Structure-activity relationship of newly synthesized quinoline derivatives for reversal of multidrug resistance in cancer

Journal of Medicinal Chemistry

Volumn 40, Issue 13, 1997, Pages 2047-2052

  Suzuki, Tsuneji ^a   Fukazawa, Nobuyuki ^a   San nohe, Kunio ^a   Sato, Wakao ^b   Yano, Osamu ^b   Tsuruo, Takashi ^c  

^a Life Science Laboratory   (Japan)

^b Mitsui Pharmaceuticals Inc   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 [3 (4 DIPHENYLACETYL 1 PIPERAZINYL) 2 HYDROXYPROPOXY]QUINOLINE; 5 [3 [4 (10,11 DIHYDRO 5H DIBENZO[A,D]CYCLOHEPTAN 5 YL)PIPERAZIN 1 YL] 2 HYDROXYPROPOXY]QUINOLIN; GLYCOPROTEIN P; HYDROGEN; MS 073; NITROGEN; PIPERAZINE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; VERAPAMIL; VINCRISTINE;

ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROGEN BOND; MALIGNANT NEOPLASTIC DISEASE; MULTIDRUG RESISTANCE; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; MICE; MODELS, CHEMICAL; MODELS, MOLECULAR; NEOPLASMS, EXPERIMENTAL; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; VINCRISTINE;

EID: 0030943029     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960869l     Document Type: Article

References (22)

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