A Novel Interaction between hScrib and PP1γ Downregulates ERK Signaling and Suppresses Oncogene-Induced Cell Transformation

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Nagasaka, Kazunori ^a   Seiki, Takayuki ^a   Yamashita, Aki ^a   Massimi, Paola ^b   Subbaiah, Vanitha Krishna ^b   Thomas, Miranda ^b   Kranjec, Christian ^b   Kawana, Kei ^a   Nakagawa, Shunsuke ^c   Yano, Tetsu ^a   Taketani, Yuji ^a   Fujii, Tomoyuki ^a   Kozuma, Shiro ^a   Banks, Lawrence ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^c TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN HSCRIB; PROTEIN PHOSPHATASE 1 GAMMA; REGULATOR PROTEIN; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; GENE REPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; NONHUMAN; ONCOGENE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT;

AMINO ACID SEQUENCE; BLOTTING, WESTERN; CELL TRANSFORMATION, NEOPLASTIC; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; ONCOGENES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PHOSPHATASE 1; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TUMOR SUPPRESSOR PROTEINS;

RODENTIA;

EID: 84872862228     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053752     Document Type: Article

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