The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing

Journal of Pathology

Volumn 229, Issue 3, 2013, Pages 486-496

  Chen, Yu Ling ^a   Yuan, Ray Hwang ^b   Yang, Wan Ching ^a   Hsu, Hey Chi ^a   Jeng, Yung Ming ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

c Myc; hepatocellular carcinoma; Lin 41; microRNA

Indexed keywords

ALPHA FETOPROTEIN; ARGONAUTE 1 PROTEIN; ARGONAUTE 2 PROTEIN; HIGH MOBILITY GROUP A2 PROTEIN; LIN 41 LIGASE; MICRORNA; MICRORNA LET 7; SOMATOMEDIN C RECEPTOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GRADING; CANCER GROWTH; CANCER INHIBITION; CANCER RECURRENCE; CANCER STAGING; CANCER STEM CELL; CARCINOGENICITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CANCER; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LONG TERM SURVIVAL; MAJOR CLINICAL STUDY; MALE; MITOSIS INHIBITION; MOUSE; NONHUMAN; ONCOGENE; ONCOGENE C MYC; ONCOGENE LIN 28B; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA INTERFERENCE; TRANSACTIVATION; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ARGONAUTE PROTEINS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE PROGRESSION; EUKARYOTIC INITIATION FACTORS; FEMALE; GENE SILENCING; HUMANS; LIVER NEOPLASMS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED NOD; MICE, SCID; MICRORNAS; MIDDLE AGED; NEOPLASTIC STEM CELLS; YOUNG ADULT;

EID: 84872900635     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4130     Document Type: Article

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