Silibinin in vitro protects A549 cells from staphylococcus aureus-mediated injury and in vivo alleviates the lung injury of staphylococcal pneumonia

Planta Medica

Volumn 79, Issue 2, 2013, Pages 110-115

  Wang, Xin ^a   Dong, Jing ^a   Dai, Xiaohan ^a   Zhang, Yu ^a   Wang, Jianfeng ^a   Li, Hongen ^a   Lu, Chongjian ^a   Tan, Wei ^a   Gao, Xiaohan ^a   Deng, Xuming ^a   Bu, Shijin ^b   Niu, Xiaodi ^a  

^a JILIN UNIVERSITY   (China)

^b YANGZHOU UNIVERSITY   (China)

Author keywords

toxin; A549 cells; Asteraceae; pneumonia; silibinin; Silybum marianum; Staphylococcus aureus

Indexed keywords

ALPHA TOXIN; SILIBININ;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG INJURY; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAPHYLOCOCCAL PNEUMONIA; STAPHYLOCOCCUS AUREUS; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; BACTERIAL TOXINS; BLOTTING, WESTERN; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEMOLYSIN PROTEINS; HEMOLYSIS; HUMANS; INHIBITORY CONCENTRATION 50; LUNG; LUNG INJURY; MICE; MICROBIAL SENSITIVITY TESTS; PNEUMONIA, STAPHYLOCOCCAL; RABBITS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SILYMARIN; STAPHYLOCOCCUS AUREUS;

ASTERACEAE; SILYBUM MARIANUM; STAPHYLOCOCCUS AUREUS;

EID: 84873059749     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0032-1328068     Document Type: Article

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