Epigallocatechin-3-gallate and penta-O-galloyl-β-d-glucose inhibit protein phosphatase-1

FEBS Journal

Volumn 280, Issue 2, 2013, Pages 612-626

  Kiss, Andrea ^a,b   Bécsi, Bálint ^a   Kolozsvári, Bernadett ^a   Komáromi, István ^b   Kövér, Katalin E ^c   Erdodi, Ferenc ^a,b  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF DEBRECEN   (Hungary)

^c UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

green tea and tannin polyphenols; molecular modeling; NMR saturation transfer difference; Ser Thr specific protein phosphatase 1 and protein phosphatase 2A; surface plasmon resonance

Indexed keywords

CATECHOL DERIVATIVE; EPIGALLOCATECHIN GALLATE; FUNCTIONAL GROUP; GALLOYL GROUP; GLUCOSE PENTAGALLATE; HYDROXYL GROUP; MICROCYSTIN LR; OKADAIC ACID; OXO GROUP; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 1 CATALYTIC SUBUNIT; PHOSPHOPROTEIN PHOSPHATASE 2A; PHOSPHOPROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT; POLYPHENOL; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; BIOCATALYSIS; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME STRUCTURE; FEMALE; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROPHOBICITY; IC 50; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN INTERACTION; STRUCTURE ANALYSIS; SURFACE PLASMON RESONANCE;

CATECHIN; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HELA CELLS; HUMANS; HYDROLYZABLE TANNINS; ISOENZYMES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2; PROTEIN STRUCTURE, TERTIARY; SURFACE PLASMON RESONANCE; TEA;

EID: 84872779361     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08498.x     Document Type: Article

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