. J Submicrosc Cytol Pathol. 1991;23:59-66.
26. Esteban C, Trojan J, Macho A, Mishal Z, Lafarge-Frayssinet Ch, Uriel J. Activation of an AFP/receptor pathway in human normal and malignant peripheral blood mononuclear cells. Leukemia. 1993;7:1807-16. (Pubitemid 23347300)
27. Lorenzo HC, Geuskens M, Macho A, et al. Alpha-fetoprotein binding and uptake by primary cultures of human skeletal muscle. Tumor Biol. 1996;17:251-60. (Pubitemid 26227622)
28. Brownbill P, Edwards D, Jones C, Mahendran D, Owen D, Sibley C, et al. Mechanisms of alphafetoprotein transfer in the perfused human placental cotyledon from uncomplicated pregnancy. J Clin Invest. 1995;96:2220-6.
29. Posypanova GA, Gorokhovets NV, Makarov VA, Savvateeva LV, Kireeva NN, Severin SE, et al. Recombinant alpha-fetoprotein C-terminal fragment: the new recombinant vector for targeted delivery. J Drug Target. 2008;16:321-8. (Pubitemid 351637411)
30. Uriel J, Trojan J, Moro R, Pineiro A. Intracellular uptake of alpha-fetoprotein: a marker of neural differentiation. Ann NY Acad Sci. 1983;417:321-9. (Pubitemid 14187653)
31. Villacampa MJ, Lampreave F, Calvo M, Naval J, Pineiro A, Uriel J. Incorporation of radiolabelled alpha-fetoprotein in the brain and other tissues of the developing rat. Dev Brain Res. 1984;12:77-82. (Pubitemid 14150256)
32. Uriel J, Faivre-Bauman A, Trojan J, Doiret D. Immunocytochemical demonstration of alpha-fetoprotein uptake by primary cultures of fetal hemisphere cells from mouse brain. Neurosci Lett. 1981;27:171-5. (Pubitemid 12169449)
33. Uriel J, Naval J, Laborda J. Alpha-fetoprotein mediated transfer of arachidonic acid into cultured cloned cells derived from a rat rhabdomyosarcoma. J Biol Chem. 1987;262:2579-3585.
34. Alava MA, Sturralde M, Lampreave F, Pineiro A. Specific uptake of alpha-fetoprotein and albumin by rat Morris 777 Hepatoma cells. Tum Biol. 1999;20:52-64. (Pubitemid 29009849)
35. Naval J, Villacampa MJ, Goguel AF, Uriel J. Cell type specific receptors for AFP in a mouse T-lymphoma cell line. Proc Nat Acad Sci USA. 1985;82:3301-4.
36. Biddle W, Sarcione EJ. Specific cytoplasmic alpha-fetoprotein binding protein in MCF-7 human breast cancer cells and primary breast cancer tissue. Breast Cancer Res Treat. 1987;10:279-86. (Pubitemid 18036275)
37. Torres JM, Laborda J, Naval J, Darracq N, Mishal Z, Uriel J. Expression of alpha-fetoprotein receptors by human T-lymphocytes during blastic transformation. Mol Immunol. 1989;26:851-7. (Pubitemid 19249462)
38. Suzuki Y, Zeng CQY, Alpert E. Isolation and characterization of a specific alpha-fetoprotein receptor on human monocytes. J Clin Invest. 1992;90:1530-6.
39. Torres JM, Geuskens M, Uriel J. Activated human T lymphocytes express albumin binding proteins which cross-react with alpha-fetoprotein. Eur J Cell Biol. 1992;57:222-8.
40. Torres JM, Carracq N, Uriel J. Membrane proteins from lymphoblastoid cells showing cross-affinity for alpha-fetoprotein and albumin: Isolation and characterization. Biochem Biophys Acta. 1992;1159:60-6.
41. Laderoute MP (1991) The characterization of a novel, widespread, PNA-reactive tumor associated antigen: The alpha-fetoprotein receptor/binding protein. Ph.D. Thesis, Faculty of Graduate Studies and Research, University of Alberta, Canada, pp 1-256.
42. Laderoute MP, Wilans D, Wegmann T, Longenecker M. The identification, isolation, and characterization of a 67-kilodalton, PNA-reactive autoantigen commonly expressed in human adenocarcinomas. Anticancer Res. 1994;14:1233-46. (Pubitemid 2125902)
43. Moro R, Tamaoki T, Wegmann TG, Longnecker BM, Laderoute MP. Monoclonal antibodies directed against a widespread oncofetal antigen: The alpha-fetoprotein receptor. Tumor Biol. 1993;14:116-30. (Pubitemid 23255791)
44. Kanevsky VY, Pozdnyakova LP, Aksenova OA, Severin SE, Karakov VY, Severin ES. Isolation and characterization of AFP-binding proteins from tumor and fetal tissues. Biochem Mol Biol Internl. 1997;41:1643-151.
45. Schnitzer JE, Sung A, Horst R, Bravo J. Preferential interaction of albumin binding proteins, gp30 and gp18 with conformationally modified albumins. J Biol Chem. 1992;267:24544-53.
46. Schnitzer JE, Bravo J. High affinity binding, endocytosis, and degradation of conformationally modified albumins. J Biol Chem. 1993;268:7562-70.
47. Schnitzer JE, Carley WW, Palade GE. Albumin interacts specifically with a 60 kD microvascular endothelial glycoprotein. Proc Natl AcadSci USA. 1988;85:6773-7.
48. Sage H, Johnson C, Bornstem P. Characterization of a novel serum albumin-binding glycoprotein secreted by endothelial cells in culture. J Biol Chem. 1984;259:3993-4007.
49. Dresel HA, Friedrich E, Via DP, Schettler G, Sinn H. Characterization of binding sites for acetylated low density lipoprotein in the rat liver in vivo and in vitro. EMBO J. 1985;4:1157-62.
50. Horiuchi S, Takata K, Maeda H, Morino Y. Scavenger function of sinusoidal liver cells. Acetylated low-density lipoprotein is endocytosed via a route distinct from formaldehyde-treated serum albumin. J Biol Chem. 1985;260:53-6. (Pubitemid 15165279)
51. Horiuchi S, Takata K, Morino Y. Purification of a receptor for formaldehyde-treated serum albumin from rat liver. J Biol Chem. 1985;260:482-8. (Pubitemid 15164077)
52. Dresel HA, Friedrich E, Via DP, Sinn H, Ziegler R, Schettler G. Binding of acetylated low density lipoprotein and maleylated bovine serum albumin to the rat liver: one or two receptors? EMBO J. 1987;6:319-26.
53. Kodama T, Reddy P, Kishimoto C, Krieger M. Purification and characterization of a bovine acetyl low density lipoprotein receptor. Proc Natl Acad Sci USA. 1988;85:9238-42. (Pubitemid 19001872)
54. Ghinea N, Fixman A, Alexandru D, Popov D, Hasu M, Ghitescu L, et al. Identification of albumin-binding proteins in capillary endothelial cells. J Cell Biol. 1988;107:231-9.
55. Ghinea N, Eskenasy M, Simionescu M, Simionescu N. Endothelial albumin binding proteins are membrane-associated components exposed on the cell surface. J Biol Chem. 1989;264:4755-8. (Pubitemid 19092877)
56. Moroianu J, Simionescu M. Affinity isolation of albumin-binding proteins using nitrocellulose-bound albumin. Eur J Cell Biol. 1989;50:447-52. (Pubitemid 20026982)
57. Ottnad E, Via DP, Sinn H, Friedrich E, Ziegler R, Dresel HA. Binding characteristics of reduced hepatic receptors for acetylated low-density lipoprotein and maleylated bovine serum albumin. Biochem J. 1990;265:689-98. (Pubitemid 20053871)
58. Moroianu J, Hillebrand A, Simionescu M. Albumin binding proteins are highly expressed in actively proliferating fetal and adult tissues. Eur J Cell Biol. 1990;53:20-6. (Pubitemid 20368181)
59. Ottnad E, Via DP, Frubis J, Sinn H, Friedrich E, Ziegler R, et al. Differentiation of binding sites on reconstituted hepatic scavenger receptors using oxidized low-density lipoprotein. Biochem J. 1992;281:745-51.
60. Schnitzer JE, Oh P. Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins. J Biol Chem. 1994;269:6072-82.
61. Tiruppathi C, Song W, Bergenfeldt M, Sass P, Malik AB. Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway. J Biol Chem. 1997;272:25968-75. (Pubitemid 27438924)
62. Bito R, Hino S, Baba A, Tanaka M, Watabe H, Kawabata H. Degradation of oxidative stress-induced denatured albumin in rat liver endothelial cells. Am J Physiol Cell Physiol. 2005;289:531-42.
63. Schnitzer JE, Ulmer JB, Palade GE. A major endothelial plasmalemmal sialoglycoprotein, gp60, is immunologically related to glycophorin. Proc Natl Acad Sci USA. 1990;87:6843-7.
64. Mizejewski GJ. Alpha-fetoprotein signal sequences A proposed mechanism for localization and organelle targeting. J Theor Biol. 1995;176:103-13.
65. Ockner RK, Weisigner RA, Gollan JL. Hepatic uptake of albumin-bound substances: the albumin receptor concept. Amer J Physiol. 1983;245:613-8. Gastrointest. Liver Physiol Section.
66. Uriel J, Torres JM, Anel A. Carrier protein-mediated enhancement of fatty acids transfer into human T-lymphocytes. Biochim Biophys Acta. 1994;1220:231-40.
67. Torres JM, Anel A, Uriel J. AFP-mediated uptake of fatty acids by human T-lymphocytes. J Cell Physiol. 1992;150:456-62.
68. Esteban C, Terrier P, Frayssinet C, Uriel J. Expression of the alpha-fetoprotein gene in human breast cancer. Tumour Biol. 1996;17(5):299-305. (Pubitemid 26276123)
69. Newby D, Dalgliesh G, Lyall F, Aitken DA. Alphafetoprotein and alphafetoprotein receptor expression in the normal human placenta at term. Placenta. 2005;26:190-200. (Pubitemid 40247007)
70. Butler EL, Dashe JS, Ramus RM. Association between maternal serum alpha-fetoprotein and adverse outcomes in pregnancies with placenta previa. Obstet Gynecol. 2001;97:35-8. (Pubitemid 32057152)
71. Koster EL, Dashe JS, McIntire DD, Ramus RM. Association of maternal serum alpha-fetoprotein with persistent placenta previa. J Matern Fetal Neonatal Med. 2004;16:3-7. (Pubitemid 39304362)
72. Duc-Goiran P, Mignot TM, Robert B, Machavoine F, Mondon F, Hagnere AM, et al. Expression and localization of alpha-fetoprotein mRNA and protein in human early villous trophoblasts. Placenta. 2006;27:812-21. (Pubitemid 44191833)
73. Lafuste P, Robert B, Mondon F, Danan JL, Rossi B, Duc-Goiran P, et al. Alpha-fetoprotein gene expression in early and full-term human trophoblast. Placenta. 2002;23:600-12. (Pubitemid 37184670)
74. Lambot N, Lybaert P, Boom A, Delogne-Desnoeck J, Vanbellinghen AM, Graff G, et al. Evidence for a clathrin-mediated recycling of albumin in human term placenta. Biol Reprod. 2006;75:90-7. (Pubitemid 43946343)
75. Pelikan DM, Kanhai HH, De Groot-Swings GM, Mesker WE, Tanke HJ, Scherjon SA. Fetomaternal hemorrhage in relation to chorionic villus sampling revisited. Prenat Diagn. 2006;26:201-5.
76. Palm NW, Medzhitov R. Pattern recognition receptors and control of adaptive immunity. Immunol Rev. 2009;227:221-33.
77. Greaves DR, Gordon S. Recent insights into the biology of macrophage scavenger receptors. J Lipid Res. 2005;46:11-20. (Pubitemid 40066666)
78. Cao WM, Murao K, Imachi H, Yu X, Abe H, Yamauchi A, et al. A mutant high-density lipoprotein receptor inhibits proliferation of human breast cancer cells. Cancer Res. 2004;64(4):1514-21.
79. Hu W, Zhen X, Xiong B, Wang B, Zhang W, Zhou W. CXCR6 is expressed in human prostate cancer in vivo and is involved in the in vitro invasion of PC3 and LNCap cells. Cancer Sci. 2008;99(7):1362-9. (Pubitemid 351761725)
80. Czokalo M, Tomasiak M. Alpha-fetoprotein inhibits aggregation of human platelets. Haematologia. 1989;22:11-8. (Pubitemid 19072828)
81. Korporaal SJ, Van Eck M, Adelmeijer J, Ljsseldjk M, Out R, Lisman T, et al. Platelet activation by oxidized low density lipoprotein is mediated by CD36 and scavenger receptor-A. Arterioscler Thromb Vasc Biol. 2007;27:2476-83. (Pubitemid 350203967)
82. Liang M, Zhang P, Fu J. Up-regulation of LOX-1 expression by TNF-alpha promotes trans-endothelial migration of MDA-MB-231 breast cancer cells. Cancer Lett. 2007;258:31-7. (Pubitemid 47600486)
83. Butterstein GM, Morrison J, Mizejewski GJ. Effect of alpha-fetoprotein and derived peptides on insulin-and estrogen-induced fetotoxicity. Fetal Deagn Ther. 2003;125:1080-9.
84. Marwali MR, Hu CP, Mohandas B, Dandapat A, Deonikar P, Chen J, et al. Modulation of ADP-induced platelet activation by aspirin and pravastatin: role of lectin-like oxidized low-density lipoprotein receptor-1, nitric oxide, oxidative stress, and inside-out integrin signaling. J Pharmacol Exp Ther. 2007;322:1324-32. (Pubitemid 47295783)
85. Butterstein GM, Mizejewski GJ. Alpha-fetoprotein inhibits frog metamorphosis: implications for protein motif conservation. Comp Biochem Physiol. 1999;124A:39-45.
86. Jurgens JB, Gartland LA, DuPasquier L, Horton JD, Gobel TW, Cooper MD. Identification of a candidate CD5 homologue in the amphibian Xenopus laevis. J Immunol. 1995;155:4218-23.
87. Terentiev AA, Moldogazieva NT. Cell adhesion proteins and alpha-fetoprotein. Similar structural motifs as prerequisites for common functions. Biochemistry. 2007;72:920-35.
88. i/e and formation of focal adhesion complexes. J Lipid Res. 2002;43:1829-36.
89. Liang OD, Korff T, Eckhardt J, Rifaat J, Baal N, Herr F, et al. Oncodevelopmental alphafetoprotein acts as a selective proangiogenic factor on endothelial cells from the fetomaternal unit. J Clin Endocrinol Metabolism. 2004;89:1415-22. (Pubitemid 38368446)
90. Hu C, Dandapat A, Mehta JL. Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway. Hypertension. 2007;50:952-7. (Pubitemid 350287540)
91. Selman L, Skjodt K, Nielsen O, Floridon C, Holmskov U, Hansen S. Expression and tissue localization of collectin placenta 1 (CL-P1, SRCL) in human tissues. Mol Immunol. 2008;45:3278-88.
92. Mizejewski GJ, Vonnegut M, Jacobsen HI. Estradiol-activated alpha-fetoprotein suppressed the uterotropic response to estrogens. Proc. Soc. Natl Acad. Sci USA. 1983;2733-7.
93. Keenihan SN, Robertson SA. Diversity in phenotype and steroid hormone dependence in dendritic cells and macrophages in the mouse uterus. Biol Reprod. 2004;70:1562-72. (Pubitemid 38715608)
94. Bartha JL, Romero-Carmona R, Comino-Delgado R, Arce F, Arrabal J. AFP and hematopoietic growth factors in amniotic fluids. Obstet Gynecol. 2000;96:588-92.
95. Holm TM, Braun A, Trigatti BL, Brugnara C, Sakamoto M, Krieger M, et al. Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-Bl. Blood. 2002;99:1817-24. (Pubitemid 34533058)
96. Seralini GE, Stora C. Inhibition of murine genital function by alpha-fetoprotein. Tumour Biol. 1997;8:292-3.
97. Binder RJ, Vatner R, Srivastava P. The heat-shock protein receptors: some answers and more questions. Tissue Antigens. 2004;64:442-51. (Pubitemid 39312725)
98. Koths K, Taylor E, Halenback R, Casipit C, Wang A. Cloning and characterization of a human Mac-2-binding protein, a new member of the superfamily defined by the macrophage scavenger receptor cysteine-rich domain. J Biol Chem. 1993;268 (19):14245-1429.
99. Nakayama T, Hieshima K, Izawa D, Tatsumi Y, Kanamaru A, Yoshie O. Cutting edge: profile of chemokine receptor expression on human plasma cells accounts for their efficient recruitment to target tissues. J Immunol. 2003;170(3):1136-40. (Pubitemid 36139476)
100. Tran-Thanh D, Done SJ. The role of stromal factors in breast tumorigenicity. Am J Pathol. 2010;176:1072-4.
101. Satoh H, Kiyota E, Terasake Y, Sawamura T, Takagi K, Mizuta H, et al. Expression and localization of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in murine and human placentas. J Histochem Cytochem. 2008;56:773-84. (Pubitemid 351991090)
102. Huang Y, Zhu XY, Du MR, Li DJ. Human trophoblasts recruited T-lymphocytes and monocytes into deciduas by secretion of chemokine CXCL16 and interaction with CXCR6 in the first-trimester pregnancy. J Immunol. 2008;180:2367-75.
103. Elshourbagy NA, Li X, Terrett J, VanHorn S, Gross MS, Adamou JE, et al. Molecular characterization of a human scavenger receptor, human MARCO. Eur J Biochem. 2000;267:919-26. (Pubitemid 30082407)
104. Sahoo D, Drover VA. The role of scavenger receptors in signaling, inflammation, and atherosclerosis. In: Cheema SK, editors. Biochemistry of atherosclerosis. New York: Springer; 2006, p. 53-69.
105. Leito JT, Ligtenberg AJ, Naxmi K, de Blieck-Hogervorst JM, Veerman EC, Nieuw Amerongen AV. A common binding motif for various bacteria of the bacteria-binding peptide SRCRP2 of DMBT1/gp-340/salivary agglutinin. Bio Chem. 2008;389:1193-200.
106. Bikker FJ, Ligtenberg AJ, End C, Renner M, Blaich S, Lyer S, et al. Bacteria binding by DMBT1/SAGgp-340 is confined to the VEVLXXXXW motif in its scavenger receptor cysteine-rich domains. J Biol Chem. 2004;279:47699-703. (Pubitemid 39540916)
107. Koba H, Okuda K, Watanabe H, Tagami J, Senpuku H. Role of lysine in interaction between surface protein peptides of Streptococcus gordonii and agglutinin peptide. Oral Microbiol Immuno. 2009;24:162-9.
108. Beauvillain C, Meloni F, Sirard JC, Blanchard S, Jarry U, Scotet M, et al. The scavenger receptors SRA-1 and SREC-I cooperate with TLR2 in the recognition of the hepatitis C virus non-structural protein 3 by dendritic cells. J Hepatol. 2010;52:644-51.
109. Ishii J, Adachi H, Aoki J, Koizumi H, Tomita S, Suzuki T, et al. SREC-II, a new member of the scavenger receptor type F family, trans-interacts with SREC-I through its extracellular domain. J Biol Chem. 2002;277:39696-702. (Pubitemid 35190952)
110. Delneste Y. Scavenger receptors and heat-shock protein-mediated antigen cross-presentation. Biochem Soc Trans. 2004;32:633-5. (Pubitemid 39120402)
111. Truong TQ, Brodeur MR, Falstrault L, Rhainds D, Brissette L. Expression of caveolin-1 in hepatic cells increases oxidized LDL uptake and preserves the expression of lipoprotein receptors. J Cell Biochem. 2009;108:906-15.
112. Hsu HY, Hajjar DP, Khan F, Falcone DJ (1998) Ligand binding to macrophage scavenger receptor-A induces urokinase-type plasminogen activator expression by a protein kinase-dependent signaling pathway. 273:1240-1246.
113. Mori T, Takahashi K, Naito M, Kodama T, Hakamata H, Sakai M, et al. Endocytic pathway of scavenger receptors via trans-Golgi system in bovine alveolar macrophages. Lab Invest. 1994;71:409-16. (Pubitemid 2156828)
114. Whitman SC, Daugherty A, Post SR. Regulation of acetylated low density lipoprotein uptake in macrophages by pertussis toxin-sensitive G proteins. J Lipid Res. 2000;41:807-13. (Pubitemid 30314136)
115. Takeshi M, Sakai M, Kobori S, Biwa T, Takemura T, Matsuda H, et al. Two intracellular signaling pathways for activation of protein kinase C are involved in oxidized low-density lipoprotein-induced macrophage growth. Arterioscler Thromb Vasc Biol. 1997;17:3013-20. (Pubitemid 28016054)
116. Miki S, Tsukada S, Nakamura Y, Aimoto S, Hojo H, Sato B, et al. Functional and possible physical association of scavenger receptor with cytoplasmic tyrosine kinase lyn in monocytic THP-1-derived macrophages. FEBS Lett. 1996;399: 241-4. (Pubitemid 26426858)
117. Scheuermann RH, Racila E, Tucker T, Yefenof E, Street NE, Vitetta ES, et al. Lyn tyrosine kinase signals cell cycle arrest but not apoptosis in B-lineage lymphoma cells. Proc Natl Acad Sci USA. 1994;91:4048-52.
118. Cao W, Calabro V, Root A, Yan G, Lam K, Olland S, et al. Oligomerization is required for the activity of recombinant soluble LOX-1. FEBS J. 2009;276:4909-20.
119. Navarro-Tito N, Robledo T, Salazar EP. Arachiodonic acid promotes FAK activation and migration in MDA-MB-213 breast cancer cells. Exp Cell Res. 2008;314:3340-55.
120. Dole VS, Matuskova J, Vasile E, Yesilaltay A, Bergmeier W, Bernimoulin M, et al. Thrombocytopenia and platelet abnormalities in high-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2008;28:1111-6.