Peroxisome proliferator-activated receptor α positively regulates complement C3 expression but inhibits tumor necrosis factor-mediated activation of C3 gene in mammalian hepatic-derived cells

Journal of Biological Chemistry

Volumn 288, Issue 3, 2013, Pages 1726-1738

  Mogilenko, Denis A ^a   Kudriavtsev, Igor V ^a   Shavva, Vladimir S ^a   Dizhe, Ella B ^a   Vilenskaya, Ekaterina G ^a   Efremov, Alexander M ^a,b   Perevozchikov, Andrej P ^a   Orlov, Sergey V ^a  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT SYSTEMS; HEPATOCYTES; HEPG2 CELLS; HUMAN HEPATOMAS; IN-CONTROL; IN-VITRO; MOUSE LIVER; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PROTEIN CONTENTS; PROTEIN SECRETION; SIGNALING PATHWAYS; TUMOR NECROSIS; UP-REGULATION;

CELLS; CYTOLOGY; GENE EXPRESSION; MAMMALS; PATHOLOGY; PHYSIOLOGY;

GENE EXPRESSION REGULATION;

COMPLEMENT COMPONENT C3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; ARTICLE; C3 GENE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME ACTIVATION; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; MALE; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; COMPLEMENT C3; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HEPATOCYTES; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MALE; MAP KINASE KINASE 1; MAP KINASE KINASE 2; MICE; MICE, INBRED C57BL; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEROXISOME PROLIFERATORS; PPAR ALPHA; PROTEIN BINDING; PYRIMIDINES; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

MAMMALIA;

EID: 84872739633     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.437525     Document Type: Article

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