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Volumn 62, Issue 2, 2013, Pages 382-391

Apolipoprotein E2 accentuates postprandial inflammation and diet-induced obesity to promote hyperinsulinemia in mice

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; INSULIN; LIPID;

EID: 84873020587     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-0390     Document Type: Article
Times cited : (28)

References (44)
  • 1
    • 66349085616 scopus 로고    scopus 로고
    • Apolipoprotein E: Structure determines function, from atherosclerosis to Alzheimer's disease to AIDS
    • Mahley RW, Weisgraber KH, Huang Y. Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS. J Lipid Res 2009;50(Suppl.):S183-S188
    • (2009) J Lipid Res , vol.50 , Issue.SUPPL.
    • Mahley, R.W.1    Weisgraber, K.H.2    Huang, Y.3
  • 2
    • 66349101348 scopus 로고    scopus 로고
    • Apoprotein e as a lipid transport and signaling protein in the blood, liver, and artery wall
    • Getz GS, Reardon CA. Apoprotein E as a lipid transport and signaling protein in the blood, liver, and artery wall. J Lipid Res 2009;50(Suppl.):S156- S161
    • (2009) J Lipid Res , vol.50 , Issue.SUPPL.
    • Getz, G.S.1    Reardon, C.A.2
  • 3
    • 0022539782 scopus 로고
    • Reciprocal effects of apolipoprotein e alleles (epsilon 2 and epsilon 4) on plasma lipid levels in normolipidemic subjects
    • Eto M, Watanabe K, Ishii K. Reciprocal effects of apolipoprotein E alleles (epsilon 2 and epsilon 4) on plasma lipid levels in normolipidemic subjects. Clin Genet 1986;29:477-484
    • (1986) Clin Genet , vol.29 , pp. 477-484
    • Eto, M.1    Watanabe, K.2    Ishii, K.3
  • 4
    • 12344300720 scopus 로고    scopus 로고
    • Apolipoprotein e polymorphism in Turkish subjects with type 2 diabetes mellitus: Allele frequency and relation to serum lipid concentrations
    • Duman BS, Oztürk M, Yilmazer S, Hatemi H. Apolipoprotein E polymorphism in Turkish subjects with type 2 diabetes mellitus: allele frequency and relation to serum lipid concentrations. Diabetes Nutr Metab 2004;17:267-274
    • (2004) Diabetes Nutr Metab , vol.17 , pp. 267-274
    • Duman, B.S.1    Oztürk, M.2    Yilmazer, S.3    Hatemi, H.4
  • 5
    • 34249895023 scopus 로고    scopus 로고
    • Wellcome Trust Case Control Consortium (WTCCC). Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
    • Zeggini E, Weedon MN, Lindgren CM, et al.; Wellcome Trust Case Control Consortium (WTCCC). Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007;316:1336-1341
    • (2007) Science , vol.316 , pp. 1336-1341
    • Zeggini, E.1    Weedon, M.N.2    Lindgren, C.M.3
  • 6
    • 34249885875 scopus 로고    scopus 로고
    • A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
    • Scott LJ, Mohlke KL, Bonnycastle LL, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007;316:1341-1345
    • (2007) Science , vol.316 , pp. 1341-1345
    • Scott, L.J.1    Mohlke, K.L.2    Bonnycastle, L.L.3
  • 7
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Saxena R, Voight BF, Lyssenko V, et al.; Diabetes Genetics Initiative of Broad Institute of Harvard and MIT, Lund University, and Novartis Institutes of BioMedical Research. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007;316: 1331-1336
    • (2007) Science , vol.316 , pp. 1331-1336
    • Saxena, R.1    Voight, B.F.2    Lyssenko, V.3
  • 8
    • 42349106044 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
    • Zeggini E, Scott LJ, Saxena R, et al.; Wellcome Trust Case Control Consortium. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet 2008;40:638-645
    • (2008) Nat Genet , vol.40 , pp. 638-645
    • Zeggini, E.1    Scott, L.J.2    Saxena, R.3
  • 9
    • 78651450033 scopus 로고    scopus 로고
    • E2 allele of the apolipo-protein e gene polymorphism is predictive for obesity status in Roma minority population of Croatia
    • Zeljko HM, Škarić-Jurić T, Narancić NS, et al. E2 allele of the apolipo-protein E gene polymorphism is predictive for obesity status in Roma minority population of Croatia. Lipids Health Dis 2011;10:9
    • (2011) Lipids Health Dis , vol.10 , pp. 9
    • Zeljko, H.M.1    Škarić-Jurić, T.2    Narancić, N.S.3
  • 10
    • 77953026034 scopus 로고    scopus 로고
    • Apolipoprotein e polymorphisms and type 2 diabetes: A meta-analysis of 30 studies including 5423 cases and 8197 controls
    • Anthopoulos PG, Hamodrakas SJ, Bagos PG. Apolipoprotein E polymorphisms and type 2 diabetes: a meta-analysis of 30 studies including 5423 cases and 8197 controls. Mol Genet Metab 2010;100:283-291
    • (2010) Mol Genet Metab , vol.100 , pp. 283-291
    • Anthopoulos, P.G.1    Hamodrakas, S.J.2    Bagos, P.G.3
  • 11
    • 0034742530 scopus 로고    scopus 로고
    • The apolipoprotein e2 allele and the severity of coronary artery disease in type 2 diabetic patients
    • Kalix B, Meynet MC, Garin MC, James RW. The apolipoprotein e2 allele and the severity of coronary artery disease in type 2 diabetic patients. Diabet Med 2001;18:445-450
    • (2001) Diabet Med , vol.18 , pp. 445-450
    • Kalix, B.1    Meynet, M.C.2    Garin, M.C.3    James, R.W.4
  • 12
    • 34548478363 scopus 로고    scopus 로고
    • The presence of apolipoprotein e4 and e2 alleles augments the risk of coronary artery disease in type 2 diabetic patients
    • Vaisi-Raygani A, Rahimi Z, Nomani H, Tavilani H, Pourmotabbed T. The presence of apolipoprotein e4 and e2 alleles augments the risk of coronary artery disease in type 2 diabetic patients. Clin Biochem 2007;40:1150-1156
    • (2007) Clin Biochem , vol.40 , pp. 1150-1156
    • Vaisi-Raygani, A.1    Rahimi, Z.2    Nomani, H.3    Tavilani, H.4    Pourmotabbed, T.5
  • 14
    • 0027315427 scopus 로고
    • Prevalence of apolipoprotein e phenotypes in ischemic cerebrovascular disease. A case-control study
    • Couderc R, Mahieux F, Bailleul S, Fenelon G, Mary R, Fermanian J. Prevalence of apolipoprotein E phenotypes in ischemic cerebrovascular disease. A case-control study. Stroke 1993;24:661-664
    • (1993) Stroke , vol.24 , pp. 661-664
    • Couderc, R.1    Mahieux, F.2    Bailleul, S.3    Fenelon, G.4    Mary, R.5    Fermanian, J.6
  • 15
    • 0026571987 scopus 로고
    • Lipoprotein profile in men with peripheral vascular disease. Role of intermediate density lipoproteins and apoprotein e phenotypes
    • Sentí M, Nogués X, Pedro-Botet J, Rubiés-Prat J, Vidal-Barraquer F. Lipoprotein profile in men with peripheral vascular disease. Role of intermediate density lipoproteins and apoprotein E phenotypes. Circulation 1992;85:30-36
    • (1992) Circulation , vol.85 , pp. 30-36
    • Sentí, M.1    Nogués, X.2    Pedro-Botet, J.3    Rubiés-Prat, J.4    Vidal-Barraquer, F.5
  • 17
    • 0021367509 scopus 로고
    • Defective hepatic lipoprotein receptor binding of b-very low density lipoproteins from type III hyper-lipoproteinemic patients. Importance of apolipoprotein e
    • Hui DY, Innerarity TL, Mahley RW. Defective hepatic lipoprotein receptor binding of b-very low density lipoproteins from type III hyper-lipoproteinemic patients. Importance of apolipoprotein E. J Biol Chem 1984;259:860-869
    • (1984) J Biol Chem , vol.259 , pp. 860-869
    • Hui, D.Y.1    Innerarity, T.L.2    Mahley, R.W.3
  • 18
    • 65449131608 scopus 로고    scopus 로고
    • Inflammation associated with the postprandial lipolysis of triglyceride-rich lipoproteins by lipoprotein lipase
    • Higgins LJ, Rutledge JC. Inflammation associated with the postprandial lipolysis of triglyceride-rich lipoproteins by lipoprotein lipase. Curr Atheroscler Rep 2009;11:199-205
    • (2009) Curr Atheroscler Rep , vol.11 , pp. 199-205
    • Higgins, L.J.1    Rutledge, J.C.2
  • 19
    • 78650908286 scopus 로고    scopus 로고
    • CD11cCD18 expression is upregulated on blood monocytes during hypertriglyceridemia and enhances adhesion to vascular cell adhesion molecule-1
    • Gower RM, Wu H, Foster GA, et al. CD11c/CD18 expression is upregulated on blood monocytes during hypertriglyceridemia and enhances adhesion to vascular cell adhesion molecule-1. Arterioscler Thromb Vasc Biol 2011; 31:160-166
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 160-166
    • Gower, R.M.1    Wu, H.2    Foster, G.A.3
  • 21
    • 1442276560 scopus 로고    scopus 로고
    • Effect of postprandial hypertriglyceridemia and hyperglycemia on circulating adhesion molecules and oxidative stress generation and the possible role of simvastatin treatment
    • Ceriello A, Quagliaro L, Piconi L, et al. Effect of postprandial hypertriglyceridemia and hyperglycemia on circulating adhesion molecules and oxidative stress generation and the possible role of simvastatin treatment. Diabetes 2004;53:701-710
    • (2004) Diabetes , vol.53 , pp. 701-710
    • Ceriello, A.1    Quagliaro, L.2    Piconi, L.3
  • 22
    • 5144232464 scopus 로고    scopus 로고
    • Glycemic and insulinemic meal responses modulate postprandial hepatic and intestinal lipoprotein accumulation in obese, insulin-resistant subjects
    • Harbis A, Perdreau S, Vincent-Baudry S, et al. Glycemic and insulinemic meal responses modulate postprandial hepatic and intestinal lipoprotein accumulation in obese, insulin-resistant subjects. Am J Clin Nutr 2004;80: 896-902
    • (2004) Am J Clin Nutr , vol.80 , pp. 896-902
    • Harbis, A.1    Perdreau, S.2    Vincent-Baudry, S.3
  • 24
    • 0032128001 scopus 로고    scopus 로고
    • Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe&z.ast;2
    • Sullivan PM, Mezdour H, Quarfordt SH, Maeda N. Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe&z.ast;2. J Clin Invest 1998; 102:130-135
    • (1998) J Clin Invest , vol.102 , pp. 130-135
    • Sullivan, P.M.1    Mezdour, H.2    Quarfordt, S.H.3    Maeda, N.4
  • 25
    • 0030741533 scopus 로고    scopus 로고
    • Targeted replacement of the mouse apolipoprotein e gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis
    • Sullivan PM, Mezdour H, Aratani Y, et al. Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. J Biol Chem 1997;272:17972-17980
    • (1997) J Biol Chem , vol.272 , pp. 17972-17980
    • Sullivan, P.M.1    Mezdour, H.2    Aratani, Y.3
  • 26
    • 0025257612 scopus 로고
    • Restriction isotyping of human apolipoprotein e by gene amplification and cleavage with HhaI
    • Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 1990;31:545-548
    • (1990) J Lipid Res , vol.31 , pp. 545-548
    • Hixson, J.E.1    Vernier, D.T.2
  • 27
    • 36049022385 scopus 로고    scopus 로고
    • Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice
    • Hofmann SM, Zhou L, Perez-Tilve D, et al. Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. J Clin Invest 2007;117:3271-3282
    • (2007) J Clin Invest , vol.117 , pp. 3271-3282
    • Hofmann, S.M.1    Zhou, L.2    Perez-Tilve, D.3
  • 28
    • 38449108309 scopus 로고    scopus 로고
    • Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipo-protein E-deficient mice
    • Hofmann SM, Perez-Tilve D, Greer TM, et al. Defective lipid delivery modulates glucose tolerance and metabolic response to diet in apolipo-protein E-deficient mice. Diabetes 2008;57:5-12
    • (2008) Diabetes , vol.57 , pp. 5-12
    • Hofmann, S.M.1    Perez-Tilve, D.2    Greer, T.M.3
  • 29
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti S, Mitchell G, Barbatelli G, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 2005;46:2347-2355
    • (2005) J Lipid Res , vol.46 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3
  • 30
    • 0038620491 scopus 로고    scopus 로고
    • Postprandial recruitment of neutrophils may contribute to endothelial dysfunction
    • van Oostrom AJHHM, Sijmonsma TP, Verseyden C, et al. Postprandial recruitment of neutrophils may contribute to endothelial dysfunction. J Lipid Res 2003;44:576-583
    • (2003) J Lipid Res , vol.44 , pp. 576-583
    • Van Oostrom, A.J.H.H.M.1    Sijmonsma, T.P.2    Verseyden, C.3
  • 32
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages inflammation and insulin resistance
    • Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol 2010;72:219-246
    • (2010) Annu Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 33
    • 77951639826 scopus 로고    scopus 로고
    • Fatty acids from very low-density lipoprotein lipolysis products induce lipid droplet accumulation in human monocytes
    • den Hartigh LJ, Connolly-Rohrbach JE, Fore S, Huser TR, Rutledge JC. Fatty acids from very low-density lipoprotein lipolysis products induce lipid droplet accumulation in human monocytes. J Immunol 2010;184:3927-3936
    • (2010) J Immunol , vol.184 , pp. 3927-3936
    • Den Hartigh, L.J.1    Connolly-Rohrbach, J.E.2    Fore, S.3    Huser, T.R.4    Rutledge, J.C.5
  • 36
    • 14544298806 scopus 로고    scopus 로고
    • Cell surface heparan sulfate proteoglycans contribute to intracellular lipid accumulation in adipocytes
    • Wilsie LC, Chanchani S, Navaratna D, Orlando RA. Cell surface heparan sulfate proteoglycans contribute to intracellular lipid accumulation in adipocytes. Lipids Health Dis 2005;4:2
    • (2005) Lipids Health Dis , vol.4 , pp. 2
    • Wilsie, L.C.1    Chanchani, S.2    Navaratna, D.3    Orlando, R.A.4
  • 37
    • 0032504182 scopus 로고    scopus 로고
    • Apolipoprotein E2 reduces the low density lipoprotein level in transgenic mice by impairing lipoprotein lipase-mediated lipolysis of triglyceride-rich lipoproteins
    • Huang Y, Liu XQ, Rall SC Jr, Mahley RW. Apolipoprotein E2 reduces the low density lipoprotein level in transgenic mice by impairing lipoprotein lipase-mediated lipolysis of triglyceride-rich lipoproteins. J Biol Chem 1998;273:17483-17490
    • (1998) J Biol Chem , vol.273 , pp. 17483-17490
    • Huang, Y.1    Liu, X.Q.2    Rall Jr., S.C.3    Mahley, R.W.4
  • 38
    • 80051825018 scopus 로고    scopus 로고
    • Expression of the human apoE2 isoform in adipocytes: Altered cellular processing and impaired adipocyte lipo-genesis
    • Huang ZH, Maeda N, Mazzone T. Expression of the human apoE2 isoform in adipocytes: altered cellular processing and impaired adipocyte lipo-genesis. J Lipid Res 2011;52:1733-1741
    • (2011) J Lipid Res , vol.52 , pp. 1733-1741
    • Huang, Z.H.1    Maeda, N.2    Mazzone, T.3
  • 39
    • 23244454385 scopus 로고    scopus 로고
    • The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor
    • Ruiz J, Kouiavskaia D, Migliorini M, et al. The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. J Lipid Res 2005;46:1721-1731
    • (2005) J Lipid Res , vol.46 , pp. 1721-1731
    • Ruiz, J.1    Kouiavskaia, D.2    Migliorini, M.3
  • 40
    • 0024449363 scopus 로고
    • The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein
    • Beisiegel U, Weber W, Ihrke G, Herz J, Stanley KK. The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein. Nature 1989; 341:162-164
    • (1989) Nature , vol.341 , pp. 162-164
    • Beisiegel, U.1    Weber, W.2    Ihrke, G.3    Herz, J.4    Stanley, K.K.5
  • 41
    • 0029951516 scopus 로고    scopus 로고
    • Very low density lipoprotein receptor binds apolipoprotein E2/2 as well as apolipoprotein E3/3
    • Takahashi S, Oida K, Ookubo M, et al. Very low density lipoprotein receptor binds apolipoprotein E2/2 as well as apolipoprotein E3/3. FEBS Lett 1996;386:197-200
    • (1996) FEBS Lett , vol.386 , pp. 197-200
    • Takahashi, S.1    Oida, K.2    Ookubo, M.3
  • 42
    • 14044262236 scopus 로고    scopus 로고
    • Two-step mechanism of binding of apolipoprotein e to heparin: Implications for the kinetics of apolipoprotein E-heparan sulfate pro-teoglycan complex formation on cell surfaces
    • Futamura M, Dhanasekaran P, Handa T, Phillips MC, Lund-Katz S, Saito H. Two-step mechanism of binding of apolipoprotein E to heparin: implications for the kinetics of apolipoprotein E-heparan sulfate pro-teoglycan complex formation on cell surfaces. J Biol Chem 2005;280:5414-5422
    • (2005) J Biol Chem , vol.280 , pp. 5414-5422
    • Futamura, M.1    Dhanasekaran, P.2    Handa, T.3    Phillips, M.C.4    Lund-Katz, S.5    Saito, H.6
  • 43
    • 0032577695 scopus 로고    scopus 로고
    • Differential cellular accumulation/retention of apolipoprotein e mediated by cell surface heparan sulfate proteoglycans. Apolipoproteins E3 and E2 greater than e4
    • Ji ZS, Pitas RE, Mahley RW. Differential cellular accumulation/retention of apolipoprotein E mediated by cell surface heparan sulfate proteoglycans. Apolipoproteins E3 and E2 greater than e4. J Biol Chem 1998;273:13452-13460
    • (1998) J Biol Chem , vol.273 , pp. 13452-13460
    • Ji, Z.S.1    Pitas, R.E.2    Mahley, R.W.3
  • 44
    • 0037453056 scopus 로고    scopus 로고
    • Triglyceride accumulation protects against fatty acid-induced lipotoxicity
    • Listenberger LL, Han X, Lewis SE, et al. Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc Natl Acad Sci USA 2003; 100:3077-3082
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3077-3082
    • Listenberger, L.L.1    Han, X.2    Lewis, S.E.3


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