-
1
-
-
0028817867
-
Drug-induced hepatotoxicity
-
Lee WM. Drug-induced hepatotoxicity. Med Prog 1995: 1118-1127.
-
(1995)
Med Prog
, pp. 1118-1127
-
-
Lee, W.M.1
-
2
-
-
17744385960
-
Forum: In vitro human tissue models in risk assessment: Report of a consensus-building workshop
-
MacGregor JT, Collins JM, Sugiyama Y, Tyson CA, Dean J, Smith L, Andersen M, Curren RD, Houston JB, Kadlubar FF, Kedderis GL, Krishnan K, Li AP, Parchment RE, Thummel K, Tomaszewski JE, Ulrich R, Vickers AEM, Wrighton SA. Forum: in vitro human tissue models in risk assessment: report of a consensus-building workshop. Toxicol Sci 2001; 59: 17-36.
-
(2001)
Toxicol Sci
, vol.59
, pp. 17-36
-
-
MacGregor, J.T.1
Collins, J.M.2
Sugiyama, Y.3
Tyson, C.A.4
Dean, J.5
Smith, L.6
Andersen, M.7
Curren, R.D.8
Houston, J.B.9
Kadlubar, F.F.10
Kedderis, G.L.11
Krishnan, K.12
Li, A.P.13
Parchment, R.E.14
Thummel, K.15
Tomaszewski, J.E.16
Ulrich, R.17
Vickers, A.E.M.18
Wrighton, S.A.19
-
3
-
-
0036163759
-
Forum: Mechanisms of hepatotoxicity
-
Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, Lemasters JJ. Forum: mechanisms of hepatotoxicity. Toxicol Sci 2002; 65: 166-176.
-
(2002)
Toxicol Sci
, vol.65
, pp. 166-176
-
-
Jaeschke, H.1
Gores, G.J.2
Cederbaum, A.I.3
Hinson, J.A.4
Pessayre, D.5
Lemasters, J.J.6
-
4
-
-
0031949067
-
Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins
-
Beckwith-Hall BM, Nicholson JK, Nicholls AW, Foxall PJD, Lindon JC, Connor SC, Abdi M, Connelly J, Holmes E. Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins. Chem Res Toxicol 1998; 11: 260-272.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 260-272
-
-
Beckwith-Hall, B.M.1
Nicholson, J.K.2
Nicholls, A.W.3
Foxall, P.J.D.4
Lindon, J.C.5
Connor, S.C.6
Abdi, M.7
Connelly, J.8
Holmes, E.9
-
5
-
-
0034861361
-
Metabonomic investigations into hydrazine toxicity in the rat
-
Nicholls AW, Holmes E, Lindon JC, Shockcor JP, Farrant RD, Haselden JN, Damment SJP, Waterfield CJ, Nicholson JK. Metabonomic investigations into hydrazine toxicity in the rat. Chem Res Toxicol 2001; 14: 975-987.
-
(2001)
Chem Res Toxicol
, vol.14
, pp. 975-987
-
-
Nicholls, A.W.1
Holmes, E.2
Lindon, J.C.3
Shockcor, J.P.4
Farrant, R.D.5
Haselden, J.N.6
Damment, S.J.P.7
Waterfield, C.J.8
Nicholson, J.K.9
-
7
-
-
0029907687
-
Changes in taurine as an indicator of hepatic dysfunction and biochemical perturbations
-
Timbrell JA, Waterfield CJ. Changes in taurine as an indicator of hepatic dysfunction and biochemical perturbations. Studies in vivo and in vitro. Adv Exp Med Biol 1996; 403: 233-245.
-
(1996)
Studies in vivo and in vitro. Adv Exp Med Biol
, vol.403
, pp. 233-245
-
-
Timbrell, J.A.1
Waterfield, C.J.2
-
8
-
-
0027161423
-
Investigation into the effects of various hepatotoxic compounds on urinary and liver taurine levels in rats
-
Waterfield CJ, Turton JA, Scales MD, Timbrell JA. Investigation into the effects of various hepatotoxic compounds on urinary and liver taurine levels in rats. Arch Toxicol 1993; 67: 244-254.
-
(1993)
Arch Toxicol
, vol.67
, pp. 244-254
-
-
Waterfield, C.J.1
Turton, J.A.2
Scales, M.D.3
Timbrell, J.A.4
-
10
-
-
0034775361
-
NMR and pattern recognition studies on the time-related metabolic effects of a-naphthylisothiocyanate on liver, urine, and plasma in the rat: An integrative metabonomic approach
-
Waters NJ, Holmes E, Williams A, Waterfield CJ, Farrant RD, Nicholson JK. NMR and pattern recognition studies on the time-related metabolic effects of a-naphthylisothiocyanate on liver, urine, and plasma in the rat: an integrative metabonomic approach. Chem Res Toxicol 2001; 14: 1401-1412.
-
(2001)
Chem Res Toxicol
, vol.14
, pp. 1401-1412
-
-
Waters, N.J.1
Holmes, E.2
Williams, A.3
Waterfield, C.J.4
Farrant, R.D.5
Nicholson, J.K.6
-
11
-
-
0033795182
-
Metabonomics: Evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants
-
Robertson DG, Reily MD, Sigler RE, Wells DF, Paterson DA, Braden TK. Metabonomics: evaluation of nuclear magnetic resonance (NMR) and pattern recognition technology for rapid in vivo screening of liver and kidney toxicants. Toxicol Sci 2000; 57: 326-337.
-
(2000)
Toxicol Sci
, vol.57
, pp. 326-337
-
-
Robertson, D.G.1
Reily, M.D.2
Sigler, R.E.3
Wells, D.F.4
Paterson, D.A.5
Braden, T.K.6
-
12
-
-
0026744665
-
Proton NMR spectroscopic studies on the metabolism and biochemical effects of hydrazine in vivo
-
Sanins SM, Timbrell JA, Elcombe C, Nicholson JK. Proton NMR spectroscopic studies on the metabolism and biochemical effects of hydrazine in vivo. Arch Toxicol 1992; 66: 489-495.
-
(1992)
Arch Toxicol
, vol.66
, pp. 489-495
-
-
Sanins, S.M.1
Timbrell, J.A.2
Elcombe, C.3
Nicholson, J.K.4
-
13
-
-
77957168192
-
High-resolution proton-NMR studies of metabolism and effects of hydrazine in rat
-
Sanins SM, Timbrell JA, Nicholson JK. High-resolution proton-NMR studies of metabolism and effects of hydrazine in rat. Hum Toxicol (Suppl) 1986; 5: 123.
-
(1986)
Hum Toxicol (Suppl)
, vol.5
, pp. 123
-
-
Sanins, S.M.1
Timbrell, J.A.2
Nicholson, J.K.3
-
14
-
-
0019184171
-
Sterospecificity of the gliotoxic and anti-neurotoxic actions of alpha-aminoadipate
-
Olney JW, de Gubareff T, Collins JF. Sterospecificity of the gliotoxic and anti-neurotoxic actions of alpha-aminoadipate. Neurosci Lett 1980; 19: 277-282.
-
(1980)
Neurosci Lett
, vol.19
, pp. 277-282
-
-
Olney, J.W.1
de Gubareff, T.2
Collins, J.F.3
-
15
-
-
0031057309
-
Cationic amphiphilic drug-induced phospholipidosis
-
Halliwell WH. Cationic amphiphilic drug-induced phospholipidosis. Toxicol Pathol 1997; 25: 53-60.
-
(1997)
Toxicol Pathol
, vol.25
, pp. 53-60
-
-
Halliwell, W.H.1
-
16
-
-
0025572278
-
Cationic amphiphilic drugs and phospholipid storage disorder
-
Kodavanti UP, Mehendale HM. Cationic amphiphilic drugs and phospholipid storage disorder. Pharmacol Rev 1990; 42: 327-354.
-
(1990)
Pharmacol Rev
, vol.42
, pp. 327-354
-
-
Kodavanti, U.P.1
Mehendale, H.M.2
-
17
-
-
0034530607
-
A metabonomic approach to the investigation of drug-induced phospholipidosis: An NMR spectroscopy and pattern recognition study
-
Nicholls AW, Nicholson JK, Haselden JN, Waterfield CJ. A metabonomic approach to the investigation of drug-induced phospholipidosis: an NMR spectroscopy and pattern recognition study. Biomarkers 2000; 5: 410-423.
-
(2000)
Biomarkers
, vol.5
, pp. 410-423
-
-
Nicholls, A.W.1
Nicholson, J.K.2
Haselden, J.N.3
Waterfield, C.J.4
-
18
-
-
0000981799
-
Detection of in vivo biomarkers of phospholipidosis using NMR-based metabonomic approaches
-
Espina JR, Shockcor JP, Herron WJ, Car BD, Contel NR, Ciaccio PJ, Lindon JC, Holmes E, Nicholson JK. Detection of in vivo biomarkers of phospholipidosis using NMR-based metabonomic approaches. Magn Reson Chem 2001; 39: 559-565.
-
(2001)
Magn Reson Chem
, vol.39
, pp. 559-565
-
-
Espina, J.R.1
Shockcor, J.P.2
Herron, W.J.3
Car, B.D.4
Contel, N.R.5
Ciaccio, P.J.6
Lindon, J.C.7
Holmes, E.8
Nicholson, J.K.9
-
20
-
-
0034660325
-
1H NMR spectroscopy of intact liver and kidney: Optimization of sample preparation procedures and biochemical stability of tissue during spectral acquisition
-
1H NMR spectroscopy of intact liver and kidney: optimization of sample preparation procedures and biochemical stability of tissue during spectral acquisition. Anal Biochem 2000; 282: 16-23.
-
(2000)
Anal Biochem
, vol.282
, pp. 16-23
-
-
Waters, N.J.1
Garrod, S.2
Farrant, R.D.3
Haselden, J.N.4
Connor, S.C.5
Connelly, J.6
Lindon, J.C.7
Holmes, E.8
Nicholson, J.K.9
-
21
-
-
0036639485
-
NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate
-
Waters NJ, Holmes E, Waterfield CJ, Farrant RD, Nicholson JK. NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate. Biochem Pharmacol 2002; 64: 67-77.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 67-77
-
-
Waters, N.J.1
Holmes, E.2
Waterfield, C.J.3
Farrant, R.D.4
Nicholson, J.K.5
-
23
-
-
0034130232
-
Chemometric models for toxicity classification based on NMR spectra of biofluids
-
Holmes E, Nicholls AW, Lindon JC, Connor SC, Connelly JC, Haselden JN, Damment SJP, Spraul M, Neidig P, Nicholson JK. Chemometric models for toxicity classification based on NMR spectra of biofluids. Chem Res Toxicol 2000; 13: 471-478.
-
(2000)
Chem Res Toxicol
, vol.13
, pp. 471-478
-
-
Holmes, E.1
Nicholls, A.W.2
Lindon, J.C.3
Connor, S.C.4
Connelly, J.C.5
Haselden, J.N.6
Damment, S.J.P.7
Spraul, M.8
Neidig, P.9
Nicholson, J.K.10
-
24
-
-
7344256122
-
1H NMR spectroscopy of urine combined with pattern recognition
-
1H NMR spectroscopy of urine combined with pattern recognition. NMR Biomed 1998; 11: 235-244.
-
(1998)
NMR Biomed
, vol.11
, pp. 235-244
-
-
Holmes, E.1
Nicholls, A.W.2
Lindon, J.C.3
Ramos, S.4
Spraul, M.5
Neidig, P.6
Connor, S.C.7
Connelly, J.8
Damment, S.J.P.9
Haselden, J.10
Nicholson, J.K.11
-
25
-
-
0035107971
-
Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks
-
Holmes E, Nicholson JK, Tranter G. Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks. Chem Res Toxicol 2001; 14: 182-191.
-
(2001)
Chem Res Toxicol
, vol.14
, pp. 182-191
-
-
Holmes, E.1
Nicholson, J.K.2
Tranter, G.3
-
26
-
-
0036174751
-
Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data
-
Azmi J, Griffin JL, Antti H, Shore RF, Johansson E, Nicholson JK, Holmes E. Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data. Analyst 2002; 127: 271-276.
-
(2002)
Analyst
, vol.127
, pp. 271-276
-
-
Azmi, J.1
Griffin, J.L.2
Antti, H.3
Shore, R.F.4
Johansson, E.5
Nicholson, J.K.6
Holmes, E.7
-
28
-
-
0034368580
-
Metabonomics: Metabolic processes studied by NMR spectroscopy of biofluids
-
Lindon JC, Nicholson JK, Holmes E, Everett JR. Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts Magn Reson 2000; 12(5): 289-320.
-
(2000)
Concepts Magn Reson
, vol.12
, Issue.5
, pp. 289-320
-
-
Lindon, J.C.1
Nicholson, J.K.2
Holmes, E.3
Everett, J.R.4
-
29
-
-
0027426219
-
Proton nuclear magnetic resonance spectroscopy of urine and plasma in renal transplantation followup
-
Le Moyec L, Pruna A, Eugene M, Bedrossian J, Idatte JM, Huneau JF, Tomé D. Proton nuclear magnetic resonance spectroscopy of urine and plasma in renal transplantation followup. Nephron 1993; 65: 433-439.
-
(1993)
Nephron
, vol.65
, pp. 433-439
-
-
Le Moyec, L.1
Pruna, A.2
Eugene, M.3
Bedrossian, J.4
Idatte, J.M.5
Huneau, J.F.6
Tomé, D.7
-
32
-
-
0022296430
-
Two-dimensional proton nuclear magnetic resonance '‘maps’' of acetaminophen metabolites in human urine
-
Bales JR, Nicholson JK, Sadler PJ. Two-dimensional proton nuclear magnetic resonance '‘maps’' of acetaminophen metabolites in human urine. Clin Chem 1985; 31: 757-762.
-
(1985)
Clin Chem
, vol.31
, pp. 757-762
-
-
Bales, J.R.1
Nicholson, J.K.2
Sadler, P.J.3
-
33
-
-
0003550344
-
Proton NMR spectroscopy of bile as a marker of liver function in liver-transplant patients
-
Powell JJ, Gartland KPR, Lombard M, Sallie R, Nicholson JK, Thompson RPH. Proton NMR spectroscopy of bile as a marker of liver function in liver-transplant patients. Clin Sci 1990; 78: 13.
-
(1990)
Clin Sci
, vol.78
, pp. 13
-
-
Powell, J.J.1
Gartland, K.P.R.2
Lombard, M.3
Sallie, R.4
Nicholson, J.K.5
Thompson, R.P.H.6
-
34
-
-
0024946615
-
High resolution proton magnetic resonance spectroscopy of biological fluids
-
Nicholson JK, Wilson ID. High resolution proton magnetic resonance spectroscopy of biological fluids. Prog NMR Spectrosc 1989; 21: 444-501.
-
(1989)
Prog NMR Spectrosc
, vol.21
, pp. 444-501
-
-
Nicholson, J.K.1
Wilson, I.D.2
-
35
-
-
0022385084
-
Biochemical mechanisms of nephrotoxicity
-
Hook JB, Smith JH. Biochemical mechanisms of nephrotoxicity. Transplantation Proceedings 17 (supplement 1): 41-50, 1985.
-
(1985)
Transplantation Proceedings
, vol.17
, pp. 41-50
-
-
Hook, J.B.1
Smith, J.H.2
-
37
-
-
0038854471
-
Toxic responses of the kidney
-
Klaassen CD, Amdur MO, Doull J, eds, New York: Macmillan
-
Hook JB, Hewit WR. Toxic responses of the kidney. In: Klaassen CD, Amdur MO, Doull J, eds. Toxicology: The Basic Science of Poisons. New York: Macmillan, 1986: 310-329.
-
(1986)
Toxicology: The Basic Science of Poisons
, pp. 310-329
-
-
Hook, J.B.1
Hewit, W.R.2
-
38
-
-
0006568776
-
Renal methods in toxicology
-
Hayes WA, ed, New York: Raven Press
-
Berndt WO. Renal methods in toxicology. In: Hayes WA, ed. Principles and Methods of Toxicology. New York: Raven Press, 1982: 447-474.
-
(1982)
Principles and Methods of Toxicology
, pp. 447-474
-
-
Berndt, W.O.1
-
39
-
-
0344144576
-
Urinary enzymes, proteinuria and renal function tests in the assessment of nephrotoxicity in the rat
-
Bach PH, Lock EA, eds, Chichester, U.K.: Wiley
-
Halman J, Fowler JSL, Price RG. Urinary enzymes, proteinuria and renal function tests in the assessment of nephrotoxicity in the rat. In: Bach PH, Lock EA, eds. Renal Heterogeneity and Target Cell Toxicity. Chichester, U.K.: Wiley, 1985: 295-298.
-
(1985)
Renal Heterogeneity and Target Cell Toxicity
, pp. 295-298
-
-
Halman, J.1
Fowler, J.S.L.2
Price, R.G.3
-
40
-
-
0024580448
-
Investigation into the biochemical effects of region-specific nephrotoxins
-
Gartland KPR, Bonner FW, Nicholson JK. Investigation into the biochemical effects of region-specific nephrotoxins. Mol Pharmacol 1989; 35: 242-250.
-
(1989)
Mol Pharmacol
, vol.35
, pp. 242-250
-
-
Gartland, K.P.R.1
Bonner, F.W.2
Nicholson, J.K.3
-
41
-
-
0027972888
-
Studies on the comparative toxicity of S-(1, 2-dichlorovinyl)-l-cysteine and 1, 1, 2-triflchloro-3, 3, 3-fluoro-1-propene in the Fischer 344 rat
-
Anthony ML, Beddell CR, Lindon JC, Nicholson JK. Studies on the comparative toxicity of S-(1, 2-dichlorovinyl)-l-cysteine and 1, 1, 2-triflchloro-3, 3, 3-fluoro-1-propene in the Fischer 344 rat. Arch Toxicol 1994; 69: 99-110.
-
(1994)
Arch Toxicol
, vol.69
, pp. 99-110
-
-
Anthony, M.L.1
Beddell, C.R.2
Lindon, J.C.3
Nicholson, J.K.4
-
42
-
-
0032517858
-
The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine
-
Holmes E, Nicholson JK, Nicholls AW, Lindon JC, Connor SC, Polley S, Connelly J. The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine. Chemometrics Intell Lab Syst 1998; 44: 245-255.
-
(1998)
Chemometrics Intell Lab Syst
, vol.44
, pp. 245-255
-
-
Holmes, E.1
Nicholson, J.K.2
Nicholls, A.W.3
Lindon, J.C.4
Connor, S.C.5
Polley, S.6
Connelly, J.7
-
45
-
-
0034726045
-
The initial pathogenesis of cadmium induced renal toxicity
-
Griffin JL, Walker LA, Troke J, Osborn D, Shore RF, Nicholson JK. The initial pathogenesis of cadmium induced renal toxicity. FEBS Lett 2000; 478: 147-150.
-
(2000)
FEBS Lett
, vol.478
, pp. 147-150
-
-
Griffin, J.L.1
Walker, L.A.2
Troke, J.3
Osborn, D.4
Shore, R.F.5
Nicholson, J.K.6
-
46
-
-
48749147628
-
Renal effects of antipyretic analgesics
-
Nov 14
-
Nanra RS. Renal effects of antipyretic analgesics. Am J Med 1983; Nov 14: 70-80.
-
(1983)
Am J Med
, pp. 70-80
-
-
Nanra, R.S.1
-
47
-
-
0023971143
-
Analgesic-induced papillary necrosis
-
Sabatini S. Analgesic-induced papillary necrosis. Semin Nephrol 1988; 8(1): 41-54.
-
(1988)
Semin Nephrol
, vol.8
, Issue.1
, pp. 41-54
-
-
Sabatini, S.1
-
48
-
-
0018127792
-
Pharmacological mechanisms of analgesic nephropathy
-
Shelley JH. Pharmacological mechanisms of analgesic nephropathy. Kidney Int 1978; 13: 15-26.
-
(1978)
Kidney Int
, vol.13
, pp. 15-26
-
-
Shelley, J.H.1
-
49
-
-
0029565805
-
Comparative studies on the nephrotoxicity of 2-bromoethanamine hydrobromide in the Fischer 344 rat and the multimammate desert mouse (Mastomys natalensis)
-
Holmes E, Bonner FW, Nicholson JK. Comparative studies on the nephrotoxicity of 2-bromoethanamine hydrobromide in the Fischer 344 rat and the multimammate desert mouse (Mastomys natalensis). Arch Toxicol 1995; 70: 89-95.
-
(1995)
Arch Toxicol
, vol.70
, pp. 89-95
-
-
Holmes, E.1
Bonner, F.W.2
Nicholson, J.K.3
-
50
-
-
0025954351
-
Altered renal fibronectin excretion in early adriamycin nephrosis of rats
-
Soose M, Gwinner W, Grotkamp J, Hansemann W, Stolte H. Altered renal fibronectin excretion in early adriamycin nephrosis of rats. J Pharm Exp Ther 1991; 257(1): 493-499.
-
(1991)
J Pharm Exp Ther
, vol.257
, Issue.1
, pp. 493-499
-
-
Soose, M.1
Gwinner, W.2
Grotkamp, J.3
Hansemann, W.4
Stolte, H.5
-
51
-
-
0022252916
-
Adriamycin-induced chronic proteinuria: A structural and functional study
-
O’Donnell MP, Michels L, Kasiske B, Raij L, Keane WF. Adriamycin-induced chronic proteinuria: a structural and functional study. J Lab Clin Med 1985; 106(1): 62-67.
-
(1985)
J Lab Clin Med
, vol.106
, Issue.1
, pp. 62-67
-
-
O’Donnell, M.P.1
Michels, L.2
Kasiske, B.3
Raij, L.4
Keane, W.F.5
-
52
-
-
0021996130
-
Mesangial function and glomerular sclerosis in rats with aminonucleoside nephrosis
-
Grond J, Koudstaal J, Elema JD. Mesangial function and glomerular sclerosis in rats with aminonucleoside nephrosis. Kidney Int 1985; 27(2): 405-410.
-
(1985)
Kidney Int
, vol.27
, Issue.2
, pp. 405-410
-
-
Grond, J.1
Koudstaal, J.2
Elema, J.D.3
-
53
-
-
0022519363
-
Drug associated glomerulopathies
-
Hill GS. Drug associated glomerulopathies. Toxicol Pathol 1986; 14: 37-44.
-
(1986)
Toxicol Pathol
, vol.14
, pp. 37-44
-
-
Hill, G.S.1
-
54
-
-
0033434082
-
An integrated proteomic approach to studying glomerular nephrotoxicity
-
Cutler P, Bell DJ, Birrell HC, Connelly JC, Connor SC, Holmes E, Mitchell BC, Monte SY, Neville BA, Pickford R, Polley S, Schneider K, Skehel JM. An integrated proteomic approach to studying glomerular nephrotoxicity. Electrophoresis 1999; 20(18): 3647-3658.
-
(1999)
Electrophoresis
, vol.20
, Issue.18
, pp. 3647-3658
-
-
Cutler, P.1
Bell, D.J.2
Birrell, H.C.3
Connelly, J.C.4
Connor, S.C.5
Holmes, E.6
Mitchell, B.C.7
Monte, S.Y.8
Neville, B.A.9
Pickford, R.10
Polley, S.11
Schneider, K.12
Skehel, J.M.13
-
55
-
-
0015576741
-
Strain differences in metabolism and susceptibility to the nephrotoxic effects of methoxyfluorane in rats
-
Mazze RI, Cousins MJ, Kosek JC. Strain differences in metabolism and susceptibility to the nephrotoxic effects of methoxyfluorane in rats. J Pharmacol Exp Ther 1973; 184: 481-488.
-
(1973)
J Pharmacol Exp Ther
, vol.184
, pp. 481-488
-
-
Mazze, R.I.1
Cousins, M.J.2
Kosek, J.C.3
-
56
-
-
0020695965
-
A new reproducible experimental model of analgesic nephropathy
-
Henry MA, Sweet RS, Tange JD. A new reproducible experimental model of analgesic nephropathy. J Pathol 1983; 139: 23-32.
-
(1983)
J Pathol
, vol.139
, pp. 23-32
-
-
Henry, M.A.1
Sweet, R.S.2
Tange, J.D.3
-
57
-
-
3042619232
-
Comparative biochemical effects of low doses of mercury II chloride in the F344 rat and the multimammate mouse (Mastomys natalensis)
-
Holmes E, Bonner FW, Nicholson JK. Comparative biochemical effects of low doses of mercury II chloride in the F344 rat and the multimammate mouse (Mastomys natalensis). Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1996; 114(1): 7-15.
-
(1996)
Comp Biochem Physiol C Pharmacol Toxicol Endocrinol
, vol.114
, Issue.1
, pp. 7-15
-
-
Holmes, E.1
Bonner, F.W.2
Nicholson, J.K.3
-
58
-
-
0030612030
-
1H NMR spectroscopic and histopathological studies on propyleneimine-induced renal papillary necrosis in the rat the multimammate desert mouse (Mastomys natalensis)
-
1H NMR spectroscopic and histopathological studies on propyleneimine-induced renal papillary necrosis in the rat the multimammate desert mouse (Mastomys natalensis). Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1997; 116(2): 125-134.
-
(1997)
Comp Biochem Physiol C Pharmacol Toxicol Endocrinol
, vol.116
, Issue.2
, pp. 125-134
-
-
Holmes, E.1
Bonner, F.W.2
Nicholson, J.K.3
-
59
-
-
0025287178
-
Acute cadmium chloride-induced renal toxicity in the Syrian hamster
-
Rehm S, Waalkes MP. Acute cadmium chloride-induced renal toxicity in the Syrian hamster. Toxicol Appl Pharmacol 1990; 104(1): 94-105.
-
(1990)
Toxicol Appl Pharmacol
, vol.104
, Issue.1
, pp. 94-105
-
-
Rehm, S.1
Waalkes, M.P.2
-
60
-
-
0025285388
-
Diphenylamine-induced renal papillary necrosis and necrosis of the pars recta in laboratory rodents
-
Lenz SD, Carlton WW. Diphenylamine-induced renal papillary necrosis and necrosis of the pars recta in laboratory rodents. Vet Pathol 1990; 27(3): 171-178.
-
(1990)
Vet Pathol
, vol.27
, Issue.3
, pp. 171-178
-
-
Lenz, S.D.1
Carlton, W.W.2
-
61
-
-
0036917875
-
Chemometric contributions to the evolution of metabonomics: Mathematical solutions to characterising and interpreting complex biological NMR spectra
-
Holmes E, Antti H. Chemometric contributions to the evolution of metabonomics: mathematical solutions to characterising and interpreting complex biological NMR spectra. Analyst 2002; 127: 549-1557.
-
(2002)
Analyst
, vol.127
, pp. 549-1557
-
-
Holmes, E.1
Antti, H.2
-
62
-
-
0027052705
-
Nuclear magnetic resonance spectroscopy and pattern recognition analysis of the biochemical processes associated with the progression of and recovery from nephrotoxic lesions in the rat induced by mercury (II) chloride and 2-bromoethanamine
-
Holmes E, Bonner FW, Sweatman BC, Lindon JC, Beddell CR, Rahr E, Nicholson JK. Nuclear magnetic resonance spectroscopy and pattern recognition analysis of the biochemical processes associated with the progression of and recovery from nephrotoxic lesions in the rat induced by mercury (II) chloride and 2-bromoethanamine. Mol Pharmacol 1992; 42: 922-930.
-
(1992)
Mol Pharmacol
, vol.42
, pp. 922-930
-
-
Holmes, E.1
Bonner, F.W.2
Sweatman, B.C.3
Lindon, J.C.4
Beddell, C.R.5
Rahr, E.6
Nicholson, J.K.7
-
63
-
-
0026611216
-
1H NMR spectroscopy as a means of monitoring nephrotoxicity as exemplified by studies with cephaloridine
-
Murgatroyd LB, Pickford RJ, Smith IK, Wilson ID, Middleton BJ. 1H NMR spectroscopy as a means of monitoring nephrotoxicity as exemplified by studies with cephaloridine. Hum Exp Toxicol 1992; 11(1): 35-41.
-
(1992)
Hum Exp Toxicol
, vol.11
, Issue.1
, pp. 35-41
-
-
Murgatroyd, L.B.1
Pickford, R.J.2
Smith, I.K.3
Wilson, I.D.4
Middleton, B.J.5
-
64
-
-
0025609215
-
Proton NMR studies on the effects of uranyl nitrate on the biochemical composition of rat urine and plasma
-
Gartland KP, Anthony ML, Beddell CR, Lindon JC, Nicholson JK. Proton NMR studies on the effects of uranyl nitrate on the biochemical composition of rat urine and plasma. J Pharm Biomed Anal 1990; 8(8-12): 951-954.
-
(1990)
J Pharm Biomed Anal
, vol.8
, Issue.8-12
, pp. 951-954
-
-
Gartland, K.P.1
Anthony, M.L.2
Beddell, C.R.3
Lindon, J.C.4
Nicholson, J.K.5
-
65
-
-
0029814551
-
Characterization of coronary arterial lesions in the dog following administration of SKandF 95654, a phosphodiesterase III inhibitor
-
Joseph EC, Jones HB, Kerns WD. Characterization of coronary arterial lesions in the dog following administration of SKandF 95654, a phosphodiesterase III inhibitor. Toxicol Pathol 1996; 24: 429-435.
-
(1996)
Toxicol Pathol
, vol.24
, pp. 429-435
-
-
Joseph, E.C.1
Jones, H.B.2
Kerns, W.D.3
-
66
-
-
0030053450
-
The toxicity of repeated exposures to rolipram, a type IV phosphodiesterase inhibitor, in rats
-
Larson JL, Pino MV, Geiger LE, Simeone CR. The toxicity of repeated exposures to rolipram, a type IV phosphodiesterase inhibitor, in rats. Pharmacol Toxicol 1996; 78: 44-49.
-
(1996)
Pharmacol Toxicol
, vol.78
, pp. 44-49
-
-
Larson, J.L.1
Pino, M.V.2
Geiger, L.E.3
Simeone, C.R.4
-
67
-
-
0032957421
-
Coronary arteriopathy in monkeys following administration of CI-1020, an endothelin A receptor antagonist
-
Albassam MA, Metz AL, Gragtmans NJ, King LM, Macallum GE, Hallak H, McGuire EJ. Coronary arteriopathy in monkeys following administration of CI-1020, an endothelin A receptor antagonist. Toxicol Pathol 1999; 27: 156-164.
-
(1999)
Toxicol Pathol
, vol.27
, pp. 156-164
-
-
Albassam, M.A.1
Metz, A.L.2
Gragtmans, N.J.3
King, L.M.4
Macallum, G.E.5
Hallak, H.6
McGuire, E.J.7
-
68
-
-
0034956762
-
Studies on coronary arteriopathy in dogs following administration of CI-1020, an endothelin A receptor antagonist
-
Albassam MA, Metz AL, Potoczak RE, Gallagher KP, Haleen S, Hallak H, McGuire EJ. Studies on coronary arteriopathy in dogs following administration of CI-1020, an endothelin A receptor antagonist. Toxicol Pathol 2001; 29: 277-284.
-
(2001)
Toxicol Pathol
, vol.29
, pp. 277-284
-
-
Albassam, M.A.1
Metz, A.L.2
Potoczak, R.E.3
Gallagher, K.P.4
Haleen, S.5
Hallak, H.6
McGuire, E.J.7
-
69
-
-
0025916292
-
Acute cardiovascular toxicity induced by an adenosine agonist-antihypertensive in beagles
-
Metz AL, Dominick MA, Suchanek G, Gough AW. Acute cardiovascular toxicity induced by an adenosine agonist-antihypertensive in beagles. Toxicol Pathol 1991; 19: 98-107.
-
(1991)
Toxicol Pathol
, vol.19
, pp. 98-107
-
-
Metz, A.L.1
Dominick, M.A.2
Suchanek, G.3
Gough, A.W.4
-
70
-
-
0024554323
-
Pathogenesis of arterial lesions induced by dopaminergic compounds in the rat
-
Kerns WD, Arena E, Macia RA, Bugelski PJ, Matthews WD, Morgan DG. Pathogenesis of arterial lesions induced by dopaminergic compounds in the rat. Toxicol Pathol 1989; 17: 203-213.
-
(1989)
Toxicol Pathol
, vol.17
, pp. 203-213
-
-
Kerns, W.D.1
Arena, E.2
Macia, R.A.3
Bugelski, P.J.4
Matthews, W.D.5
Morgan, D.G.6
-
71
-
-
0029081582
-
The pharmacologic basis of the cardiovascular toxicity of minoxidil in the dog
-
Mesfin GM, Robinson FG, Higgins MJ, Zhong WZ, DuCharme DW. The pharmacologic basis of the cardiovascular toxicity of minoxidil in the dog. Toxicol Pathol 1995; 23: 498-506.
-
(1995)
Toxicol Pathol
, vol.23
, pp. 498-506
-
-
Mesfin, G.M.1
Robinson, F.G.2
Higgins, M.J.3
Zhong, W.Z.4
DuCharme, D.W.5
-
73
-
-
4243746458
-
Preclinical toxicity studies of the phosphodiesterase IV inhibitor CI-1018 in rats
-
Dethloff LA, Pegg DG, Metz AL. Preclinical toxicity studies of the phosphodiesterase IV inhibitor CI-1018 in rats. Toxicol Sci 1999; 48(1S): 1502a.
-
(1999)
Toxicol Sci
, vol.48
, Issue.1
, pp. 1502
-
-
Dethloff, L.A.1
Pegg, D.G.2
Metz, A.L.3
-
74
-
-
0036406930
-
Effect of dexamethasone on the metabonomics profile associated with phosphodiesterase inhibitor-induced mesenteric vascular lesions in rats
-
Slim RM, Robertson DG, Albassam M, Reily MD, Robosky L, Dethloff LA. Effect of dexamethasone on the metabonomics profile associated with phosphodiesterase inhibitor-induced mesenteric vascular lesions in rats. Toxicol Appl Pharmacol 2002; 183: 108-116.
-
(2002)
Toxicol Appl Pharmacol
, vol.183
, pp. 108-116
-
-
Slim, R.M.1
Robertson, D.G.2
Albassam, M.3
Reily, M.D.4
Robosky, L.5
Dethloff, L.A.6
-
75
-
-
0034738997
-
Pathogenic principles in giant cell arteritis
-
Weyand CM, Goronzy JJ. Pathogenic principles in giant cell arteritis. Int J Cardiol 2000; 75: S9-S19.
-
(2000)
Int J Cardiol
, vol.75
, pp. S9-S19
-
-
Weyand, C.M.1
Goronzy, J.J.2
-
76
-
-
0035667990
-
Elevated serum levels of macrophage colonystimulating factor in patients with Kawasaki disease complicated by cardiac lesions
-
Igarashi H, Hatake K, Shiraishi H, Samada K, Tomizuka H, Momoi MY. Elevated serum levels of macrophage colonystimulating factor in patients with Kawasaki disease complicated by cardiac lesions. Clin Exp Rheumatol 2001; 19: 751-756.
-
(2001)
Clin Exp Rheumatol
, vol.19
, pp. 751-756
-
-
Igarashi, H.1
Hatake, K.2
Shiraishi, H.3
Samada, K.4
Tomizuka, H.5
Momoi, M.Y.6
-
77
-
-
0035166821
-
Drug-induced vasculitis
-
Merkel, PA. Drug-induced vasculitis. Rheum Dis Clin North Am 2001; 27: 849-862.
-
(2001)
Rheum Dis Clin North Am
, vol.27
, pp. 849-862
-
-
Merkel, P.A.1
-
78
-
-
85134967020
-
Metabonomic assessment of drug-induced vasculitis in rats
-
Robertson DG, Reily MD, Albassam M, Dethloff LA, Wells DF, Braden TK. Metabonomic assessment of drug-induced vasculitis in rats. Toxicol Sci 2001; 60(1S): 375.
-
(2001)
Toxicol Sci
, vol.60
, Issue.1
, pp. 375
-
-
Robertson, D.G.1
Reily, M.D.2
Albassam, M.3
Dethloff, L.A.4
Wells, D.F.5
Braden, T.K.6
|