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Volumn 30, Issue 2, 2013, Pages 217-227

Analysis of the inhibition potential of zosuquidar derivatives on selected bacterial and fungal ABC transporters

Author keywords

ABC transporter; Inhibitor; Multidrug resistance; Pleiotropic drug resistance; Transport; Zosuquidar

Indexed keywords

ABC TRANSPORTER; LEAD; RHODAMINE 6G; ZOSUQUIDAR;

EID: 84873050654     PISSN: 09687688     EISSN: 14645203     Source Type: Journal    
DOI: 10.3109/09687688.2012.758876     Document Type: Article
Times cited : (6)

References (37)
  • 1
    • 1642565130 scopus 로고    scopus 로고
    • Reversible transport by the ATP-binding cassette multidrug export pump LmrA: ATP synthesis at the expense of downhill ethidium uptake
    • Balakrishnan L, Venter H, Shilling RA, Van Veen HW. 2004. Reversible transport by the ATP-binding cassette multidrug export pump LmrA: ATP synthesis at the expense of downhill ethidium uptake. J Biol Chem 279:11273-11280.
    • (2004) J Biol Chem , vol.279 , pp. 11273-11280
    • Balakrishnan, L.1    Venter, H.2    Shilling, R.A.3    Van Veen, H.W.4
  • 2
    • 0023917654 scopus 로고
    • A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay
    • Baykov AA, Evtushenko OA, Avaeva SM. 1988. A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay. Anal Biochem 171:266-270.
    • (1988) Anal Biochem , vol.171 , pp. 266-270
    • Baykov, A.A.1    Evtushenko, O.A.2    Avaeva, S.M.3
  • 3
    • 0034643830 scopus 로고    scopus 로고
    • Prenyl-flavonoids as potent inhibitors of the Pdr5p multidrug ABC transporter from Saccharomyces cerevisiae
    • Conseil G, Decottignies A, Jault JM, Comte G, Barron D, Goffeau A, et al. 2000. Prenyl-flavonoids as potent inhibitors of the Pdr5p multidrug ABC transporter from Saccharomyces cerevisiae. Biochemistry 39:6910-6917.
    • (2000) Biochemistry , vol.39 , pp. 6910-6917
    • Conseil, G.1    Decottignies, A.2    Jault, J.M.3    Comte, G.4    Barron, D.5    Goffeau, A.6
  • 4
    • 0043207603 scopus 로고    scopus 로고
    • Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydro-phobic estradiol-derivative RU49953
    • Conseil G, Perez-Victoria JM, Renoir JM, Goffeau A, Di Pietro A. 2003. Potent competitive inhibition of drug binding to the Saccharomyces cerevisiae ABC exporter Pdr5p by the hydro-phobic estradiol-derivative RU49953. Biochim Biophys Acta 1614:131-134.
    • (2003) Biochim Biophys Acta , vol.1614 , pp. 131-134
    • Conseil, G.1    Perez-Victoria, J.M.2    Renoir, J.M.3    Goffeau, A.4    Di Pietro, A.5
  • 5
    • 0035030729 scopus 로고    scopus 로고
    • Reversal of mul-tidrug resistance by the P-glycoprotein modulator, LY335979, from the bench to the clinic
    • Dantzig AH, Law KL, Cao J, Starling JJ. 2001. Reversal of mul-tidrug resistance by the P-glycoprotein modulator, LY335979, from the bench to the clinic. Curr Med Chem 8:39-50.
    • (2001) Curr Med Chem , vol.8 , pp. 39-50
    • Dantzig, A.H.1    Law, K.L.2    Cao, J.3    Starling, J.J.4
  • 7
    • 0031905588 scopus 로고    scopus 로고
    • Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter
    • Egner R, Rosenthal FE, Kralli A, Sanglard D, Kuchler K. 1998. Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter. Mol Biol Cell 9:523-543.
    • (1998) Mol Biol Cell , vol.9 , pp. 523-543
    • Egner, R.1    Rosenthal, F.E.2    Kralli, A.3    Sanglard, D.4    Kuchler, K.5
  • 8
    • 42449109037 scopus 로고    scopus 로고
    • A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5
    • Ernst R, Kueppers P, Klein CM, Schwarzmueller T, Kuchler K, Schmitt L. 2008. A mutation of the H-loop selectively affects rhodamine transport by the yeast multidrug ABC transporter Pdr5. Proc Natl Acad Sci USA 105:5069-5074.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5069-5074
    • Ernst, R.1    Kueppers, P.2    Klein, C.M.3    Schwarzmueller, T.4    Kuchler, K.5    Schmitt, L.6
  • 11
    • 0037458550 scopus 로고    scopus 로고
    • Studies with novel Pdr5p substrates demonstrate a strong size dependence for xenobiotic efflux
    • Golin J, Ambudkar SV, Gottesman MM, Habib AD, Sczepanski J, Ziccardi W, et al. 2003. Studies with novel Pdr5p substrates demonstrate a strong size dependence for xenobiotic efflux. J Biol Chem 278:5963-5869.
    • (2003) J Biol Chem , vol.278 , pp. 5963-5869
    • Golin, J.1    Ambudkar, S.V.2    Gottesman, M.M.3    Habib, A.D.4    Sczepanski, J.5    Ziccardi, W.6
  • 12
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE. 2002. Multidrug resistance in cancer: Role of ATP-dependent transporters. Nat Rev Cancer 2:48-58.
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 13
    • 0028341190 scopus 로고
    • Fluorescence lifetime analysis of DNA intercalated ethidium bromide and quenching by free dye
    • Heller DP, Greenstock CL. 1994. Fluorescence lifetime analysis of DNA intercalated ethidium bromide and quenching by free dye. Biophys Chem 50:305-312.
    • (1994) Biophys Chem , vol.50 , pp. 305-312
    • Heller, D.P.1    Greenstock, C.L.2
  • 16
    • 34548724460 scopus 로고    scopus 로고
    • Distribution and physiology of ABC-type transporters contributing to multidrug resistance in bacteria
    • Lubelski J, Konings WN, Driessen AJ. 2007. Distribution and physiology of ABC-type transporters contributing to multidrug resistance in bacteria. Microbiol Mol Biol Rev 71:463-476.
    • (2007) Microbiol Mol Biol Rev , vol.71 , pp. 463-476
    • Lubelski, J.1    Konings, W.N.2    Driessen, A.J.3
  • 17
    • 4544337748 scopus 로고    scopus 로고
    • YdaG and ydbA of Lactococcus lactis encode a heterodimeric ATP-binding cassette-type multidrug transporter
    • Lubelski J, Mazurkiewicz P, Van Merkerk R, Konings WN, Driessen AJ. 2004. ydaG and ydbA of Lactococcus lactis encode a heterodimeric ATP-binding cassette-type multidrug transporter. J Biol Chem 279:34449-34455.
    • (2004) J Biol Chem , vol.279 , pp. 34449-34455
    • Lubelski, J.1    Mazurkiewicz, P.2    Van Merkerk, R.3    Konings, W.N.4    Driessen, A.J.5
  • 18
    • 30744465085 scopus 로고    scopus 로고
    • Nucleotide-binding sites of the heterodimeric LmrCD ABC-multidrug transporter of Lactococcus lactis are asymmetric
    • Lubelski J, Van Merkerk R, Konings WN, Driessen AJ. 2006b. Nucleotide-binding sites of the heterodimeric LmrCD ABC-multidrug transporter of Lactococcus lactis are asymmetric. Biochemistry 45:648-656.
    • (2006) Biochemistry , vol.45 , pp. 648-656
    • Lubelski, J.1    Van Merkerk, R.2    Konings, W.N.3    Driessen, A.J.4
  • 19
    • 73749084037 scopus 로고    scopus 로고
    • Regulation of multidrug resistance in pathogenic fungi
    • Morschhauser J. 2010. Regulation of multidrug resistance in pathogenic fungi. Fungal Genet Biol 47:94-106.
    • (2010) Fungal Genet Biol , vol.47 , pp. 94-106
    • Morschhauser, J.1
  • 22
    • 33646251815 scopus 로고    scopus 로고
    • Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria
    • Piddock LJ. 2006a. Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria. Clin Microbiol Rev 19:382-402.
    • (2006) Clin Microbiol Rev , vol.19 , pp. 382-402
    • Piddock, L.J.1
  • 23
    • 33747154459 scopus 로고    scopus 로고
    • Multidrug-resistance efflux pumps-not just for resistance
    • Piddock LJ. 2006b. Multidrug-resistance efflux pumps-not just for resistance. Nat Rev Microbiol 4:629-636.
    • (2006) Nat Rev Microbiol , vol.4 , pp. 629-636
    • Piddock, L.J.1
  • 24
    • 0028928549 scopus 로고
    • Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals
    • Prasad R, De Wergifosse P, Goffeau A, Balzi E. 1995. Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals. Curr Genet 27:320-329.
    • (1995) Curr Genet , vol.27 , pp. 320-329
    • Prasad, R.1    De Wergifosse, P.2    Goffeau, A.3    Balzi, E.4
  • 25
    • 70350026151 scopus 로고    scopus 로고
    • Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation
    • Sanglard D, Coste A, Ferrari S. 2009. Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation. FEMS Yeast Res 9:1029-1050.
    • (2009) FEMS Yeast Res , vol.9 , pp. 1029-1050
    • Sanglard, D.1    Coste, A.2    Ferrari, S.3
  • 26
    • 0029061103 scopus 로고
    • Reconstitution of drug transport by purified P-glycoprotein
    • Shapiro AB, Ling V. 1995. Reconstitution of drug transport by purified P-glycoprotein. J Biol Chem 270:16167-16175.
    • (1995) J Biol Chem , vol.270 , pp. 16167-16175
    • Shapiro, A.B.1    Ling, V.2
  • 27
    • 0030782511 scopus 로고    scopus 로고
    • Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities
    • Shapiro AB, Ling V. 1997. Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities. Eur J Biochem 250:130-137.
    • (1997) Eur J Biochem , vol.250 , pp. 130-137
    • Shapiro, A.B.1    Ling, V.2
  • 28
    • 0026457090 scopus 로고
    • Synthesis and biological activity of 4-(diphenylmethyl)-alpha-[(4- quinoliny-loxy)methyl]-1-piperazineethanol and related compounds
    • Sircar I, Haleen SJ, Burke SE, Barth H. 1992. Synthesis and biological activity of 4-(diphenylmethyl)-alpha-[(4-quinoliny-loxy)methyl]-1- piperazineethanol and related compounds. J Med Chem 35:4442-4449.
    • (1992) J Med Chem , vol.35 , pp. 4442-4449
    • Sircar, I.1    Haleen, S.J.2    Burke, S.E.3    Barth, H.4
  • 29
    • 0038035675 scopus 로고    scopus 로고
    • Zosuquidar trihydrochloride-multidrug resistance modulator P-glycopro-tein (MDR-1) inhibitor
    • Sorbera LA, Castaner J, Silvestre JS, Bayes M. 2003. Zosuquidar trihydrochloride-multidrug resistance modulator P-glycopro-tein (MDR-1) inhibitor. Drugs Future 28:125-136.
    • (2003) Drugs Future , vol.28 , pp. 125-136
    • Sorbera, L.A.1    Castaner, J.2    Silvestre, J.S.3    Bayes, M.4
  • 30
    • 0030769833 scopus 로고    scopus 로고
    • Pharmacological characterization of LY335979: A potent cyclopropyldibenzosuberane modulator of P-glycoprotein
    • Starling JJ, Shepard RL, Cao J, Law KL, Norman BH, Kroin JS, et al. 1997. Pharmacological characterization of LY335979: A potent cyclopropyldibenzosuberane modulator of P-glycoprotein. Adv Enzyme Regul 37:335-347.
    • (1997) Adv Enzyme Regul , vol.37 , pp. 335-347
    • Starling, J.J.1    Shepard, R.L.2    Cao, J.3    Law, K.L.4    Norman, B.H.5    Kroin, J.S.6
  • 31
    • 0030943029 scopus 로고    scopus 로고
    • Structure-activity relationship of newly synthesized quin-oline derivatives for reversal of multidrug resistance in cancer
    • Suzuki T, Fukazawa N, San-Nohe K, Sato W, Yano O, Tsuruo T. 1997. Structure-activity relationship of newly synthesized quin-oline derivatives for reversal of multidrug resistance in cancer. J Med Chem 40:2047-2052.
    • (1997) J Med Chem , vol.40 , pp. 2047-2052
    • Suzuki, T.1    Fukazawa, N.2    San-Nohe, K.3    Sato, W.4    Yano, O.5    Tsuruo, T.6
  • 34
    • 0032518394 scopus 로고    scopus 로고
    • A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene
    • Van Veen HW, Callaghan R, Soceneantu L, Sardini A, Konings WN, Higgins CF. 1998. A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene. Nature 391:291-295.
    • (1998) Nature , vol.391 , pp. 291-295
    • Van Veen, H.W.1    Callaghan, R.2    Soceneantu, L.3    Sardini, A.4    Konings, W.N.5    Higgins, C.F.6
  • 35
    • 0034212332 scopus 로고    scopus 로고
    • The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism
    • Van Veen HW, Margolles A, Muller M, Higgins CF, Konings WN. 2000. The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. EMBO J 19:2503-2514.
    • (2000) EMBO J , vol.19 , pp. 2503-2514
    • Van Veen, H.W.1    Margolles, A.2    Muller, M.3    Higgins, C.F.4    Konings, W.N.5
  • 36
    • 0029744881 scopus 로고    scopus 로고
    • Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1
    • Van Veen HW, Venema K, Bolhuis H, Oussenko I, Kok J, Poolman B, et al. 1996. Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1. Proc Natl Acad Sci USA 93:10668-10672.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10668-10672
    • Van Veen, H.W.1    Venema, K.2    Bolhuis, H.3    Oussenko, I.4    Kok, J.5    Poolman, B.6
  • 37
    • 37349115703 scopus 로고    scopus 로고
    • On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA
    • Venter H, Velamakanni S, Balakrishnan L, Van Veen HW. 2008. On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA. Biochem Pharmacol 75:866-874.
    • (2008) Biochem Pharmacol , vol.75 , pp. 866-874
    • Venter, H.1    Velamakanni, S.2    Balakrishnan, L.3    Van Veen, H.W.4


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