메뉴 건너뛰기




Volumn 325, Issue 1-2, 2013, Pages 142-147

Decreased skeletal muscle mitochondrial DNA in patients with statin-induced myopathy

Author keywords

HMG CoA reductase inhibitors; Mitochondria; Mitochondrial DNA; Skeletal muscle; Statin; Statin induced myopathy

Indexed keywords

ATORVASTATIN; CELL NUCLEUS DNA; CERIVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; MITOCHONDRIAL DNA; SIMVASTATIN;

EID: 84872918353     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2012.12.023     Document Type: Article
Times cited : (64)

References (37)
  • 1
    • 33845876333 scopus 로고    scopus 로고
    • Risks associated with statin therapy: A systematic overview of randomized clinical trials
    • DOI 10.1161/CIRCULATIONAHA.106.624890, PII 0000301720061219000009
    • A. Kashani, C.O. Phillips, J.M. Foody, Y. Wang, S. Mangalmurti, and D.T. Ko Risks associated with statin therapy: a systematic overview of randomized clinical trials Circulation 114 25 Dec 19 2006 2788 2797 [PubMed PMID: 17159064. Epub 2006/12/13. eng] (Pubitemid 46018281)
    • (2006) Circulation , vol.114 , Issue.25 , pp. 2788-2797
    • Kashani, A.1    Phillips, C.O.2    Foody, J.M.3    Wang, Y.4    Mangalmurti, S.5    Ko, D.T.6    Krumholz, H.M.7
  • 2
    • 67249111853 scopus 로고    scopus 로고
    • Narrative review: Statin-related myopathy
    • [PubMed PMID: 19528564. Epub 2009/06/17. eng]
    • T.R. Joy, and R.A. Hegele Narrative review: statin-related myopathy Ann Intern Med 150 12 Jun 16 2009 858 868 [PubMed PMID: 19528564. Epub 2009/06/17. eng]
    • (2009) Ann Intern Med , vol.150 , Issue.12 , pp. 858-868
    • Joy, T.R.1    Hegele, R.A.2
  • 3
    • 79958264458 scopus 로고    scopus 로고
    • Statin myopathy: A common dilemma not reflected in clinical trials
    • [PubMed PMID: 21632911. Epub 2011/06/03. eng]
    • G. Fernandez, E.S. Spatz, C. Jablecki, and P.S. Phillips Statin myopathy: a common dilemma not reflected in clinical trials Cleve Clin J Med 78 6 Jun 2011 393 403 [PubMed PMID: 21632911. Epub 2011/06/03. eng]
    • (2011) Cleve Clin J Med , vol.78 , Issue.6 , pp. 393-403
    • Fernandez, G.1    Spatz, E.S.2    Jablecki, C.3    Phillips, P.S.4
  • 5
    • 35748962429 scopus 로고    scopus 로고
    • The safety of statins in clinical practice
    • DOI 10.1016/S0140-6736(07)60716-8, PII S0140673607607168
    • J. Armitage The safety of statins in clinical practice Lancet 370 9601 Nov 24 2007 1781 1790 [PubMed PMID: 17559928. Epub 2007/06/15. eng.] (Pubitemid 350137473)
    • (2007) Lancet , vol.370 , Issue.9601 , pp. 1781-1790
    • Armitage, J.1
  • 6
    • 0030889653 scopus 로고    scopus 로고
    • Compliance with treatment regimens in chronic asymptomatic diseases
    • DOI 10.1016/S0002-9343(97)00467-1, PII S0002934397004676
    • N.H. Miller Compliance with treatment regimens in chronic asymptomatic diseases Am J Med 102 2A Feb 17 1997 43 49 [PubMed PMID: 9217586. Epub 1997/02/17] (Pubitemid 27147947)
    • (1997) American Journal of Medicine , vol.102 , Issue.2 A , pp. 43-49
    • Miller, N.H.1
  • 7
    • 44949247555 scopus 로고    scopus 로고
    • Toward "pain-free" statin prescribing: Clinical algorithm for diagnosis and management of myalgia
    • DOI 10.4065/83.6.687
    • T.A. Jacobson Toward "pain-free" statin prescribing: clinical algorithm for diagnosis and management of myalgia Mayo Clin Proc 83 6 Jun 2008 687 700 [PubMed PMID: 18533086. Epub 2008/06/06. eng] (Pubitemid 351810569)
    • (2008) Mayo Clinic Proceedings , vol.83 , Issue.6 , pp. 687-700
    • Jacobson, T.A.1
  • 8
    • 76649134128 scopus 로고    scopus 로고
    • Neuromuscular symptoms and elevated creatine kinase after statin withdrawal
    • [PubMed PMID: 20147729. Epub 2010/02/12. eng]
    • A. Echaniz-Laguna, M. Mohr, and C. Tranchant Neuromuscular symptoms and elevated creatine kinase after statin withdrawal N Engl J Med 362 6 Feb 11 2010 564 565 [PubMed PMID: 20147729. Epub 2010/02/12. eng]
    • (2010) N Engl J Med , vol.362 , Issue.6 , pp. 564-565
    • Echaniz-Laguna, A.1    Mohr, M.2    Tranchant, C.3
  • 9
    • 0036787034 scopus 로고    scopus 로고
    • Statin-associated myopathy with normal creatine kinase levels
    • [PubMed PMID: 12353945. Epub 2002/10/02. eng]
    • P.S. Phillips, R.H. Haas, S. Bannykh, S. Hathaway, N.L. Gray, and B.J. Kimura Statin-associated myopathy with normal creatine kinase levels Ann Intern Med 137 7 Oct 1 2002 581 585 [PubMed PMID: 12353945. Epub 2002/10/02. eng]
    • (2002) Ann Intern Med , vol.137 , Issue.7 , pp. 581-585
    • Phillips, P.S.1    Haas, R.H.2    Bannykh, S.3    Hathaway, S.4    Gray, N.L.5    Kimura, B.J.6
  • 10
    • 67651146926 scopus 로고    scopus 로고
    • Association between statin-associated myopathy and skeletal muscle damage
    • [PubMed PMID: 19581603. Pubmed Central PMCID: 2704421. Epub 2009/07/08. eng]
    • M.G. Mohaupt, R.H. Karas, E.B. Babiychuk, V. Sanchez-Freire, K. Monastyrskaya, and L. Iyer Association between statin-associated myopathy and skeletal muscle damage CMAJ 181 1-2 Jul 7 2009 E11 E18 [PubMed PMID: 19581603. Pubmed Central PMCID: 2704421. Epub 2009/07/08. eng]
    • (2009) CMAJ , vol.181 , Issue.12
    • Mohaupt, M.G.1    Karas, R.H.2    Babiychuk, E.B.3    Sanchez-Freire, V.4    Monastyrskaya, K.5    Iyer, L.6
  • 12
    • 0027472152 scopus 로고
    • Simvastatin-induced rhabdomyolysis followed by a MELAS syndrome
    • DOI 10.1016/0002-9343(93)90129-D
    • P. Chariot, R. Abadia, D. Agnus, C. Danan, C. Charpentier, and R.K. Gherardi Simvastatin-induced rhabdomyolysis followed by a MELAS syndrome Am J Med 94 1 Jan 1993 109 110 [PubMed PMID: 8420287. Epub 1993/01/01. eng] (Pubitemid 23021180)
    • (1993) American Journal of Medicine , vol.94 , Issue.1 , pp. 109-110
    • Chariot, P.1    Abadia, R.2    Agnus, D.3    Danan, C.4    Charpentier, C.5    Gherardi, R.K.6
  • 13
    • 4444318631 scopus 로고    scopus 로고
    • Statin precipitated lactic acidosis?
    • DOI 10.1136/jcp.2004.015958
    • R. Neale, T.M. Reynolds, W. Saweirs, and J. Clin Pathol Statin precipitated lactic acidosis? J Clin Pathol 57 9 Sep 2004 989 990 [PubMed PMID: 15333664. Pubmed Central PMCID: 1770432. Epub 2004/08/31. eng] (Pubitemid 39208254)
    • (2004) Journal of Clinical Pathology , vol.57 , Issue.9 , pp. 989-990
    • Neale, R.1    Reynolds, T.M.2    Saweirs, W.3
  • 14
    • 34247849275 scopus 로고    scopus 로고
    • Statins provoking MELAS syndrome: A case report
    • DOI 10.1159/000101287
    • J.E. Thomas, N. Lee, and P.D. Thompson Statins provoking MELAS syndrome. A case report Eur Neurol 57 4 2007 232 235 [PubMed PMID: 17389800. Epub 2007/03/29. eng] (Pubitemid 46701482)
    • (2007) European Neurology , vol.57 , Issue.4 , pp. 232-235
    • Thomas, J.E.1    Lee, N.2    Thompson, P.D.3
  • 15
    • 0029113462 scopus 로고
    • Mitochondrial myopathy developing on treatment with the HMG CoA reductase inhibitors - Simvastatin and pravastatin
    • [PubMed PMID: 8540887. Epub 1995/08/01. eng]
    • J.D. England, J.C. Walsh, P. Stewart, I. Boyd, A. Rohan, and G.M. Halmagyi Mitochondrial myopathy developing on treatment with the HMG CoA reductase inhibitors - simvastatin and pravastatin Aust N Z J Med 25 4 Aug 1995 374 375 [PubMed PMID: 8540887. Epub 1995/08/01. eng]
    • (1995) Aust N Z J Med , vol.25 , Issue.4 , pp. 374-375
    • England, J.D.1    Walsh, J.C.2    Stewart, P.3    Boyd, I.4    Rohan, A.5    Halmagyi, G.M.6
  • 17
    • 0037345750 scopus 로고    scopus 로고
    • Statins unmasking a mitochondrial myopathy: A case report and proposed mechanism of disease [4]
    • B.J. Diaczok, and R. Shali Statins unmasking a mitochondrial myopathy: a case report and proposed mechanism of disease South Med J 96 3 Mar 2003 318 320 [PubMed PMID: 12659371. Epub 2003/03/28. eng] (Pubitemid 36343728)
    • (2003) Southern Medical Journal , vol.96 , Issue.3 , pp. 318-320
    • Diaczok, B.J.1    Shali, R.2
  • 18
    • 59549089180 scopus 로고    scopus 로고
    • Statin adverse effects: A review of the literature and evidence for a mitochondrial mechanism
    • [PubMed PMID: 19159124. Pubmed Central PMCID: 2849981. Epub 2009/01/23. eng]
    • B.A. Golomb, and M.A. Evans Statin adverse effects: a review of the literature and evidence for a mitochondrial mechanism Am J Cardiovasc Drugs 8 6 2008 373 418 [PubMed PMID: 19159124. Pubmed Central PMCID: 2849981. Epub 2009/01/23. eng]
    • (2008) Am J Cardiovasc Drugs , vol.8 , Issue.6 , pp. 373-418
    • Golomb, B.A.1    Evans, M.A.2
  • 19
    • 79960864934 scopus 로고    scopus 로고
    • Weighing the benefits of high-dose simvastatin against the risk of myopathy
    • PubMed PMID: 21675881. Epub 2011/06/17. eng
    • A. Egan, and E. Colman Weighing the benefits of high-dose simvastatin against the risk of myopathy N Engl J Med 365 4 Jul 28 2011 285 287 PubMed PMID: 21675881. Epub 2011/06/17. eng
    • (2011) N Engl J Med , vol.365 , Issue.4 , pp. 285-287
    • Egan, A.1    Colman, E.2
  • 20
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy - A genomewide study
    • [PubMed PMID: 18650507. Epub 2008/07/25. eng]
    • E. Link, S. Parish, J. Armitage, L. Bowman, S. Heath, and F. Matsuda SLCO1B1 variants and statin-induced myopathy - a genomewide study N Engl J Med 359 8 Aug 21 2008 789 799 [PubMed PMID: 18650507. Epub 2008/07/25. eng]
    • (2008) N Engl J Med , vol.359 , Issue.8 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, J.3    Bowman, L.4    Heath, S.5    Matsuda, F.6
  • 21
    • 33749049136 scopus 로고    scopus 로고
    • SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin
    • DOI 10.1016/j.clpt.2006.06.010, PII S0009923606002554
    • M. Niemi, M.K. Pasanen, and P.J. Neuvonen SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin Clin Pharmacol Ther 80 4 Oct 2006 356 366 [PubMed PMID: 17015053. Epub 2006/10/04. eng] (Pubitemid 44465886)
    • (2006) Clinical Pharmacology and Therapeutics , vol.80 , Issue.4 , pp. 356-366
    • Niemi, M.1    Pasanen, M.K.2    Neuvonen, P.J.3
  • 22
    • 36148953896 scopus 로고    scopus 로고
    • Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin
    • DOI 10.1038/sj.clpt.6100220, PII 6100220
    • M.K. Pasanen, H. Fredrikson, P.J. Neuvonen, and M. Niemi Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin Clin Pharmacol Ther 82 6 Dec 2007 726 733 [PubMed PMID: 17473846. Epub 2007/05/03. eng] (Pubitemid 350114817)
    • (2007) Clinical Pharmacology and Therapeutics , vol.82 , Issue.6 , pp. 726-733
    • Pasanen, M.K.1    Fredrikson, H.2    Neuvonen, P.J.3    Niemi, M.4
  • 23
    • 33751096467 scopus 로고    scopus 로고
    • SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid
    • DOI 10.1097/01.fpc.0000230416.82349.90, PII 0121301120061200000004
    • M.K. Pasanen, M. Neuvonen, P.J. Neuvonen, and M. Niemi SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid Pharmacogenet Genomics 16 12 Dec 2006 873 879 [PubMed PMID: 17108811. Epub 2006/11/17. eng] (Pubitemid 44772805)
    • (2006) Pharmacogenetics and Genomics , vol.16 , Issue.12 , pp. 873-879
    • Pasanen, M.K.1    Neuvonen, M.2    Neuvonen, P.J.3    Niemi, M.4
  • 25
    • 75549088606 scopus 로고    scopus 로고
    • The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy
    • S.P. Romaine, K.M. Bailey, A.S. Hall, and A.J. Balmforth The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy Pharmacogenomics J 10 1 2010 Feb 1 11
    • (2010) Pharmacogenomics J , vol.10 , Issue.1 , pp. 1-11
    • Romaine, S.P.1    Bailey, K.M.2    Hall, A.S.3    Balmforth, A.J.4
  • 28
    • 33748643416 scopus 로고    scopus 로고
    • Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers
    • DOI 10.1086/507132
    • E. Bua, J. Johnson, A. Herbst, B. Delong, D. McKenzie, and S. Salamat Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers Am J Hum Genet 79 3 Sep 2006 469 480 [PubMed PMID: 16909385. Pubmed Central PMCID: 1559550. Epub 2006/08/16. eng] (Pubitemid 44384256)
    • (2006) American Journal of Human Genetics , vol.79 , Issue.3 , pp. 469-480
    • Bua, E.1    Johnson, J.2    Herbst, A.3    Delong, B.4    McKenzie, D.5    Salamat, S.6    Aiken, J.M.7
  • 29
    • 79952986828 scopus 로고    scopus 로고
    • Statin or fibrate chronic treatment modifies the proteomic profile of rat skeletal muscle
    • PubMed PMID: 21300028. Epub 2011/02/09. eng
    • G.M. Camerino, M.A. Pellegrino, L. Brocca, C. Digennaro, D.C. Camerino, and S. Pierno Statin or fibrate chronic treatment modifies the proteomic profile of rat skeletal muscle Biochem Pharmacol 81 8 Apr 15 2011 1054 1064 PubMed PMID: 21300028. Epub 2011/02/09. eng
    • (2011) Biochem Pharmacol , vol.81 , Issue.8 , pp. 1054-1064
    • Camerino, G.M.1    Pellegrino, M.A.2    Brocca, L.3    Digennaro, C.4    Camerino, D.C.5    Pierno, S.6
  • 30
    • 84863657879 scopus 로고    scopus 로고
    • Opposite effects of statins on mitochondria of cardiac and skeletal muscles: A 'mitohormesis' mechanism involving reactive oxygen species and PGC-1
    • [PubMed PMID: 21775390. Epub 2011/07/22. Eng]
    • J. Bouitbir, A.L. Charles, A. Echaniz-Laguna, M. Kindo, F. Daussin, and J. Auwerx Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1 Eur Heart J Jul 20 2011 [PubMed PMID: 21775390. Epub 2011/07/22. Eng]
    • (2011) Eur Heart J
    • Bouitbir, J.1    Charles, A.L.2    Echaniz-Laguna, A.3    Kindo, M.4    Daussin, F.5    Auwerx, J.6
  • 31
    • 34147144067 scopus 로고    scopus 로고
    • Simvastatin reduces ergosterol levels, inhibits growth and causes loss of mtDNA in Candida glabrata
    • DOI 10.1111/j.1567-1364.2006.00194.x
    • C. Westermeyer, and I.G. Macreadie Simvastatin reduces ergosterol levels, inhibits growth and causes loss of mtDNA in Candida glabrata FEMS Yeast Res 7 3 May 2007 436 441 [PubMed PMID: 17257373. Epub 2007/01/30. eng] (Pubitemid 46555514)
    • (2007) FEMS Yeast Research , vol.7 , Issue.3 , pp. 436-441
    • Westermeyer, C.1    Macreadie, I.G.2
  • 32
    • 37749013015 scopus 로고    scopus 로고
    • Biological consequences of statins in Candida species and possible implications for human health
    • [PubMed PMID: 18031260. Epub 2007/11/23. eng]
    • K. Wikhe, C. Westermeyer, and I.G. Macreadie Biological consequences of statins in Candida species and possible implications for human health Biochem Soc Trans 35 Pt 6 Dec 2007 1529 1532 [PubMed PMID: 18031260. Epub 2007/11/23. eng]
    • (2007) Biochem Soc Trans , vol.35 , Issue.PART 6 , pp. 1529-1532
    • Wikhe, K.1    Westermeyer, C.2    MacReadie, I.G.3
  • 34
    • 0036355070 scopus 로고    scopus 로고
    • Measuring oxidative mtDNA damage and repair using quantitative PCR
    • [PubMed PMID: 12013794. Epub 2002/05/17. eng]
    • J.H. Santos, B.S. Mandavilli, and B. Van Houten Measuring oxidative mtDNA damage and repair using quantitative PCR Methods Mol Biol 197 2002 159 176 [PubMed PMID: 12013794. Epub 2002/05/17. eng]
    • (2002) Methods Mol Biol , vol.197 , pp. 159-176
    • Santos, J.H.1    Mandavilli, B.S.2    Van Houten, B.3
  • 35
    • 84859061853 scopus 로고    scopus 로고
    • Blood mitochondrial DNA mutations in HIV-Infected women and their infants exposed to highly active antiretroviral therapy during pregnancy
    • [Pubmed PMID: 22436539]
    • M. Jitratkosol, B. Sattha, E. Maan, I. Gadawski, P. Harrigan, and J.C. Forbes Blood mitochondrial DNA mutations in HIV-Infected women and their infants exposed to highly active antiretroviral therapy during pregnancy AIDS 26 6 Mar 27 2012 675 683 [Pubmed PMID: 22436539]
    • (2012) AIDS , vol.26 , Issue.6 , pp. 675-683
    • Jitratkosol, M.1    Sattha, B.2    Maan, E.3    Gadawski, I.4    Harrigan, P.5    Forbes, J.C.6
  • 36
    • 10044232783 scopus 로고    scopus 로고
    • Could mitochondrial DNA quantitation be a surrogate marker for drug mitochondrial toxicity?
    • [PubMed PMID: 15595434. Epub 2004/12/15. eng]
    • C. de Mendoza, M. Sanchez-Conde, E. Ribera, P. Domingo, and V. Soriano Could mitochondrial DNA quantitation be a surrogate marker for drug mitochondrial toxicity? AIDS Rev 6 3 Jul-Sep 2004 169 180 [PubMed PMID: 15595434. Epub 2004/12/15. eng]
    • (2004) AIDS Rev , vol.6 , Issue.3 , pp. 169-180
    • De Mendoza, C.1    Sanchez-Conde, M.2    Ribera, E.3    Domingo, P.4    Soriano, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.