Computational Screening of the Human TF-Glycome Provides a Structural Definition for the Specificity of Anti-Tumor Antibody JAA-F11

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Tessier, Matthew B ^a   Grant, Oliver C ^b   Heimburg Molinaro, Jamie ^c,d   Smith, David ^d   Jadey, Snehal ^c   Gulick, Andrew M ^c   Glushka, John ^a   Deutscher, Susan L ^e   Rittenhouse Olson, Kate ^c   Woods, Robert J ^a,b  

^a UNIVERSITY OF GEORGIA   (United States)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^c UNIVERSITY AT BUFFALO   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCAN DERIVATIVE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY JAA F11; THOMSEN FRIEDENREICH ANTIGEN; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; ANTIBODY STRUCTURE; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CARBOHYDRATE ANALYSIS; COMPUTATIONAL CARBOHYDRATE GRAFTING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; INTERMETHOD COMPARISON; MOLECULAR LIBRARY; STATISTICAL CONCEPTS; THREE DIMENSIONAL IMAGING; VIRTUAL REALITY;

ANTIBODIES, NEOPLASM; ANTIBODY SPECIFICITY; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CARBOHYDRATE CONFORMATION; CRYSTALLOGRAPHY, X-RAY; DISACCHARIDES; HUMANS; IMMUNOGLOBULIN G; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DOCKING SIMULATION; MUCINS; POLYSACCHARIDES; PROTEIN BINDING; SMALL MOLECULE LIBRARIES; USER-COMPUTER INTERFACE;

EID: 84872839664     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054874     Document Type: Article

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