3-Bromopyruvate induces endoplasmic reticulum stress, overcomes autophagy and causes apoptosis in human HCC cell lines

Anticancer Research

Volumn 30, Issue 3, 2010, Pages 923-926

  Ganapathy Kanniappan, Shanmugasundaram ^a   Geschwind, Jean Francois H ^a   Kunjithapatham, Rani ^a   Buijs, Manon ^a   Syed, Labiq H ^a   Rao, Pramod P ^a   Ota, Shinichi ^a   Kwak, Byung Kook ^a   Loffroy, Romaric ^a   Vali, Mustafa ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antiglycolytic; Autophagosome; ER stress; Translation inhibition

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; BROMOPYRUVIC ACID; CASPASE 3; FAS ANTIGEN; PROTEIN P53; PYRUVIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; CARCINOMA CELL; CELL DEATH; CELL LINE; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MOLECULAR MECHANICS; NICK END LABELING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TRANSLATION REGULATION; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; AUTOPHAGY; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; HUMANS; LIVER NEOPLASMS; PYRUVATES; STRESS, PHYSIOLOGICAL;

EID: 77951057423     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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