Down-regulation of the tumor suppressor C-terminal Src kinase (Csk)-binding protein (Cbp)/PAG1 is mediated by epigenetic histone modifications via the Mitogen-activated Protein Kinase (MAPK)/Phosphatidylinositol 3-Kinase (PI3K) pathway

Journal of Biological Chemistry

Volumn 286, Issue 18, 2011, Pages 15698-15706

  Suzuki, Kei ^a   Oneyama, Chitose ^a   Kimura, Hironobu ^b   Tajima, Shoji ^b   Okada, Masato ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; BINDING PROTEINS; C-TERMINAL SRC KINASE; CANCER CELLS; CPG ISLANDS; DNA METHYLATION; DOWN-REGULATION; HISTONE DEACETYLASES; HISTONE H3; HISTONE H4; HISTONE MODIFICATION; HUMAN CANCER CELLS; HYPOMETHYLATION; MITOGEN ACTIVATED PROTEIN KINASE; MOUSE EMBRYONIC FIBROBLASTS; PHOSPHATIDYLINOSITOL 3-KINASE; TRANSCRIPTIONAL ACTIVITY; TRANSMEMBRANES; TRIMETHYLATION; TUMOR PROGRESSIONS; TUMOR SUPPRESSORS;

ACETYLATION; AMINO ACIDS; CELL CULTURE; CELLS; DISEASES; NUCLEIC ACIDS; RESTORATION; TUMORS;

ENZYMES;

ADAPTOR PROTEIN; C TERMINAL SRC KINASE BINDING PROTEIN; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE H3; HISTONE H3 LYSINE 27; HISTONE H4; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; EPIGENETICS; FIBROBLAST; HISTONE ACETYLATION; HISTONE METHYLATION; HISTONE MODIFICATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; EMBRYO, MAMMALIAN; EPIGENESIS, GENETIC; FIBROBLASTS; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE INHIBITORS; HISTONES; HUMANS; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; METHYLATION; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOPROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RAS PROTEINS; TUMOR SUPPRESSOR PROTEINS;

EID: 79955530689     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.195362     Document Type: Article

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